公开(公告)号：US09446202B2

公开(公告)日：2016-09-20

申请号：US13395599

申请日：2010-09-29

Applicant: Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

Inventor： Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

IPC: A61M5/315 ,  A61M5/24

CPC classification number: A61M5/31543 ,  A61M5/31535 ,  A61M5/31555 ,  A61M5/3156 ,  A61M5/3158 ,  A61M5/31593 ,  A61M2005/2407

Abstract: A plunger (4) having engaging means and a lever (5) are arranged in a body (1). The lever has a first pivot that is stationary with respect to the body in the direction of an axis, a second pivot, and a third pivot formed by an engaging element of the lever. The pivots are arranged in such a manner that a rotation of the lever with respect to the first pivot moves the second pivot and the third pivot in the same direction with respect to the axis. The engaging element and the engaging means are shaped such that the lever is disengaged from the plunger when the second pivot is moved relatively to the plunger in the proximal direction (30), and the plunger is engaged with the lever when the second pivot is moved in the distal direction (20).

Abstract translation: 具有接合装置和杆（5）的柱塞（4）布置在主体（1）中。 所述杠杆具有第一枢轴，所述第一枢轴在轴线方向相对于所述主体固定，第二枢轴和由所述杠杆的接合元件形成的第三枢轴。 所述枢轴以这样的方式设置，即所述杆相对于所述第一枢轴的旋转使所述第二枢轴和所述第三枢轴沿相对于所述轴线的相同方向移动。 接合元件和接合装置的形状使得当第二枢轴在近端方向（30）相对于柱塞移动时，杠杆与柱塞脱离，并且当第二枢轴移动时，柱塞与杠杆接合 在远端方向（20）。

公开(公告)号：US09402962B2

公开(公告)日：2016-08-02

申请号：US13497375

申请日：2010-09-29

Applicant: Catherine Anne Macdonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Andrew Mark Lindsay

Inventor： Catherine Anne Macdonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Andrew Mark Lindsay

IPC: A61M5/00 ,  A61M5/315 ,  A61M5/31 ,  A61M5/24

CPC classification number: A61M5/31593 ,  A61M5/24 ,  A61M5/3146 ,  A61M5/31501 ,  A61M5/31511 ,  A61M5/31555 ,  A61M2005/2407 ,  A61M2205/581

Abstract: The present invention relates to an assembly for a drug delivery device comprising a proximal end, a distal end and a moveable member, a dose member, a fixed member and coupling means, wherein in a first state, the moveable member is moveable in an axial direction with respect to the fixed member and the dose member and the coupling means retains the dose member to the fixed member, and wherein in a second state of the assembly, the moveable member is permanently connected with the dose member by means of the coupling means and the dose member is released from the fixed member and the assembly is configured to set and dispense a dose of a fluid medicinal product out of an assembled cartridge by movement of the dose member. Furthermore it relates to a method for setting-up a drug delivery device.

Abstract translation: 本发明涉及一种用于药物输送装置的组件，其包括近端，远端和可移动构件，剂量构件，固定构件和联接装置，其中在第一状态下，可移动构件可在轴向 相对于固定构件和剂量构件的方向，并且联接装置将剂量构件保持到固定构件，并且其中在组件的第二状态下，可移动构件通过联接装置永久地与剂量构件连接 并且剂量构件从固定构件释放，并且组件构造成通过剂量构件的移动来将流体药物的剂量设置和分配出组装的筒。 此外，它涉及一种用于设置药物递送装置的方法。

公开(公告)号：US09402960B2

公开(公告)日：2016-08-02

申请号：US13395898

申请日：2010-09-29

Applicant: Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne Macdonald

Inventor： Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne Macdonald

IPC: A61M5/315 ,  A61M5/24

CPC classification number: A61M5/31535 ,  A61M5/24 ,  A61M5/31543 ,  A61M5/31555 ,  A61M5/3156 ,  A61M5/3158 ,  A61M5/31593 ,  A61M2005/2407

Abstract: A plunger and a lever are arranged in a body and provided with engaging elements engaging the lever with the plunger. The lever is disengageable from the plunger by a shift of the lever, thus enabling a movement of the plunger relatively to the body in the proximal direction.

