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    Rheology Control Agents
    21.
    发明申请
    Rheology Control Agents 有权
    流变控制剂

    公开(公告)号：US20100204376A1

    公开(公告)日：2010-08-12

    申请号：US12758864

    申请日：2010-04-13

    Applicant: Christian Peter Lenges ,  Yanhui Niu ,  Yu-Ling Hsiao ,  Jiang Ding ,  Robert John Barsotti ,  Renee J. Kelly ,  Robert James Butera ,  Young H. Kim

    Inventor： Christian Peter Lenges ,  Yanhui Niu ,  Yu-Ling Hsiao ,  Jiang Ding ,  Robert John Barsotti ,  Renee J. Kelly ,  Robert James Butera ,  Young H. Kim

    IPC: C09D7/12 ,  C07C271/24 ,  C07C271/22

    CPC classification number: C07C275/16 ,  C07C275/10 ,  C07C275/18 ,  C07C275/24

    Abstract: The present invention provides for a rheology control agent that includes a following compound represented by the following formula: wherein A, B, C and D equal CH2, CHR, NH, or O, and A, B, C and D may be the same or different and at least one of A and B equals NH and at least one of C and D equals NH; and wherein R1, R2, and R3 may be the same or different and represent a linear, branched, hyper-branched, or dendritic ether, polyether or hydrocarbon based chain, optionally forming at least one carbon-based ring, being saturated or unsaturated and R2 represents linear or branched alkylenes, ethers, polyethers, or polyester linkages and at least one of R1, R2, and R3 comprises an ester group or an amide group which is branched off from the main chain; excluded from Formula (1) is a compound wherein R2 is CH2—CH2—CH2—CH2—CH(C(O)OCH3), A, B, C, and D are equal to NH and R1 and R3 are both equal to a linear octyl hydrocarbon chain; the rheology control agent is suitable for solvent-borne and water-borne coating composition having improved rheology control useful for OEM refinishing or repainting the exterior of automobile and truck bodies and parts thereof.

    Abstract translation: 本发明提供一种流变控制剂，其包含由下式表示的以下化合物：其中A，B，C和D等于CH 2，CHR，NH或O，A，B，C和D可以相同 或不同且A和B中的至少一个等于NH，C和D中的至少一个等于NH; 并且其中R 1，R 2和R 3可以相同或不同，表示直链，支链，超支化或树枝状醚，聚醚或烃基链，任选地形成至少一个饱和或不饱和的碳基环， R2表示直链或支链亚烷基，醚，聚醚或聚酯键，R 1，R 2和R 3中的至少一个包含从主链分支的酯基或酰胺基; 从式（1）中排除的是其中R 2是CH 2 -CH 2 -CH 2 -CH 2 -CH（C（O）OCH 3），A，B，C和D等于NH并且R 1和R 3均等于 直链辛基烃链; 流变控制剂适用于具有改进的流变控制的溶剂型和水性涂料组合物，其可用于OEM修补或重新涂刷汽车和卡车车身及其部件的外部。

    Selective resynchronization therapy optimization based on user preference
    23.
    发明授权
    Selective resynchronization therapy optimization based on user preference 失效
    基于用户偏好的选择性再同步治疗优化

    公开(公告)号：US07613514B2

    公开(公告)日：2009-11-03

    申请号：US11109603

    申请日：2005-04-19

    Applicant: Richard Fogoros ,  Jiang Ding ,  Yinghong Yu

    Inventor： Richard Fogoros ,  Jiang Ding ,  Yinghong Yu

    IPC: A61N1/365

    CPC classification number: A61N1/3627 ,  A61N1/36564 ,  A61N1/3682 ,  A61N1/3684

    Abstract: A method and system for calculating an atrio-ventricular delay interval based upon an inter-atrial delay exhibited by a patient's heart. The aforementioned atrio-ventricular delay interval may optimize the stroke volume exhibited by a patient's heart. The aforementioned atrio-ventricular delay interval may be blended with another atrio-ventricular delay interval that may optimize another performance characteristic, such as left ventricular contractility. Such blending may include finding an arithmetic mean, geometric mean, or weighted mean of two or more proposed atrio-ventricular delay intervals.

    Abstract translation: 一种用于根据患者心脏表现的心房间延迟来计算心房延迟间隔的方法和系统。 上述的心室延迟间隔可以优化患者心脏展示的搏动量。 上述房室延迟间隔可以与可以优化另一性能特征（例如左心室收缩力）的另一心房延迟间隔混合。 这种混合可以包括找到两个或更多个提出的心房延迟间隔的算术平均值，几何平均值或加权平均值。

    Automatic Capture Verification using Electrocardiograms Sensed from Multiple Implanted Electrodes
    24.
    发明申请
    Automatic Capture Verification using Electrocardiograms Sensed from Multiple Implanted Electrodes 失效
    使用从多个植入电极感测的心电图进行自动捕获验证

