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公开(公告)号:US20180108275A1
公开(公告)日:2018-04-19
申请号:US15707914
申请日:2017-09-18
Applicant: Sanmina Corporation
Inventor: Robert Newberry , Matthew Rodencal , Nate Roth
CPC classification number: G09B23/303 , A61B5/02 , A61B5/145 , A61B5/1495 , A61B2560/0223 , F03B13/14 , Y02E10/38
Abstract: A blood flow simulator generates a compression and expansion in a test fluid that emulates the pressure waveform created by a heartbeat in blood flow. The blood flow simulator stores a plurality of pressure waveform files that include actual data recorded from a heartbeat, arterial pressure waveform, or venous pressure waveform. One or more of the pressure waveform files may be selected and the pressure waveform file is used by the blood flow simulator 100 to generate a pressure waveform in pressurized fluid. The pressurized fluid flows through a test site, such as a surrogate body part or an optical window or other component with material having similar properties to human tissue. Various target substances may also be added to the fluid in known concentrations for testing and configuration of medical devices at the test site.
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公开(公告)号:US09636457B2
公开(公告)日:2017-05-02
申请号:US15276760
申请日:2016-09-26
Applicant: Sanmina Corporation
Inventor: Robert Steven Newberry , Matthew Rodencal
CPC classification number: A61M5/1723 , A61M5/14248 , A61M5/145 , A61M5/3298 , A61M2205/3306 , A61M2205/3584 , A61M2205/502 , A61M2205/52 , A61M2205/8206 , A61M2205/8268 , A61M2230/06 , A61M2230/20 , A61M2230/30 , A61M2230/42 , A61M2230/50 , A61M2230/63
Abstract: An integrated drug delivery and biosensor (IDDB) system is implemented on a patch or arm band. The drug delivery system includes needles adapted to pierce the skin and direct injection of a predetermined dosage of medication through the needles into the epidermis of the skin of a patient. The integrated biosensor monitors absorption of the medication into the epidermis of the skin of the patient and may also monitor concentration of the medication or other relevant substances in arterial blood flow of the patient. The integrated biosensor may also monitor a patient's vitals in response to the medication. The integrated biosensor may then alter dosage or frequency of administration of dosages or even halt a dosage of medication in response to the patient's vitals or absorption of the medication.
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公开(公告)号:US20210186435A1
公开(公告)日:2021-06-24
申请号:US17192743
申请日:2021-03-04
Applicant: SANMINA CORPORATION
Inventor: Robert Steven Newberry , Matthew Rodencal
Abstract: A photoplethysmography (PPG) circuit obtains PPG signals at a plurality of wavelengths of light reflected from tissue of a user. A processing device generates parameters using the PPG signals to screen the user for an infection, such as sepsis, influenza and/or COVID-19. The processing device may also determine a severity level of the infection and a confidence level in the determination. The parameters may include a measurement of nitric oxide (NO) level, respiration rate, heart rate and/or oxygen saturation.
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公开(公告)号:US10973470B2
公开(公告)日:2021-04-13
申请号:US16848646
申请日:2020-04-14
Applicant: Sanmina Corporation
Inventor: Robert Steven Newberry , Matthew Rodencal
Abstract: A photoplethysmography (PPG) circuit obtains PPG signals at a plurality of wavelengths of light reflected from tissue of a user. A processing device generates parameters using the PPG signals to screen the user for an infection, such as sepsis, influenza and/or COVID-19. The processing device may also determine a severity level of the infection and a confidence level in the determination. The parameters may include a measurement of nitric oxide (NO) level, respiration rate, heart rate and/or oxygen saturation.
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公开(公告)号:US10952682B2
公开(公告)日:2021-03-23
申请号:US16779453
申请日:2020-01-31
Applicant: Sanmina Corporation
Inventor: Robert Steven Newberry , Matthew Rodencal
Abstract: A photoplethysmography (PPG) circuit obtains PPG signals at a plurality of wavelengths of light reflected from tissue of a user. A processing device generates parameters using the PPG signals to determine a glucose level in blood flow of the user. The parameters include one or more ratio values obtained using the plurality of PPG signals; a phase delay between the plurality of PPG signals; a correlation of phase shape between the plurality of PPG signals or a periodicity of one or more of the plurality of PPG signals.
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公开(公告)号:US20200237317A1
公开(公告)日:2020-07-30
申请号:US16779453
申请日:2020-01-31
Applicant: Sanmina Corporation
Inventor: Robert Steven Newberry , Matthew Rodencal
Abstract: A photoplethysmography (PPG) circuit obtains PPG signals at a plurality of wavelengths of light reflected from tissue of a user. A processing device generates parameters using the PPG signals to determine a glucose level in blood flow of the user. The parameters include one or more ratio values obtained using the plurality of PPG signals; a phase delay between the plurality of PPG signals; a correlation of phase shape between the plurality of PPG signals or a periodicity of one or more of the plurality of PPG signals.
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公开(公告)号:US20190076601A1
公开(公告)日:2019-03-14
申请号:US16183354
申请日:2018-11-07
Applicant: Sanmina Corporation
Inventor: Robert Steven Newberry , Matthew Rodencal
CPC classification number: A61M5/1723 , A61M5/14248 , A61M5/145 , A61M5/3298 , A61M2205/3306 , A61M2205/3584 , A61M2205/502 , A61M2205/52 , A61M2205/8206 , A61M2205/8268 , A61M2230/06 , A61M2230/20 , A61M2230/30 , A61M2230/42 , A61M2230/50 , A61M2230/63
Abstract: A biosensor is implemented in an earpiece and includes an activity monitoring circuit that detects an activity level of a user and an optical circuit that detects a plurality of spectral responses at a plurality of wavelengths from light reflected from skin of the user. The biosensor determines a heart rate and an oxygen saturation level using the plurality of spectral responses and determines whether the heart rate or the oxygen saturation level reaches a predetermined threshold for the activity level of the user. The biosensor generates an alert and transmits the alert wirelessly to a remote device.
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公开(公告)号:US20170274146A1
公开(公告)日:2017-09-28
申请号:US15485816
申请日:2017-04-12
Applicant: Sanmina Corporation
Inventor: Robert Steven Newberry , Matthew Rodencal
CPC classification number: A61M5/1723 , A61M5/14248 , A61M5/145 , A61M5/3298 , A61M2205/3306 , A61M2205/3584 , A61M2205/502 , A61M2205/52 , A61M2205/8206 , A61M2205/8268 , A61M2230/06 , A61M2230/20 , A61M2230/30 , A61M2230/42 , A61M2230/50 , A61M2230/63
Abstract: A biosensor detects a medication applied to an upper epidermal layer of skin of a user. The biosensor obtains at periodic intervals a concentration level of the medication in the upper epidermal layer of skin and surrounding tissue of the user. The biosensor may also detect the concentration level of the medication in an arterial blood flow of the patient or obtain a concentration level of a substance in the arterial blood flow, wherein the concentration level of the substance correlates to a first concentration level of the medication. The biosensor may determine an absorption rate of the medication in the upper epidermal layer of skin and surrounding tissue and in an arterial blood flow of the patient from the detected concentration levels of the medication obtained at the periodic intervals.
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