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    PHANTOM FOR SPECTRAL CT IMAGE SYSTEM CALIBRATION
    12.
    发明申请
    PHANTOM FOR SPECTRAL CT IMAGE SYSTEM CALIBRATION 有权
    用于光谱CT图像系统校准的PHANTOM

    公开(公告)号：US20120155617A1

    公开(公告)日：2012-06-21

    申请号：US12968393

    申请日：2010-12-15

    Applicant: Sandeep Dutta ,  Naveen Chandra ,  Toshihiro Rifu

    Inventor： Sandeep Dutta ,  Naveen Chandra ,  Toshihiro Rifu

    IPC: G01D18/00

    CPC classification number: A61B6/583 ,  A61B6/032 ,  A61B6/06 ,  A61B6/4266 ,  A61B6/482

    Abstract: A phantom includes a housing enclosing an interior volume and having a plurality of passages formed therein, wherein each passage is fluidly isolated from the interior volume. First and second inserts are included and configured to be positioned in a first passage of the plurality of passages and include materials having a known material density. The material is selected from iodine, hydroxyapatite (HAP), tricalcium phosphate (TCP), body fat, fatty plaque, sodium chloride (NaCl), gold (Au), and iron (Fe). The material of the inserts can be different materials or the same material at different densities.

    Abstract translation: 体模包括封闭内部容积并具有形成在其中的多个通道的壳体，其中每个通道与内部容积流体隔离。 第一和第二插入件被包括并构造成定位在多个通道的第一通道中并且包括具有已知材料密度的材料。 该材料选自碘，羟基磷灰石（HAP），磷酸三钙（TCP），体脂肪，脂肪斑块，氯化钠（NaCl），金（Au）和铁（Fe）。 插入物的材料可以是不同的材料或不同密度的相同材料。

    ABUSE RESISTANT MELT EXTRUDED FORMULATION HAVING REDUCED ALCOHOL INTERACTION
    14.
    发明申请
    ABUSE RESISTANT MELT EXTRUDED FORMULATION HAVING REDUCED ALCOHOL INTERACTION 审中-公开
    具有降低酒精相互作用的抗菌熔体挤压配方

    公开(公告)号：US20100172989A1

    公开(公告)日：2010-07-08

    申请号：US12631010

    申请日：2009-12-04

    Applicant: Wolfgang Roth ,  Alexander Burst ,  Martina Zietsch ,  Wei Liu ,  Sandeep Dutta

    Inventor： Wolfgang Roth ,  Alexander Burst ,  Martina Zietsch ,  Wei Liu ,  Sandeep Dutta

    IPC: A61K9/14 ,  A61K31/485 ,  A61P25/04

    CPC classification number: A61K9/2027 ,  A61K9/2031 ,  A61K9/2054 ,  A61K9/209 ,  A61K9/2095 ,  A61K31/167 ,  A61K31/192 ,  A61K31/277 ,  A61K31/485

    Abstract: The present invention relates to compositions for oral administration. The invention preferably comprises at least one abuse-resistant drug delivery composition for delivering a drug having potential for dose dumping in alcohol, related methods of preparing these dosage forms, and methods of treating a patient in need thereof comprising administering the inventive compositions to the patient. Most preferably, the dosage form includes verapamil. These formulations have reduced potential for abuse. In another formulation, preferably the abuse relevant drug is an opioid and the non-abuse relevant drug is acetaminophen or ibuprofen. More preferably, the opioid is hydrocodone, and the non-abuse relevant analgesic is acetaminophen. In certain preferred embodiments, the dosage forms are characterized by resistance to solvent extraction; tampering, crushing or grinding. Certain embodiments of the inventions provide dosage forms that provide an initial burst of release of drug followed by a prolonged period of controllable drug release.