    公开(公告)号：US20090198301A1

    公开(公告)日：2009-08-06

    申请号：US12409348

    申请日：2009-03-23

    Applicant: Yi Zhang ,  Jiang Ding ,  Aaron R. McCabe ,  Scott A. Meyer

    Inventor： Yi Zhang ,  Jiang Ding ,  Aaron R. McCabe ,  Scott A. Meyer

    IPC: A61N1/37

    CPC classification number: A61N1/3712 ,  A61N1/365

    Abstract: Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed for automatic capture verification using cardiac activation sequence information. Devices and methods sense composite cardiac signals using implantable electrodes. A source separation is performed using the composite signals. One or more signal vectors are produced that are associated with all or a portion of one or more cardiac activation sequences based on the source separation. A cardiac response to the pacing pulses is classified using characteristics associated with cardiac signal vectors and the signals associated with the vectors. Further embodiments may involve classifying the cardiac response as capture or non-capture, fusion or intrinsic cardiac activity. The characteristics may include an angle or an angle change of the cardiac signal vectors, such as a predetermined range of angles of the one or more cardiac signal vectors.

    Abstract translation: 提供一种或多种监测，诊断，除颤和起搏的心脏监测和/或刺激方法和系统。 心脏信号分离被用于使用心脏激活序列信息的自动捕获验证。 装置和方法使用可植入电极感测复合心脏信号。 使用复合信号进行源分离。 产生与基于源分离的一个或多个心脏激活序列的全部或一部分相关联的一个或多个信号载体。 使用与心脏信号矢量相关联的特征和与矢量相关联的信号来分类对起搏脉冲的心脏反应。 进一步的实施方案可以包括将心脏反应分类为捕获或非捕获，融合或内在心脏活动。 特征可以包括心脏信号矢量的角度或角度变化，例如一个或多个心脏信号矢量的预定角度范围。

    AV DELAY FEATURES
    25.
    发明申请
    AV DELAY FEATURES 有权
    AV延迟功能

    公开(公告)号：US20090163970A1

    公开(公告)日：2009-06-25

    申请号：US12336064

    申请日：2008-12-16

    Applicant: Yinghong Yu ,  Jiang Ding

    Inventor： Yinghong Yu ,  Jiang Ding

    IPC: A61N1/362

    CPC classification number: A61N1/368 ,  A61B5/0452 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3684

    Abstract: At least one of a left intraventricular conduction defect, a right intraventricular conduction defect, or no intraventricular conduction defect can be detected using received intrinsic cardiac information from a subject, and a first atrioventricular (AV) delay can be calculated using a first relationship if the left intraventricular conduction defect or no intraventricular conduction defect is detected, or a second AV delay can be calculated using a second relationship if the right intraventricular conduction defect is detected.

    Abstract translation: 可以使用来自受试者的接收的固有心脏信息来检测左室内传导缺陷，右心室内传导缺陷或无心室内传导缺陷中的至少一个，并且可以使用第一关系来计算第一房室（AV）延迟，如果 如果检测到右心室传导缺陷，则检测到左心室内传导缺陷或无心室传导缺陷，或者可以使用第二关系计算第二AV延迟。

    CARDIAC STIMULATION DEVICE FOR SINUS RATE MODULATION
    27.
    发明申请
    CARDIAC STIMULATION DEVICE FOR SINUS RATE MODULATION 有权
    用于SINUS速率调制的心脏刺激装置

    公开(公告)号：US20080147138A1

    公开(公告)日：2008-06-19

    申请号：US11610821

    申请日：2006-12-14

    Applicant: Barun Maskara ,  Jiang Ding ,  Imad Libbus

    Inventor： Barun Maskara ,  Jiang Ding ,  Imad Libbus

    IPC: A61N1/05

    CPC classification number: A61N1/0587 ,  A61N1/36514 ,  A61N1/3956

    Abstract: A system comprising an implantable electrical cardiac signal sensing circuit, an implantable sinoatrial cardiac action potential detector circuit, and an implantable electrical stimulation circuit in electrical communication with the electrical cardiac signal sensing circuit and the sinoatrial cardiac action potential detector circuit. The electrical cardiac signal sensing circuit is configured to receive one or more intrinsic heart signals from one or more respective electrodes configured for placement in a vicinity of a sinoatrial node of a subject. The implantable electrical stimulation circuit is configured to initiate delivery of at least one inhibitory electrical stimulation pulse in a vicinity of the sinoatrial node in a timed relationship to a sensed sinoatrial cardiac action potential. Other systems and methods are disclosed.

