公开(公告)号：US20170327928A1

公开(公告)日：2017-11-16

申请号：US15668107

申请日：2017-08-03

Applicant: Nippon Piston Ring Co., Ltd. ,  National University Corporation Saitama University

Inventor： Shunsuke TAKEGUCHI ,  Yoshiki ISHIKAWA ,  Takasumi KUBO ,  Shin ISHIDA ,  Hiroki TAKAHASHI ,  Masafumi MORITA ,  Masahito MIKI

IPC: C22C14/00 ,  C22F1/18 ,  A61L31/02

Abstract: A titanium alloy includes 15 to 27 atomic % (at%) of tantalum (Ta) and 0 to 8 at% of tin (Sn), the balance being titanium (Ti) and unavoidable impurities, when the entire 5 amount of the titanium alloy is taken as 100 at%. Therefore, the titanium alloy provided has characteristics suitable for medical device materials, biocompatible materials, etc.

公开(公告)号：US20170246257A1

公开(公告)日：2017-08-31

申请号：US15596736

申请日：2017-05-16

Applicant: ZERIA PHARMACEUTICAL CO., LTD. ,  SAITAMA UNIVERSITY

Inventor： Takafumi SAKAI ,  Ichiro SAKATA ,  Kayuri KURODA ,  Makoto YOSHIMURA

IPC: A61K38/22 ,  A61K9/00

CPC classification number: A61K38/2214 ,  A61K9/0019 ,  A61K9/0053 ,  A61K38/22 ,  A61K38/25 ,  A61K45/06 ,  A61K2300/00

Abstract: To provide a therapeutic agent for gastrointestinal disorder such as diabetic gastroparesis. A postprandial gastrokinetic agent containing (A) ghrelin or a ghrelin agonist and (B) motilin or a motilin agonist as active ingredients, in which both the ingredients (A) and (B) are administered so as to act on the stomach after food intake.

公开(公告)号：US20150061458A1

公开(公告)日：2015-03-05

申请号：US14395053

申请日：2013-04-12

Applicant: National University Corporation Saitama University

Inventor： Kensuke Kageyama

IPC: H01G7/02 ,  H04R1/08 ,  H02N1/08

CPC classification number: H01G7/02 ,  H01G7/023 ,  H01G7/025 ,  H01G7/028 ,  H02N1/08 ,  H04R1/08 ,  H04R19/016 ,  Y10T29/49226

Abstract: An electret-structure encompasses a fluorine-resin film 21, an electrode 22 formed on one surface of the fluorine-resin film 21, and a silica layer 21 formed on another surface of the fluorine-resin film 21. The silica layer 21 is implemented by a plurality of island-shaped silica regions 201 for covering the fluorine-resin film 21 in a topology such that the island-shaped silica regions 201 are isolated from each other. And negative charges are deposited on the island-shaped silica regions 201. The static-induction conversion element with the electret-structure 1 can be mounted on a substrate by reflow-process through Pb-free solder.

Abstract translation: 驻极体结构包括氟树脂膜21，形成在氟树脂膜21的一个表面上的电极22和形成在氟树脂膜21的另一个表面上的二氧化硅层21.二氧化硅层21被实施 通过多个岛状二氧化硅区域201，用于以拓扑结构覆盖氟树脂膜21，使得岛状二氧化硅区域201彼此隔离。 并且负极电荷沉积在岛状二氧化硅区域201上。具有驻极体结构1的静电感应转换元件可以通过无铅焊料的回流处理而安装在基板上。

公开(公告)号：US20140239735A1

公开(公告)日：2014-08-28

申请号：US14343503

申请日：2012-09-07

Applicant: National University Corporation SAITAMA UNIVERSITY ,  TECHNOVA INC.

