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公开(公告)号：US20100312574A1
公开(公告)日：2010-12-09
申请号：US12735729
申请日：2009-02-13
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
CPC classification number: G01N35/00069 , G06Q50/22 , Y02A90/22
Abstract: Provided is a bio-disc reading apparatus for reading information including product authentication of a bio-disc and assay site of a bio-disc, and an assay method using same.
Abstract translation: 提供了一种用于读取包括生物盘的生物盘和测定位点的产品认证的信息的生物盘读取装置以及使用其的测定方法。
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公开(公告)号：US20100234237A1
公开(公告)日：2010-09-16
申请号：US11919567
申请日：2006-05-02
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
CPC classification number: C12Q1/686 , B01L3/50273 , B01L3/502738 , B01L2200/10 , B01L2200/143 , B01L2300/0806 , B01L2400/0409 , B01L2400/043 , B01L2400/0633 , F16K99/0001
Abstract: A bio-disc device including new valve control means and fluid movement system, a bio-driver apparatus in which a controller disc including a controller for the bio-disc is installed, and an assay method using the same, which are suitable for labs-on-a-chips for various diagnostic assays, nucleic acid hybridization assays, and immunoassays, are provided. The bio-driver apparatus is compatible with general optical discs, including audio CDs, CD-Rs, game CDs, DVDs, etc., and the assay method is compatible with general optical disc drivers, including CD-ROMs, DVD players, etc. Thus, the bio-driver apparatus and the assay method offer and economical and convenient alternative to existing products. In addition, the bio-driver apparatus can be readily and easily applied in connection with a computer for remote diagnosis via the Internet.
Abstract translation: 一种包括新的阀控制装置和流体移动系统的生物盘装置，其中安装有包括用于生物盘的控制器的控制器盘的生物驱动装置，以及使用该控制盘的适用于实验室的测定方法， 提供用于各种诊断测定的芯片，核酸杂交测定和免疫测定。 该生物驱动装置与通用光盘兼容，包括音频CD，CD-R，游戏CD，DVD等，并且该测定方法与通常的光盘驱动器（包括CD-ROM，DVD播放器等）兼容。 因此，生物驱动装置和测定方法为现有产品提供了经济和方便的替代方案。 此外，生物驱动装置可以容易地和容易地应用于计算机，以经由因特网进行远程诊断。
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公开(公告)号：US20100144021A1
公开(公告)日：2010-06-10
申请号：US12585504
申请日：2009-09-16
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
IPC: C12M1/34
CPC classification number: B82Y30/00 , C12Q1/6823 , Y02A90/22 , Y02A90/26 , C12Q2533/101 , C12Q2525/131 , C12Q2521/301 , C12Q2565/625
Abstract: A cleavable signal element applicable to quantitative and qualitative assay devices, using a cleavable technique specifically responsive to a complementary double strand or single strand of nucleic acids, and a nucleic acid hybridization assay method and device using the cleavable signal element are provided. Using the cleavable technique responsive to the complementary double strand or single strand of nucleic acids, detection sensitivity to a target nucleic acid can be increased, and diagnosis and detection reliability can be improved twice through in-situ determinations. Through simultaneous single nucleotide polymorphism (SNP) detection and expression profile determination, more accurate diagnosis for many diseases can be achieved. The assay device can be easily modified to be suitable for detection with general laser-based detection systems such as CD-ROM readers. Information read from the assay device is digitized as software and transmitted to and received by doctors and patients through a computer network or wirelessly, which enables construction of remote diagnosis systems.
Abstract translation: 提供了可应用于定量和定性测定装置的可裂解信号元件，其使用对互补双链或单链核酸特异性响应的可切割技术，以及使用可切割信号元件的核酸杂交测定方法和装置。 使用对互补双链或单链核酸作出反应的可切割技术，可以提高对目标核酸的检测灵敏度，并通过原位测定提高诊断和检测可靠性两倍。 通过同时单核苷酸多态性（SNP）检测和表达谱确定，可以更准确地诊断许多疾病。 测定装置可以容易地被修改为适合于通常的基于激光的检测系统如CD-ROM读取器的检测。 从测定装置读取的信息被数字化为软件，并通过计算机网络或无线传输给医生和患者并由医生和患者接收，这使得能够构建远程诊断系统。
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公开(公告)号：US20100129812A1
公开(公告)日：2010-05-27
申请号：US12585513
申请日：2009-09-16
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
IPC: C12Q1/68
CPC classification number: B82Y30/00 , C12Q1/6823 , G06F19/00 , Y02A90/22 , Y02A90/26 , C12Q2533/101 , C12Q2525/131 , C12Q2521/301 , C12Q2565/625
Abstract: A cleavable signal element applicable to quantitative and qualitative assay devices, using a cleavable technique specifically responsive to a complementary double strand or single strand of nucleic acids, and a nucleic acid hybridization assay method and device using the cleavable signal element are provided. Using the cleavable technique responsive to the complementary double strand or single strand of nucleic acids, detection sensitivity to a target nucleic acid can be increased, and diagnosis and detection reliability can be improved twice through in-situ determinations. Through simultaneous single nucleotide polymorphism (SNP) detection and expression profile determination, more accurate diagnosis for many diseases can be achieved. The assay device can be easily modified to be suitable for detection with general laser-based detection systems such as CD-ROM readers. Information read from the assay device is digitized as software and transmitted to and received by doctors and patients through a computer network or wirelessly, which enables construction of remote diagnosis systems.
