公开(公告)号：US09817011B2

公开(公告)日：2017-11-14

申请号：US15430726

申请日：2017-02-13

Applicant: GEN-PROBE INCORPORATED

Inventor： David Buse ,  Byron J. Knight

IPC: G01N35/10 ,  G01N35/02 ,  G01N35/00 ,  B65D1/36 ,  B65D17/50 ,  B01L3/00

CPC classification number: B01L3/5085 ,  B01L3/502 ,  B01L3/5082 ,  B01L3/50825 ,  B01L3/50853 ,  B01L3/50855 ,  B01L3/523 ,  B01L3/527 ,  B01L2200/02 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/0668 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/044 ,  B01L2300/046 ,  B01L2300/047 ,  B01L2300/048 ,  B01L2300/0609 ,  B01L2300/0829 ,  B01L2300/0832 ,  B01L2300/0838 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/12 ,  B01L2400/0406 ,  B65B69/00 ,  B65D1/0207 ,  B65D1/34 ,  B65D1/36 ,  B65D17/50 ,  B65D39/0017 ,  B65D39/0029 ,  B65D2539/003 ,  C12Q1/686 ,  G01N30/6091 ,  G01N35/0099 ,  G01N35/026 ,  G01N35/10 ,  G01N35/1002 ,  G01N35/1079 ,  G01N2035/00287 ,  Y10T436/11

Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.

公开(公告)号：US09724948B2

公开(公告)日：2017-08-08

申请号：US14919467

申请日：2015-10-21

Applicant: GEN-PROBE INCORPORATED

Inventor： Rolf Silbert ,  Robert Rosati ,  David Buse ,  Olev Tammer ,  Matthias Merten

IPC: B41J29/38 ,  B41J2/32 ,  B41J3/407 ,  G01N35/00 ,  G01N35/10

CPC classification number: B41J29/38 ,  B41J2/32 ,  B41J3/4073 ,  B41J3/4075 ,  G01N35/00732 ,  G01N2035/00861 ,  G01N2035/1032

Abstract: A printing module configured to print a label on a curved surface of an article includes an expandable printing mechanism configured to be expanded to an open configuration for receiving the article or contracted to a closed configuration placing the curved surface in an operative position with respect to a print head and an article moving assembly configured to grasp and hold the article and effect relative movement between the curved surface and the print head. The printing mechanism includes contact elements, such as rollers, that contact or otherwise engage the article when the printing mechanism is in the closed configuration and maintain the curved surface in the operative position with respect to the print head during relative movement between the curved surface and the print head.

公开(公告)号：US11794189B2

公开(公告)日：2023-10-24

申请号：US17210040

申请日：2021-03-23

Applicant: Gen-Probe Incorporated

Inventor： David Buse ,  Byron J. Knight

IPC: B01L3/00 ,  B65D51/00

CPC classification number: B01L3/523 ,  B65D51/002 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0858 ,  B01L2300/123

Abstract: A container includes a base with a top wall, a vessel depending from a top wall aperture in the top wall, a fluid retainer projecting above the top wall and surrounding the top wall aperture, and a skirt surrounding the vessel and including opposed grooves for gripping the container. A lid is disposed on a top end of the base and includes a cover wall with a lid aperture generally aligned with the top wall aperture of the base. A septum is disposed between the top wall of the base and the cover wall with a portion of the septum disposed between the lid aperture and the top wall aperture. Fluid retainer/return structure is configured to prevent fluid deposited on the septum from dripping off the container and to allow at least a portion of the fluid deposited on the septum to run off the septum and into the vessel.

公开(公告)号：US20210079452A1

公开(公告)日：2021-03-18

申请号：US17033395

申请日：2020-09-25

Applicant: Gen-Probe Incorporated

Inventor： David Buse ,  Norbert D. Hagen ,  David Opalsky ,  Bruce Richardson ,  Anita Prasad ,  Tyler Moore ,  Byron J. Knight

IPC: C12Q1/6806 ,  G01N35/04 ,  B01L3/00 ,  B01L7/00 ,  C12Q1/686

Abstract: A receptacle cap includes a probe recess configured to receive a probe inserted therein to thereby frictionally secure the receptacle cap to the probe, and a closed lower end of the receptacle is insertable into an open end of a reaction receptacle to close the reaction receptacle. The receptacle cap and the reaction receptacle include interlocking features for securing the receptacle cap to the reaction receptacle.

公开(公告)号：US10563251B2

公开(公告)日：2020-02-18

申请号：US15951818

申请日：2018-04-12

Applicant: Gen-Probe Incorporated

Inventor： David Buse ,  David Howard Combs ,  Norbert D. Hagen ,  David Opalsky ,  Bruce Richardson ,  Anita Prasad ,  Keith Moravick ,  Tyler Moore

IPC: C12Q1/686 ,  B01L7/00 ,  G01N21/64 ,  B01L9/06

Abstract: First and second sets of receptacles containing reagents for first and second amplification reactions, respectively, are placed in first and second receptacle holders, each associated with a thermal element. The receptacles are subjected to different first and second incubation processes resulting in the first and second amplification reactions in each of the first and second sets of receptacles that contain a first or a second target nucleic acid, respectively. The presence or absence of the first or second target nucleic acid, if any, is determined for each receptacle of the first and second sets of receptacles.

