公开(公告)号：US08068909B2

公开(公告)日：2011-11-29

申请号：US11769402

申请日：2007-06-27

Applicant: Bin Mi ,  Yongxing Zhang ,  Yunlong Zhang ,  James O. Gilkerson

Inventor： Bin Mi ,  Yongxing Zhang ,  Yunlong Zhang ,  James O. Gilkerson

IPC: A61B5/02

CPC classification number: A61N1/056 ,  A61B5/02438 ,  A61B5/02444 ,  A61B5/6846 ,  A61B5/6851 ,  A61N1/36514 ,  A61N1/36578

Abstract: Embodiments of the invention are related to implantable devices including movement sensors and related methods for measuring cardiac performance, amongst other things. In an embodiment, the invention includes an implantable electrical stimulation lead. The electrical stimulation lead can include a lead body having a proximal end and a distal end and a sheath defining a central lumen. The lead body can further include an electrical conductor disposed within the central lumen of the sheath. The stimulation lead can further include a stimulation electrode positioned at the distal end of the lead body, the stimulation electrode in electrical communication with the electrical conductor. The electrical stimulation lead can include an flexion sensor coupled to the lead body, the movement sensor configured to generate a signal in response to movement of the lead body. In an embodiment, the invention includes a method of monitoring the condition of a heart failure patient. In an embodiment, the invention includes a method of treating unstable arrhythmia in a patient. Other embodiments are also included herein.

Abstract translation: 本发明的实施例涉及包括运动传感器和用于测量心脏性能的相关方法的可植入装置。 在一个实施例中，本发明包括可植入电刺激引线。 电刺激引线可以包括具有近端和远端的引线主体和限定中心内腔的护套。 引线体还可以包括设置在护套的中心腔内的电导体。 刺激引线还可以包括位于引线体的远端处的刺激电极，该刺激电极与电导体电连通。 电刺激引线可以包括耦合到引线主体的屈曲传感器，所述运动传感器被配置为响应于引线主体的移动而产生信号。 在一个实施例中，本发明包括监测心力衰竭患者状况的方法。 在一个实施方案中，本发明包括治疗患者不稳定性心律失常的方法。 本文还包括其它实施例。

公开(公告)号：US20110218594A1

公开(公告)日：2011-09-08

申请号：US13038754

申请日：2011-03-02

Applicant: Eyal Doron ,  Bin Mi ,  Abhi V. Chavan ,  Keith R. Maile

Inventor： Eyal Doron ,  Bin Mi ,  Abhi V. Chavan ,  Keith R. Maile

IPC: A61N1/08 ,  G10K9/122

CPC classification number: G10K9/122 ,  A61B2560/0214 ,  A61N1/37217 ,  G08C23/02 ,  H04B11/00

Abstract: A piezoelectric element within an external ultrasonic transducer assembly can be used for wireless communication of data between an implantable device and the external ultrasonic transducer assembly such as using ultrasonic energy coupled to a flexible portion of a housing of the transducer assembly. The flexible portion can be configured to contact skin of a body containing the implantable device. The transducer assembly can be configured to respectively transmit or receive ultrasonic energy using at least partially overlapping respective ranges of resonant frequencies.

Abstract translation: 外部超声波换能器组件内的压电元件可用于可植入装置与外部超声换能器组件之间的数据的无线通信，例如使用耦合到换能器组件的壳体的柔性部分的超声波能量。 柔性部分可以构造成接触包含可植入装置的身体的皮肤。 换能器组件可以被配置为使用至少部分重叠的各个谐振频率范围分别发送或接收超声波能量。

公开(公告)号：US20100317977A1

公开(公告)日：2010-12-16

申请号：US12774976

申请日：2010-05-06

Applicant: Thomas W. Piaget ,  Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Cheng Zhang

Inventor： Thomas W. Piaget ,  Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Cheng Zhang

IPC: A61B5/0215 ,  H02N2/18

CPC classification number: H01L41/1138 ,  A61B5/0031 ,  A61B5/0215 ,  H02N2/18

Abstract: Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative power generation module disposable within the interior space of an implantable medical device includes a module body that defines an interior cavity as well as a flexible diaphragm that spans the interior cavity. The flexible diaphragm includes a first electrical conductor, a piezoelectric layer disposed adjacent to the first electrical conductor, and a second electrical conductor disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace within the interior cavity and generate a voltage differential between the first electrical conductor and the second electrical conductor.

