公开(公告)号：US06565745B2

公开(公告)日：2003-05-20

申请号：US09920124

申请日：2001-08-01

Applicant: Delwin D. Hodgin ,  Dale A. Davison

Inventor： Delwin D. Hodgin ,  Dale A. Davison

IPC: B01D1508

CPC classification number: B01D15/22 ,  G01N30/6004 ,  G01N30/6052 ,  G01N30/6091 ,  Y10T29/49604 ,  Y10T436/255

Abstract: To make an inexpensive chromatographic column and perform chromatography with it, column walls and a column end with an inlet port are molded integrally from plastic and a snap-on end is molded integrally with an outlet port from plastic. A filter is placed in one end of the column and the column is filled with packing material up to the second end. A filter is placed on top of the packing and a snap-on end with a molded outlet port is a snapped onto the body with linear motion until an interference fit is formed. As the body and snap-on end are moved together cantilever members formed integrally with the snap on end are bent outwardly by detent members until the detent members are captured by an opening in the cantilever members.

Abstract translation: 为了制造便宜的色谱柱并进行色谱，柱状壁和具有入口的柱端部由塑料一体成型，并且卡扣端与塑料的出口一体地模制。 过滤器放置在塔的一端，柱子填充有直到第二端的填料。 过滤器放置在填料的顶部，具有模制的出口的卡扣端以线性运动卡扣在主体上，直到形成过盈配合。 随着主体和卡扣端部一起移动，与卡扣端部一体形成的悬臂部件通过制动部件向外弯曲，直到止动件被悬臂部件中的开口捕获。

公开(公告)号：US5755559A

公开(公告)日：1998-05-26

申请号：US673177

申请日：1996-06-26

Applicant: Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

Inventor： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

IPC: B01D11/00 ,  B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F04B53/08 ,  F04B53/14 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  G01N35/04 ,  G21F5/015 ,  F04B49/00

CPC classification number: G01N1/34 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/40 ,  G01N30/28 ,  G21F5/015 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02

Abstract: In a piston pump for pumping liquid carbon dioxide at a temperature below 30 degrees Fahrenheit and pressures at least as high as 7500 psi, the volume leaving the pump is determined by measuring only pressure or other parameter related to flow and movement of the plunger. The position of the piston is measured and the resulting displacement is integrated to determine volume of fluid pumped.

Abstract translation: 在用于在低于30华氏度的温度下泵送液体二氧化碳和至少高达7500psi的压力的活塞泵中，通过仅测量与柱塞的流动和运动相关的压力或其它参数来确定离开泵的体积。 测量活塞的位置，并将所得到的位移整合在一起，以确定泵送的流体体积。

公开(公告)号：US08555709B2

公开(公告)日：2013-10-15

申请号：US11980024

申请日：2007-10-30

Applicant: Dale A. Davison ,  Dale L. Meyer ,  Daniel G. Jameson ,  Jack E. Silver ,  Jon L. Curran ,  Ruth A. Pipes

Inventor： Dale A. Davison ,  Dale L. Meyer ,  Daniel G. Jameson ,  Jack E. Silver ,  Jon L. Curran ,  Ruth A. Pipes

IPC: G01N1/28

CPC classification number: G01N30/02 ,  B01D15/10 ,  G01N30/16 ,  G01N2030/0095

Abstract: A liquid chromatographic system includes columns, column mounting fixtures to which the columns are mounted, a detector, a collector, a controller and a plurality of RFIDs. A first RFID communicates with the controller and cooperating RFIDs mounted to other components provide information such as the history of components, parameters and the like. They also receive information from sensors relating to the operation of the liquid chromatograph, store the information and transmit it. Moreover, the RFIDs may substitute for hard wiring in many applications and may enable a central computer to control several liquid chromatographic system.

Abstract translation: 液相色谱系统包括列，柱安装固定装置，柱安装在其上，检测器，收集器，控制器和多个RFID。 第一RFID与控制器通信，并且安装到其他组件的协作RFID​​提供诸如组件的历史，参数等的信息。 他们还从与液相色谱仪操作相关的传感器接收信息，存储信息并进行传输。 此外，RFID可以代替许多应用中的硬布线，并且可以使得中央计算机能够控制多个液相色谱系统。

公开(公告)号：US08246821B2

公开(公告)日：2012-08-21

申请号：US12221510

申请日：2008-08-04

Applicant: Dale A. Davison

Inventor： Dale A. Davison

IPC: B01D15/08

CPC classification number: B01D15/16 ,  G01F23/168 ,  G01N30/32 ,  G01N2030/342

Abstract: A bubbler is positioned within a solvent reservoir of a chromatographic system with its opening near the bottom of the system to measure the pressure of solvent. The bubbler may use air or may use helium or some other gas so that the solvent can be purged of excess air while its level is being monitored by the bubbler. The bubbler provides a depth signal to a microcontroller that records the drop in pressure and projects a low level of pressure at which point solvent should be replenished. The microprocessor may provide a signal to the operator or terminate operation or automatically replenish solvent depending upon the program.

