公开(公告)号：US20160198965A1

公开(公告)日：2016-07-14

申请号：US14593271

申请日：2015-01-09

Applicant: Xerox Corporation

Inventor： Lalit Keshav MESTHA ,  Martin Edward HOOVER ,  Survi KYAL

IPC: A61B5/024 ,  A61B5/00

CPC classification number: A61B5/02433 ,  A61B5/0013 ,  A61B5/7203 ,  A61B5/7225 ,  A61B5/725 ,  A61B5/748 ,  A61B2576/00

Abstract: What is disclosed is a system and method for selecting a region of interest for extracting physiological parameters from a video of a subject. In one embodiment the present method involves performing the following. First, time-series signals are received which have been generated by having processing image frames of a video of a subject captured using a single band video camera with a bandpass filter with a pass band in a wavelength range of 495-565 nm and/or 800-1000 nm. The regions of interest are areas where a plethysmographic signal can be detected by the camera. Each time-series signal is associated with a different region of interest. A signal strength is then calculated for each of the time-series signals. The region associated with the time-series signal having a highest signal strength is selected. The time-series signal associated with the selected region can be processed to extract a videoplethysmographic (VPG) signal containing physiological parameters.

Abstract translation: 公开的是用于从对象的视频中提取生理参数来选择感兴趣区域的系统和方法。 在一个实施例中，本方法涉及执行以下操作。 首先，通过使用具有带通滤波器的单频带摄像机拍摄的被摄体的视频的处理图像帧在波长范围为495-565nm和/或 800-1000nm。 感兴趣的区域是可以通过照相机检测体积描记信号的区域。 每个时间序列信号与不同的感兴趣区域相关联。 然后为每个时间序列信号计算信号强度。 选择与具有最高信号强度的时间序列信号相关联的区域。 可以处理与所选区域相关联的时间序列信号以提取包含生理参数的视频体积描记（VPG）信号。

公开(公告)号：US20150262338A1

公开(公告)日：2015-09-17

申请号：US14211455

申请日：2014-03-14

Applicant: Xerox Corporation

Inventor： Beilei XU ,  Survi KYAL ,  Lalit Keshav MESTHA ,  Graham S. PENNINGTON

IPC: G06T5/00

CPC classification number: G06T7/20 ,  G06T2207/10016 ,  G06T2207/10024 ,  G06T2207/30076 ,  G06T2207/30088

Abstract: What is disclosed is a system and method for compensating for motion during processing of a video of a subject being monitored for physiological function assessment. In one embodiment, image frames are received. Successive batches of N video frames are processed to isolate pixels associated with a body region of the subject where a physiological signal is registered by the camera. The pixels are processed to obtain a time-series signal for each batch. A determination is made whether movement during video acquisition of this batch of image frames exceeds a threshold level. If so then a size N of the next batch of image frames is changed to: N=N+M1, where N+M1≦Nm. Otherwise, a size N of a next batch is changed to: N=N−M2, where N−M2≧Nmin. Thereafter, processing repeats in a real-time continuous manner as the next batch of the N image frames is received. Various embodiments are disclosed.

Abstract translation: 所公开的是用于在处理被监视的受试者的视频的处理期间补偿运动以进行生理功能评估的系统和方法。 在一个实施例中，接收图像帧。 处理N个视频帧的连续批次以分离与由摄像机登记生理信号的被摄体的身体区域相关联的像素。 处理像素以获得每个批次的时间序列信号。 确定在该批次的图像帧的视频采集期间的移动是否超过阈值水平。 如果是，则下一批图像帧的大小N被改变为：N = N + M1，其中N + M1＆nlE; Nm。 否则，下一批次的大小N变为：N = N-M2，其中N-M2≥Nmin。 此后，当接收到下一批N个图像帧时，处理以实时连续的方式重复。 公开了各种实施例。

公开(公告)号：US20150257661A1

公开(公告)日：2015-09-17

申请号：US14204397

申请日：2014-03-11

Applicant: Xerox Corporation

Inventor： Lalit Keshav MESTHA ,  Survi KYAL

IPC: A61B5/021 ,  A61B5/026 ,  A61B5/00 ,  A61B5/024

CPC classification number: A61B5/02125 ,  A61B5/0015 ,  A61B5/02427 ,  A61B5/0261

Abstract: What is disclosed is a system and method for determining the time it takes for an arterial pulse pressure wave to transit between a proximal and a distal point of a patient's body. In one embodiment, a signal is received from each of a first and second device worn circumferentially around a proximal and a distal region, respectively. The devices are worn on an area of exposed skin. Each of the devices comprises at least one emitter/detector pair fixed to an inner side of each device and has at least one detector paired to at least one illuminator. Each detector has at least one sensor that is sensitive to a wavelength band of light emitted by its illuminator. Each device generates signals that are proportional to an intensity of light emitted by an illuminator. The signals are analyzed to determine arterial pulse wave transit time between the proximal and distal regions.

