Immortalized, homozygous stat1-deficient mammalian cell lines and their uses
    11.
    发明授权
    Immortalized, homozygous stat1-deficient mammalian cell lines and their uses 失效
    不育的,纯合的stat1缺陷的哺乳动物细胞系及其用途

    公开(公告)号:US06740519B1

    公开(公告)日:2004-05-25

    申请号:US08962740

    申请日:1997-11-03

    CPC classification number: C12N7/00 C12N2510/04 C12N2760/16151

    Abstract: The present invention is directed to immortalized STAT1-deficient mammalian cell lines. STAT1 is a signal transducer and activator of transcription that becomes phosphorylated when cells are treated with type I or type II interferons and leads to induction of specific gene expression, resulting in establishment of the antiviral state and the other known biological responses to interferons, including the inhibition of cell proliferation. Cells which lack this gene product are useful for producing high titers of viral stocks, for producing recombinant viral vectors, for testing samples, especially clinical samples for the presence of virus and for screening candidate compounds or drugs for anti-viral activity.

    Abstract translation: 本发明涉及永生化的STAT1缺陷哺乳动物细胞系。 STAT1是当I型或II型干扰素处理细胞并且导致特异性基因表达的诱导时,转录的信号转导和转录激活物变得磷酸化,导致抗病毒状态的建立和对干扰素的其它已知的生物学应答,包括 抑制细胞增殖。 缺乏该基因产物的细胞可用于产生高滴度的病毒种群,用于产生重组病毒载体,用于测试样品,特别是用于病毒存在的临床样品和筛选候选化合物或药物用于抗病毒活性。

    Market-based Fact Verification Media System and Method

    公开(公告)号:US20220351213A1

    公开(公告)日:2022-11-03

    申请号:US17574541

    申请日:2022-01-12

    Applicant: David Levy

    Inventor: David Levy

    Abstract: The system and methods described herein provide a way for writers and publishers to stand behind individual and combined facts in their work by offering a bounty to a person who can supersede their own data in support of the fact's accuracy with better data, as measured by a pre-established fact evaluation guideline. Once sufficiently vetted by this system, facts are added to an apolitical certified fact database. Facts in the certified fact database also have a bounty upon their accuracy, however financial responsibility for the bounty is transferred to the system. Subscribers to the system may then download and use fact contained within the certified fact database to enhance their own work, while benefiting from the enhanced readership, interest and. trustworthiness provided by virtue of the bounty.

    BI-SPRING SURGICAL HAMMER IMPACT TOOLS

    公开(公告)号:US20220273317A1

    公开(公告)日:2022-09-01

    申请号:US17678807

    申请日:2022-02-23

    Applicant: David Levy

    Inventor: David Levy

    Abstract: Disclosed herein are bi-spring surgical hammer impact tools and methods of use thereof. The bi-spring surgical hammer impact tools can include an elongated drive rod disposed in the housing and including an impact flange in a mid-region thereof. A tool implement can be mounted to a first end of the elongated drive rod. An impact shuttle can be mounted on the elongated drive rod and can include first and second impact surfaces opposing opposite faces of the impact flange. A plurality of annular teeth can be defined by an exterior surface of the impact shuttle. First and second springs can be disposed against opposite ends of the impact shuttle. A partial tooth pinion attached to a drive shaft and movable for engagement with the plurality of annular teeth of the impact shuttle can be included.

    Fishing rig storage device and system

    公开(公告)号:US10701921B2

    公开(公告)日:2020-07-07

    申请号:US15806683

    申请日:2017-11-08

    Abstract: A fishing rig storage device that is removably insertable into a receiving slot incorporated in at least one of a dividing wall or an interior surface of a tackle container is illustrated and described. The fishing rig storage device includes a mounting tab having quartered sections and a plurality of notches formed along a perimeter. Each quartered section includes at least one of the plurality of notches. A fishing rig having a hook assembly, a line, and a tail is secured to the mounting tab by securing the hook assembly to a first notch, selectively wrapping the line around the plurality of notches, and securing the tail to a slit extending from the perimeter. The line is preferably arranged around the mounting tab to minimize catching or snagging of the line on the hook assembly when the line is unwrapped from the mounting tab.

    METHOD AND APPARATUS FOR CONTROLLING IRRIGATION
    16.
    发明申请
    METHOD AND APPARATUS FOR CONTROLLING IRRIGATION 有权
    控制灌溉的方法和装置

    公开(公告)号:US20120203383A1

    公开(公告)日:2012-08-09

    申请号:US13291027

    申请日:2011-11-07

    Abstract: The invention comprises devices and methods for providing operational power to a solar-powered irrigation control system. In one aspect, a method includes producing electrical energy from light, storing the electrical energy in a capacitive module, and operating an irrigation controller using the stored electrical energy independent of another power source. In another aspect, a device includes a control system comprising a computer having a programmed irrigation schedule which operates at least one irrigation device, a photovoltaic power module, and a capacitive module connected to said photovoltaic power module to store the electrical energy provided by the photovoltaic power module, where the capacitive module provides power for the control system to operate the at least one irrigation device independent of another power source.