    Abstract translation: 本发明涉及用于口服给药的组合物。 本发明优选包含至少一种用于递送具有在醇中倾倒剂量的药物的药物递送组合物，制备这些剂型的相关方法和治疗有需要的患者的方法包括将本发明组合物施用于患者 。 最优选地，剂型包括维拉帕米。 这些制剂减少了滥用的可能性。 在另一种制剂中，优选滥用相关药物是阿片样物质，非滥用相关药物是对乙酰氨基酚或布洛芬。 更优选地，阿片样物质是氢可酮，非滥用相关镇痛药是对乙酰氨基酚。 在某些优选的实施方案中，剂型的特征在于耐溶剂萃取; 篡改，破碎或研磨。 本发明的某些实施方案提供剂型，其提供药物释放的初始爆发，随后延长药物释放时间。

    Method and apparatus for 3D reconstruction of images
    15.
    发明授权
    Method and apparatus for 3D reconstruction of images 有权
    图像三维重建的方法和装置

    公开(公告)号：US07583777B2

    公开(公告)日：2009-09-01

    申请号：US10895704

    申请日：2004-07-21

    Applicant: Xiangyang Tang ,  Jiang Hsieh ,  Sandeep Dutta ,  Roy Arnulf Helge Nilsen

    Inventor： Xiangyang Tang ,  Jiang Hsieh ,  Sandeep Dutta ,  Roy Arnulf Helge Nilsen

    IPC: A61B6/00

    CPC classification number: A61B6/032 ,  A61B6/027 ,  A61B6/583 ,  G06T11/005

    Abstract: A method for producing an image of an object includes scanning an object with an imaging apparatus to collect projection data of the object utilizing cone sampling. The projection data is rebinned in a row-wise, fan-to-parallel fashion to produce rebinned data and the rebinned data is view-weighted to produce view-weighted data. The method further includes filtering the view-weighted data utilizing a row-wise ramp filter to produce filtered data and generating an image of the object utilizing the filtered data and a three-dimensional (3D) backprojection.

    Abstract translation: 用于产生对象的图像的方法包括用成像装置扫描对象，以采用锥形采样来收集对象的投影数据。 投影数据以行方式，扇形到并行的方式重新组合，以产生重新排列的数据，并且重新定位的数据被视图加权以产生视图加权数据。 该方法还包括利用逐行斜坡滤波器对视图加权数据进行滤波，以产生滤波数据，并利用滤波数据和三维（3D）反投影产生对象的图像。

    METHOD AND SYSTEM FOR DETECTION OF OBSTRUCTIONS IN VASCULATURE
    16.
    发明申请
    METHOD AND SYSTEM FOR DETECTION OF OBSTRUCTIONS IN VASCULATURE 审中-公开
    用于检测血管阻塞的方法和系统

    公开(公告)号：US20090012382A1

    公开(公告)日：2009-01-08

    申请号：US11772654

    申请日：2007-07-02

    Applicant: Sandeep Dutta ,  Ajay Gopinath ,  Srikanth Suryanarayanan ,  Arunabha Shasanka Roy ,  Paulo Ricardo Dos Santos Mendonca

    Inventor： Sandeep Dutta ,  Ajay Gopinath ,  Srikanth Suryanarayanan ,  Arunabha Shasanka Roy ,  Paulo Ricardo Dos Santos Mendonca

    IPC: A61B6/00

    CPC classification number: A61B6/504 ,  A61B5/02007 ,  A61B5/055 ,  A61B5/489 ,  A61B6/032 ,  A61B6/481 ,  G06T7/0012 ,  G06T2207/30101

    Abstract: A method for automatic detection of obstructions in vasculature in an anatomical region is presented. The method includes partitioning the anatomical region into a plurality of sub-regions based at least in part on anatomical knowledge. Further, the method includes adaptively computing a threshold intensity value corresponding to each of the plurality of sub-regions. Additionally, the method includes extracting the vasculature in each of the plurality of sub-regions based on the corresponding computed threshold intensity value, where the extracted vasculature comprises a plurality of vessel segments. The method also includes detecting an obstruction in the extracted vasculature. Systems and computer-readable medium that afford functionality of the type defined by this method is also contemplated in conjunction with the present technique.

    Abstract translation: 提出了一种自动检测解剖区域脉管系统阻塞物的方法。 该方法包括至少部分地基于解剖学知识将解剖区域划分成多个子区域。 此外，该方法包括自适应地计算与多个子区域中的每一个对应的阈值强度值。 另外，该方法包括基于对应的计算的阈值强度值来提取多个子区域中的每个子区域中的脉管系统，其中提取的脉管系统包括多个血管段。 该方法还包括检测提取的脉管系统中的梗阻。 提供由该方法定义的类型的功能的系统和计算机可读介质也结合本技术考虑。

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