-
21.发明申请公开(公告)号：US20060057573A1
公开(公告)日：2006-03-16
申请号：US10504696
申请日：2003-02-10
Applicant: Larry Gold , Jonathan Smith , Dominic Zichi , Daniel Schneider , Chad Greef
Inventor： Larry Gold , Jonathan Smith , Dominic Zichi , Daniel Schneider , Chad Greef
CPC classification number: C12N15/115 , G01N33/58
Abstract: The present invention provides novel methods and reagents for detecting the binding of protein targets to nucleic acid ligands. Using Universal Protein Stains (UPS), proteins bound by nucleic acid ligands may be labeled with a detectable moiety. The methods and reagents are particularly useful for the detection of protein targets bound to multiplexed arrays of nucleic acid ligands. The present invention also provides novel methods for the multiplexed evaluation of photocrosslinking nucleic acid ligands. The methods allow one simultaneously to: (1) evaluate the performance (dynamic range) of a plurality of photocrosslinking nucleic acid ligands; and (2) assess the specificity of each photocrosslinking nucleic acid ligand for its cognate target protein. Photocrosslinking nucleic acid ligands with the most desirable properties can then be selected for use in diagnostic and prognostic medical assays. The present invention also provides a photocrosslinking nucleic acid ligand that binds specifically to HIV gp120MN.
Abstract translation: 本发明提供用于检测蛋白质靶标与核酸配体的结合的新型方法和试剂。 使用通用蛋白污渍（UPS），可以用可检测的部分标记由核酸配体结合的蛋白质。 所述方法和试剂对于检测与核酸配体复合阵列结合的蛋白质靶标特别有用。 本发明还提供了用于光交联核酸配体的多重评价的新方法。 该方法同时允许：（1）评估多个光交联核酸配体的性能（动态范围）; 和（2）评估每个光交联核酸配体对其同源靶蛋白的特异性。 然后可以选择具有最理想特性的光交联核酸配体用于诊断和预后医学测定。 本发明还提供了与HIV gp120MN特异性结合的光交联核酸配体。
-
公开(公告)号：US06892425B2
公开(公告)日：2005-05-17
申请号：US10358973
申请日：2003-02-05
Applicant: Jonathan Smith
Inventor： Jonathan Smith
CPC classification number: E05C21/005 , B05B13/0292 , E05D5/062 , E05D11/1014 , E05D11/1085 , E05Y2900/531 , Y10S16/17 , Y10T16/551 , Y10T16/61 , Y10T16/629
Abstract: A removable door check device for holding a vehicle door hinge in an opened position includes a body, first and second leg portions extending from the body and disposed coplanar to the body, a protrusion portion extending from the body in a direction perpendicular to the body. In addition, a door hinge that includes a first hinge part, a second hinge part, a hinge pin passing through the first and second hinge parts and a removable door check device. The first and second hinge parts are pivotable about the hinge pin between an opened and a closed position. The removable door check device of the hinge is disposed on the hinge pin exterior to the first and second hinge parts engaging the second hinge part in the opened position.
Abstract translation: 用于将车门铰链保持在打开位置的可拆卸的门检查装置包括主体，从主体延伸并且与主体共面设置的第一和第二腿部，从主体沿垂直于主体的方向延伸的突出部分。 此外，门铰链包括第一铰链部分，第二铰链部分，穿过第一和第二铰链部分的铰链销和可移除的门检查装置。 第一和第二铰链部分可在铰链销之间在打开和关闭位置之间枢转。 铰链的可拆卸的门检查装置设置在第一和第二铰链部分的外部的铰链销上，在第二铰链部分处于打开位置。
-
公开(公告)号：USD449557S1
公开(公告)日：2001-10-23
申请号：US29136274
申请日：2001-01-26
Applicant: Jonathan Smith
Designer： Jonathan Smith
-
公开(公告)号：US5987057A
公开(公告)日：1999-11-16
申请号：US635464
申请日：1996-04-22
Applicant: Gregory Jonathan Smith , Colin James Helliwell
Inventor： Gregory Jonathan Smith , Colin James Helliwell
CPC classification number: H04B1/713 , H04B1/715 , H04B1/7183 , H04J13/0022
Abstract: In wireless local area networks utilizing frequency-hopping between different channels spaced over an allotted frequency band, two or more groups of transceivers in close proximity may be arranged to operate satisfactorily with the full bandwidth available to each by arranging that their hop sequences are kept separate. This may be achieved by arranging for the hop sequence of one group or of each group to skip at intervals from one point to another in the sequence, chosen at random.
