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公开(公告)号：US20150005739A1
公开(公告)日：2015-01-01
申请号：US14296109
申请日：2014-06-04
Applicant: Worcester Polytechnic Institute
Inventor： Glenn Gaudette , George D. Pins , Marsha Rolle , Jacques P. Guyette , Kevin Cornwall
CPC classification number: A61L31/046 , A61B17/0469 , A61B17/06 , A61B17/06166 , A61B2017/00243 , A61B2017/00893 , A61L27/225 , A61L27/3826 , A61L27/3834 , A61L27/3873 , A61L31/16 , A61L2430/20 , C12N5/0068 , C12N11/02 , C12N2533/56
Abstract: Compositions that include microthreads are provided. The compositions can be fully or partially encased in a sleeve along at least a portion of their length and can include biological cells and, optionally, therapeutic agents. Also provided are methods for using the compositions to repair or ameliorate damaged or defective tissue, including cardiovascular tissue (e.g., the myocardium).
Abstract translation: 提供包括微丝的组合。 组合物可以沿其长度的至少一部分完全或部分地包封在套管中，并且可以包括生物细胞和任选的治疗剂。 还提供了使用组合物来修复或改善包括心血管组织（例如心肌）的损伤或缺陷组织的方法。
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公开(公告)号：US20140222746A1
公开(公告)日：2014-08-07
申请号：US14167215
申请日：2014-01-29
Applicant: Worcester Polytechnic Institute
Inventor： Janice D. Gobert , Ryan S. Baker , Michael A. Sao Pedro
IPC: G06N5/02
CPC classification number: G09B19/00 , G06N5/022 , G06N5/025 , G06Q10/06398 , G09B5/00 , G09B5/02 , G09B7/02
Abstract: An assessment engine includes a definition of inquiry skills being assessed. Assessment models are used to infer skill demonstration as one or more students engage in inquiry within computerized simulations and/or microworlds. A pedagogical agent and/or help system provides real-time feedback to one or more students based on the assessment model outputs, and/or based on additional models that track one or more students developing proficiency across inquiry tasks over time. A pedagogical agent and/or help system for science inquiry tutoring responds in real-time on the basis of knowledge-engineered and data-mined assessment and/or tracking models.
Abstract translation: 评估引擎包括正在评估的查询技能的定义。 评估模型用于推测技能演示，因为一个或多个学生在计算机化模拟和/或微世界中进行查询。 教学代理和/或帮助系统基于评估模型输出，和/或基于跟踪一个或多个学生在一段时间内跨查询任务熟练度的附加模型来向一个或多个学生提供实时反馈。 用于科学咨询辅导的教学代理和/或帮助系统在知识设计和数据挖掘评估和/或跟踪模型的基础上实时响应。
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公开(公告)号：US20130226845A1
公开(公告)日：2013-08-29
申请号：US13774981
申请日：2013-02-22
Applicant: WORCESTER POLYTECHNIC INSTITUTE
Inventor： Janice D. Gobert , Ermal Toto
IPC: G06N99/00
CPC classification number: G06N99/005 , G06F3/013 , G09B5/02 , G09B7/04 , G09B19/00 , G09B19/0069
Abstract: A digital instructional environment leverages an infrared eye-tracker to monitor a learner's reading and viewing of text and simulations for subject matter. The system detects out-of-order reading/viewing patterns that could lead to poor comprehension. The digital learning environment communicates with other tutorial components including simulation environments, pedagogical agents and may respond in real-time to such patterns with messages that guide learners (knowledge acquirers) to return to effective reading/viewing patterns so as to promote effective construction of mental model(s) developed during knowledge acquisition/learning.
Abstract translation: 数字教学环境利用红外眼睛跟踪器监视学习者的阅读和观看文本以及主题的模拟。 系统检测到可能导致理解差的无序阅读/查看模式。 数字学习环境与其他辅导组件（包括模拟环境，教学代理）进行通信，并且可以通过引导学习者（知识获取者）返回到有效的阅读/观看模式的消息来实时地回应这样的模式，以促进精神上的有效构建 在知识获取/学习过程中开发的模型。
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公开(公告)号：US20130144180A1
公开(公告)日：2013-06-06
申请号：US13684979
申请日：2012-11-26
Applicant: Worcester Polytechnic Institute
Inventor： Ki H. Chon , Jinseok Lee
IPC: A61B5/046 , A61B5/04 , A61B5/0456
CPC classification number: A61B5/046 , A61B5/04012 , A61B5/0456
Abstract: Methods and systems for automatic detection of Atrial Fibrillation (AF) are disclosed. The methods and systems use time-varying coherence functions (TVCF) to detect AF. The TVCF is estimated by the multiplication of two time-varying transfer functions (TVTFs).