Abstract translation: 柱塞和杠杆布置在主体中并且设置有与杠杆与柱塞接合的接合元件。 杠杆通过杠杆的移动而与柱塞脱离，从而使得柱塞能够在近端方向上相对于身体移动。

公开(公告)号：US20160217452A1

公开(公告)日：2016-07-28

申请号：US15091253

申请日：2016-04-05

Applicant: Erick Wong ,  Christian Flurscheim ,  Oleg Makhotin ,  Eduardo Lopez ,  Sanjeev Sharma ,  Christopher Jones ,  Abhishek Guglani ,  Jarkko Oskari Sevanto ,  Bharatkumar Patel ,  Tai Lung Burnnet Or

Inventor： Erick Wong ,  Christian Flurscheim ,  Oleg Makhotin ,  Eduardo Lopez ,  Sanjeev Sharma ,  Christopher Jones ,  Abhishek Guglani ,  Jarkko Oskari Sevanto ,  Bharatkumar Patel ,  Tai Lung Burnnet Or

IPC: G06Q20/32 ,  G06Q20/38

CPC classification number: G06Q20/327 ,  G06Q20/32 ,  G06Q20/322 ,  G06Q20/3829 ,  G06Q20/385 ,  G06Q2220/00 ,  H04L9/0869 ,  H04L63/0428 ,  H04L2209/24

Abstract: Systems and methods provide for communication of transaction data that is formatted according to a transaction type that is support by an access device. First transaction data may be formatted according to a first type of transaction supported by a first access device and second transaction data may be formatted according to a second type of transaction supported by a second access device. The first transaction data may be transmitted over a first wireless communication link to the first access device and the second transaction data may be transmitted to the second access over a second wireless communication link.

Abstract translation: 系统和方法提供根据由访问设备支持的事务类型格式化的事务数据的通信。 第一交易数据可以根据由第一访问设备支持的第一类型的交易进行格式化，并且可以根据由第二访问设备支持的第二类型的交易来格式化第二交易数据。 第一交易数据可以通过第一无线通信链路发送到第一接入设备，并且第二交易数据可以通过第二无线通信链路发送到第二接入。

公开(公告)号：US09387294B2

公开(公告)日：2016-07-12

申请号：US13498620

申请日：2010-09-29

Applicant: David Plumptre ,  Andrew Mark Lindsay ,  Catherine Anne MacDonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones

Inventor： David Plumptre ,  Andrew Mark Lindsay ,  Catherine Anne MacDonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones

IPC: A61M5/00 ,  A61M5/315 ,  A61M5/24 ,  A61M5/31

CPC classification number: A61M5/31585 ,  A61M5/24 ,  A61M5/3146 ,  A61M5/31543 ,  A61M5/31555 ,  A61M5/3157 ,  A61M5/31575 ,  A61M2005/2407 ,  A61M2005/3126 ,  A61M2205/581 ,  A61M2205/582

Abstract: A drug delivery device (4) for dispensing one or more doses of a drug is provided. The device (4) comprises a drive member (1) for driving a piston rod (5) and a dose member (46) for actuating the drive member (1). The piston rod (5) is coupled to the drive member (1) such that a relative translational movement of the drive member (1) and the piston rod (5) is allowed and a relative rotational movement is prevented. The drive member (1) is configured to be driven by the dose member (46) around the longitudinal axis in a first (110) and a second rotational direction (111) opposite to each other. Furthermore, a drug delivery device (4) is provided, wherein the drive member (1) has stable and unstable states and wherein in an unstable state the drive member (1) is biased by biasing means (3) towards a stable state.

Abstract translation: 提供了用于分配一个或多个剂量的药物的药物输送装置（4）。 装置（4）包括用于驱动活塞杆（5）的驱动构件（1）和用于致动驱动构件（1）的剂量构件（46）。 活塞杆（5）联接到驱动构件（1），使得驱动构件（1）和活塞杆（5）的相对平移运动被允许并且防止相对的旋转运动。 驱动构件（1）被配置为在彼此相对的第一（110）和第二旋转方向（111）中围绕纵向轴线由剂量构件（46）驱动。 此外，提供了药物输送装置（4），其中驱动构件（1）具有稳定和不稳定的状态，并且其中在不稳定状态下，驱动构件（1）由偏置装置（3）朝向稳定状态偏置。

公开(公告)号：US09358340B2

公开(公告)日：2016-06-07

申请号：US13496337

申请日：2010-09-29

Applicant: Christopher Jones ,  Robert Veasey ,  Garen Kouyoumjian ,  Catherine Anne MacDonald ,  Michael Jugl ,  Gunther Sendatzki

Inventor： Christopher Jones ,  Robert Veasey ,  Garen Kouyoumjian ,  Catherine Anne MacDonald ,  Michael Jugl ,  Gunther Sendatzki