Abstract translation: 起泡器位于色谱系统的溶剂容器内，其开口靠近系统的底部以测量溶剂的压力。 起泡器可以使用空气或者可以使用氦气或一些其它气体，使得溶剂可被吹扫过量的空气，同时其水平被起泡器监测。 起泡器向记录压力下降的微控制器提供深度信号，并投入低水平的压力，在哪一点溶剂应该被补充。 微处理器可以向操作者提供信号或者终止操作或根据程序自动补充溶剂。

公开(公告)号：US20090166294A1

公开(公告)日：2009-07-02

申请号：US12348305

申请日：2009-01-04

Applicant: Dale A. Davison ,  Ruth A. Pipes ,  Jack E. Silver

Inventor： Dale A. Davison ,  Ruth A. Pipes ,  Jack E. Silver

IPC: B01D15/08

CPC classification number: B01D15/10 ,  B01D15/16 ,  B01J20/28019 ,  B01J20/283 ,  G01N30/16 ,  G01N35/00871 ,  G01N2030/0095

Abstract: Sample is applied to a chromatographic column containing shape stabilized packing and the liquid phase is pumped through the shape stabilized packing at a rate of flow greater than the standard rate of flow to obtain at least one of a target resolution and target time of run. Because of the improved resolution provided by the shape stabilized packing at higher rates of flow of solvent, the chromatographer can either obtain better resolution with a standard gradient or shorten the time of the run and reduce the amount of solvent needed by increasing the slope of the gradient.

Abstract translation: 将样品应用于含有形状稳定的填料的色谱柱，并且液相以大于标准流速的流速泵送通过形状稳定的填料，以获得目标分辨率和目标运行时间中的至少一个。 由于在更高的溶剂流速下由形状稳定的填料提供的改进的分辨率，色谱仪可以以标准梯度获得更好的分辨率或缩短运行时间，并通过增加斜率的斜率来减少所需的溶剂量 梯度。

公开(公告)号：US07419598B2

公开(公告)日：2008-09-02

申请号：US11074880

申请日：2005-03-08

Applicant: Dale A. Davison

Inventor： Dale A. Davison

IPC: B01D15/08

CPC classification number: B01D15/16 ,  G01F23/168 ,  G01N30/32 ,  G01N2030/342

Abstract: A bubbler is positioned within a solvent reservoir of a chromatographic system with its opening near the bottom of the system to measure the pressure of solvent. The bubbler may use air or may use helium or some other gas so that the solvent can be purged of excess air while its level is being monitored by the bubbler. The bubbler provides a depth signal to a microcontroller that records the drop in pressure and projects a low level of pressure at which point solvent should be replenished. The microprocessor may provide a signal to the operator or terminate operation or automatically replenish solvent depending upon the program.

Abstract translation: 起泡器位于色谱系统的溶剂容器内，其开口靠近系统的底部以测量溶剂的压力。 起泡器可以使用空气或者可以使用氦气或一些其它气体，使得溶剂可被吹扫过量的空气，同时其水平被起泡器监测。 起泡器向记录压力下降的微控制器提供深度信号，并投入低水平的压力，在哪一点溶剂应该被补充。 微处理器可以向操作者提供信号或者终止操作或根据程序自动补充溶剂。

公开(公告)号：US20080183401A1

公开(公告)日：2008-07-31

申请号：US11699169

申请日：2007-01-29

Applicant: Dale A. Davison ,  Dale L. Meyer ,  Daniel G. Jameson ,  Jack E. Silver ,  Jon L. Curran ,  Ruth A. Pipes

Inventor： Dale A. Davison ,  Dale L. Meyer ,  Daniel G. Jameson ,  Jack E. Silver ,  Jon L. Curran ,  Ruth A. Pipes

IPC: G01N31/00 ,  G05B21/00

CPC classification number: G01N30/02 ,  B01D15/10 ,  G01N30/16 ,  G01N2030/0095

Abstract: A liquid chromatographic system includes columns, column mounting fixtures to which the columns are mounted, a detector, a collector, a controller and a plurality of RFIDs. A first RFID communicates with the controller and cooperating RFIDs mounted to other components provide information such as the history of components, parameters and the like. They also receive information from sensors relating to the operation of the liquid chromatograph, store the information and transmit it. Moreover, the RFIDs may substitute for hard wiring in many applications and may enable a central computer to control several liquid chromatographic systems.

