公开(公告)号：US09133497B2

公开(公告)日：2015-09-15

申请号：US14611902

申请日：2015-02-02

Applicant: GeneWeave Biosciences, Inc.

Inventor： Werner Frei ,  Diego Ariel Rey ,  Shaunak Roy ,  Ryan C. Griswold ,  Kenneth G. Olson ,  Bruce J. Richardson ,  Rick V. Stellmacher

IPC: G01N21/13 ,  G01N21/15 ,  G01N21/17 ,  C12Q1/04 ,  B01L3/00 ,  G01N21/01 ,  G01N21/76 ,  G01N21/03 ,  C12Q1/68 ,  B01L7/00 ,  C12Q1/02 ,  G01J1/00 ,  C12Q1/66 ,  G01N35/00 ,  G01N35/04

CPC classification number: C12Q1/6897 ,  B01L3/502 ,  B01L3/50825 ,  B01L3/52 ,  B01L3/523 ,  B01L3/54 ,  B01L3/545 ,  B01L7/00 ,  B01L2200/028 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/042 ,  B01L2300/047 ,  B01L2300/049 ,  B01L2300/0672 ,  B01L2400/0478 ,  B01L2400/06 ,  B01L2400/0683 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/06 ,  C12Q1/10 ,  C12Q1/14 ,  C12Q1/66 ,  G01J1/00 ,  G01N21/01 ,  G01N21/03 ,  G01N21/13 ,  G01N21/76 ,  G01N21/763 ,  G01N2035/00346 ,  G01N2035/0405 ,  G01N2333/195

Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.

Abstract translation: 本文描述了使用工程化转导颗粒检测和/或鉴定靶细胞（例如细菌）的系统和方法。 在一些实施方案中，一种方法包括将一定量的转导颗粒混合在样品内。 转导颗粒与靶细胞相关联。 转导颗粒是非复制型的，并被工程化以包括配制成使靶细胞产生一系列报道分子的核酸分子。 当靶细胞存在于样品中时，保持样品和转导颗粒以表达一系列报告分子。 接收与一定量的报道分子相关的信号。 在一些实施例中，信号的幅度与高于预定量的转导颗粒的数量无关。

公开(公告)号：US20150146970A1

公开(公告)日：2015-05-28

申请号：US14088615

申请日：2013-11-25

Applicant: International Business Machines Corporation

Inventor： John F. Kelley ,  Douglas E. Lhotka ,  Kristin S. Moore ,  Todd P. Seager

IPC: G06T7/00 ,  G06T7/40

CPC classification number: G06K9/4661 ,  G01J1/00 ,  G06K9/4604 ,  G06K9/4652 ,  G06K2009/4666 ,  G06T7/11 ,  G06T7/13 ,  G06T7/90 ,  H04N13/20

Abstract: A method for capturing three-dimensional photographic lighting of a spherical lighting device is described. Calculation of boundaries of the spherical lighting device based on lighting properties of at least one light source in a set location of the spherical lighting device is performed. A mapping of multitude points of the spherical lighting device to three-dimensional vectors of at least one camera device using a logical grid is performed. A measurement of brightness of the logical grid of the spherical lighting device is performed. The method further comprises determining brightest grid point of the logical grid of the spherical lighting device, wherein the brightest grid point of the logical grid is measured within a region brightness of the spherical lighting device. The method further comprises calculating the region of brightness of the spherical lighting device based on the determined brightest grid point of the logical grid.

Abstract translation: 描述了一种用于捕获球形照明装置的三维摄影照明的方法。 执行基于球面照明装置的设定位置中的至少一个光源的照明特性的球面照明装置的边界的计算。 执行球形照明装置的多个点与使用逻辑网格的至少一个相机装置的三维向量的映射。 执行球面照明装置的逻辑网格的亮度的测量。 该方法还包括确定球形照明装置的逻辑网格的最亮格网点，其中在球形照明装置的区域亮度内测量逻辑网格的最亮格网点。 该方法还包括基于确定的逻辑网格的最亮网格点来计算球形照明装置的亮度区域。

公开(公告)号：US20150117855A1

公开(公告)日：2015-04-30

申请号：US14510352

申请日：2014-10-09

Applicant: HON HAI PRECISION INDUSTRY CO., LTD.

Inventor： CHANG-WEI KUO

IPC: H04B10/079

CPC classification number: G01J1/00 ,  H04B10/0731

Abstract: An optical subassembly testing system includes a pedestal, a rotation device, a holder and a supporting device. The rotation device includes a rotation member, a connecting plate and a retractable pillar. The rotation member is arranged on the pedestal and rotates relative to the pedestal. The connecting plate includes a mounting portion and a protruding portion, the mounting portion is arranged on the rotation member, the protruding portion extends away from the mounting portion and is exposed outside of the rotation member, and the retractable pillar is fixed perpendicular to the pedestal on an end of the protruding portion. The holder is fixed on an end of the retractable pillar and clamps a fiber connector. The supporting device includes a plurality of receiving grooves surrounding the pedestal, the receiving grooves are configured for receiving transmitter optical subassemblies (TOSAs) to test by aligning the fiber connector with each TOSA in turn.