Abstract translation: 描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。 在可植入医疗装置的内部空间内可放置的说明性发电模块包括限定内腔的模块主体以及跨越内腔的柔性隔膜。 柔性隔膜包括第一电导体，邻近第一电导体设置的压电层和邻近压电层设置的第二电导体。 压电层被配置为在内腔内移位，并在第一电导体和第二电导体之间产生电压差。

公开(公告)号：US09750416B2

公开(公告)日：2017-09-05

申请号：US13438682

申请日：2012-04-03

Applicant: Wangcai Liao ,  Jeffrey Stahmann ,  Bin Mi ,  Yunlong Zhang

Inventor： Wangcai Liao ,  Jeffrey Stahmann ,  Bin Mi ,  Yunlong Zhang

IPC: A61B5/02 ,  A61B5/0215 ,  A61B5/08 ,  A61B5/00 ,  A61B5/021

CPC classification number: A61B5/0215 ,  A61B5/02007 ,  A61B5/02108 ,  A61B5/08 ,  A61B5/412 ,  A61B5/6846 ,  A61B5/7275

Abstract: Systems and methods provide for ambulatorily sensing pulmonary artery pressure from within a patient, and producing a pulmonary artery pressure measurement from the sensed pulmonary artery pressure. Power is ambulatorily provided within the patient to facilitate sensing of the pulmonary artery pressure and producing of the pulmonary artery pressure measurement. Acute pulmonary embolism is detected based on a change or rate of change in the pulmonary artery pressure measurement. An alert is preferably generated in response to detecting pulmonary embolism.

公开(公告)号：US08825161B1

公开(公告)日：2014-09-02

申请号：US12122431

申请日：2008-05-16

Applicant: Bin Mi ,  Lawrence D. Swanson ,  Mark S. Bartrum

Inventor： Bin Mi ,  Lawrence D. Swanson ,  Mark S. Bartrum

IPC: A61N1/08

CPC classification number: A61N1/3684 ,  A61N1/0563 ,  A61N1/36578 ,  A61N1/37217

Abstract: An implantable medical device includes a housing defining a hermetically sealed chamber and includes a diaphragm portion having a first resonance frequency, an acoustic communication circuit within the chamber, and an acoustic transducer within the chamber. The transducer includes a substantially rigid pin member attached to an inner surface of the diaphragm portion, and an active portion coupled to the pin member. The active portion has a second resonant frequency and includes a piezoelectric element electrically coupled to the acoustic communication circuit. The diaphragm portion and the active transducer portion may be configured such that the first and second resonance frequencies are substantially equal.

Abstract translation: 可植入医疗装置包括限定密封室的壳体，并且包括具有第一共振频率的膜部分，腔室内的声学通信电路以及腔室内的声换能器。 换能器包括附接到隔膜部分的内表面的基本刚性的销构件以及联接到销构件的有效部分。 有源部分具有第二谐振频率，并且包括电耦合到声通信电路的压电元件。 隔膜部分和有源换能器部分可以被配置成使得第一和第二谐振频率基本相等。

公开(公告)号：US08777863B2

公开(公告)日：2014-07-15

申请号：US12774976

申请日：2010-05-06

Applicant: Thomas W. Piaget ,  Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Cheng Zhang

Inventor： Thomas W. Piaget ,  Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Cheng Zhang

IPC: A61B5/02

CPC classification number: H01L41/1138 ,  A61B5/0031 ,  A61B5/0215 ,  H02N2/18

Abstract: Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative power generation module disposable within the interior space of an implantable medical device includes a module body that defines an interior cavity as well as a flexible diaphragm that spans the interior cavity. The flexible diaphragm includes a first electrical conductor, a piezoelectric layer disposed adjacent to the first electrical conductor, and a second electrical conductor disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace within the interior cavity and generate a voltage differential between the first electrical conductor and the second electrical conductor.

Abstract translation: 描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。 在可植入医疗装置的内部空间内可放置的说明性发电模块包括限定内腔的模块主体以及跨越内腔的柔性隔膜。 柔性隔膜包括第一电导体，邻近第一电导体设置的压电层和邻近压电层设置的第二电导体。 压电层被配置为在内腔内移位，并在第一电导体和第二电导体之间产生电压差。

公开(公告)号：US08506495B2

公开(公告)日：2013-08-13

申请号：US12774983

申请日：2010-05-06

Applicant: Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget

Inventor： Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget

IPC: A61B5/02

CPC classification number: A61N1/36564 ,  A61B5/0031 ,  A61B5/0215 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/375

Abstract: Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative implantable medical device includes a housing having an internal cavity and a flexible anchor assembly that is coupled to the housing. The flexible anchor assembly includes a first electrical conductor, a second electrical conductor, and a piezoelectric layer that is disposed between the first and second electrical conductors and that is configured to displace in response to a physiologic force applied to the flexible anchor assembly and generate a voltage differential between the first and second electrical conductors. The implantable medical device includes power circuitry that converts the voltage differential between the first and second electrical conductors into an operating current for powering one or more components within the implantable medical device and/or for recharging a rechargeable power supply within the device.

