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公开(公告)号：US08790339B2
公开(公告)日：2014-07-29
申请号：US13443503
申请日：2012-04-10
Applicant: Stuart D Edwards , David S Utley , Ronald G Lax
Inventor： Stuart D Edwards , David S Utley , Ronald G Lax
IPC: A61B18/14
CPC classification number: A61B5/04884 , A61B18/1477 , A61B18/1485 , A61B90/39 , A61B2018/00553 , A61B2018/00738 , A61B2018/046 , A61B2090/3925 , A61B2560/0242
Abstract: An apparatus to treat a sphincter has a support member. A sphincter electropotential mapping device includes a mapping electrode. The sphincter electropotential mapping device is coupled to the support member and configured to detect aberrant myoelectric activity of the sphincter.
Abstract translation: 治疗括约肌的装置具有支撑构件。 括约肌电位映射装置包括映射电极。 括约肌电位映射设备耦合到支撑构件并且被配置为检测括约肌的异常肌电活动。
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12.发明授权Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors 有权通过检测和消融胃食管神经和受体来治疗胃反流的方法公开(公告)号：US07585296B2
公开(公告)日：2009-09-08
申请号：US11230801
申请日：2005-09-20
Applicant: Stuart D Edwards , John Gaiser , David S Utley
Inventor： Stuart D Edwards , John Gaiser , David S Utley
IPC: A61B18/18
CPC classification number: A61B18/1233 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B2017/00039 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00142 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00553 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00738 , A61B2018/00791 , A61B2018/00821 , A61B2018/00839 , A61B2018/00875 , A61B2018/00898 , A61B2018/0091 , A61B2018/00982 , A61B2018/0237 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2090/064 , A61B2090/3782 , A61B2218/002 , A61N1/06
Abstract: A method detects at a tissue site an electrical activity causing a transient relaxation of at least a portion of one of a sphincter, a lower esophageal sphincter, a stomach, a cardia or a fundus. The method treats the electrical activity at the tissue site by delivering electromagnetic energy to ablate at least a portion of one of the nerve, the gastric nerve, a nerve plexus, a myenteric nerve plexus, a ganglia, a nerve pathway or an electrically conductive pathway. The method conducts a cooling solution to the tissue site at a flow rate and adjusts the flow rate in response to sensed temperature conditions.
Abstract translation: 一种方法在组织位置处检测导致括约肌，下食道括约肌，胃，贲门或眼底之一的至少一部分的暂时松弛的电活动。 该方法通过传递电磁能来消除组织部位的电活动，以消融神经，胃神经，神经丛，肌间神经丛，神经节，神经通路或导电通路中的至少一部分 。 该方法以流量对组织部位进行冷却溶液，并根据感测的温度条件调节流速。
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公开(公告)号：US06846312B2
公开(公告)日：2005-01-25
申请号：US10230655
申请日：2002-08-29
Applicant: Stuart D Edwards , David S Utley
Inventor： Stuart D Edwards , David S Utley
CPC classification number: A61B18/1492 , A61B18/1206 , A61B18/1477 , A61B2017/003 , A61B2017/22061 , A61B2018/00011 , A61B2018/00077 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00553 , A61B2018/00654 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00797 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2018/1472 , A61B2090/3782
Abstract: An apparatus to treat a sphincter includes an energy delivery device support member. An energy delivery device is coupled to the energy delivery support member. The energy delivery device has a configuration that controllably produces lesions of a sufficient size and number in the sphincter to create a selectable tightening of the sphincter.
Abstract translation: 治疗括约肌的装置包括能量输送装置支撑构件。 能量输送装置联接到能量输送支撑构件。 能量输送装置具有可控制地产生足够尺寸和数量的括约肌中的损伤以构成括约肌的可选择紧固的构造。
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14.发明授权Systems and methods for forming composite lesions to treat dysfunction in sphincters and adjoining tissue regions 有权用于形成复合损伤以治疗括约肌和邻近组织区域的功能障碍的系统和方法公开(公告)号：US06712074B2
公开(公告)日：2004-03-30
申请号：US10155294
申请日：2002-05-24
Applicant: Stuart D Edwards , John Gaiser , David S Utley , Scott H West , Jay Qin
Inventor： Stuart D Edwards , John Gaiser , David S Utley , Scott H West , Jay Qin
IPC: A61B1900
CPC classification number: A61B18/1206 , A61B18/12 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
Abstract: Systems and methods manipulate a support structure to form a composite lesion in a tissue region at or near a sphincter. The support structure carries an array of electrodes attachable to a source of energy capable of heating tissue when transmitted by the electrodes. The systems and methods advance the electrodes to penetrate the tissue region and form, when the energy is transmitted, a first pattern of lesions. The systems and methods retract the electrodes, and shift the position of the electrodes, either rotationally, or axially, or both rotationally and axially. The systems and methods advance the electrodes a second time to form, when the energy is transmitted, a second pattern of lesions either rotationally or axially or both rotationally and axially shifted from the first pattern of lesions. The first and second patterns of lesion together comprise the composite lesion.
