公开(公告)号：US20240052295A1

公开(公告)日：2024-02-15

申请号：US17766625

申请日：2020-10-07

Applicant: Calysta, Inc.

Inventor： Yelena Stegantseva ,  Lisa Marie Newman ,  Warren Kwan ,  Chien-Seng Hwang ,  Lorraine Joan Giver ,  Celine Schiff-Deb

IPC: C12N1/20 ,  C07K14/195

CPC classification number: C12N1/20 ,  C07K14/195

Abstract: The present disclosure provides method for generating biomass by culturing methanotrophic bacteria under low copper conditions. Also provided are generated biomass and protein isolate prepared from the biomass.

公开(公告)号：US11480581B2

公开(公告)日：2022-10-25

申请号：US16900599

申请日：2020-06-12

Applicant: Calysta, Inc.

Inventor： Sungwon Lee ,  Allan LeBlanc

IPC: G01N33/68 ,  G01N30/72 ,  G01N29/30 ,  G01N30/86

Abstract: The present disclosure provides methods of identifying or certifying an animal that consumed a traceable diet comprising a C1 metabolizing microorganism.

公开(公告)号：US20200205440A1

公开(公告)日：2020-07-02

申请号：US16634114

申请日：2018-08-16

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Sungwon Lee

IPC: A23K10/16 ,  A23K20/158 ,  A23K50/80 ,  A23K50/75 ,  A23K10/30

Abstract: The present disclosure provides methods for improving accumulation of one or more polyunsaturated fatty acids in an animal through the use of a boosted feed composition comprising polyunsaturated fatty acids and a bacterial biomass (e.g., methylotrophic, methanotrophic, or both), wherein the animal that is fed and consumes the boosted feed composition accumulates the one or more polyunsaturated fatty acids more efficiently than when fed a reference feed composition lacking the bacterial biomass.

公开(公告)号：US20200172853A1

公开(公告)日：2020-06-04

申请号：US16774991

申请日：2020-01-28

Applicant: Calysta, Inc.

Inventor： Luan Thanh NGUYEN ,  Arild Johannessen ,  Graham Ian Aylen ,  Joshua A. Silverman

IPC: C12M1/00 ,  C12M1/42 ,  C12M1/34 ,  C12N1/30

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

公开(公告)号：US10538730B2

公开(公告)日：2020-01-21

申请号：US16405587

申请日：2019-05-07

Applicant: Calysta, Inc.

Inventor： Luan Thanh Nguyen ,  Arild Johannessen ,  Graham Ian Aylen ,  Joshua A. Silverman

IPC: C12N1/30 ,  C12M1/34 ,  C12M1/42 ,  C12M1/00

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

公开(公告)号：US20190048308A1

公开(公告)日：2019-02-14

申请号：US16102448

申请日：2018-08-13

Applicant: Calysta, Inc.

Inventor： Luan Thanh NGUYEN ,  Joshua A. Silverman ,  Graham Ian Aylen

IPC: C12M1/00 ,  C12M1/107 ,  C12M1/12

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

公开(公告)号：US10190123B2

公开(公告)日：2019-01-29

申请号：US15821510

申请日：2017-11-22

Applicant: CALYSTA, INC.

Inventor： Joshua A. Silverman ,  Effendi Leonard ,  Renee M. Saville

IPC: C12N15/52 ,  C12N1/20 ,  C12N9/00 ,  C12N9/12 ,  C12N9/04

Abstract: The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glucose) as a primary or sole carbon source and methods for growing methanotrophic bacteria on the multi-carbon substrate.

公开(公告)号：US10113188B2

公开(公告)日：2018-10-30

申请号：US15877747

申请日：2018-01-23

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman

IPC: C12P7/64 ,  C12N9/00 ,  C12P7/24 ,  C12N9/16 ,  C12P7/42 ,  C12P7/44 ,  C12N15/52 ,  C12N9/02 ,  C12N9/06 ,  C12N9/04

Abstract: The present disclosure provides compositions and methods for biologically producing fatty acid derivatives, such as fatty alcohols, from recombinant C1 metabolizing microorganisms that utilize C1 substrates such as methane or natural gas as a feedstock.

公开(公告)号：US20180251800A1

公开(公告)日：2018-09-06

申请号：US15882393

申请日：2018-01-29

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Sol M. Resnick ,  Michael Mendez ,  Renee M. Saville ,  Sungwon Lee ,  Luan Nguyen

IPC: C12P7/64 ,  C10G3/00 ,  C12N15/74 ,  C12N15/52 ,  C10G47/00 ,  C12R1/01 ,  C12N9/00 ,  C12N9/16 ,  C10L1/04 ,  C10L1/02 ,  C12N1/20 ,  C12N9/10 ,  C12N1/16 ,  C12P5/00

CPC classification number: C12P7/6409 ,  C10G3/00 ,  C10G3/50 ,  C10G47/00 ,  C10G2300/1014 ,  C10L1/02 ,  C10L1/04 ,  C10L2200/0469 ,  C10L2270/02 ,  C10L2270/04 ,  C10L2290/26 ,  C12N1/16 ,  C12N1/20 ,  C12N9/1029 ,  C12N9/16 ,  C12N9/93 ,  C12N15/52 ,  C12N15/74 ,  C12P5/00 ,  C12P7/6463 ,  C12P7/649 ,  C12R1/01 ,  C12Y203/01039 ,  C12Y301/02 ,  C12Y602/01003 ,  C12Y604/01002 ,  Y02E50/13 ,  Y02E50/343 ,  Y02P20/52 ,  Y02P30/20

Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.

公开(公告)号：US09816111B2

公开(公告)日：2017-11-14

申请号：US14429327

申请日：2013-09-18

Applicant: Calysta, Inc.

Inventor： Joshua A. Silverman ,  Thomas Joseph Purcell

IPC: C12P5/02 ,  C12N1/20

CPC classification number: C12P5/026 ,  C12N1/20 ,  C12N9/16 ,  C12N9/88 ,  Y02E50/343

Abstract: The present disclosure relates to biosynthetic methods for producing propylene and to genetically engineered organisms having propylene biosynthesis capability.