Abstract translation: 公开的是用于确定动脉脉压压力波在患者身体的近端点和远端点之间转运所花费的时间的系统和方法。 在一个实施例中，从分别围绕近端区域和远端区域周向磨损的第一和第二设备中的每一个接收信号。 设备佩戴在暴露皮肤的一个区域。 每个装置包括固定到每个装置的内侧的至少一个发射器/检测器对，并且具有与至少一个照明器配对的至少一个检测器。 每个检测器具有至少一个对其照射器发出的光的波长带敏感的传感器。 每个设备产生与照明器发射的光的强度成比例的信号。 分析信号以确定近端和远端区域之间的动脉脉搏波传播时间。

公开(公告)号：US20150018693A1

公开(公告)日：2015-01-15

申请号：US13937740

申请日：2013-07-09

Applicant: XEROX CORPORATION

Inventor： Lalit Keshav MESTHA ,  Survi KYAL ,  Barry P. MANDEL ,  Peter Johan NYSTROM

IPC: A61B5/00 ,  A61B5/024

CPC classification number: A61B5/7282 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/02427 ,  A61B5/6831 ,  A61B5/746

Abstract: What is disclosed is a method for monitoring a subject for cardiac arrhythmia such as atrial fibrillation using an apparatus that can be comfortably worn by the subject around an area of exposed skin where a photoplethysmographic (PPG) signal can be registered. In one embodiment, the apparatus is a reflective or transmissive wrist-worn device with emitter/detector pairs fixed to an inner side of a band with at least one illuminator emitting source light at a specified wavelength band. The illuminator is paired to a respective photodetector comprising one or more sensors that are sensitive to a wavelength band of its paired illuminator. The photodetector measures intensity of sensed light emitted by a respective illuminator. The signal obtained by the sensors comprises a continuous PPG signal. The continuous PPG signal analyzed for peak-to-peak pulse points from which the existence of cardiac arrhythmia such as atrial fibrillation event can be determined.

Abstract translation: 所公开的是用于使用可以被注射在光体积描记术（PPM）信号的暴露皮肤区域周围的受试者舒适佩戴的装置来监测心律失常的受试者的心律失常的方法，例如心房颤动。 在一个实施例中，该装置是具有发射器/检测器对的反射或透射腕部装置，其固定到带的内侧，其中至少一个照明器发射指定波长带的光源。 照明器与包括对其成对照明器的波长带敏感的一个或多个传感器的相应光电检测器配对。 光电检测器测量由相应照明器发射的感测光的强度。 由传感器获得的信号包括连续的PPG信号。 分析连续的PPG信号，从中可以确定心律失常如心房颤动事件的存在的峰 - 峰脉冲点。

公开(公告)号：US20140376789A1

公开(公告)日：2014-12-25

申请号：US13923612

申请日：2013-06-21

Applicant: Xerox Corporation

Inventor： Beilei XU ,  Lalit Keshav MESTHA ,  Survi KYAL ,  Himanshu J. MADHU

IPC: G06T7/00 ,  G06T5/00

CPC classification number: G06T5/003 ,  G06T5/50 ,  G06T7/0016 ,  G06T2207/10016 ,  G06T2207/20201 ,  G06T2207/30088

Abstract: What is disclosed is a system for compensating for motion induced artifacts in a physiological signal obtained from multiple videos of a first and second region of interest a subject being monitored for a desired physiological function. At least one of the videos being of the first region and at least one of the videos being of the second region. The first region being at least one area of exposed skin where a desired signal corresponding to the physiological function can be registered by a video imaging device. The second region being an area where a movement by the subject is likely to induce motion artifacts into the signal. The videos are processed to isolate pixels associated with the first and second regions. Processed pixels of the isolated first regions to obtain a composite time-series signal. From the composite signal, a physiological signal corresponding to the physiological function is extracted.