Abstract translation: 描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。 示例性可植入医疗装置包括具有内腔的壳体和联接到壳体的柔性锚固组件。 柔性锚固组件包括第一电导体，第二电导体和压电层，其被设置在第一和第二电导体之间，并被配置为响应于施加到柔性锚固组件的生理力而移位并产生 第一和第二电导体之间的电压差。 可植入医疗装置包括电力电路，其将第一和第二电导体之间的电压差转换成用于为可植入医疗装置内的一个或多个部件供电的动作电流和/或用于为装置内的可再充电电源再充电。

公开(公告)号：US08204599B2

公开(公告)日：2012-06-19

申请号：US12103963

申请日：2008-04-16

Applicant: Wangcai Liao ,  Bin Mi ,  Rodney W. Salo

Inventor： Wangcai Liao ,  Bin Mi ,  Rodney W. Salo

IPC: A61N1/00

CPC classification number: A61B5/02152 ,  A61B5/6862 ,  A61B5/6876 ,  A61B5/6882

Abstract: A system and a method of disposing a second sensor module overlying a first sensor module system is described. A first assembly including an expandable anchor and a sensor module is at least partially overlapped by a second assembly including an expandable anchor and a sensor module. If necessary or desired, the functions of the second sensor module can replace the functions of the first sensor module. The sensor module may include a blood pressure sensor.

Abstract translation: 描述了布置覆盖在第一传感器模块系统上的第二传感器模块的系统和方法。 包括可扩张锚和传感器模块的第一组件至少部分地由包括可扩张锚和传感器模块的第二组件重叠。 如果需要或需要，第二传感器模块的功能可以替代第一传感器模块的功能。 传感器模块可以包括血压传感器。

公开(公告)号：US07949396B2

公开(公告)日：2011-05-24

申请号：US11780992

申请日：2007-07-20

Applicant: Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

Inventor： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

IPC: A61N1/375

CPC classification number: A61N1/37288 ,  A61B5/0028 ,  A61N1/37217

Abstract: An implantable medical device comprising a housing and an ultrasonic transducer having a communication frequency coupled to a portion of the housing. The housing resonates at the communication frequency, and a casing is coupled to the housing and disposed over the ultrasonic transducer. The casing is adapted to amplify the deformation of the ultrasonic transducer in a bending mode and transfer the bending moment to the housing. An implantable medical device comprising a housing having an upper portion and a lower portion. A first ultrasonic transducer is coupled to a first connection rod and is coaxial with the first connection rod. The first ultrasonic transducer and first connection rod are interposed between the upper and lower portions such that the first ultrasonic transducer is adapted to vibrate the upper and lower portions simultaneously. A method of optimizing an ultrasonic transducer and a housing of an implantable medical device.

Abstract translation: 一种可植入医疗装置，包括壳体和具有耦合到壳体的一部分的通信频率的超声换能器。 壳体以通信频率谐振，并且壳体耦合到壳体并且设置在超声换能器上。 壳体适于在弯曲模式下放大超声波换能器的变形，并将弯矩转移到壳体。 一种可植入医疗装置，包括具有上部和下部的壳体。 第一超声换能器联接到第一连接杆并且与第一连接杆同轴。 第一超声波换能器和第一连接杆插入在上部和下部之间，使得第一超声波换能器适于同时振动上部和下部。 一种优化超声换能器和可植入医疗装置的壳体的方法。

公开(公告)号：US20100317929A1

公开(公告)日：2010-12-16

申请号：US12774983

申请日：2010-05-06

Applicant: Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget

Inventor： Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget

IPC: A61B5/00 ,  A61N1/365

CPC classification number: A61N1/36564 ,  A61B5/0031 ,  A61B5/0215 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/375

Abstract: Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative implantable medical device includes a housing having an internal cavity and a flexible anchor assembly that is coupled to the housing. The flexible anchor assembly includes a first electrical conductor, a second electrical conductor, and a piezoelectric layer that is disposed between the first and second electrical conductors and that is configured to displace in response to a physiologic force applied to the flexible anchor assembly and generate a voltage differential between the first and second electrical conductors. The implantable medical device includes power circuitry that converts the voltage differential between the first and second electrical conductors into an operating current for powering one or more components within the implantable medical device and/or for recharging a rechargeable power supply within the device.

Abstract translation: 描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。 示例性可植入医疗装置包括具有内腔的壳体和联接到壳体的柔性锚固组件。 柔性锚固组件包括第一电导体，第二电导体和压电层，其被设置在第一和第二电导体之间，并被配置为响应于施加到柔性锚固组件的生理力而移位并产生 第一和第二电导体之间的电压差。 可植入医疗装置包括电力电路，其将第一和第二电导体之间的电压差转换成用于为可植入医疗装置内的一个或多个部件供电的动作电流和/或用于为装置内的可再充电电源再充电。