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    Photo-stable cosmetic and pharmaceutical formulations containing UV-filters
    13.
    发明授权
    Photo-stable cosmetic and pharmaceutical formulations containing UV-filters 失效
    光稳定的化妆品和药物配方含有紫外线过滤器

    公开(公告)号：US5945091A

    公开(公告)日：1999-08-31

    申请号：US972391

    申请日：1997-11-18

    Applicant: Thorsten Habeck ,  Alexander Aumuller ,  Volker Schehlmann ,  Horst Westenfelder ,  Thomas Wunsch

    Inventor： Thorsten Habeck ,  Alexander Aumuller ,  Volker Schehlmann ,  Horst Westenfelder ,  Thomas Wunsch

    IPC: A61K8/30 ,  A61K8/00 ,  A61K8/41 ,  A61K8/42 ,  A61K8/46 ,  A61K8/49 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  A61Q19/00 ,  C07C229/56 ,  C07C229/60 ,  C07C255/30 ,  C07C255/58 ,  C07C309/46 ,  C07D275/02 ,  C07D275/03 ,  C07D319/06 ,  C07D333/38 ,  A61K7/42 ,  A61K7/00 ,  A61K31/255 ,  A61K31/275 ,  A61K31/66

    CPC classification number: C07D275/03 ,  A61K8/411 ,  A61K8/42 ,  A61K8/466 ,  A61K8/49 ,  A61K8/498 ,  A61K8/4986 ,  A61Q1/04 ,  A61Q17/04 ,  C07C229/56 ,  C07C229/60 ,  C07C255/30 ,  C07C255/58 ,  C07C309/46 ,  C07D319/06 ,  C07D333/38 ,  A61K2800/52

    Abstract: A method of using compounds of formula I ##STR1## in which the C.dbd.C double bond is present in E and/or Z configuration and the variables have the following meanings:R.sup.1 denotes COOR.sup.5, COR.sup.5, CONR.sup.5 R.sup.6, CN, O.dbd.S(--R.sup.5).dbd.O, O.dbd.S(--OR.sup.5).dbd.O, R.sup.7 O--P(--OR.sup.8).dbd.O;R.sup.2 denotes COOR.sup.6, COR.sup.6, CONR.sup.5 R.sup.6, CN, O.dbd.S(--R.sup.6).dbd.O, O.dbd.S(--OR.sup.6).dbd.O, R.sup.7 O--P(--OR.sup.8).dbd.O;R.sup.3 denotes hydrogen, an optionally substituted aliphatic, cycloaliphatic, araliphatic or aromatic radical having in each case up to 18 carbon atoms;R.sup.4 denotes an optionally substituted aromatic or heteroaromatic radical containing from 5 to 12 ring atoms;R.sup.5 toR.sup.8 independently denote hydrogen, an open-chain or branched-chain aliphatic, araliphatic, cycloaliphatic or optionally substituted aromatic radical containing in each case up to 18 carbon atoms,where the variables R.sup.3 to R.sup.8 may also form, together with the carbon atoms to which they are attached, a 5-membered or 6-membered ring, which may be anellated if desired,as UV filters, particularly UV-A filters, in cosmetic and pharmaceutical formulations for the protection of the human skin or human hair from solar radiation, alone or together with compounds known per se in cosmetic and pharmaceutical formulations and capable of absorbing radiation in the UV range.

    Abstract translation: 在E和/或Z构型中使用存在C = C双键的式I化合物的方法，并且变量具有以下含义：R 1表示COOR 5，COR 5，CONR 5 R 6，CN，O = S（-R 5） = O，O = S（-OR 5）= O，R 7 O-P（-OR 8）= O; R2表示COOR6，COR6，CONR5R6，CN，O = S（-R6）= O，O = S（-OR6）= O，R7O-P（-OR8）= O; R 3表示氢，任选取代的脂族，脂环族，芳脂族或芳族基团，其在每种情况下最多为18个碳原子; R4表示任选取代的芳族或杂芳族基团，其含有5至12个环原子; R5至R8独立地表示氢，开链或支链脂族，芳脂族，脂环族或任选取代的芳族基团，其在每种情况下含有至多18个碳原子，其中变量R3至R8也可与碳原子一起形成 它们所连接的是5元或6元环，如果需要，可以作为UV过滤剂，特别是UV-A过滤器，在用于保护人类皮肤或人类头发免受太阳能的化妆品和药物制剂中的影响 单独或与化妆品和药物制剂中本身已知的化合物一起辐射并且能够吸收UV范围内的辐射。

    Crosslinked, water-soluble or water-dispersible polyurethanes
    16.
    再颁专利
    Crosslinked, water-soluble or water-dispersible polyurethanes 有权
    交联的水溶性或水分散性聚氨酯