Abstract translation: 液相色谱系统包括列，柱安装固定装置，柱安装在其上，检测器，收集器，控制器和多个RFID。 第一RFID与控制器通信，并且安装到其他组件的协作RFID​​提供诸如组件的历史，参数等的信息。 他们还从与液相色谱仪操作相关的传感器接收信息，存储信息并进行传输。 此外，RFID可以在许多应用中代替硬布线，并且可以使得中央计算机能够控制多个液相色谱系统。

公开(公告)号：US20080183333A1

公开(公告)日：2008-07-31

申请号：US11980131

申请日：2007-10-30

Applicant: Dale A. Davison ,  Dale L. Meyer ,  Daniel G. Jameson ,  Jack E. Silver ,  Jon L. Curran ,  Ruth A. Pipes

Inventor： Dale A. Davison ,  Dale L. Meyer ,  Daniel G. Jameson ,  Jack E. Silver ,  Jon L. Curran ,  Ruth A. Pipes

IPC: G05B15/00

CPC classification number: G01N30/02 ,  B01D15/10 ,  G01N30/16 ,  G01N2030/0095

Abstract: A liquid chromatographic system includes columns, column mounting fixtures to which the columns are mounted, a detector, a fraction collection system, a controller and a plurality of RFIDs. A first RFID communicates with the controller and cooperating RFIDs mounted to other components including the fraction collector to provide information such as the history of components, parameters and the like useful in maintaining inventory control and managing the system. They also receive information from sensors relating to the operation of the fraction collector including the location of sample containers.

Abstract translation: 液相色谱系统包括柱，柱安装固定装置，柱安装在其上，检测器，馏分收集系统，控制器和多个RFID。 第一RFID与控制器进行通信，并且配合RFID安装到包括分数收集器的其它部件的RFID，以提供用于维护库存控制和管理系统的组件历史，参数等信息。 它们还从包括样品容器位置的馏分收集器的操作的传感器接收信息。

公开(公告)号：US06427526B1

公开(公告)日：2002-08-06

申请号：US09794772

申请日：2001-02-27

Applicant: Dale A. Davison ,  Scott L. Blakley

Inventor： Dale A. Davison ,  Scott L. Blakley

IPC: G01N1300

CPC classification number: G01N35/1097 ,  B01D15/12 ,  B01D15/166 ,  B01D15/247 ,  G01N1/38 ,  G01N30/32 ,  G01N30/466 ,  G01N2001/383 ,  G01N2030/324 ,  G01N2030/326

Abstract: To economically perform preparatory chromatography, a plurality of pumps each having a corresponding one of a plurality of pistons and a corresponding one of a plurality of cylinders are driven by one motor to draw and pump solvent simultaneously into corresponding columns. To form a gradient the pumps are connected to two-way valves that are connected alternately to a first solvent and a second solvent, whereby the time said valve is in a first position controls the amount of solvent drawn from said first reservoir into said pumps and the amount of time in said second position controls the amount of said second solvent drawn into said pumps and the solvent is mixed in the pumping systems. The detectors are photodiodes mounted to light guides in the flow cells that generate signals related to light absorbance and communicate with a controller, whereby said controller receives signals indicating solute between the light guides and causes collection of solute.

Abstract translation: 为了经济地进行准备色谱，每个具有多个活塞中的相应一个活塞和多个气缸中的相应一个的多个泵由一个电动机驱动，以将溶剂同时泵送到相应的列中。 为了形成梯度，泵连接到交替地连接到第一溶剂和第二溶剂的双向阀，由此所述阀处于第一位置的时间控制从所述第一储存器抽入所述泵中的溶剂的量， 所述第二位置中的时间量控制吸入所述泵中的所述第二溶剂的量并且所述溶剂在所述泵送系统中混合。 检测器是安装在流动池中的光导的光电二极管，其产生与吸光度相关的信号并与控制器通信，由此所述控制器接收指示光导之间的溶质并引起溶质的收集的信号。

公开(公告)号：US5844147A

公开(公告)日：1998-12-01

申请号：US814950

申请日：1997-03-10

Applicant: Robert R. Fiedler ,  Dale A. Davison

Inventor： Robert R. Fiedler ,  Dale A. Davison

IPC: G01N1/14 ,  G01N1/34 ,  G01N1/40 ,  G01N33/18 ,  G01N1/18

CPC classification number: G01N1/405 ,  G01N1/14 ,  G01N1/40 ,  G01N33/18

Abstract: A method and apparatus for water sampling utilizing on-site solid phase extraction that permits high sample flow rates and eliminates the requirement for sample storage. Samples are collected at a relatively high flow rate and then temporarily stored under pressure before passing through a solid phase extraction device at a slower rate commensurate with the flow rate tolerance of the device. Each sample quantity is also automatically measured, eliminating the requirement for sample storage and subsequent manual quantity measurement and/or transportation to a laboratory.

Abstract translation: 一种利用现场固相萃取进行水采样的方法和装置，其允许高样品流速并消除对样品储存的要求。 以相对高的流速收集样品，然后在压力下临时储存，然后通过固相萃取装置，其速度与装置的流量容许度相当。 每个样品量也自动测量，不需要样品储存和随后的手动量测量和/或运送到实验室。