Abstract translation: 光学子组件测试系统包括基座，旋转装置，支架和支撑装置。 旋转装置包括旋转构件，连接板和可缩回支柱。 旋转构件布置在基座上并相对于基座旋转。 所述连接板包括安装部和突出部，所述安装部配置在所述旋转部件上，所述突出部远离所述安装部延伸，露出在所述旋转部件的外侧，所述伸缩支柱与所述基座 在突出部分的一端。 支架固定在可伸缩支柱的一端并夹住光纤连接器。 所述支撑装置包括围绕所述基座的多个接收槽，所述接收槽构造成用于接收发射器光学子组件（TOSA），以依次对准所述光纤连接器与每个TOSA进行测试。

公开(公告)号：US20140362368A1

公开(公告)日：2014-12-11

申请号：US14290288

申请日：2014-05-29

Applicant: Sony Corporation

Inventor： Koji Kikuchi

IPC: G02B7/28

CPC classification number: H04N5/23212 ,  G01J1/00 ,  G02B3/0043 ,  G02B27/285 ,  H01L27/14607 ,  H01L27/14623 ,  H01L27/14627 ,  H01L27/14629 ,  H01L27/14643 ,  H01L27/14685 ,  H01L27/14687

Abstract: There is provided a focus detection apparatus including: microlenses; light reception units that receive light which is incident through the microlenses; waveguides that cause light, which is incident to the microlenses at a predetermined angle, to be received by the light reception units and that are provided between the microlenses and the light reception units; and a detection unit that detects focusing output values from the light reception units.

Abstract translation: 提供了一种聚焦检测装置，包括：微透镜; 接收通过微透镜入射的光的光接收单元; 导入光以预定角度入射到微透镜的光的波导由光接收单元接收并且设置在微透镜和光接收单元之间; 以及检测单元，其检测来自所述光接收单元的聚焦输出值。

公开(公告)号：US20140117858A1

公开(公告)日：2014-05-01

申请号：US13803967

申请日：2013-03-14

Applicant: Donald H. Jacobs

Inventor： Donald H. Jacobs

IPC: H05B37/02 ,  G01J1/00

CPC classification number: G01J1/00 ,  H05B37/0218 ,  Y02B20/46

Abstract: A method of estimating the occurrence of midnight on a given day comprises the steps of determining the average night length (NLAVE) by averaging the night lengths (NL) between a night starting time (NST) as determined by a photosensor and a night ending time (NET) determined by a photosensor for each of a plurality of days, and estimating midnight to occur at the time that is one half of the average night length (NLAVE) after the night starting time (NST) for the given day. This estimate of midnight to control the operation of lights or other equipment without the need for clocks or constant power.

Abstract translation: 估计给定日期的午夜发生的方法包括以下步骤：通过平均夜间起始时间（NST）之间的平均夜晚长度（N N）来确定平均夜晚长度（NLAVE） （NET），并且估计在当天的晚上开始时间（NST）之后的平均夜晚长度（NLAVE）的一半的时间发生的午夜。 这个估计是为了控制灯光或其他设备的操作而不需要时钟或恒定电源。

公开(公告)号：US20140063490A1

公开(公告)日：2014-03-06

申请号：US14010484

申请日：2013-08-26

Applicant: KLA-Tencor Corporation

Inventor： Qiang Zhang ,  Yanwei Liu ,  Abdurrahman Sezginer

IPC: G01J1/42

CPC classification number: G01J1/00 ,  G01J1/4257 ,  G02B5/0833 ,  G02B5/0891 ,  G03F1/24 ,  G03F1/50 ,  G03F1/52 ,  G03F1/84 ,  G21K7/00

Abstract: Disclosed is test structure for measuring wave-front aberration of an extreme ultraviolet (EUV) inspection system. The test structure includes a substrate formed from a material having substantially no reflectivity for EUV light and a multilayer (ML) stack portion, such as a pillar, formed on the substrate and comprising a plurality of alternating pairs of layers having different refractive indexes so as to reflect EUV light. The pairs have a count equal to or less than 15.

Abstract translation: 公开了用于测量极紫外（EUV）检测系统的波前像差的测试结构。 测试结构包括由基本上不对EUV光反射的材料形成的基板和形成在基板上的多层（ML）堆叠部分，例如柱状物，并且包括具有不同折射率的多个交替对的层， 反映EUV光。 这些对具有等于或小于15的计数。

公开(公告)号：US20130141714A1

公开(公告)日：2013-06-06

申请号：US13669751

申请日：2012-11-06

Applicant: SAMSUNG DISPLAY CO., LTD.