公开(公告)号：US10464360B2

公开(公告)日：2019-11-05

申请号：US15669378

申请日：2017-08-04

Applicant: GEN-PROBE INCORPORATED

Inventor： Rolf Silbert ,  Robert Rosati ,  David Buse ,  Olev Tammer ,  Matthias Merten

IPC: B41J29/38 ,  B41J2/32 ,  B41J3/407 ,  G01N35/00 ,  G01N35/10

Abstract: A printing module configured to print a label on a curved surface of an article includes an expandable printing mechanism configured to be expanded to an open configuration for receiving the article or contracted to a closed configuration placing the curved surface in an operative position with respect to a print head and an article moving assembly configured to grasp and hold the article and effect relative movement between the curved surface and the print head. The printing mechanism includes contact elements, such as rollers, that contact or otherwise engage the article when the printing mechanism is in the closed configuration and maintain the curved surface in the operative position with respect to the print head during relative movement between the curved surface and the print head.

公开(公告)号：US20180230517A1

公开(公告)日：2018-08-16

申请号：US15951818

申请日：2018-04-12

Applicant: Gen-Probe Incorporated

Inventor： David Buse ,  David Howard Combs ,  Norbert D. Hagen ,  David Opalsky ,  Bruce Richardson ,  Anita Prasad ,  Keith Moravick ,  Tyler Moore

IPC: C12Q1/686 ,  B01L7/00

Abstract: First and second sets of receptacles containing reagents for first and second amplification reactions, respectively, are placed in first and second receptacle holders, each associated with a thermal element. The receptacles are subjected to different first and second incubation processes resulting in the first and second amplification reactions in each of the first and second sets of receptacles that contain a first or a second target nucleic acid, respectively. The presence or absence of the first or second target nucleic acid, if any, is determined for each receptacle of the first and second sets of receptacles.

公开(公告)号：US09718059B2

公开(公告)日：2017-08-01

申请号：US14210105

申请日：2014-03-13

Applicant: GEN-PROBE INCORPORATED

Inventor： David Buse ,  Byron J. Knight ,  Julian Groeli

IPC: B01L3/00 ,  B65B69/00 ,  B65D1/02 ,  B65D1/34 ,  B65D39/00 ,  C12Q1/68 ,  G01N35/02 ,  G01N35/10 ,  G01N30/60 ,  G01N35/00

CPC classification number: B01L3/5085 ,  B01L3/502 ,  B01L3/5082 ,  B01L3/50825 ,  B01L3/50853 ,  B01L3/50855 ,  B01L3/523 ,  B01L3/527 ,  B01L2200/02 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/0668 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/044 ,  B01L2300/046 ,  B01L2300/047 ,  B01L2300/048 ,  B01L2300/0609 ,  B01L2300/0829 ,  B01L2300/0832 ,  B01L2300/0838 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/12 ,  B01L2400/0406 ,  B65B69/00 ,  B65D1/0207 ,  B65D1/34 ,  B65D1/36 ,  B65D17/50 ,  B65D39/0017 ,  B65D39/0029 ,  B65D2539/003 ,  C12Q1/686 ,  G01N30/6091 ,  G01N35/0099 ,  G01N35/026 ,  G01N35/10 ,  G01N35/1002 ,  G01N35/1079 ,  G01N2035/00287 ,  Y10T436/11

Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.

公开(公告)号：US11945239B2

公开(公告)日：2024-04-02

申请号：US17396525

申请日：2021-08-06

Applicant: GEN-PROBE INCORPORATED

Inventor： Rolf Silbert ,  Robert J. Rosati ,  David Buse ,  Olev Tammer ,  Matthias Merten

IPC: B41J29/38 ,  B41J2/32 ,  B41J3/407 ,  G01N35/00 ,  G01N35/10

CPC classification number: B41J29/38 ,  B41J2/32 ,  B41J3/4073 ,  B41J3/4075 ,  G01N35/00732 ,  G01N2035/00861 ,  G01N2035/1032

Abstract: A method for controlling a printing process by which a print head prints an image onto predetermined printable area of a label.

公开(公告)号：US11692220B2

公开(公告)日：2023-07-04

申请号：US17027433

申请日：2020-09-21

Applicant: Gen-Probe Incorporated

Inventor： David Buse ,  David Howard Combs ,  Norbert D. Hagen ,  David Opalsky ,  Bruce Richardson ,  Anita Prasad ,  Keith Moravick ,  Tyler Moore ,  Byron J. Knight

IPC: C12Q1/686 ,  B01L7/00 ,  G01N21/64 ,  B01L9/06

CPC classification number: C12Q1/686 ,  B01L7/52 ,  G01N21/6452 ,  B01L9/06 ,  B01L2200/141 ,  B01L2200/142 ,  B01L2300/042 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/0851 ,  B01L2300/1822 ,  G01N2021/6482 ,  G01N2021/6484

Abstract: An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder with multiple receptacle wells. Each well has a through-hole extending from an inner surface of the well to an outer surface of the holder. A cover is rotatable between an open position and a closed position relative to the holder and is configured to exert a force onto any receptacles in the wells when the cover is in the closed position. The apparatus includes multiple optical fibers, and each of the optical fibers provides optical communication between one of the wells and an excitation signal source and/or an emission signal detector. A thermal element is positioned between a thermally-conductive support and the receptacle holder.