Abstract:
Disclosed is a method for fabricating a stent, the method comprising: positioning a polymeric tube inside a mold, wherein a high thermally conductive element covers at least a portion of the outer surface of the mold, the high thermally conductive element having a thermal conductivity that is greater than that of the mold; heating at least a portion of the mold; radially expanding the tube against the mold; and fabricating a stent from the radially expanded tube.
Abstract:
Described here are delivery devices for delivering one or more implants to the body, and methods of using. The delivery devices may deliver implants to a variety of locations within the body, for a number of different uses. In some variations, the delivery devices have a cannula with one or more curved sections. In some variations, a pusher may be used to release one or more implants from the cannula. In some variations, one or more of the released implants may be a self-expanding device. Methods of delivering implants to one or more sinus cavities are also described here.
Abstract:
Described here are delivery devices for delivering one or more implants to the body, and methods of using. The delivery devices may deliver implants to a variety of locations within the body, for a number of different uses. In some variations, the delivery devices have a cannula with one or more curved sections. In some variations, a pusher may be used to release one or more implants from the cannula. In some variations, one or more of the released implants may be a self-expanding device. Methods of delivering implants to one or more sinus cavities are also described here.
Abstract:
Provided herein is a method of forming medical device that includes RGD attached to the device via a spacer compound. The method comprises providing a spacer compound comprising a hydrophobic moiety and a hydrophilic moiety, grafting or embedding the spacer compound to the surface layer of the polymer to cause the hydrophobic moiety to be grafted to or embedded within the surface layer of polymer, and attaching a chemo-attractant to the hydrophilic moiety.
Abstract:
A method of manufacturing a radially expandable an implantable medical device, the method comprising: providing a plurality of fibers, the fibers comprising a polymer; disposing the plurality of fibers on a cylindrical support element to form a tubular structure, the tubular structure having an initial diameter; heat setting the tubular structure such that the temperature of the tubular structure is between Tg to Tm of the polymer while heat setting, wherein the tubular structure is maintained at a heat set diameter which is equal to or substantially equal to the initial diameter; and fabricating an implantable medical device from the tubular structure.
Abstract:
A stent includes a marker that has a biodegradable body and a plurality of radiopaque nanoparticles dispersed in the body. The marker is disposed in a hole on a biodegradable structural element of the stent, and the marker and the hole have substantially the same configuration. A method for making a stent includes mixing radiopaque nanoparticles with a biodegradable material to form a stent marker, forming a hole on a structural element of a biodegradable stent for accommodating the stent marker, wherein the stent marker and hole have substantially the same configuration, and disposing the stent marker in the hole.
Abstract:
Described here are devices and methods for crimping self-expanding devices. The crimping devices may be useful for crimping a variety of different self-expanding devices (whether such devices are biodegradable or bio-durable). The crimping devices may have crimping members to engage the self-expanding device to reduce the device from an expanding configuration to an unexpanded configuration. The crimping member may comprise or include a suture, wire, ribbon, guiding hoop, pusher, prong, holding bar, balloon, jaws, combinations thereof, or the like. The crimping devices may also include or comprise a holding structure to hold the self-expanding device in an unexpanded or expanded configuration.