公开(公告)号：US09884888B2

公开(公告)日：2018-02-06

申请号：US15159029

申请日：2016-05-19

Applicant: NANJING TECH UNIVERSITY (CN)

Inventor： Hanjie Ying ,  Chenjie Zhu ,  Qing Li ,  Zhuotao Tan ,  Lingling Pu

IPC: C07H19/207 ,  C12P19/36

CPC classification number: C07H19/207 ,  C12P19/36 ,  Y02P20/584

Abstract: It discloses a chemical regeneration method of oxidized coenzyme NAD(P)+ which is under an oxygen or air atmosphere condition, adding a catalytic amount of bridged flavin, and oxidizing NAD(P)H to obtain NAD(P)+. The catalyst for regeneration of cofactor is cheap and easily available small organic molecule having no noble metal; this regeneration system can regenerate NADH and NADPH; this regeneration system has a wide pH range and temperature range, being applicable to various oxidation reactions catalyzed by nicotinamide-dependent oxidoreductase.