Inventor： Shigeru Abe ,  Tomio Yasuda ,  Akira Suzuki ,  Nobuhiro Hosoi

IPC: H02J17/00

CPC classification number: H02J17/00 ,  B60L3/0069 ,  B60L3/04 ,  B60L50/16 ,  B60L53/12 ,  B60L53/124 ,  B60L53/36 ,  B60L2210/30 ,  B60L2210/40 ,  B60L2240/36 ,  B60L2250/10 ,  B60L2270/147 ,  H02J7/025 ,  H02J50/10 ,  H02J50/12 ,  H02J50/60 ,  H02J50/90 ,  Y02T10/70 ,  Y02T10/7005 ,  Y02T10/7072 ,  Y02T10/7077 ,  Y02T10/7241 ,  Y02T90/12 ,  Y02T90/121 ,  Y02T90/122 ,  Y02T90/125 ,  Y02T90/127 ,  Y02T90/14

Abstract: In an example of a system, power is transferred from a transmission coil to a reception coil by electromagnetic induction. A detecting unit calculates a difference between a standard value and a measured value, detects presence of a metallic foreign object on the transmission coil based on the difference, and outputs a signal when the metallic foreign object is detected. The standard value is obtained by supplying electrical power to the transmission coil when a metallic foreign object is absent on the transmission coil. The measured value is obtained by supplying electrical power to the transmission coil. If PIN0 represents input power of the transmission coil, PL0 represents output power of the reception coil, Pc1 represents copper loss of the transmission coil, and Pc2, represents copper loss of the reception coil, the detecting unit uses a value expressed by (PIN0-PL0-Pc1-Pc2) as the standard value and the measured value.

Abstract translation: 在系统的例子中，通过电磁感应将功率从传输线圈传送到接收线圈。 检测单元计算标准值和测量值之间的差异，基于该差异检测传输线圈上的金属异物的存在，并且当检测到金属异物时输出信号。 当传输线圈上没有金属异物时，通过向传输线圈提供电力来获得标准值。 通过向发送线圈供给电力来获得测量值。 如果PIN0表示发送线圈的输入功率，则PL0表示接收线圈的输出功率，Pc1表示发送线圈的铜损，Pc2表示接收线圈的铜损，检测单元使用由（PIN0- PL0-Pc1-Pc2）作为标准值和测量值。

公开(公告)号：US20140235508A1

公开(公告)日：2014-08-21

申请号：US14265938

申请日：2014-04-30

Applicant: National University Corporation Saitama University ,  Nikon Corporation

Inventor： Naoto Nemoto ,  Shingo Ueno ,  Hirofumi Shiono

IPC: C07K17/10

CPC classification number: C07K17/10 ,  C12N15/63 ,  C12N15/67

Abstract: A nucleic acid linker is for producing a complex of mRNA and a protein encoded by that mRNA, comprising one 3′-terminal region and two branched 5′-terminal regions, wherein the 3′-terminal region comprises a single-stranded polynucleotide segment able to hybridize with the sequence on the 3′-terminal side of the mRNA, and an arm segment that branches off from the single-stranded polynucleotide segment and has a linking segment with the protein on the terminal thereof, and one of the two 5′-terminal regions has a binding site with the 3′-terminal of the mRNA.

Abstract translation: 核酸接头用于产生mRNA和由该mRNA编码的蛋白质的复合物，其包含一个3'末端区域和2个支链的5'末端区域，其中3'末端区域包含单链多核苷酸区段 与mRNA的3'-末端侧的序列杂交，和从单链多核苷酸片段分支并与其末端具有蛋白质的连接区段的臂区段，以及两个5' 末端区域具有mRNA的3'末端的结合位点。

公开(公告)号：US20230279369A1

公开(公告)日：2023-09-07

申请号：US18164700

申请日：2023-02-06

Applicant: SUMITOMO RUBBER INDUSTRIES, LTD. ,  TOHOKU UNIVERSITY ,  KANAZAWA UNIVERSITY ,  NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY

Inventor： Haruhiko YAMAGUCHI ,  Yukino INOUE ,  Seiji TAKAHASHI ,  Toru NAKAYAMA ,  Satoshi YAMASHITA ,  Yuzuru TOZAWA

IPC: C12N9/10 ,  C12N15/52 ,  C12P5/00 ,  C12N15/82

CPC classification number: C12N9/1085 ,  C12Y205/0102 ,  C12N15/52 ,  C12P5/007 ,  C12N15/8201 ,  C12N2510/00

Abstract: Provided are a mutant cis-prenyltransferase (CPT) family protein and a method for producing a polyisoprenoid, which enable the production of a high molecular weight polyisoprenoid. Included is a mutant cis-prenyltransferase (CPT) family protein obtained by mutating the amino acid sequence of a N-terminal region of a cis-prenyltransferase (CPT) family protein not found on rubber particles to be identical or similar to the amino acid sequence of a N-terminal region of a cis-prenyltransferase (CPT) family protein found on rubber particles.