Abstract translation: 公开了自动检测心房颤动（AF）的方法和系统。 方法和系统使用时变相干函数（TVCF）来检测AF。 TVCF通过两个时变传递函数（TVTF）的乘法来估计。
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公开(公告)号：US20250164327A1
公开(公告)日：2025-05-22
申请号：US18955546
申请日：2024-11-21
Applicant: Worcester Polytechnic Institute
Inventor： Pratap Rao , Ritwik Pandey , Markus P. Nemitz
Abstract: A flexible sensor invokes a fluid sensing medium in an encapsulation for detecting pressure based on movement of the fluid in the flexible encapsulation. The fluid sensing medium is a conductive liquid which exhibits a varied resistance to changes in a cross section resulting from deformation of the flexible encapsulation. A flexible substrate with a fused planar material adheres around the fluid sensing medium. The fluid sensing medium maty be deposited or placed by an extrusion or print nozzle, a screen or other selective application. A deposited bead or run of the fluid sensing medium has a viscosity for holding a shape until the flexible planar material is adhered. A narrow, elongated and patterned or curved run provides a length of encapsulated fluid which is responsive to deformation from pressure. Insertion of electrical leads at opposed ends of the run provides a measurable electrical resistance that varies with fluid movement.
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Patent Agency Ranking
公开(公告)号：US20250160799A1
公开(公告)日：2025-05-22
申请号：US18955638
申请日：2024-11-21
Applicant: Worcester Polytechnic Institute
Inventor： Abdulsalam Almadani , Emmanuel Agu , Abhishek Shivdeo , Atifa Sarwar , Jacques Kpodonu , Monica Ahluwalia
Abstract: A cardiovascular analysis application receives patient echocardiograms as video segments and performs an analysis for cardiovascular health based on factors related to an ejection fraction and hypertrophic cardiomyopathy based on the images in the video segment and spatiotemporal features extracted from the images through several heartbeat cycles on the video segments. The models are trained on a corpus of previous echocardiograms including labels indicative of the ejection fraction and physiological markers associated with HCM, such as the cardiac wall thickness and clarity. Based on a correspondence with the model, a result is rendered indicative of whether the patient video segment has an insufficient ejection fraction and whether a presence of HCM is exhibited.
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公开(公告)号：US20250137094A1
公开(公告)日：2025-05-01
申请号：US18934545
申请日：2024-11-01
Applicant: Worcester Polytechnic Institute
Inventor： Himanshu Tanvar , Brajendra Mishra
Abstract: Niobium and tantalum extraction industries heavily depend on fluoride chemistry for metal oxide production. A fluoride-free approach utilizes alkali treatment for selective dissolution of niobium and tantalum phases. The application of microwave heating in the alkali treatment of columbite significantly reduced the processing time, providing a higher reaction rate and recovery than furnace or convection heating. Purified oxides are recovered using either direct precipitation or solvent extraction.
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公开(公告)号：US20250130162A1
公开(公告)日：2025-04-24
申请号：US18924362
申请日：2024-10-23
Applicant: Worcester Polytechnic Institute
Inventor： Ulkuhan Guler , Tuna B. Tufan , John A. McNeill
Abstract: A wearable, miniaturized wireless device provides accurate measurement of transcutaneous carbon dioxide diffusing though the skin detects a luminescent response of a carbon dioxide-sensitive film, providing an accurate reflection of a person's blood carbon dioxide levels. The device employs a charge-to-digital converter (CDC) architecture operable for implementation of a time-domain dual lifetime referencing computation to measure transcutaneous carbon dioxide. This potential product enables highly accurate and precise measurements of transcutaneous carbon dioxide while minimizing interference from confounding factors.
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公开(公告)号：US12280177B2
公开(公告)日：2025-04-22
申请号：US17388652
申请日：2021-07-29
Applicant: Wisconsin Alumni Research Foundation , ARKANSAS STATE UNIVERSITY—JONESBORO , Worcester Polytechnic Institute
Inventor： William L. Murphy , Gianluca Fontana , Joshua Gershlak , Glenn Gaudette , Pam Weathers , Tanja Dominko , Marsha Rolle , Sarah Hernandez , Carol Cramer , Luis Fabircio Medina-Bolivar , Bernard Binder
Abstract: Decellularized plant tissues and the use of these plant tissues as scaffolds are disclosed herein. Particularly, decellularized plant tissues are functionalized such to allow for human cell adhesion, thereby allowing for their use as scaffolds for human cells. These scaffolds can then be used in a number of applications/markets, including as research tools for tissue engineering, regenerative medicine, and basic cellular biology.
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公开(公告)号：US20250033211A1
公开(公告)日：2025-01-30
申请号：US18787513
申请日：2024-07-29
Applicant: Worcester Polytechnic Institute
Inventor： Sean McGovern , Jing Xiao
Abstract: A generalized approach and methodology for addressing surface traversal and coverage of a 3 Dimensional (3-D) object receives a 3-D wireframe or similar Cartesian based representation, converts the 3-D representation to a u,v system or mapping. Often employed for texture mapping, u.v grid systems define a two dimensional form of an object, often referred to as “unfolding” of an object. Configurations herein define a u.v grid system directly on the 3-D object for computing a coverage path, typically an aggregation of raster passes to traverse an entire 3-D surface. From a robotic manipulator, a 3D freeform surface, and task constraints, the approach determines whether there exists a feasible continuous motion plan to cover the surface, and if so, produces a uniform coverage path that best satisfies task constraints resulting from the physical object and robot kinematics.
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