公开(公告)号：US08777413B2

公开(公告)日：2014-07-15

申请号：US13459914

申请日：2012-04-30

Applicant: Yan Zhou ,  William Shea ,  Phil Baker

Inventor： Yan Zhou ,  William Shea ,  Phil Baker

IPC: A61B3/14 ,  A61B3/10 ,  A61B3/103 ,  A61B3/12

CPC classification number: A61B3/1015 ,  A61B3/103 ,  A61B3/12 ,  G01J1/0414 ,  G01J1/0437 ,  G01J9/00

Abstract: One embodiment of the present invention is an ophthalmic wavefront sensor for use with an ophthalmic microscope to provide continuous measurements of the refractive state of an eye. The wavefront sensor operates in both parallel sampling and lock-in detection mode by synchronizing the pulsing of the light source with a multiple number of position sensing devices/detectors used for detecting the centroid position of the sampled sub-wavefronts. Other embodiments include a beam scanner to sample selected portions of the wavefront and a live image sensor and a tracking deflector.

Abstract translation: 本发明的一个实施例是眼用波前传感器，用于与眼科显微镜一起提供眼睛的屈光状态的连续测量。 通过使光源的脉冲与用于检测采样子波前的质心位置的多个位置感测装置/检测器同步，波前传感器以并行采样和锁定检测模式工作。 其他实施例包括用于对波前的选定部分进行采样的光束扫描器以及实时图像传感器和跟踪偏转器。

公开(公告)号：US08518109B2

公开(公告)日：2013-08-27

申请号：US12606017

申请日：2009-10-26

Applicant: William Shea ,  Barry Linder ,  Phillip Baker ,  Yan Zhou

Inventor： William Shea ,  Barry Linder ,  Phillip Baker ,  Yan Zhou

IPC: A61F2/16 ,  A61F2/14

CPC classification number: A61K9/0048 ,  A61B3/00 ,  A61B3/125 ,  A61K49/00

Abstract: The invention discloses an optical coupling gel that has a set of desired features for application in eye imaging, including being approved for eye contact, optically transparent, able to maintain normal hydration of the ocular surface, flexible and capable of maintaining a distinct shape, minimal in breakdown/change during use, and easily dispensable/applicable. In one embodiment, the gel is made of Sodium Carboxy Methylcellulose (SCMC), where the amount of the cellulose determines the viscosity of the gel for its particular application. The right amount of gel is contained in an applicator for application to one or two eyes.

Abstract translation: 本发明公开了一种光学耦合凝胶，其具有用于眼睛成像中的一组所需特征，包括被认可用于眼睛接触，光学透明的，能够保持眼表面的正常水合，柔性并能够保持不同形状，最小化 在使用过程中发生故障/更换，并且易于安装/适用。 在一个实施方案中，凝胶由羧甲基纤维素钠（SCMC）制成，其中纤维素的量决定了其特定用途的凝胶的粘度。 适量的凝胶包含在施用于一只或两只眼睛的施用器中。

公开(公告)号：US08356900B2

公开(公告)日：2013-01-22

申请号：US13198442

申请日：2011-08-04

Applicant: Yan Zhou ,  William Shea

Inventor： Yan Zhou ,  William Shea

IPC: A61B3/10

CPC classification number: A61B3/1015 ,  A61B3/1005 ,  A61B3/102 ,  A61B3/103 ,  A61B3/107 ,  A61B3/117 ,  G01J9/00 ,  G01J2003/064 ,  G02B13/0095 ,  G02B17/0896

Abstract: Example embodiments of a large dynamic range sequential wavefront sensor for vision correction or assessment procedures are disclosed. An example embodiment optically relays a wavefront from an eye pupil or corneal plane to a wavefront sampling plane in such a manner that somewhere in the relaying process, the wavefront beam from the eye within a large eye diopter range is made to reside within a desired physical dimension over a certain axial distance range in a wavefront image space and/or a Fourier transform space. As a result, a wavefront beam shifting device can be disposed there to fully intercept and hence shift the whole beam to transversely shift the relayed wavefront.

