公开(公告)号：US10993927B2

公开(公告)日：2021-05-04

申请号：US17023635

申请日：2020-09-17

Applicant: CRITITECH, INC.

Inventor： Michael Baltezor ,  Joseph Farthing ,  Jake Sittenauer ,  Jahna Espinosa ,  Samuel Campbell ,  Matthew McClorey ,  Julia K. Fischer ,  Mark D. Williams ,  Gary E. Clapp

IPC: A61K31/337 ,  A61K9/00 ,  A61K9/10 ,  A61K9/14 ,  A61K9/16 ,  A61K9/51 ,  A61J3/02 ,  B01J19/10 ,  B01J19/26 ,  B01J2/04 ,  B01J3/00 ,  B01J4/00 ,  B01D46/24 ,  B01J3/02 ,  B05B1/34 ,  B05B13/02

Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.

公开(公告)号：US10729673B2

公开(公告)日：2020-08-04

申请号：US16776919

申请日：2020-01-30

Applicant: CRITITECH, INC.

Inventor： Michael Baltezor ,  Joseph Farthing ,  Jake Sittenauer ,  Jahna Espinosa ,  Samuel Campbell ,  Matthew McClorey ,  Julia K. Fischer ,  Mark D. Williams ,  Gary E. Clapp

IPC: A61K31/337 ,  A61K9/00 ,  A61K9/10 ,  A61K9/14 ,  A61K9/16 ,  A61K9/51 ,  A61J3/02 ,  B01J19/10 ,  B01J19/26 ,  B01J2/04 ,  B01J3/00 ,  B01J4/00 ,  B01D46/24 ,  B01J3/02 ,  B05B1/34 ,  B05B13/02

Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.