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Patent Agency Ranking
11.发明申请公开(公告)号：US20150297821A1
公开(公告)日：2015-10-22
申请号：US14642538
申请日：2015-03-09
Applicant: ImMutriX Therapeutics, Inc.
Inventor： Carol A. Rae , Jan Simoni , Grace Simoni , John F. Moeller
IPC: A61M1/36
CPC classification number: A61M1/3679 , A61M5/165 , A61M2202/0021 , A61M2202/0042 , A61M2202/0413 , A61M2202/206 , B01J20/20 , B01J47/02
Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
Abstract translation: 一种包括从受试者获得体液的方法; 使身体液体与包含合成碳颗粒（SCP）的吸附材料接触以产生具有疾病介质（y）水平的第一滤液; 使第一滤液与包含SCP和阴离子交换树脂的吸附剂材料接触，其中SCP与阴离子交换树脂的比例为约0.1:100至100:0.1，以产生第二滤液; 使第二滤液与包含SCP和阳离子交换树脂的吸附剂材料接触，其中SCP与阳离子交换树脂的比例为约1:100以产生第三滤液; 并向所述受试者施用所述第三滤液。
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公开(公告)号：US12296085B2
公开(公告)日：2025-05-13
申请号：US16088785
申请日：2017-03-31
Applicant: Immutrix Therapeutics, Inc.
Inventor： Carol A. Rae , Jan Simoni , John F. Moeller
Abstract: A three-component composition for use in the treatment of preeclampsia and related disorders wherein a first component comprises a bimodal synthetic carbon particle mixture; a second component comprises a resin bead with at least one affinity ligand directed toward syncytiotrophoblast-derived factor sEndoglin and a third component comprises a resin bead with at least one affinity ligand directed toward syncytiotrophoblast-derived factor soluble Fms-like tyrosine kinase-1.
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13.发明公开公开(公告)号：US20240165314A1
公开(公告)日：2024-05-23
申请号：US18396143
申请日：2023-12-26
Applicant: Immutrix Therapeutics, Inc.
Inventor： Carol A. Rae , Jan Simoni , Grace Simoni , John F. Moeller
CPC classification number: A61M1/3679 , A61M1/0281 , A61M1/14 , A61M1/3687 , B01J20/20 , B01J47/02
Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
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14.发明授权公开(公告)号：US10773011B2
公开(公告)日：2020-09-15
申请号：US15584796
申请日：2017-05-02
Applicant: ImMutriX Therapeutics, Inc.
Inventor： Carol A. Rae , Jan Simoni , Grace Simoni , John F. Moeller
Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
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15.发明申请公开(公告)号：US20170232183A1
公开(公告)日：2017-08-17
申请号：US15584796
申请日：2017-05-02
Applicant: ImMutriX Therapeutics, Inc.
Inventor： Carol A. Rae , Jan Simoni , Grace Simoni , John F. Moeller
CPC classification number: A61M1/3679 , A61M5/165 , A61M2202/0021 , A61M2202/0042 , A61M2202/0413 , A61M2202/206 , B01J20/20 , B01J47/02
Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
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