Inventor： Jung-In PARK ,  Cha-Dong KIM ,  Su-Yeon SIM ,  Sang-Hyun YUN ,  Hi-Kuk LEE

IPC: G01J1/00

CPC classification number: G01J1/00 ,  G03F7/20 ,  G03F7/70133

Abstract: An exposure system includes an exposure apparatus, a mask, a test pattern portion and a uniformity measuring part. The exposure apparatus includes a first module and a second module. The first and second modules each emit light and are overlapped in an overlapping area. The mask includes a plurality of transmission portions which are spaced apart from each other. Each of the transmission portions has a width less than a width of the overlapping area. The test pattern portion includes a plurality of test patterns which are patterned by using the light transmitted through the transmission portions of the mask. The uniformity measuring part measures a uniformity of the test patterns.

Abstract translation: 曝光系统包括曝光装置，掩模，测试图案部分和均匀度测量部分。 曝光装置包括第一模块和第二模块。 第一和第二模块各自发光并且在重叠区域中重叠。 掩模包括彼此间隔开的多个传输部分。 每个传输部分具有小于重叠区域的宽度的宽度。 测试图形部分包括通过使用透过掩模的透射部分的光而构图的多个测试图案。 均匀度测量部件测量测试图案的均匀性。

公开(公告)号：US07960700B2

公开(公告)日：2011-06-14

申请号：US11541341

申请日：2006-09-29

Applicant: William W. Craig ,  Simon E. Labov

Inventor： William W. Craig ,  Simon E. Labov

IPC: G01T1/24

CPC classification number: G01J1/00 ,  G01T1/026 ,  G01T7/00

Abstract: A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.

Abstract translation: 辐射检测仪器网络，每个都具有集成到蜂窝电话中的小型固体辐射传感器模块，用于直接向用户提供辐射检测数据和分析。 传感器模块包括结合到ASIC读数的固态晶体，其提供低成本，低功率，重量轻的紧凑型仪器，以检测和测量局部环境辐射场中的辐射能量。 特别地，记录光电子能量，事件时间和检测仪器在检测时的位置，以实时传输到中央数据采集/分析系统。 来自整个辐射检测仪器网络的数据通过智能相关/分析算法相结合，绘制了背景辐射，检测，识别和跟踪该地区的辐射异常。

公开(公告)号：US20070018806A1

公开(公告)日：2007-01-25

申请号：US11540176

申请日：2006-09-29

Applicant: William Craig ,  Simon Labov

Inventor： William Craig ,  Simon Labov

IPC: G08B23/00

CPC classification number: G01J1/00 ,  G01T1/026 ,  G01T7/00

Abstract: A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.

Abstract translation: 辐射检测仪器网络，每个都具有集成到蜂窝电话中的小型固体辐射传感器模块，用于直接向用户提供辐射检测数据和分析。 传感器模块包括结合到ASIC读数的固态晶体，其提供低成本，低功率，重量轻的紧凑型仪器，以检测和测量局部环境辐射场中的辐射能量。 特别地，记录光电子能量，事件时间和检测仪器在检测时的位置，以实时传输到中央数据采集/分析系统。 来自整个辐射检测仪器网络的数据通过智能相关/分析算法相结合，绘制了背景辐射，检测，识别和跟踪该地区的辐射异常。

公开(公告)号：US07142634B2

公开(公告)日：2006-11-28

申请号：US10767024

申请日：2004-01-29

Applicant: Mark J. Engler ,  Mark J. Rivard

Inventor： Mark J. Engler ,  Mark J. Rivard

IPC: A61N5/10

CPC classification number: G01T1/169 ,  A61N5/1042 ,  A61N5/1047 ,  A61N5/1048 ,  A61N5/1075 ,  A61N5/1084 ,  A61N2005/1076 ,  G01J1/00 ,  G01T1/185

Abstract: A radiation field detection system, for use with a radiating device, includes a radiation detector configured to receive radiation and to provide radiation strength indicia of amounts of radiation received, a positioning mechanism connected to the radiation detector and configured to physically move the radiation detector, and a processor coupled to the positioning mechanism and coupled to the radiation detector to receive the radiation strength indicia, the processor being configured to: actuate the positioning mechanism to move the radiation detector to desired locations within a radiation field produced by the radiating device; analyze the radiation strength indicia from the radiation detector; correlate positions of the radiation detector with corresponding amounts of received radiation; determine a first location of maximum detected radiation; and determine a first relationship between the first location of maximum detected radiation and a second location of maximum radiation.

Abstract translation: 用于与辐射装置一起使用的辐射场检测系统包括：辐射检测器，被配置为接收辐射并提供接收的辐射量的辐射强度标记;连接到辐射检测器并被配置为物理地移动辐射检测器的定位机构， 以及处理器，其耦合到所述定位机构并且耦合到所述辐射检测器以接收所述辐射强度标记，所述处理器被配置为：致动所述定位机构以将所述辐射检测器移动到由所述辐射装置产生的辐射场内的期望位置; 分析辐射检测器的辐射强度标记; 将辐射探测器的位置与相应的接收辐射量相关联; 确定最大检测辐射的第一位置; 并且确定最大检测到的辐射的第一位置与最大辐射的第二位置之间的第一关系。