Abstract translation: 公开了用于视力矫正或评估过程的大动态范围连续波前传感器的示例实施例。 一个示例性实施例将波前从眼睛瞳孔或角膜平面中继到波前采样平面，使得在中继过程中的某个地方，来自大眼睛屈光度范围内的眼睛的波前光束被放置在期望的物理 在波前图像空间和/或傅里叶变换空间中的某个轴向距离范围内的尺寸。 结果，波前波束移动装置可以放置在那里以完全拦截并因此移动整个波束以横向移动中继的波前。

公开(公告)号：US08002410B2

公开(公告)日：2011-08-23

申请号：US12643945

申请日：2009-12-21

Applicant: William Shea

Inventor： William Shea

IPC: A61B3/10

CPC classification number: A61B3/1015 ,  A61B3/0025 ,  A61B3/0041 ,  A61B3/0091 ,  A61B3/036 ,  A61B3/10 ,  A61B3/103 ,  A61B3/1035 ,  A61B3/13 ,  A61B3/14 ,  A61B5/7415 ,  A61B90/20 ,  G01J9/00 ,  G01J2003/064

Abstract: One embodiment of the present invention is a method to not limit the device's manipulation of the data to that of the manufacturer, but to allow greater freedom for customization by the individual user for their preference.

Abstract translation: 本发明的一个实施例是一种不限制设备对制造商的数据操纵的方法，而是允许个人用户为自己的偏好而更大的自定义度。

公开(公告)号：US20100118269A1

公开(公告)日：2010-05-13

申请号：US12606982

申请日：2009-10-27

Applicant: William Shea ,  Phillip Baker ,  Barry Linder

Inventor： William Shea ,  Phillip Baker ,  Barry Linder

IPC: A61B3/117 ,  G02B21/18 ,  A61B3/13

CPC classification number: G02B21/18 ,  A61B3/13 ,  G02B21/0012

Abstract: This invention discloses an apparatus that is attached to the objective lens of a microscope to split its field of view into at least two. In one embodiment, a mirrored gonio lens is snapped to the objective of an ophthalmic surgical microscope to provide a view of the eye's anterior surface and a view of the eye's anterior chamber.

Abstract translation: 本发明公开了一种附着在显微镜的物镜上以将其视场分成至少两个的装置。 在一个实施例中，镜像的镜角镜被咬合到眼科手术显微镜的目的，以提供眼睛前表面的视图和眼睛前房的视图。

公开(公告)号：US20060264721A1

公开(公告)日：2006-11-23

申请号：US11495415

申请日：2006-07-28

Applicant: Ethan Petersen ,  William Shea ,  Bradford Chew

Inventor： Ethan Petersen ,  William Shea ,  Bradford Chew

IPC: A61B5/00

CPC classification number: A61B5/14552 ,  A61B5/0205 ,  A61B5/02416 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7225 ,  A61B5/7228 ,  A61B5/725 ,  A61B5/7278

Abstract: A pulse oximeter method and apparatus which provides (1) a notch filter at a distance between a modulation frequency and a common multiple of commonly used power line frequencies (50, 60, 100 and 120) and also (2) a demodulation frequency greater than a highest pulse rate of a person and lower than any harmonic of 50, 60, 100 or 120 Hz, to filter ambient light interference, while choosing an optimum demodulation frequency that avoids interference from the notch filter or from harmonics of the line interference. Also, ambient light for any low frequency interference, such as power line interference, is measured both before and after each of the light emitter wavelengths and the average of the ambient light is then subtracted from the detected signal.

Abstract translation: 一种脉冲血氧计方法和装置，其提供（1）陷波滤波器，其在调制频率和共同使用的电力线频率（50,60,100和120）的公倍数之间的距离处，以及（2）大于 一个人的最高脉冲频率，低于50,60,100或120Hz的任何谐波，以过滤环境光干扰，同时选择避免陷波滤波器干扰或线干扰谐波的最佳解调频率。 此外，在每个发光体波长之前和之后都测量任何低频干扰（例如电力线干扰）的环境光，然后从检测到的信号中减去环境光的平均值。

公开(公告)号：US20060264720A1

公开(公告)日：2006-11-23

申请号：US11494394

申请日：2006-07-26

Applicant: Bradford Chew ,  Ethan Petersen ,  William Shea

Inventor： Bradford Chew ,  Ethan Petersen ,  William Shea

IPC: A61B5/00 ,  H05B37/00

CPC classification number: A61B5/14551

Abstract: A light emitter drive circuit for an oximeter which utilizes a single inductor for driving multiple light emitters. The inductor is connected to a switching circuit to multiple energy storage circuits, such as capacitors. These are alternately charged up, using the same inductor. Subsequently, the capacitors are alternatively discharged for their corresponding light emitters through he same inductor. Also, the magnetic susceptibility of the LED drive circuit is reduced by using magnetic flux canceling in the inductor. In one embodiment, a toroidal inductor is used with geometric symmetry and its magnetic flux. In other embodiment, a dual core closed bobbin shielded inductor is used.