IPC: A61M5/24 ,  A61M5/31 ,  A61M5/315 ,  A61M5/32 ,  A61M5/34

CPC classification number: A61M5/24 ,  A61M5/3146 ,  A61M5/31555 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/344 ,  A61M5/347 ,  A61M2005/2407 ,  A61M2005/2477 ,  A61M2005/2488 ,  A61M2205/6045 ,  A61M2207/00 ,  Y10T29/49826

Abstract: A method for securing a cartridge (4) in a cartridge holder (3) is provided, the method comprising the steps of inserting the cartridge (4) into the cartridge holder (3), the cartridge holder (3) having a proximal end and a distal end, axially displacing the cartridge (4) in a proximal direction with respect to the cartridge holder (3) from a distal initial position to a proximal end position and securing the cartridge (4) in the end position against displacement in the distal direction with respect to the cartridge holder (3). An assembly for a drug delivery device (1) is provided comprising a cartridge (4), an adjusting member (12, 25, 28, 34) and a cartridge holder (3). The cartridge holder (3) has a distal end and a proximal end. The adjusting member (12, 25, 28, 34) is secured to the cartridge holder (3). The adjusting member (12, 25, 28, 34) holds a distal portion of the cartridge (4) at a distance with respect to a distal portion of the cartridge holder (3).

Abstract translation: 提供了一种用于将盒（4）固定在盒保持器（3）中的方法，所述方法包括以下步骤：将盒（4）插入盒保持器（3），盒保持器（3）具有近端和 一个远端，使药筒（4）相对于药筒保持器（3）的近端方向从远端初始位置轴向移位到近端位置，并将药筒（4）固定在终端位置，防止远端 方向相对于盒保持器（3）。 提供了一种用于药物输送装置（1）的组件，其包括盒（4），调节构件（12,25,28,34）和盒保持器（3）。 药筒保持器（3）具有远端和近端。 调节构件（12,25,28,34）固定在盒保持架（3）上。 调节构件（12,25,28,34）将盒（4）的远端部分相对于盒保持器（3）的远端部分保持一段距离。

公开(公告)号：US09323873B2

公开(公告)日：2016-04-26

申请号：US13330618

申请日：2011-12-19

Applicant: Steven Hodgson ,  Jason Sotiris Polychronopoulos ,  Christopher Jones ,  Zakwan Shaar ,  Muhammed Mutaher Kamal Hashmi ,  Len Theobald ,  Wilfred Barry Hughes

Inventor： Steven Hodgson ,  Jason Sotiris Polychronopoulos ,  Christopher Jones ,  Zakwan Shaar ,  Muhammed Mutaher Kamal Hashmi ,  Len Theobald ,  Wilfred Barry Hughes

IPC: G06F9/45 ,  G06F17/50 ,  G06F11/32 ,  G06F11/36 ,  G06F9/44 ,  G06F11/34

CPC classification number: G06F17/5036 ,  G06F8/20 ,  G06F11/323 ,  G06F11/3457 ,  G06F11/3664 ,  G06F17/5022

Abstract: A method for simulating behavior of first and second interrelated components within a system. The method comprises modelling behavior of said first and second components using first and second functional specifications; simulating behavior of said first and second components in predetermined circumstances by instantiating at least one first entity within a hierarchy of interrelated entities; and instantiating at least one further entity in response to the or each instantiated first entity. The or each further entity is selected by a simulation system on the basis of its hierarchical relationship with the at least one first entity.

Abstract translation: 一种用于模拟系统内第一和第二相关组件的行为的方法。 该方法包括使用第一和第二功能规范来建模所述第一和第二组件的行为; 通过实例化相关实体的层次结构内的至少一个第一实体，在预定的情况下模拟所述第一和第二组件的行为; 以及响应于所述或每个实例化的第一实体来实例化至少一个另外的实体。 基于其与至少一个第一实体的分层关系，模拟系统选择或每个另外的实体。

公开(公告)号：US09138541B2

公开(公告)日：2015-09-22

申请号：US13322347

申请日：2010-05-28

Applicant: David Plumptre ,  Christopher Jones

Inventor： David Plumptre ,  Christopher Jones

IPC: A61M5/31 ,  A61M5/315 ,  A61M5/24

CPC classification number: A61M5/31543 ,  A61M5/24 ,  A61M5/31541 ,  A61M5/31551 ,  A61M5/31558 ,  A61M5/31575 ,  A61M5/31585 ,  A61M2005/2407 ,  A61M2005/2488 ,  A61M2005/2492 ,  A61M2005/3126 ,  A61M2205/581 ,  A61M2205/582

Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing (17) and an inner housing (5) having an external groove (30; 31). The inner housing guides a driver (7, 9) having either a blocking or locking member (11; 11′) disposed inside the driver that can lock a flexible tab (21) to an internal groove during dose delivery in the inner housing such that the driver follows the path of the groove and to advance a spindle to move a cartridge bung. A dial sleeve (3) is disposed between the outer and inner housing and is rotatably engaged with the inner housing.