Abstract translation: 提供了可应用于定量和定性测定装置的可裂解信号元件，其使用对互补双链或单链核酸特异性响应的可切割技术，以及使用可切割信号元件的核酸杂交测定方法和装置。 使用对互补双链或单链核酸作出反应的可切割技术，可以提高对目标核酸的检测灵敏度，通过原位测定能够提高诊断和检测的可靠性两倍。 通过同时单核苷酸多态性（SNP）检测和表达谱确定，可以更准确地诊断许多疾病。 测定装置可以容易地被修改为适合于通常的基于激光的检测系统如CD-ROM读取器的检测。 从测定装置读取的信息被数字化为软件，并通过计算机网络或无线传输给医生和患者并由医生和患者接收，这使得能够构建远程诊断系统。
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公开(公告)号：US09279818B2
公开(公告)日：2016-03-08
申请号：US11988069
申请日：2006-06-28
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
CPC classification number: G01N35/00069 , G06F19/00 , G06F19/10 , G06F19/702
Abstract: A non-optical bio-disc, a bio-disc device including the non-optical bio-disc and/or optical disc, a bio-driver apparatus in which a controller disc including a controller for the bio-disc is installed, and an assay method using the same, which are suitable for labs-on-a-chips for various diagnostic assays, nucleic acid hybridization assays, and immunoassays, are provided. The bio-driver apparatus is compatible with general optical discs, including audio, CD-ROMs, DVD players, etc. Thus, the bio-driver apparatus and the assay method offer and economical and convenient alternative to existing products. In addition, the bio-driver apparatus can be readily and easily applied in connection with a computer for remote diagnosis via the internet.
Abstract translation: 非光学生物盘，包括非光学生物盘和/或光盘的生物盘装置，其中安装有包括用于生物盘的控制器的控制盘的生物驱动装置，以及 提供了适用于各种诊断测定，核酸杂交测定和免疫测定的芯片实验室的测定方法。 生物驱动装置与普通光盘兼容，包括音频，CD-ROM，DVD播放器等。因此，生物驱动装置和测定方法提供了现有产品的经济和方便的替代方案。 此外，生物驱动装置可以容易地和容易地应用于计算机，以经由因特网进行远程诊断。
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Patent Agency Ranking
公开(公告)号：US08993487B2
公开(公告)日：2015-03-31
申请号：US11919567
申请日：2006-05-02
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
CPC classification number: C12Q1/686 , B01L3/50273 , B01L3/502738 , B01L2200/10 , B01L2200/143 , B01L2300/0806 , B01L2400/0409 , B01L2400/043 , B01L2400/0633 , F16K99/0001
Abstract: A bio-disc device including new valve control means and fluid movement system, a bio-driver apparatus in which a controller disc including a controller for the bio-disc is installed, and an assay method using the same, which are suitable for labs-on-a-chips for various diagnostic assays, nucleic acid hybridization assays, and immunoassays, are provided. The bio-driver apparatus is compatible with general optical discs, including audio CDs, CD-Rs, game CDs, DVDs, etc., and the assay method is compatible with general optical disc drivers, including CD-ROMs, DVD players, etc. Thus, the bio-driver apparatus and the assay method offer and economical and convenient alternative to existing products. In addition, the bio-driver apparatus can be readily and easily applied in connection with a computer for remote diagnosis via the Internet.
Abstract translation: 一种包括新的阀控制装置和流体移动系统的生物盘装置，其中安装有包括用于生物盘的控制器的控制器盘的生物驱动装置，以及使用该控制盘的适用于实验室的测定方法， 提供用于各种诊断测定的芯片，核酸杂交测定和免疫测定。 该生物驱动装置与通用光盘兼容，包括音频CD，CD-R，游戏CD，DVD等，并且该测定方法与通常的光盘驱动器（包括CD-ROM，DVD播放器等）兼容。 因此，生物驱动装置和测定方法为现有产品提供了经济和方便的替代方案。 此外，生物驱动装置可以容易地和容易地应用于计算机，以经由因特网进行远程诊断。
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17.发明授权公开(公告)号：US08969070B2
公开(公告)日：2015-03-03
申请号：US12863684
申请日：2009-01-21
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
CPC classification number: G01N33/5302 , B01L3/502753 , G01N35/00029 , G01N35/00069 , G01N2035/00247 , G01N2035/00495
Abstract: Disclosed herein is a thin-film layered centrifuge device and an analysis method using the same. One example of an embodiment of the present invention is a thin film layered centrifuge device where a device, such as a lab on a chip, a protein chip and a DNA chip, for diagnosing and detecting a small amount of material in a fluid is integrated into a rotatable thin-film layered body, and to an analysis method using the thin-film layered centrifuge device.