Abstract translation: 所公开的是一种用于补偿从受感染的第一和第二感兴趣区域的多个视频获得的生理信号中的运动诱发伪影的系统，该对象被监视为期望的生理功能。 至少一个视频是第一区域，并且至少一个视频是第二区域。 第一区域是暴露皮肤的至少一个区域，其中对应于生理功能的期望信号可由视频成像装置登记。 第二区域是被摄体的移动可能引起运动伪像进入信号的区域。 处理视频以分离与第一和第二区域相关联的像素。 隔离的第一区域的处理像素以获得复合时间序列信号。 从复合信号中提取与生理功能对应的生理信号。

公开(公告)号：US20140376788A1

公开(公告)日：2014-12-25

申请号：US13923588

申请日：2013-06-21

Applicant: Xerox Corporation

Inventor： Beilei XU ,  Lalit Keshav MESTHA ,  Survi KYAL ,  Himanshu J. MADHU

IPC: G06T5/00

CPC classification number: G06T5/50 ,  G06T5/003 ,  G06T2207/10016 ,  G06T2207/10024 ,  G06T2207/20201 ,  G06T2207/30088

Abstract: What is disclosed is a system and method for compensating for motion induce artifacts in a physiological signal obtained from a video. In one embodiment, a video of a first and second region of interest of a subject being monitored for a desired physiological function is captured by a video device. The first region is an area of exposed skin wherein a desired signal corresponding to the physiological function can be registered. The second region is an area where movement is likely to induce motion artifacts into that signal. The video is processed to isolate pixels in the image frames associated with these regions. Pixels of the first region are processed to obtain a time-series signal. A physiological signal is extracted from the time-series signal. Pixels of the second region are analyzed to identify motion. The physiological signal is processed to compensate for the identified motion.

Abstract translation: 所公开的是用于补偿从视频获得的生理信号中的运动诱发伪影的系统和方法。 在一个实施例中，由视频设备捕获被监视用于期望生理功能的被摄体的第一和第二感兴趣区域的视频。 第一区域是暴露皮肤的区域，其中可以登记对应于生理功能的期望信号。 第二区域是运动可能引起运动伪影成该信号的区域。 处理视频以隔离与这些区域相关联的图像帧中的像素。 处理第一区域的像素以获得时间序列信号。 从时间序列信号中提取生理信号。 分析第二区域的像素以识别运动。 处理生理信号以补偿所识别的运动。

公开(公告)号：US20140160355A1

公开(公告)日：2014-06-12

申请号：US13708125

申请日：2012-12-07

Applicant: XEROX CORPORATION

Inventor： Lalit Keshav MESTHA ,  Survi KYAL ,  Sohail A. DIANAT

IPC: H04N5/14

CPC classification number: G06T3/4007 ,  G06T3/4053 ,  H04N7/01 ,  H04N7/0135

Abstract: What is disclosed is a novel video processing system and method wherein a plurality of image frames of a video captured using a video camera with a spatial resolution of (M×N) in the (x, y) direction, respectively, and a temporal resolution (T) in frames per unit of time. A first and second magnification factor f1, f2 are selected for spatial enhancement in the (x, y) direction. A third magnification factor f3 is selected for a desired temporal enhancement in (T). The video data is processed using a dictionary comprising high and low resolution patch cubes which are used to induce spatial and temporal components in the video where no data exists. A high resolution course video X0 is generated which has an enhanced spatial resolution of (f1* M)×(f2*N) and an enhanced temporal resolution of (f3*T) frames. The course high resolution video is then smoothed, when found required, to generate a smoothed high resolution video.

Abstract translation: 所公开的是一种新颖的视频处理系统和方法，其中使用在（x，y）方向上具有（M×N）的空间分辨率的摄像机捕获的视频的多个图像帧分别为（x，y） （T）以每单位时间的帧为单位。 选择第一和第二放大因子f1，f2用于（x，y）方向上的空间增强。 在（T）中为期望的时间增强选择第三放大因子f3。 使用包括高分辨率和低分辨率片段立方体的字典来处理视频数据，这些立方体用于在没有数据存在的视频中诱导空间和时间分量。 产生具有（f1 * M）×（f2 * N）的增强的空间分辨率和（f3 * T）帧的增强的时间分辨率的高分辨率过程视频X0。 当高分辨率视频被发现时需要平滑化，以产生平滑的高分辨率视频。

公开(公告)号：US20150313502A1

公开(公告)日：2015-11-05

申请号：US14268656

申请日：2014-05-02

Applicant: XEROX CORPORATION

Inventor： Lalit Keshav MESTHA ,  Survi KYAL

IPC: A61B5/0452 ,  A61B5/117 ,  A61B5/00 ,  A61B5/0265 ,  A61B5/021 ,  A61B5/0295 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/02

CPC classification number: A61B5/04525 ,  A61B5/0006 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0077 ,  A61B5/02007 ,  A61B5/0205 ,  A61B5/02125 ,  A61B5/02416 ,  A61B5/02433 ,  A61B5/0245 ,  A61B5/0261 ,  A61B5/0265 ,  A61B5/0295 ,  A61B5/0402 ,  A61B5/1176 ,  A61B5/6898 ,  A61B5/7207 ,  A61B2560/0475 ,  A61B2576/00

Abstract: What is disclosed is a system and method for determining arterial pulse wave transit time for a subject. In one embodiment, a video is received comprising a plurality of time-sequential image frames of a region of exposed skin of a subject where a videoplethysmographic (VPG) signal can be registered by at least one imaging channel of the video device used to capture that video. Also received is an electrocardiogram (ECG) signal obtained using at least one sensor placed on the subject's body where a ECG signal can be obtained. Batches of image frames are processed to obtain a continuous VPG signal for the subject. Temporally overlapping VPG and ECG signals are analyzed to obtain a pulse wave transit time between a reference point on the VPG signal and a reference point on the ECG signal. The pulse transit time is used to assess pathologic conditions such as peripheral vascular disease.

