Process to produce polyolefin ionomers and ionomers produced thereby

    公开(公告)号:US10167360B2

    公开(公告)日:2019-01-01

    申请号:US15111178

    申请日:2014-12-15

    Abstract: A process to produce an ionomer comprising reacting alkyl-cis-cyclooctene and cis-cyclooctene in a mole ratio from 1:0 to 0:1, in the presence of a difunctional chain transfer agent under ring opening metathesis polymerization conditions to form an unsaturated polyolefin reactive telechelic pre-polymer; hydrogenating the unsaturated polyolefin reactive telechelic pre-polymer to produce a hydrogenated polyolefin reactive telechelic pre-polymer; reacting the hydrogenated polyolefin reactive telechelic pre-polymer with at least one compound according to the formula aMx+b(R)y, wherein M is a metal, x is a charge of M, R is an alkyl, aryl, oxide, or fatty acid, y is a charge of R, a and b are integers of at least 1, and ax+by=0, to form an ionomer is provided. Further provided are ionomers produced thereby.

    CELLULOSE ETHERS ESTERIFIED WITH DICARBOXYLIC ACID
    19.
    发明申请
    CELLULOSE ETHERS ESTERIFIED WITH DICARBOXYLIC ACID 有权
    用二羧酸测定的纤维素

    公开(公告)号:US20160289344A1

    公开(公告)日:2016-10-06

    申请号:US14777838

    申请日:2014-05-07

    CPC classification number: C08B13/00 A61K9/146 A61K31/095 A61K31/4166 A61K47/38

    Abstract: Esterified cellulose ethers comprising groups of formula —C(O)—CHR′—CHR″—COOA, wherein, R′ and R″ are hydrogen or (—S)m (—R1)n-R2, wherein R1 is a hydrocarbon group having 1 to 4 carbon atoms, R2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR′—CHR″ one of R′ and R″ is hydrogen and the other one is (—S)m (—R1)n-R′, are useful as excipients for maintaining the concentration of poorly water-soluble drugs in aqueous liquids at supersaturation levels.

    Abstract translation: 包含式-C(O)-CHR'-CHR“-COOA基团的酯化纤维素醚,其中R'和R”是氢或(-S)m(-R1)n -R2,其中R1是烃基 具有1至4个碳原子,R 2是任选取代的5或6元环基,m和n各自独立地是0或1,A是氢或阳离子,条件是在CHR'-CHR “R”和R“之一是氢,另一个是(-S)m(-R1)nR',可用作在过饱和水平下维持水溶液中难溶于水的药物浓度的赋形剂。

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