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    Methods ablating tissue using a catheter-based injection system
    13.
    发明授权
    Methods ablating tissue using a catheter-based injection system 有权
    使用基于导管的注射系统消融组织的方法

    公开(公告)号：US09131983B2

    公开(公告)日：2015-09-15

    申请号：US14057972

    申请日：2013-10-18

    Applicant: Ablative Solutions, Inc.

    Inventor： David R. Fischell ,  Tim A. Fischell

    IPC: A61M31/00 ,  A61B18/14 ,  A61M5/00 ,  A61B18/00

    CPC classification number: A61B18/1492 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00375 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/143 ,  A61M5/00

    Abstract: At the present time, physicians often treat patients with atrial fibrillation (AF) using radiofrequency (RF) catheter systems to ablate conducting tissue in the wall of the Left Atrium of the heart around the ostium of the pulmonary veins. These systems are expensive and take time consuming to use. The present invention circular ablation system CAS includes a multiplicity of expandable needles that can be expanded around a central axis and positioned to inject a fluid like ethanol to ablate conductive tissue in a ring around the ostium of a pulmonary vein quickly and without the need for expensive capital equipment. The expansion of the needles is accomplished by self-expanding or balloon expandable structures. The invention includes centering means so that the needles will be situated in a pattern surrounding the outside of the ostium of a vein. Also included are members that limit the distance of penetration of the needles into the wall of the left atrium. The present invention also has application to ablating tissue around the ostium of a renal artery for the treatment of hypertension.

    Abstract translation: 目前，医生经常使用射频（RF）导管系统治疗房颤患者，以消融肺静脉周围心脏左心房壁的导电组织。 这些系统是昂贵的并且花费耗时的使用。 本发明的圆形消融系统CAS包括多个可扩展的针，其可以围绕中心轴线扩张并且被定位成像乙醇一样注入流体，以便快速地在肺静脉的口周围环绕环中的导电组织，而不需要昂贵的 资本设备。 针的膨胀通过自膨胀或球囊可膨胀结构来实现。 本发明包括定心装置，使得针头将位于围绕静脉口的外侧的图案中。 还包括限制针头进入左心房壁的距离的成员。 本发明还可用于消除肾动脉口周围的组织用于治疗高血压。

    METHOD AND APPARATUS FOR SPARING PAIN CONDUCTING NERVES DURING RENAL DENERVATION
    14.
    发明申请
    METHOD AND APPARATUS FOR SPARING PAIN CONDUCTING NERVES DURING RENAL DENERVATION 审中-公开
    用于在肾衰竭期间产生疼痛导致神经的方法和装置

    公开(公告)号：US20150119875A1

    公开(公告)日：2015-04-30

    申请号：US14064077

    申请日：2013-10-25

    Applicant: Ablative Solutions, Inc.

    Inventor： David R. Fischell ,  Tim A. Fischell ,  Vartan Ghazarossian ,  Steven Almany

    IPC: A61B18/14

    CPC classification number: A61B18/1492 ,  A61B2018/00214 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1475

    Abstract: An intravascular catheter for peri-vascular nerve activity ablation and/or sensing includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Ablative energy or fluid is delivered from the needles in or near the adventitia to ablate nerves outside of the media while sparing nerves within the media.

    Abstract translation: 用于周围血管神经活动消融和/或感测的血管内导管包括通过支撑的导管（针引导元件）前进的多个针，其以围绕中心轴线的开口端膨胀以接触肾动脉壁或其它的内壁 人体的血管允许针通过血管壁进入血管周围空间。 导管还包括向引导管提供径向和横向支撑的结构，使得引导管均匀地打开并且当尖锐的针被推进以穿透到血管壁时，它们保持其抵靠血管壁的内表面的位置。 烧蚀能量或液体从外膜中或附近的针头输送，以消除介质外部的神经，同时将神经保持在介质内。

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