公开(公告)号：US20150353971A1

公开(公告)日：2015-12-10

申请号：US14813804

申请日：2015-07-30

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Sol M. Resnick ,  Michael Mendez ,  Renee M. Saville ,  Sungwon Lee ,  Luan Nguyen

IPC: C12P7/64 ,  C12N9/10 ,  C12N9/00 ,  C12N9/16

CPC classification number: C12P7/6409 ,  C10G3/00 ,  C10G3/50 ,  C10G47/00 ,  C10G2300/1014 ,  C10L1/02 ,  C10L1/04 ,  C10L2200/0469 ,  C10L2270/02 ,  C10L2270/04 ,  C10L2290/26 ,  C12N1/16 ,  C12N1/20 ,  C12N9/1029 ,  C12N9/16 ,  C12N9/93 ,  C12N15/52 ,  C12N15/74 ,  C12P5/00 ,  C12P7/6463 ,  C12P7/649 ,  C12R1/01 ,  C12Y203/01039 ,  C12Y301/02 ,  C12Y602/01003 ,  C12Y604/01002 ,  Y02E50/13 ,  Y02E50/343 ,  Y02P20/52 ,  Y02P30/20

Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.

Abstract translation: 本公开涉及用于生产生物燃料的生物工程方法，特别是使用C1代谢微生物反应器系统来将C1底物如甲烷或甲醇转化为生物质，随后转化为生物燃料，生物塑料等。

公开(公告)号：US10889842B2

公开(公告)日：2021-01-12

申请号：US14599383

申请日：2015-01-16

Applicant: CALYSTA, INC.

Inventor： Renee M. Saville ,  Joshua A. Silverman ,  Eric G. Luning ,  Brandon D. Doss ,  Lorraine Joan Giver ,  Sol M. Resnick ,  Drew D. Regitsky

IPC: C12N1/04 ,  C12N1/32 ,  C12P13/08 ,  C12P13/12 ,  C12N15/52 ,  C12N1/30

Abstract: The present disclosure relates to recombinant microorganisms engineered for enhance production of a desired amino acid, as well as related biomass, and compositions which are useful, inter alia, as animal feed ingredients. The present invention also provides related methods.

公开(公告)号：US10889793B2

公开(公告)日：2021-01-12

申请号：US15639120

申请日：2017-06-30

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Sol M. Resnick ,  Drew D. Regitsky

IPC: C12M1/02 ,  C12M1/04 ,  C12M1/08 ,  C12P5/02 ,  C12P7/16 ,  C12P7/18 ,  C12P7/40 ,  C12P7/42 ,  C12P17/02 ,  C12N1/08 ,  C12N1/10 ,  C12N1/12 ,  C12N1/20 ,  C12N13/00 ,  C02F3/32 ,  A01G33/00 ,  C12M1/00 ,  C12M1/12

Abstract: A fermenter can have at least one hollow fluid conduit disposed at least partially within a vessel. An external circumference of the hollow fluid conduit and an interior circumference of the vessel can define a downward flow path through which a multi-phase mixture including a liquid media and compressed gas substrate bubbles flows. An interior circumference of the hollow fluid conduit can defined an upward flow path which is in fluid communication with the downward flow path. The multi-phase liquid can flow through the upward flow path and exit the fermenter. Cooling may be provided in the hollow fluid conduit or the vessel. One or more backpressor generators can be used to maintain a backpressure on the fermenter. One or more fluid movers can be used to variously create an induced and/or forced flow in the downward and upward flow paths.

公开(公告)号：US10450548B2

公开(公告)日：2019-10-22

申请号：US14898948

申请日：2014-06-18

Applicant: CALYSTA, INC.

Inventor： Renee M. Saville ,  Sungwon Lee ,  Drew D. Regitsky ,  Sol M. Resnick ,  Joshua A. Silverman

IPC: C12N1/20 ,  C12N9/04 ,  C12P7/56 ,  C07B59/00 ,  C07C59/08 ,  C12N15/74

Abstract: The present disclosure provides non-naturally occurring c1 microorganisms useful for the production of lactate and related compositions, as well as methods for the biologically production of lactate. In specific embodiments, the present disclosure provides non-naturally occurring methanotrophic bacteria which are useful for producing lactate from c1 substrates.