    Abstract translation: 一种包括可植入电气心脏信号感测电路，可植入窦房心脏动作电位检测器电路和与电心脏信号感测电路和窦房心脏动作电位检测器电路电通信的可植入电刺激电路的系统。 电心脏信号感测电路被配置为从被配置为放置在受试者的窦房结附近的一个或多个相应电极接收一个或多个固有心脏信号。 可植入电刺激电路被配置为以与所感测的窦房心脏动作电位的定时关系开始在窦房结附近发送至少一个抑制性电刺激脉冲。 公开了其它系统和方法。

    Ventricular conduction delay trending system and method
    28.
    发明授权
    Ventricular conduction delay trending system and method 有权
    心室传导延迟趋势系统及方法

    公开(公告)号：US07383086B2

    公开(公告)日：2008-06-03

    申请号：US10889354

    申请日：2004-07-12

    Applicant: Jiang Ding

    Inventor： Jiang Ding

    IPC: A61N1/368

    CPC classification number: A61N1/3702 ,  A61N1/3627 ,  A61N1/365

    Abstract: A method and system for ascertaining the condition of the heart's conduction system in a patient treated for congestive heart failure with pacing therapy. In accordance with the invention, changes in ventricular activation patterns are monitored over time in order to detect changes in the heart's conduction system that may occur due to physiological regeneration of conduction pathways. The activation patterns are reflected by electrogram signals detected from different ventricular locations. By measuring the difference in conduction times of an excitation impulse traveling from the AV node to the different ventricular locations, a parameter representative of the heart's conduction system is obtained that may be used to adjust the pacing therapy in accordance therewith.

    Abstract translation: 一种确定心脏传导系统状态的方法和系统，用于采用起搏治疗充血性心力衰竭治疗的患者。 根据本发明，随着时间的推移监测心室激活模式的变化，以便检测由于传导途径的生理再生而可能发生的心脏传导系统的变化。 激活模式由从不同心室位置检测到的电描记图信号反映。 通过测量从AV节点行进到不同心室位置的激励脉冲的传导时间的差异，可以获得代表心脏传导系统的参数，其可用于根据其调节起搏疗法。

    Cardiac rhythm management system selecting between multiple same-chamber electrodes for delivering cardiac therapy
    29.
    发明授权
    Cardiac rhythm management system selecting between multiple same-chamber electrodes for delivering cardiac therapy 有权
    心脏节律管理系统选择多个相同室电极之间进行心脏治疗

    公开(公告)号：US07239913B2

    公开(公告)日：2007-07-03

    申请号：US10706436

    申请日：2003-11-12

    Applicant: Jiang Ding ,  Julio C. Spinelli ,  Andrew P. Kramer

    Inventor： Jiang Ding ,  Julio C. Spinelli ,  Andrew P. Kramer

    IPC: A61N1/365

    CPC classification number: A61N1/3684 ,  A61N1/3627 ,  A61N1/36514 ,  A61N1/368

    Abstract: A cardiac rhythm management system selects one of multiple electrodes associated with a particular heart chamber based on a relative timing between detection of a depolarization fiducial point at the multiple electrodes, or based on a delay between detection of a depolarization fiducial point at the multiple electrodes and detection of a reference depolarization fiducial point at another electrode associated with the same or a different heart chamber. Subsequent contraction-evoking stimulation therapy is delivered from the selected electrode.

    Abstract translation: 心脏节律管理系统基于在多个电极处的去极化基准点的检测之间的相对定时或基于在多个电极之间的去极化基准点的检测之间的延迟来选择与特定心室相关联的多个电极中的一个，以及 在与相同或不同的心室相关联的另一电极处检测参考去极化基准点。 随后的收缩诱导刺激疗法从所选择的电极递送。

    METHOD AND SYSTEM FOR SETTING CARDIAC RESYNCHRONIZATION THERAPY PARAMETERS
    30.
    发明申请
    METHOD AND SYSTEM FOR SETTING CARDIAC RESYNCHRONIZATION THERAPY PARAMETERS 有权
    用于设置心脏再生治疗参数的方法和系统

    公开(公告)号：US20070150013A1

    公开(公告)日：2007-06-28

    申请号：US11681244

    申请日：2007-03-02

    Applicant: Jiang Ding ,  Yinghong Yu ,  Bruce KenKnight

    Inventor： Jiang Ding ,  Yinghong Yu ,  Bruce KenKnight

    IPC: A61N1/362

    CPC classification number: A61N1/3627 ,  A61N1/3682 ,  A61N1/3684

    Abstract: A method or system for computing and/or setting optimal cardiac resynchronization pacing parameters as derived from intrinsic conduction data is presented. The intrinsic conduction data includes intrinsic atrio-ventricular and interventricular delay intervals which may be collected via the sensing channels of an implantable cardiac device. Among the parameters which may be optimized in this manner are an atrio-ventricular delay interval and a biventricular offset interval. In one of its aspects, the invention provides for computing optimum pacing parameters for patients having some degree of AV block or with atrial conduction deficits. Another aspect of the invention relates to a pacing mode and configuration for providing cardiac resynchronization therapy to patients with a right ventricular conduction disorder.

    Abstract translation: 提出了一种用于计算和/或设置从内在传导数据导出的最佳心脏再同步起搏参数的方法或系统。 内在传导数据包括可通过可植入心脏装置的感测通道收集的本征心室和室间延迟间隔。 可以以这种方式优化的参数是心房延迟间隔和双心室偏移间隔。 在其一个方面，本发明提供了对具有一定程度的AV阻滞或具有心房传导缺陷的患者计算最佳起搏参数。 本发明的另一方面涉及用于向患有右心室传导障碍的患者提供心脏再同步治疗的起搏模式和配置。

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