Abstract translation: 公开的是用于确定受试者的动脉脉搏波传播时间的系统和方法。 在一个实施例中，接收视频，其包括受试者暴露皮肤区域的多个时间顺序图像帧，其中视频体积描记（VPG）信号可由用于捕获该视频信号的视频设备的至少一个成像通道注册 视频。 还接收了使用放置在被检体的身体上的至少一个传感器获得的心电图（ECG）信号，其中可以获得ECG信号。 处理批量的图像帧以获得对象的连续VPG信号。 分析时间重叠的VPG和ECG信号，以获得VPG信号上的参考点与ECG信号上的参考点之间的脉搏波传播时间。 脉冲传播时间用于评估外周血管疾病等病理状况。

公开(公告)号：US20150272456A1

公开(公告)日：2015-10-01

申请号：US14242322

申请日：2014-04-01

Applicant: Xerox Corporation

Inventor： Survi KYAL ,  Lalit Keshav MESTHA ,  Jean-Philippe COUDERC

IPC: A61B5/024 ,  A61B5/00

CPC classification number: A61B5/0077 ,  A61B5/0082 ,  A61B5/0295 ,  A61B5/1073

Abstract: What is disclosed is a system and method for determining whether a subject is in atrial fibrillation. A video is received of a region of exposed skin of a subject. The video is acquired of a region where a videoplethysmographic (VPG) signal can be registered by at least one imaging channel of a video imaging device. For each batch of image frames, pixels associated with the region of exposed skin are isolated and processed to obtain a time-series signal. A VPG signal is extracted from the time-series signal. The power spectral density (PSD) is computed across all frequencies within the VPG signal. A pulse harmonic strength (PHS) is calculated for this VPG signal. The pulse harmonic strength is compared to a discrimination threshold, defined herein. A determination is made whether the subject in the video is in atrial fibrillation or in normal sinus rhythm.

Abstract translation: 公开的是用于确定受试者是否在心房颤动中的系统和方法。 收到受试者暴露皮肤区域的视频。 获取视频体积描记（VPG）信号的区域可以由视频成像设备的至少一个成像通道注册的视频。 对于每批图像帧，与暴露皮肤区域相关联的像素被隔离并处理以获得时间序列信号。 从时间序列信号中提取VPG信号。 在VPG信号内的所有频率上计算功率谱密度（PSD）。 为该VPG信号计算脉冲谐波强度（PHS）。 将脉冲谐波强度与本文定义的鉴别阈值进行比较。 视频中的主体是否处于心房颤动或正常窦性心律中。

公开(公告)号：US20150245787A1

公开(公告)日：2015-09-03

申请号：US14195111

申请日：2014-03-03

Applicant: Xerox Corporation

Inventor： Survi KYAL ,  Lalit Keshav MESTHA ,  Himanshu J. MADHU

IPC: A61B5/08 ,  H04N5/357 ,  A61B5/00 ,  H04N7/18

CPC classification number: A61B5/1135 ,  A61B5/1128

Abstract: What is disclosed is a system and method for processing a video for respiratory function analysis. In one embodiment, a video is received of a region of the subject's body where a time-varying signal corresponding to the subject's respiration can be registered by the video camera. Pixels in a first batch of frames are processed to obtain a time-series signal which is filtered using a band-pass filter with a low and high cutoff frequency fL and fH, where fL and fH are a function of the subject's tidal breathing. The filtered time-series signal is analyzed to identify a next low and high cutoff frequency f′L and F′H, where fL

Abstract translation: 公开的是用于处理用于呼吸功能分析的视频的系统和方法。 在一个实施例中，接收到被摄体的身体的区域的视频，其中对应于被摄体的呼吸的时变信号可由摄像机注册。 处理第一批帧中的像素以获得使用具有低和高截止频率fL和fH的带通滤波器进行滤波的时间序列信号，其中fL和fH是受试者的潮气呼吸的函数。 分析滤波后的时间序列信号，以识别下一个低和高截止频率f'L和F'H，其中fL