公开(公告)号：US20170135584A1

公开(公告)日：2017-05-18

申请号：US15359279

申请日：2016-11-22

Applicant: The General Hospital Corporation ,  Boston University

Inventor： Guillermo J. Tearney ,  Brett Eugene Bouma ,  Hongki Yoo ,  Milen Shishkov ,  Joseph Gardecki ,  Roman Shubochkin ,  Theodore Morse ,  Farouc Amin Jaffer

IPC: A61B5/00 ,  G01B9/02 ,  G01N21/65 ,  G01N21/64

CPC classification number: A61B5/0084 ,  A61B5/0066 ,  A61B5/0071 ,  A61B5/6852 ,  G01B9/02029 ,  G01B9/0205 ,  G01B9/02091 ,  G01N21/4795 ,  G01N21/64 ,  G01N21/6456 ,  G01N21/65 ,  G01N2201/0866

Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.

公开(公告)号：US20120101374A1

公开(公告)日：2012-04-26

申请号：US13114845

申请日：2011-05-24

Applicant: Guillermo J. Tearney ,  Brett Eugene Bouma ,  Hongki Yoo ,  Milen Shishkov ,  Joseph Gardecki ,  Roman Shubochkin ,  Theodore Morse ,  Farouc Amin Jaffer

Inventor： Guillermo J. Tearney ,  Brett Eugene Bouma ,  Hongki Yoo ,  Milen Shishkov ,  Joseph Gardecki ,  Roman Shubochkin ,  Theodore Morse ,  Farouc Amin Jaffer

IPC: A61B6/00

CPC classification number: A61B5/0084 ,  A61B5/0066 ,  A61B5/0071 ,  A61B5/6852 ,  G01B9/02029 ,  G01B9/0205 ,  G01B9/02091 ,  G01N21/4795 ,  G01N21/64 ,  G01N21/6456 ,  G01N21/65 ,  G01N2201/0866

Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.

Abstract translation: 描述了用于提供和/或利用光学频域成像（OFDI）和结构荧光以及例如使用OFDI技术和荧光成像技术的多模态成像的示例性系统，装置，方法，装置和计算机可访问介质。 例如，一种布置可以向解剖结构提供至少一个电磁辐射。 这种示例性布置可以包括至少一个光学芯和至少部分围绕光纤的至少一个包层。 光纤芯和包层之间的区域可以具有与光纤芯和包层的折射率不同的折射率。 该装置还可以包括至少一个被配置成经由光学核和包层传播辐射到解剖结构的装置。

公开(公告)号：US5307146A

公开(公告)日：1994-04-26

申请号：US962394

申请日：1992-10-16

Applicant: Marc D. Porter ,  Thomas P. Jones ,  Shelley J. Coldiron

Inventor： Marc D. Porter ,  Thomas P. Jones ,  Shelley J. Coldiron

IPC: G01N21/27 ,  G01J1/16 ,  G01N21/31 ,  G01N21/77 ,  G01N21/80 ,  G01J3/427

CPC classification number: G01N21/7703 ,  G01J2001/1636 ,  G01N2021/3181 ,  G01N2021/772 ,  G01N21/80 ,  G01N2201/062 ,  G01N2201/084 ,  G01N2201/0866

Abstract: A dual wavelength optical sensor for measuring chemical properties of a particular quantity, the optical sensor including a sensor probe having a thin sensing film whose optical characteristics are responsive to the chemical properties of the measured quantityThe United States Government has certain rights in this invention pursuant to Contract No. ITA87-02 between the U.S. Department of Commerce and Iowa State University.

Abstract translation: 一种用于测量特定量的化学性质的双波长光学传感器，所述光学传感器包括具有薄的感测膜的传感器探针，所述传感器探针的光学特性响应于所述测量量在至少两个不同波长的光的化学特性 当对至少两个不同波长的响应进行组合时，提供了测量的化学性质的自校准测量。 光源产生至少两个不同波长的光，并且单个光纤将来自光源的光传送到传感器探针。 样品检测器在传感器探头经过薄膜感测膜并从薄膜传感器接收来自传感器探针的光，并产生至少两个不同波长的光的光强度读数。 光学传感器还包括用于组合来自样本检测器的光强度读数的信号处理系统，以产生自校准的测量，其考虑到薄传感膜的光学特性的变化，否则这将有助于传感器响应中的不稳定性。