公开(公告)号：US20230099615A1

公开(公告)日：2023-03-30

申请号：US18061471

申请日：2022-12-04

Applicant: National University Corporation Saitama University ,  sevensix Co., Ltd.

Inventor： Tatsutoshi SHIODA ,  Masanori NISHIURA

IPC: H01S3/1115 ,  H01S3/08 ,  H01S3/067 ,  H01S3/16

Abstract: To provide a mode-locked pulse photoproduction filter for easily realizing self-starting mode-locking, and a laser device for generating a picosecond or femtosecond-pulse laser light by including such filter, the laser device including an amplifying unit for amplifying and outputting a light inside a resonator, and the mode-locked pulse photoproduction filter having a first filter part for selectively outputting a first wavelength component that is a wavelength component of an oscillation band inside the resonator, and a second filter part for selectively outputting a second wavelength component that is a wavelength component different from the oscillation band inside the resonator.

公开(公告)号：US20210381026A1

公开(公告)日：2021-12-09

申请号：US17408423

申请日：2021-08-21

Applicant: EPSILON MOLECULAR ENGINEERING INC. ,  Saitama University

Inventor： Naoto Nemoto ,  Hironori Anzai ,  Takeru Suzuki ,  Shigefumi Kumachi ,  Takuya Terai

IPC: C12Q1/6804

Abstract: The present invention provides an improved immuno-PCR method by using cDNA display comprising the steps of: immobilizing a first antibody having a binding site to a solid phase: contacting a sample fluid to said antibody to bind a target molecule in said sample fluid; contacting said target molecule to a cDNA display being composed of a backbone being composed of a double strand and a side chain having a second antigen binding site to which the second antibody is bound; and conducting polymerase chain reaction to detect said cDNA quantitatively. According to the improved immune-PCR method of the present invention, the target molecule is screened and obtained quantitatively, because it uses cDNA display being composed of one protein/peptide and one DNA.

公开(公告)号：US20210367115A1

公开(公告)日：2021-11-25

申请号：US17422430

申请日：2019-07-11

Applicant: ASAHI RUBBER INC. ,  NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY

Inventor： Naoya MASHIKO ,  Takashi KANAHIRA ,  Masutsugu TASAKI ,  Eiji ISHIGURO ,  Keiichi WATANUKI ,  Keiichi MURAMATSU ,  Kazunori KAEDE

IPC: H01L33/50 ,  H01L33/52 ,  H01L33/60 ,  H01L33/62 ,  G02F1/13357 ,  C09K11/77

Abstract: A light source that emits light, wherein, in coordinates in a CIE 1931 chromaticity diagram, the light has a color purity included in a region of 2 to 50 in a region surrounded by a line segment WB and a line segment WG that connect coordinates W (0.33, 0.33) indicating an achromatic color with coordinates B (0.091, 0.133) of 480 nm and coordinates G (0.373, 0.624) of 560 nm on a spectral locus, and the spectral locus, and has an area occupied by a continuous spectral wavelength in a wavelength region of 480 to 540 nm, of 15% or more relative to an area of an overall spectral wavelength of the light source at 380 to 780 nm.

公开(公告)号：US10918726B2

公开(公告)日：2021-02-16

申请号：US15606334

申请日：2017-05-26

Applicant: Quarrymen & Co. Inc. ,  Saitama University

Inventor： Miho Suzuki ,  Ken Hatano ,  Shojiro Yoshida ,  Yasuhiro Yamashita

IPC: A61K47/42 ,  A61K47/24 ,  A61K38/00 ,  A61K9/10 ,  C08G83/00 ,  A61K9/00 ,  A61K9/107 ,  A61K31/7088 ,  A61K38/17 ,  A61K38/22 ,  A61K39/395

Abstract: The object of the present invention is to provide an aggregatable carrier material for drug delivery system and a micelle formed thereof. The present invention provides an aggregatable carrier material for drug delivery system, which is formed by utilizing the reaction between thiol group and alkyl halide. It is formed by using carbosilane dendrimers containing silole and labeled proteins such as green fluorescent protein in aqueous solvent or in mixed solvent of the aqueous solvent and organic solvent. The micelle composed of the material may incorporate compounds having a variety of molecular weight and biopolymers in the aqueous solvent.