Abstract translation: 本发明公开了一种薄膜层状离心机及其分析方法。 本发明的实施例的一个实例是薄膜层状离心机装置，其中用于诊断和检测流体中少量物质的诸如芯片上的实验室，蛋白质芯片和DNA芯片的装置被集成 成为可旋转的薄膜层叠体，以及使用薄膜层状离心机的分析方法。
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公开(公告)号：US08658113B2
公开(公告)日：2014-02-25
申请号：US12743933
申请日：2008-11-11
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
IPC: B01L99/00
CPC classification number: F16K99/0001 , B01L3/502738 , B01L7/00 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2300/1827 , B01L2400/0409 , B01L2400/0677 , B01L2400/0683 , F16K99/0015 , F16K99/0046 , F16K2099/0084 , Y10T137/7737 , Y10T436/2575
Abstract: Provided are a thin film valve device and a thin film valve control apparatus in which a hole or a channel in the body of the thin film valve device is opened and closed using the heat generated from a heat generating apparatus and the centrifugal force. The thin film valve device and the thin film valve control apparatus are applicable to, for example, a diagnostic lab-on-a-chip that can detect a trace amount of a material in a fluid, a rotatable bio-disc in which a bio chip, such as a protein chip and a DNA chip, is integrated, and the like.
Abstract translation: 提供一种薄膜阀装置和薄膜阀控制装置，其中薄膜阀装置的主体中的孔或通道使用从发热装置产生的热量和离心力来打开和关闭。 薄膜阀装置和薄膜阀控制装置可应用于例如可以检测流体中痕量的材料的可诊断实验室，可旋转的生物盘，其中生物 诸如蛋白质芯片和DNA芯片的芯片被集成在一起。
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公开(公告)号：US08480980B2
公开(公告)日：2013-07-09
申请号：US12747117
申请日：2008-12-10
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
IPC: B01L99/00
CPC classification number: G01N35/1097 , B01L3/502715 , B01L3/502738 , B01L2300/0803 , B01L2300/0806 , B01L2300/0867 , B01L2400/0409 , B01L2400/0633 , B01L2400/065 , F16K99/0001 , F16K99/0011 , F16K99/0046 , F16K99/0063 , F16K2099/008 , F16K2099/0084 , G01N2035/00247 , G01N2035/1034 , Y10T436/2575
Abstract: A thin film bio valve device and an apparatus for controlling the thin film bio valve device are effectively applied in a valve structure of a thin film device, such as a lab-on-a-chip, a protein chip, or a DNA chip, for diagnosing and/or detecting a small amount of material in a fluid.
Abstract translation: 薄膜生物阀装置和薄膜生物阀装置的控制装置有效地应用于诸如芯片实验室，蛋白芯片或DNA芯片的薄膜装置的阀结构中， 用于诊断和/或检测流体中的少量物质。
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20.发明授权公开(公告)号：US07635585B2
公开(公告)日：2009-12-22
申请号：US10479004
申请日：2002-05-31
Applicant: Jae Chern Yoo
Inventor： Jae Chern Yoo
CPC classification number: F15C3/06 , B01L3/502738 , B01L2200/10 , B01L2300/0806 , B01L2400/0633 , F16K99/0001 , F16K99/0013 , F16K99/0023 , F16K99/0028 , F16K99/0046 , F16K2099/0078 , G01N35/00069 , G01N2035/00247
Abstract: A micro (thin film type) valve apparatus for controlling fluid flow and its rate using a microbead and a method for controlling the apparatus are provided. The microbead is moved by the magnetic forge generated by upper and lower electromagnets disposed on the top and bottom surface of the body or by the electric field generated by upper and lower electrode plates disposed on the top and bottom surface of the body, thereby interconnecting or blocking flow channels in the body. The micro valve apparatus and the method for controlling the same are suitable for thin film type diagnostic assay devices, such as lab-on-chips, protein chips, or DNA chips, for detecting small quantities of analytes in fluids, and more suitable for interconnecting or blocking channels formed in thin disk type apparatus including general CD-ROMs, DVDs, bioCDs, and bio DVDs.
Abstract translation: 提供了一种用于控制流体流动的微（薄膜型）阀装置及其使用微珠的速率和控制该装置的方法。 微珠通过设置在身体的顶部和底部表面上的上部和下部电磁体产生的磁性锻造或由设置在身体的顶部和底部表面上的上部和下部电极板产生的电场而移动，从而互连或 阻止体内的流动通道。 微阀装置及其控制方法适用于薄膜型诊断测定装置，例如片上实验室，蛋白质芯片或DNA芯片，用于检测流体中的少量分析物，更适合互连 或阻塞通道形成在包括通用CD-ROM，DVD，bioCD和生物DVD的薄盘式设备中。
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