Abstract translation: 系统和方法操纵支撑结构以在括约肌处或附近的组织区域中形成复合损伤。 支撑结构带有可连接到能够通过电极传输的能够加热组织的能量源的电极阵列。 系统和方法使电极穿过组织区域并在能量传输时形成第一种损伤模式。 系统和方法缩回电极，并且可旋转地或轴向地或者旋转地和轴向地移动电极的位置。 系统和方法第二次推进电极，当能量传递时，可以旋转地或轴向地或者从第一病变图案旋转地和轴向移动的第二病变图案。 病灶的第一和第二模式一起构成复合损伤。
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公开(公告)号：US08518032B2
公开(公告)日：2013-08-27
申请号：US12291626
申请日：2008-11-12
Applicant: Stuart D Edwards , David S Utley , Ronald G Lax , John Gaiser
Inventor： Stuart D Edwards , David S Utley , Ronald G Lax , John Gaiser
IPC: A61B18/14
CPC classification number: A61B18/1492 , A61B18/1206 , A61B18/1477 , A61B18/18 , A61B2018/00011 , A61B2018/00029 , A61B2018/00047 , A61B2018/00214 , A61B2018/0022 , A61B2018/00494 , A61B2018/00553 , A61B2018/00666 , A61B2018/00678 , A61B2018/00684 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2218/002
Abstract: A method for treating a sphincter provides a polymer material having a liquid state. The method also provides a catheter having a distal end, a tissue piercing device carried by the distal end, and an energy delivery device coupled to the tissue piercing device. The tissue piercing device has a lumen. The method introduces the catheter into an esophagus and pierces an exterior sphincter tissue surface within with the tissue piercing device. The method advances the tissue piercing device into an interior sphincter tissue site and conveys the polymer material while in a liquid state through the lumen into the interior sphincter tissue site. The method delivers energy to the tissue piercing device to transform the polymer material into a less liquid state within the interior sphincter tissue site, to thereby remodel the sphincter.
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Patent Agency Ranking
公开(公告)号：US07556628B2
公开(公告)日：2009-07-07
申请号：US11420722
申请日：2006-05-26
Applicant: David S Utley , John Gaiser , Stuart D Edwards , Scott H West , Jay Qin
Inventor： David S Utley , John Gaiser , Stuart D Edwards , Scott H West , Jay Qin
IPC: A61B18/18
CPC classification number: A61B18/1492 , A61B18/12 , A61B18/1206 , A61B18/1477 , A61B18/1485 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
Abstract: Methods of ablating mucosal tissue in an alimentary canal are provided. The methods can include the steps of (i) providing an ablation device comprising a tissue ablation source; (ii) positioning at least a portion of the ablation device at a mucosal tissue surface of the alimentary canal; (iii) delivering a sufficient amount of the source for tissue ablation to the mucosal tissue surface to create a lesion in the mucosal tissue. In one implementation the methods include a step of providing a radiofrequency (RF) energy delivery device.
Abstract translation: 提供消化道中消融粘膜组织的方法。 所述方法可以包括以下步骤：（i）提供包括组织消融源的消融装置; （ii）将消融装置的至少一部分定位在消化道的粘膜组织表面; （iii）将足够量的用于组织消融的来源输送到粘膜组织表面以在粘膜组织中产生损伤。 在一个实现中，所述方法包括提供射频（RF）能量传递装置的步骤。
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公开(公告)号：US07507238B2
公开(公告)日：2009-03-24
申请号：US11420719
申请日：2006-05-26
Applicant: Stuart D Edwards , John Gaiser , David S Utley , Scott West , Jay Qin
Inventor： Stuart D Edwards , John Gaiser , David S Utley , Scott West , Jay Qin
CPC classification number: A61B18/1492 , A61B18/12 , A61B18/1206 , A61B18/1477 , A61B18/1485 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
Abstract: Methods of accessing and ablating abnormal epithelium tissue in an alimentary canal are provided. The methods can include steps of (i) inserting a vacuum source comprising one or more suction ports into an alimentary canal; (ii) inserting an operative element comprising a conduit for a tissue ablation source into the alimentary canal; (iii) positioning the vacuum source and the operative element proximate a portion of the alimentary canal having a site of abnormal tissue to be ablated; (iv) applying a vacuum to at least one of each suction port to draw the tissue against the operative element; and (v) applying the tissue ablation source to the tissue through the conduit to effect tissue ablation.