Abstract translation: 公开了用于药物输送装置的剂量设定机构。 该机构包括外壳（17）和具有外槽（30; 31）的内壳体（5）。 内部壳体引导具有设置在驾驶员内部的阻塞或锁定构件（11; 11'）的驱动器（7,9），其可以在内部壳体中的剂量递送期间将柔性突片（21）锁定到内部凹槽，使得 驾驶员遵循凹槽的路径，并推动主轴移动墨盒塞。 拨号套筒（3）设置在外壳体和内壳体之间并与内壳体可旋转地接合。

公开(公告)号：US09086460B2

公开(公告)日：2015-07-21

申请号：US13148230

申请日：2010-02-04

Applicant: Maria F. Rice ,  Christopher Jones

Inventor： Maria F. Rice ,  Christopher Jones

IPC: G01N27/416 ,  G01R31/36 ,  H01M10/48 ,  H01M10/42 ,  H01M4/58 ,  H01M10/052

CPC classification number: G01R31/3606 ,  H01M4/5825 ,  H01M10/052 ,  H01M10/425 ,  H01M10/48 ,  H01M10/486 ,  Y02T10/7011

Abstract: The invention relates to an object's state or properties being monitored, such as a lithium-iron-phosphate (LFP) or other type of electrical battery containing one or more LFP or other type of electrical battery cell within the battery, and one or more sensors for measuring the state or property of the object, such as the state of charge of the battery cells, by measuring the magnetic susceptibility or other properties, such as the magnetic susceptibility of electrolyte or the electrodes within the battery cells. The state of charge of the battery cells within the battery are monitored by the one or more sensors, which are coupled to electrical circuits.

Abstract translation: 本发明涉及一种被监测物体的状态或特性，例如锂 - 磷酸铁（LFP）或其它类型的电池，该电池在电池内含有一种或多种LFP或其他类型的电池单体，以及一种或多种传感器 用于通过测量磁化率或诸如电池或电池内的电极的磁化率等其他性能来测量物体的状态或性质，例如电池单元的充电状态。 电池内的电池单元的充电状态由耦合到电路的一个或多个传感器来监测。

公开(公告)号：US08939945B2

公开(公告)日：2015-01-27

申请号：US13497769

申请日：2010-09-29

Applicant: Robert Veasey ,  David Plumptre ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

Inventor： Robert Veasey ,  David Plumptre ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

IPC: A61M5/00 ,  A61M5/315 ,  A61M5/24

CPC classification number: A61M5/31511 ,  A61M5/24 ,  A61M5/31505 ,  A61M5/31555 ,  A61M5/3156 ,  A61M5/31585 ,  A61M2005/2407

Abstract: A lead screw (5) with a screw thread (6) is arranged in a body (1) along an axis (4) and coupled to a lead screw nut (7) with a drive feature (8), so that the lead screw is helically rotatable in the lead screw nut. The lead screw and the lead screw nut are provided with stop features (9) interfering with a rotation of the lead screw in the lead screw nut when a force is applied to the lead screw in an axial direction. The lead screw nut has a surface area facing a guide feature (10) of the body. This surface area has a slope (12) varying around the axis. The assembly interacts such that the lead screw nut rotates in one rotational direction when a force is applied to the lead screw in the axial direction.

Abstract translation: 具有螺纹（6）的导螺杆（5）沿着轴线（4）布置在主体（1）中并且与具有驱动特征（8）的丝杠螺母（7）连接，使得导螺杆 可在导螺杆螺母中螺旋转动。 导向螺钉和导螺杆螺母在沿轴向向导螺杆施加力时，设有阻止导螺杆螺母旋转的停止特征（9）。 导螺杆螺母具有面向主体的引导特征（10）的表面区域。 该表面区域具有围绕轴线变化的斜率（12）。 组件相互作用，使得当螺杆沿轴向施加力时，导螺杆螺母在一个旋转方向上旋转。