    Abstract translation: 本发明包括用于向太阳能灌溉控制系统提供操作功率的装置和方法。 一方面,一种方法包括从光产生电能,将电能存储在电容性模块中,以及使用所存储的电能独立于另一电源来操作冲洗控制器。 在另一方面,一种设备包括控制系统,其包括具有编程灌溉计划的计算机,该计划操作至少一个冲洗装置,光伏功率模块和连接到所述光伏功率模块的电容模块,以存储由光伏提供的电能 功率模块,其中电容性模块为控制系统提供功率,以独立于另一个电源来操作至少一个冲洗装置。

    System to determine connector leaks during testing
    17.
    发明授权
    System to determine connector leaks during testing 失效
    在测试期间确定连接器泄漏的系统

    公开(公告)号:US08078413B2

    公开(公告)日:2011-12-13

    申请号:US12432677

    申请日:2009-04-29

    Applicant: David Levy

    Inventor: David Levy

    CPC classification number: G01M3/2853 G01L19/0092 G01L19/12

    Abstract: A system for evaluating the leak tightness of a connector, or multiple connectors. The system uses an administrative server having a library of pressure and temperature information on various connectors, as well as the ability to report pressure and temperature data to a network as uncorrected and corrected responses. The system uses a data logger for recording pressure and temperature readings and also reporting corrected and uncorrected responses using one or more equations to shorten the test time by at least 50 percent or to about 5 minutes or less. The system uses a test pump for applying pressure to a connector to generate a corrected pressure which indicates leaks when the corrected pressure changes.

    Abstract translation: 用于评估连接器或多个连接器的密封性的系统。 该系统使用具有各种连接器上的压力和温度信息库的管理服务器,以及将压力和温度数据报告给网络的能力,作为未校正和纠正的响应。 该系统使用数据记录器记录压力和温度读数,并且还使用一个或多个方程来报告校正和未校正的响应,以将测试时间缩短至少50%或约5分钟或更短。 系统使用测试泵向连接器施加压力,以产生校正的压力,该压力指示当校正的压力变化时的泄漏。

    METHOD OF ENERGIZING A CONNECTOR
    18.
    发明申请
    METHOD OF ENERGIZING A CONNECTOR 有权
    加强连接器的方法

    公开(公告)号:US20100140931A1

    公开(公告)日:2010-06-10

    申请号:US12706783

    申请日:2010-02-17

    Applicant: David Levy

    Inventor: David Levy

    Abstract: A method of energizing a high pressure tube connector for a well comprising a tube; a first connector assembly comprising: a female profile disposed over the tube and a first ferrule disposed over the tube adjacent the female profile; a second connector assembly comprising: an inverted jam nut disposed over the tube and a second ferrule disposed over the tube adjacent the inverted jam nut, wherein the second ferrule extends along the tube in a direction opposite the first ferrule; a nipple comprising a test port, wherein the nipple is disposed over the tube between the first ferrule and the second ferrule; a primary seal formed by compressing the first ferrule into the female profile using a pressure from the test port; and a secondary seal formed by compressing the second ferrule into the inverted jam nut using the pressure from the test port.

    Abstract translation: 一种为包括管的井的高压管连接器通电的方法; 第一连接器组件,其包括:设置在所述管上方的阴型轮廓,以及设置在所述管上邻近所述母型材的第一套圈; 第二连接器组件,包括:设置在所述管上方的倒置的止动螺母和邻近所述倒置的止动螺母设置在所述管上的第二套圈,其中所述第二套圈沿着所述管沿与所述第一套圈相反的方向延伸; 包括测试端口的接头,其中所述接头设置在所述管之间的所述第一套圈和所述第二套圈之间; 使用来自测试端口的压力将第一套圈压缩到阴型轮中形成的主密封; 以及通过使用来自测试端口的压力将第二套圈压缩成倒置的止动螺母而形成的二次密封。

    System and method for controlling speed of a moving vehicle
    19.
    发明授权
    System and method for controlling speed of a moving vehicle 有权
    用于控制移动车辆速度的系统和方法

    公开(公告)号:US07711468B1

    公开(公告)日:2010-05-04

    申请号:US11970069

    申请日:2008-01-07

    Applicant: David Levy

    Inventor: David Levy

    CPC classification number: B60W30/143 B60W2550/22 B60W2550/402

    Abstract: A system, a method and device for controlling speed of a moving vehicle, using portable and repositionable global positioning devices, speed limit processors, and a database of legal vehicle speed limits is in communication with the speed limit processor. Computer instructions instruct the speed limit processor to match the current location of the moving vehicle with a legal vehicle speed limit for a defined location using the database. The speed limit processor communicates the legal vehicle speed limit to the vehicle processor to control the speed of the moving vehicle.

    Abstract translation: 使用便携式和可重新定位的全球定位装置,速度限制处理器和合法车辆速度限制的数据库来控制移动车辆的速度的系统,方法和装置与速度限制处理器通信。 计算机指令指示速度限制处理器将移动车辆的当前位置与使用数据库的定义位置的合法车辆速度限制相匹配。 速度限制处理器将合法的车速限制通知车辆处理器以控制移动车辆的速度。

    Privacy and Security Method and System for a World-Wide-Web Site
    20.
    发明申请
    Privacy and Security Method and System for a World-Wide-Web Site 有权
    全球网站的隐私和安全方法和系统

    公开(公告)号:US20090171982A1

    公开(公告)日:2009-07-02

    申请号:US12397603

    申请日:2009-03-04

    Abstract: Personal information of users is used to customize the browsing experiences of the users on a World-Wide-Web site. To ensure privacy of the users' personal information, each user is assigned a unique Universal Anonymous Identifier (UAI). The UAI is generated by a trusted third party and provided to the Web site operator. The Web site operator then indexes the users' personal information by UAI. Only the user has the ability to correlate his/her true identity with his/her personal information.

    Abstract translation: 用户的个人信息用于在万维网站点上定制用户的浏览体验。 为了确保用户个人信息的隐私,每个用户都被分配一个唯一的通用匿名标识符(UAI)。 UAI由可信赖的第三方生成并提供给网站运营商。 网站运营商然后用UAI索引用户的个人信息。 只有用户有能力将他/她的真实身份与他/她的个人信息相关联。

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