公开(公告)号：US20220370086A1

公开(公告)日：2022-11-24

申请号：US17881684

申请日：2022-08-05

Applicant: Lawrence Livermore National Security, LLC ,  The Texas A&M University System

Inventor： Jason Szafron ,  Duncan Maitland ,  Ward Small, IV ,  Patrick R. Buckley ,  Andrea D. Muschenborn

IPC: A61B17/22

Abstract: An embolectomy device comprised of an expansion unit and a support unit is disclosed. The expansion unit can be actuated in response to one or more external stimuli, and the support unit, located proximately to the expansion unit, provides a force to hold the expansion unit in place and to further induce the expansion unit's radial expansion. The radial expansion of the expansion unit causes the expansion unit to physically contact a blood clot, enabling the blood clot to be removed. In some embodiments, the expansion unit can be fabricated from a shape memory polymer foam. In some embodiments the support unit can be fabricated from any elastic material including, without limitation, shape memory alloys.

公开(公告)号：US20220304667A1

公开(公告)日：2022-09-29

申请号：US17837111

申请日：2022-06-10

Applicant: THE TEXAS A&M UNIVERSITY SYSTEM

Inventor： Mark A. Wierzbicki ,  Duncan Maitland ,  Matthew W. Miller ,  Andrea D. Muschenborn ,  Landon Nash ,  Jason M. Szafron ,  Todd Landsman

IPC: A61B17/00

Abstract: A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.

公开(公告)号：US20220105249A1

公开(公告)日：2022-04-07

申请号：US17495009

申请日：2021-10-06

Applicant: The Texas A&M University System ,  Shape Memory Medical, Inc.

Inventor： Grace Fletcher ,  Duncan Maitland ,  Landon Nash ,  Todd Landsman ,  Chung Yeh ,  Edward Ruppel ,  Meghan Reu

IPC: A61L31/14 ,  A61L31/18 ,  A61L31/06 ,  A61K49/04 ,  A61K49/18

Abstract: An embodiment includes a shape memory polymer (SMP) foam with visibility under both X-ray and magnetic resonance imaging (MRI) modalities. Dual modality visibility is achieved by chemically incorporating monomers with X-ray visible iodine-motifs and MRI visible monomers with gadolinium content. This material platform has the potential to be used in a variety of medical devices.

公开(公告)号：US10555737B2

公开(公告)日：2020-02-11

申请号：US15567682

申请日：2016-04-22

Applicant: The Texas A&M University System

Inventor： Mark A. Wierzbicki ,  Duncan Maitland ,  Matthew W. Miller ,  Andrea D. Muschenborn ,  Landon Nash ,  Jason M. Szafron ,  Todd Landsman

IPC: A61B17/12 ,  A61L31/14 ,  A61L31/02 ,  A61L31/04 ,  A61B17/00

Abstract: A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.