Abstract translation: 在使用在分配的频带上间隔的不同信道之间的跳频的无线局域网中，两个或更多个近距离的收发机组可以被布置成令人满意地运行，其中每个可用的全带宽通过布置它们的跳跃序列保持分开 。 这可以通过布置一组或每组的跳序来以随机选择的序列中的一个点到另一个的间隔跳过来实现。
-
公开(公告)号：US09358419B1
公开(公告)日：2016-06-07
申请号：US14208731
申请日：2014-03-13
Applicant: Jonathan Smith
Inventor： Jonathan Smith
CPC classification number: A63B21/06 , A63B21/00181 , A63B21/0552 , A63B21/0557 , A63B21/068 , A63B21/072 , A63B21/0724 , A63B21/075 , A63B21/4035 , A63B21/4049 , A63B22/14 , A63B22/20 , A63B23/0233 , A63B23/03525 , A63B23/03541 , A63B23/0355 , A63B23/1209 , A63B23/1236 , A63B26/003 , A63B2023/0411
Abstract: An exercise utilizes roller ball transfers for many embodiments, and those without, as well as an ability to add and remove weights thereto from above and possibly rotate in order to perform various exercises.
Abstract translation: 许多实施例的运动使用滚珠传送，以及那些没有，以及从上方增加和移除重量的能力，并且可能旋转以进行各种练习的能力。
-
Patent Agency Ranking
公开(公告)号：US20160039326A1
公开(公告)日：2016-02-11
申请号：US14298937
申请日：2014-08-08
Applicant: Jonathan Smith , Steven Ronald Raike
Inventor： Jonathan Smith , Steven Ronald Raike
CPC classification number: B60P3/0257 , F24C15/2042 , F24C15/30
Abstract: The present invention is an indoor portable or demonstration cooking cart. Specifically it allows a cooktop and ventilation system to be integrated into the structure of a movable cooking cart and allow its use at any location with a compatible floor connection.
Abstract translation: 本发明是一种室内便携式或示范性烹饪车。 具体来说，它允许灶具和通风系统集成到可移动烹饪车的结构中，并允许其在具有兼容的地板连接的任何位置使用。
-
公开(公告)号：US20150159760A1
公开(公告)日：2015-06-11
申请号：US14566975
申请日：2014-12-11
Applicant: Christopher Glyn Booth , Richard Jonathan Smith
Inventor： Christopher Glyn Booth , Richard Jonathan Smith
CPC classification number: F16J15/3496
Abstract: A mechanical seal face component having a base material with a high ductility or tensile strength and being substantially covered with a coating for providing a sealing surface. The base material preferably includes carbon or stainless steel. The coating preferably includes hard metal alloy, for example, a tungsten-based alloy, and preferably has a thickness no greater than 1.5 mm, which may be applied by vapor deposition.
Abstract translation: 一种机械密封面部件，具有具有高延展性或拉伸强度的基材，并且基本上覆盖有用于提供密封表面的涂层。 基材优选包括碳或不锈钢。 涂层优选包括硬质合金，例如钨基合金，并且优选具有不大于1.5mm的厚度，其可以通过气相沉积施加。
-
公开(公告)号：US20140323936A1
公开(公告)日：2014-10-30
申请号：US14325935
申请日：2014-07-08
Applicant: Jonathan SMITH , Kern Bhugra
Inventor： Jonathan SMITH , Kern Bhugra
IPC: A61F5/01
CPC classification number: A61F5/0125 , A61F5/0102
Abstract: A multi-fit orthotic structure including an attachment system for coupling the orthotic structure to a wide variety of subjects without requiring a custom fit. In one embodiment, active mobility assistance is provided via an orthotic system capable of integrating a linear actuator and linkage system to deliver torque to the lower leg of a subject to facilitate flexion and/or extension motion of the subject's leg. The orthotic structure is attached to the subject using a textile suspension system which does not require the orthotic structure to interface directly in the knee region or at the lateral areas of the thigh and calf of the subject, thus providing an ideal fit for the widest possible range of subjects with the minimum number of required sizes.