Abstract translation: 一种用于血氧计的光发射器驱动电路，其利用单个电感器来驱动多个发光体。 电感器连接到开关电路到多个储能电路，如电容器。 这些交替电荷使用相同的电感。 随后，电容器通过相同的电感器交替地放电用于它们对应的发光体。 此外，通过在电感器中使用磁通量消除来减少LED驱动电路的磁化率。 在一个实施例中，使用具有几何对称性及其磁通量的环形电感器。 在另一个实施例中，使用双核闭合筒管屏蔽电感器。

公开(公告)号：US07120479B2

公开(公告)日：2006-10-10

申请号：US10787852

申请日：2004-02-25

Applicant: Bradford B Chew ,  Ethan Petersen ,  William Shea

Inventor： Bradford B Chew ,  Ethan Petersen ,  William Shea

IPC: A61B5/00 ,  H05B37/00

CPC classification number: A61B5/14551

Abstract: A light emitter drive circuit for an oximeter which utilizes a single inductor for driving multiple light emitters. The inductor is connected to a switching circuit to multiple energy storage circuits, such as capacitors. These are alternately charged up, using the same inductor. Subsequently, the capacitors are alternately discharged for their corresponding light emitters through the same inductor. Also, the magnetic susceptibility of the LED drive circuit is reduced by using magnetic flux canceling in the inductor. In one embodiment, a toroidal inductor is used with geometric symmetry and its magnetic flux. In another embodiment, a dual core closed bobbin shielded inductor is used.

Abstract translation: 一种用于血氧计的光发射器驱动电路，其利用单个电感器来驱动多个发光体。 电感器连接到开关电路到多个储能电路，如电容器。 这些交替电荷使用相同的电感。 随后，电容器通过相同的电感器交替地对其相应的发光体放电。 此外，通过在电感器中使用磁通量消除来减少LED驱动电路的磁化率。 在一个实施例中，使用具有几何对称性及其磁通量的环形电感器。 在另一个实施例中，使用双核闭合筒管屏蔽电感器。

公开(公告)号：US20050187453A1

公开(公告)日：2005-08-25

申请号：US10787853

申请日：2004-02-25

Applicant: Ethan Petersen ,  William Shea ,  Bradford Chew

Inventor： Ethan Petersen ,  William Shea ,  Bradford Chew

IPC: A61B5/00 ,  H03M7/32

CPC classification number: A61B5/14551 ,  H03M7/3028 ,  H03M7/3042

Abstract: A method and apparatus for providing a substantially real-time representation of an analog representation of a physiological signal. The waveform signal from the sensor is converted into digital form. A delta-sigma modulator is used as a simple Digital-to-analog Converter (ADC). The output can then be provided through a simple hardware filter to give an analog output signal in nearly real-time, which can be used for other instruments, synchronization, display, etc.

Abstract translation: 一种用于提供生理信号的模拟表示的基本上实时表示的方法和装置。 传感器的波形信号转换为数字形式。 Δ-Σ调制器用作简单的数模转换器（ADC）。 然后可以通过简单的硬件滤波器提供输出，几乎实时提供模拟输出信号，可用于其他仪器，同步，显示等。

公开(公告)号：US08315684B2

公开(公告)日：2012-11-20

申请号：US12172981

申请日：2008-07-14

Applicant: Ethan Petersen ,  William Shea ,  Bradford B. Chew

Inventor： Ethan Petersen ,  William Shea ,  Bradford B. Chew

IPC: A61B5/1455

CPC classification number: A61B5/14552 ,  A61B5/0205 ,  A61B5/02416 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7225 ,  A61B5/7228 ,  A61B5/725 ,  A61B5/7278

Abstract: A pulse oximeter method and apparatus which provides (1) a notch filter at a distance between a modulation frequency and a common multiple of commonly used power line frequencies (50, 60, 100 and 120) and also (2) a demodulation frequency greater than a highest pulse rate of a person and lower than any harmonic of 50, 60, 100 or 120 Hz, to filter ambient light interference, while choosing an optimum demodulation frequency that avoids interference from the notch filter or from harmonics of the line interference. Also, ambient light for any low frequency interference, such as power line interference, is measured both before and after each of the light emitter wavelengths and the average of the ambient light is then subtracted from the detected signal.

Abstract translation: 一种脉冲血氧计方法和装置，其提供（1）陷波滤波器，其在调制频率和共同使用的电力线频率（50,60,100和120）的公倍数之间的距离处，以及（2）大于 一个人的最高脉冲频率，低于50,60,100或120Hz的任何谐波，以过滤环境光干扰，同时选择避免陷波滤波器干扰或线干扰谐波的最佳解调频率。 此外，在每个发光体波长之前和之后都测量任何低频干扰（例如电力线干扰）的环境光，然后从检测到的信号中减去环境光的平均值。