Abstract translation: 提供了在消化道中获取和消融异常上皮组织的方法。 所述方法可以包括以下步骤：（i）将包括一个或多个吸入口的真空源插入消化道; （ii）将包括用于组织消融源的导管的操作元件插入消化道中; （iii）将真空源和操作元件定位在具有要消融的异常组织部位的消化道的一部分附近; （iv）向每个抽吸口中的至少一个施加真空以将组织拉向操作元件; 和（v）通过导管将组织消融源施加到组织以实现组织消融。
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公开(公告)号：US07165551B2
公开(公告)日：2007-01-23
申请号：US09924935
申请日：2001-08-08
Applicant: Stuart D Edwards , David S Utley , Ronald G Lax
Inventor： Stuart D Edwards , David S Utley , Ronald G Lax
CPC classification number: A61B5/04884 , A61B18/1477 , A61B18/1485 , A61B90/39 , A61B2018/00553 , A61B2018/00738 , A61B2018/046 , A61B2090/3925 , A61B2560/0242
Abstract: An apparatus to treat a sphincter has a support member. A sphincter electropotential mapping device includes a mapping electrode. The sphincter electropotential mapping device is coupled to the support member and configured to detect aberrant myoelectric activity of the sphincter.
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公开(公告)号：US06402744B2
公开(公告)日：2002-06-11
申请号：US09304750
申请日：1999-05-04
Applicant: Stuart D Edwards , John Gaiser , David S Utley , Scott West , Jay Qin
Inventor： Stuart D Edwards , John Gaiser , David S Utley , Scott West , Jay Qin
IPC: A61B1818
CPC classification number: A61B18/1206 , A61B18/12 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
Abstract: Systems and methods manipulate a support structure to form a composite lesion in a tissue region at or near a sphincter. The support structure carries an array of electrodes attachable to a source of energy capable of heating tissue when transmitted by the electrodes. The systems and methods advance the electrodes to penetrate the tissue region and form, when the energy is transmitted, a first pattern of lesions. The systems and methods retract the electrodes, and shift the position of the electrodes, either rotationally, or axially, or both rotationally and axially. The systems and methods advance the electrodes a second time to form, when the energy is transmitted, a second pattern of lesions either rotationally or axially or both rotationally and axially shifted from the first pattern of lesions. The first and second patterns of lesion together comprise the composite lesion.
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公开(公告)号：US08454595B2
公开(公告)日：2013-06-04
申请号：US12653018
申请日：2009-12-07
Applicant: Stuart D Edwards , David S. Utley , Ronald G Lax , Theodore R Kucklick , Peter H Muller
Inventor： Stuart D Edwards , David S. Utley , Ronald G Lax , Theodore R Kucklick , Peter H Muller
IPC: A61B18/14
CPC classification number: A61B18/14 , A61B17/32 , A61B18/1477 , A61B18/1492 , A61B18/1815 , A61B2018/00011 , A61B2018/00029 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00577 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00875 , A61B2018/00916 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1472 , A61B2018/183 , A61B2090/3614 , A61B2090/3782
Abstract: A sphincter treatment apparatus includes an energy delivery device introduction member including a proximal end with a first radius of curvature and a distal end with a second radius of curvature. The introduction member is configured to be introduced into the sphincter in a non-deployed state and to be expanded to a deployed state to at least partially expand the sphincter or an adjoining structure. An energy delivery device is coupled to the introduction member. A retainer member is coupled to the energy delivery device introduction member and configured to controllably position the introduction member in an orifice of the sphincter.
Abstract translation: 括约肌治疗装置包括能量输送装置导入构件，其包括具有第一曲率半径的近端和具有第二曲率半径的远端。 引入构件被配置为以非展开状态引入括约肌并且被扩展到展开状态以至少部分地扩展括约肌或相邻结构。 能量输送装置联接到引入构件。 保持器构件联接到能量输送装置引入构件并构造成将引导构件可控地定位在括约肌的孔中。
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