Abstract translation: 一种多合适矫形器结构，包括用于将矫形器结构与各种各样的受试者联接而不需要定制配合的附接系统。 在一个实施例中，通过能够集成线性致动器和联动系统的矫正系统来提供主动移动辅助，以将扭矩传递到对象的小腿，以促进对象腿部的屈曲和/或伸展运动。 使用不需要矫正结构的纺织品悬挂系统将矫形器结构附接到受试者，膝关节区域或受试者的大腿和小腿的横向区域直接相接，从而为最广泛的可能性提供理想的适合 具有所需尺寸最小数量的科目范围。
-
公开(公告)号：US08771210B2
公开(公告)日：2014-07-08
申请号：US13274109
申请日：2011-10-14
Applicant: Jonathan Smith , Kern Bhugra
Inventor： Jonathan Smith , Kern Bhugra
CPC classification number: A61F5/0125 , A61F5/0102
Abstract: A multi-fit orthotic structure including an attachment system for coupling the orthotic structure to a wide variety of subjects without requiring a custom fit. In one embodiment, active mobility assistance is provided via an orthotic system capable of integrating a linear actuator and linkage system to deliver torque to the lower leg of a subject to facilitate flexion and/or extension motion of the subject's leg. The orthotic structure is attached to the subject using a textile suspension system which does not require the orthotic structure to interface directly in the knee region or at the lateral areas of the thigh and calf of the subject, thus providing an ideal fit for the widest possible range of subjects with the minimum number of required sizes.
Abstract translation: 一种多合适矫形器结构，包括用于将矫形器结构与各种各样的受试者联接而不需要定制配合的附接系统。 在一个实施例中，通过能够集成线性致动器和联动系统的矫正系统来提供主动移动辅助，以将扭矩传递到对象的小腿，以促进对象腿部的屈曲和/或伸展运动。 使用不需要矫正结构的纺织品悬挂系统将矫形器结构附接到受试者，膝关节区域或受试者的大腿和小腿的侧向区域直接接合，从而为最广泛的可能性提供理想的适合 具有所需尺寸最小数量的科目范围。
-
公开(公告)号：US20140131120A1
公开(公告)日：2014-05-15
申请号：US14162553
申请日：2014-01-23
Applicant: Robert W. HORST , Robert L. JARDINE , Jonathan SMITH , Edith ARNOLD
Inventor： Robert W. HORST , Robert L. JARDINE , Jonathan SMITH , Edith ARNOLD
CPC classification number: A61B5/1036 , A61B5/1038 , G01G19/44 , G01G23/3735
Abstract: A foot pad device includes a foot pad, force sensors that provide force data, sensor electronics coupled to the force sensors, and a processor. The foot pad includes a ball region configured to be located under a ball of the foot of the user or a heel region configured to be located under a heel of the foot of the user. At least a portion of the force sensors is located in the ball region or the heel region of the foot pad. The sensor electronics include a flexible circuit with force sensor connection paths adapted to transmit force data from the force sensors and are configured to condition the force data to be within a conditioned force data range. The processor is configured to calculate a weight value based on the conditioned force data, a gain value, and an offset value.
Abstract translation: 足垫装置包括脚垫，提供力数据的力传感器，耦合到力传感器的传感器电子装置和处理器。 足垫包括被配置为位于使用者的脚的球下方的球区域或被配置为位于使用者的脚的后跟下方的跟部区域。 力传感器的至少一部分位于脚垫的球区域或跟部区域中。 传感器电子器件包括柔性电路，其具有适于从力传感器传递力数据的力传感器连接路径，并且被配置为将力数据调节在调节的力数据范围内。 处理器被配置为基于条件的力数据，增益值和偏移值来计算权重值。
-
-
-
-
-
-
-
-
-
Search Results
140
records
(took 0.015 seconds)
