中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

26 records (took 0.015 seconds)

    Wettable silicone hydrogel contact lenses
    14.
    发明授权
    Wettable silicone hydrogel contact lenses 有权

    公开(公告)号：US11513257B2

    公开(公告)日：2022-11-29

    申请号：US17122109

    申请日：2020-12-15

    Applicant: Alcon Inc.

    Inventor： Ying Zheng ,  Jang-Shing Chiou ,  Jinbo Dou ,  Yuan Chang ,  Junhao Ge ,  Steve Yun Zhang ,  Li Yao ,  Karen Belinda Sentell ,  Ye Hong

    IPC: C08L39/06 ,  G02B1/04 ,  B65B25/00 ,  C08L71/02 ,  C08L83/04 ,  G02C7/04

    Abstract: The invention relates to an ophthalmic product which comprises a sealed and autoclave-sterilized lens package including (1) a post-autoclave packaging solution containing a polymeric surfactant having an HLB value of from about 11 to about 16 and a Mn of from about 800 to about 20,000 Daltons and (2) a readily-usable silicone hydrogel (SiHy) contact lens immersed in the packaging solution. The readily-usable SiHy contact lens comprises the polymeric surfactant thereon providing an excellent wettability to the readily-usable SiHy contact lens directly out of the lens package, and also the leachable polymeric surfactant which is physically distributed in the polymer matrix of the SiHy contact lens and can be released to the eye of a patient for at least 7 days of daily wear and to replenish the lens surface-bound polymeric surfactant to provide sustainable wettabilities to the contact lens and the eye.

    PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS
    16.
    发明申请
    PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS 有权

    公开(公告)号：US20210284778A1

    公开(公告)日：2021-09-16

    申请号：US17197460

    申请日：2021-03-10

    Applicant: Alcon Inc.

    Inventor： Yuan Chang ,  Junhao Ge ,  Steve Yun Zhang ,  Weihong Lang

    IPC: C08F283/12 ,  G02B1/04 ,  C08G77/06 ,  C08G77/442 ,  C08L83/12 ,  C09K9/02

    Abstract: The invention provides a class of photochromic polydiorganosiloxane vinylic crosslinkers. Each of the photochromic polydiorganosiloxane vinylic crosslinkers of the invention comprise (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and photochromic siloxane unit having one methyl substituent and one organic substituent having a photochromic moiety that capable of undergoing a reversible color change upon exposure to UV-irradiation or high-energy-violet light; (2) two terminal ethylenically-unsaturated groups. The invention also provides a soft photochromic contact lens, especially a photochromic silicone hydrogel contact lens, which comprises a crosslinked polymeric material comprising repeating units of at least one of such a class of photochromic polydiorganosiloxane vinylic crosslinkers. The invention further provides a method of producing a photochromic contact lens from a polymerizable composition comprising at least one of such a class of photochromic polydiorganosiloxane vinylic crosslinkers.

    Method for making photochromic contact lenses
    18.
    发明授权
    Method for making photochromic contact lenses 有权

    公开(公告)号：US11975499B2

    公开(公告)日：2024-05-07

    申请号：US17518432

    申请日：2021-11-03

    Applicant: Alcon Inc.

    Inventor： Yuan Chang ,  Junhao Ge ,  Steve Yun Zhang

    IPC: C08F2/48 ,  B29D11/00 ,  G02B1/04

    CPC classification number: B29D11/00048 ,  C08F2/48 ,  G02B1/043

    Abstract: Described herein is a method for producing photochromic contact lenses, in particular, photochromic silicone hydrogel contact lenses. The method comprises a step of cast molding of a lens-forming composition including a vinylic monomer having a primary amino or thiolactone group to form an unprocessed contact lens having the polymer matrix of which have pendant primary amino or thiolactone groups, a step of one-pot multistep reactions based on thiolactone chemistry (aminolysis and thiol-induced graft polymerization of a photochromic vinylic monomer to the polymer matrix) which are carried out only in its central region which is circular and concentric with the central axis of the unprocessed contact lens. The obtained photochromic contact lens has a central pupillary region that only can undergo a reversible color change upon exposure to UV/HEVL-radiation.

    METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES
    20.
    发明申请
    METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES 有权

    公开(公告)号：US20220339895A1

    公开(公告)日：2022-10-27

    申请号：US17710248

    申请日：2022-03-31

    Applicant: Alcon Inc.

    Inventor： Yuan Chang ,  Junhao Ge ,  Steve Yun Zhang ,  Michelle Plavnik ,  Yang Zheng ,  Jing Cheng ,  Augustine Twum Kumi

    IPC: B29D11/00 ,  C08L83/14 ,  G02C7/04 ,  G02C7/10

    Abstract: Described herein is a method for producing a contact lens comprising a central photochromic zone that has a diameter of about 13 mm or less and is concentric with the central axis of the contact lens. The method comprises: applying, in the center of the molding surface of a male mold half, a drop (having a volume of about 5 μL or less) of a first polymerizable fluid composition containing at least one photochromic compound and a relatively-high molecular weight polysiloxane vinylic crosslinker for increasing the viscosity and adhesion on the molding surface of the male mold half; dosing a second polymerizable fluid composition in a female mold hald; closing the female mold hald with the male mold half with the drop thereon to form a molding assembly; and curing the second polymerizable fluid composition and the drop of the first polymerizable fluid composition in the molding assembly.

Patent Agency Ranking