    公开(公告)号：USRE41615E1

    公开(公告)日：2010-08-31

    申请号：US11165555

    申请日：2005-06-24

    Applicant: Son Nguyen Kim ,  Axel Sanner ,  Peter Hössel ,  Volker Schehlmann

    Inventor： Son Nguyen Kim ,  Axel Sanner ,  Peter Hössel ,  Volker Schehlmann

    IPC: C08G18/62

    CPC classification number: A61K8/046 ,  A61K8/87 ,  A61Q5/06 ,  C08G18/0819 ,  C08G18/12 ,  C08G18/3212 ,  C08G18/4018 ,  C08G18/4216 ,  C08G18/4854 ,  C08G18/6229 ,  C08G18/6254 ,  C08G18/6283 ,  C08G18/6625 ,  C08G18/6659 ,  C08G18/6692 ,  C08G18/755 ,  C08G18/307

    Abstract: The present invention relates to crosslinked, water-soluble or water-dispersible polyurethanes of A) at least one water-soluble or water-dispersible polyurethane prepolymer having terminal isocyanate groups of a) at least one compound having a molecular weight in the range from 56 to 300 which contains two active hydrogen atoms per molecule, b) at least one polymer containing two active hydrogen atoms per molecule, c) at least one compound which contains two active hydrogen atoms and at least one ionogenic or ionic group per molecule, d) at least one diisocyanate, B) at least one polymer containing groups which are reactive toward isocyanate groups, chosen from hydroxyl, and primary and secondary amino and/or carboxyl groups, or the salts thereof.

    Abstract translation: 本发明涉及交联的水溶性或水分散性聚氨酯，A）至少一种具有末端异氰酸酯基团的水溶性或水分散性聚氨酯预聚物，其具有a）至少一种分子量范围为56 至300，每分子含有两个活性氢原子，b）每分子含有两个活性氢原子的至少一种聚合物，c）至少一种含有两个活性氢原子和每个分子至少一个离子基团或离子基团的化合物，d） 至少一种二异氰酸酯，B）含有选自羟基，伯和仲氨基和/或羧基的异氰酸酯基反应性基团的至少一种聚合物或其盐。

    Use of isoindolinone derivatives as stabilizers for organic materials
    20.
    发明授权
    Use of isoindolinone derivatives as stabilizers for organic materials 失效
    异吲哚啉酮衍生物作为有机材料的稳定剂的使用

    公开(公告)号：US06210657B1

    公开(公告)日：2001-04-03

    申请号：US09207624

    申请日：1998-12-09

    Applicant: Thorsten Habeck ,  Sylke Haremza ,  Hubert Trauth ,  Volker Schehlmann ,  Horst Westenfelder

    Inventor： Thorsten Habeck ,  Sylke Haremza ,  Hubert Trauth ,  Volker Schehlmann ,  Horst Westenfelder

    IPC: A61K742

    CPC classification number: A61K31/4035 ,  C08K5/3417 ,  C09D7/48 ,  C09K15/30 ,  Y10S514/844 ,  Y10S514/97 ,  Y10S514/972

    Abstract: Isoindolinone derivatives of the formula I, in which the variables have the following meanings: R1 is hydrogen, COOR4, COR4, CONR4R5, CN, C1-C20-alkyl, C2-C10-alkenyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl, aryl or heteroaryl, substituted or unsubstituted; R1 and R2 together are C7-C10-bicycloalkyl or C7-C10-bicycloalkenyl; R3 is hydrogen, C1-C20-alkyl, C2-C10-alkenyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl, C1-C12-alkoxy, C1-C20-alkoxycarbonyl, C1-C12-alkylamino, C1-C12-dialkylamino, aryl or heteroaryl, substituted or unsubstituted, substituents which confer solubility in water, selected from the group consisting of carboxylate, sulfonate or ammonium radicals; R4 and R5 independently of one another are hydrogen, C1-C20-alkyl, C2-C10-alkenyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl; aryl or heteroaryl, substituted or unsubstituted; are used as stabilizers for organic materials.

    Abstract translation: 式I的异吲哚啉酮衍生物，其中变量具有以下含义：R1是氢，COOR4，COR4，CONR4R5，CN，C1-C20-烷基，C2-C10-烯基，C3-C10-环烷基，C3-C10- 环烯基，芳基或杂芳基，取代或未取代的; R1和R2一起是C7-C10-双环烷基或C7-C10-双环烯基; R3是氢，C1-C20-烷基，C2-C10-烯基，C3-C10-环烷基，C3 -C 10 - 环烯基，C 1 -C 12 - 烷氧基，C 1 -C 20 - 烷氧基羰基，C 1 -C 12 - 烷基氨基，C 1 -C 12 - 二烷基氨基，芳基或杂芳基，取代或未取代的赋予水溶性的取代基， 羧酸酯，磺酸酯或铵基; R 4和R 5彼此独立地是氢，C 1 -C 20 - 烷基，C 2 -C 10 - 烯基，C 3 -C 10 - 环烷基，C 3 -C 10 - 环烯基; 芳基或杂芳基，取代或未取代的;被用作有机材料的稳定剂。

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