公开(公告)号：US20170087198A1

公开(公告)日：2017-03-30

申请号：US15126870

申请日：2015-03-19

Applicant: Stellenbosch University

Inventor： Barbara Huisamen ,  Cindy George

IPC: A61K36/48

CPC classification number: A61K36/48

Abstract: The use of plant material from the Prosopis glandulosa tree (commonly known as Honey mesquite) is described for aiding sporting ability, and in particular for preventing and/or treating muscle injury and enhancing muscle strength. The plant material is typically the dried and ground pods from the tree, but could also be from other parts of the tree, such as the leaves, bark or roots.

公开(公告)号：US20150230885A1

公开(公告)日：2015-08-20

申请号：US14378871

申请日：2013-02-01

Applicant: STELLENBOSCH UNIVERSITY

Inventor： Tim Wucher

IPC: A61C7/00

CPC classification number: A61C7/008 ,  A61C7/00 ,  A61C7/002

Abstract: A medical apparatus for use in the corrective treatment of malocclusion and other dentofacial defects is provided. The apparatus has at least one stimulator which is configured to apply a stimulus to a part of the dento-oral complex and includes at least one actuator controllable by means of electronic signals. A feedback system is also provided and is configured to measure parameters relating to the biomechanical tissue response resulting from the stimulus applied by the at least one stimulator, to analyse the parameters by means of a processor, and to adjust the stimulus applied by the at least one stimulator by means of the required control signals in order to apply a stimulus representing an optimal orthodontic force.

Abstract translation: 提供了一种用于矫正牙齿咬合和其他牙缺陷的矫正治疗的医疗设备。 所述装置具有至少一个刺激器，其被配置为对所述牙科口腔复合体的一部分施加刺激，并且包括至少一个可通过电子信号控制的致动器。 还提供反馈系统，并且被配置为测量与由至少一个刺激器施加的刺激产生的生物力学组织响应相关的参数，以通过处理器分析参数，并且调整由至少应用的刺激 一个刺激器通过所需的控制信号，以便应用表示最佳正畸力的刺激。

公开(公告)号：US12241887B2

公开(公告)日：2025-03-04

申请号：US18571901

申请日：2022-06-23

Applicant: STELLENBOSCH UNIVERSITY

Inventor： Gideon Wolfaardt ,  Kyle Brent Klopper

IPC: G01N33/497 ,  G01N21/59 ,  G01N21/85 ,  G01N21/94

Abstract: An apparatus and system for measuring and monitoring fouling parameters in a fluid are provided. The apparatus includes a conduit within a housing, wherein at least a portion of the conduit provides a carbon dioxide permeable membrane through which carbon dioxide in the fluid can permeate in use. A carbon dioxide sensor within the housing is configured to measure carbon dioxide levels at the sensor. The housing further includes a light source that irradiates a portion of the conduit and a light sensor that is configured to measure light transmitted through or reflected by the irradiated portion of the conduit to measure the amount of fouling material within the fluid and attached to the irradiated portion of the conduit in use.

公开(公告)号：US11852629B2

公开(公告)日：2023-12-26

申请号：US17254489

申请日：2019-07-01

Applicant: Stellenbosch University

Inventor： Benjamin Loos ,  Jan Hendrik Servaas Hofmeyr ,  Willem Jacobus Perold ,  Andre Du Toit

IPC: G01N33/543 ,  G01N33/68

CPC classification number: G01N33/5438 ,  G01N33/6845

Abstract: A method, device and system for determining autophagic flux are claimed. The levels of proteins which change with increased or decreased autophagy are determined in a sample. The change in the level of each protein is quantified in order to obtain the autophagic flux. This can be compared to a sample flux range associated with autophagy dysfunction or ageing patterns. Diseases or conditions which may be diagnosed include neurodegenerative conditions such as Alzheimer's disease and dementia, cancer, heart conditions, immune conditions or aging-related conditions. The device for determining autophagic flux comprises a housing, receiving zones configured for receiving a substrate and a biological sample, and a set of electrodes for each receiving zone. The device is connectable to circuitry that determines an electrical property of each substrate and uses this to determine the autophagic flux.

公开(公告)号：US20230341151A1

公开(公告)日：2023-10-26

申请号：US18028888

申请日：2021-10-01

Applicant: Stellenbosch University

Inventor： Willem Jacobus Smit

IPC: F24S50/20 ,  G06T7/60 ,  G06T7/73 ,  G06T7/13

CPC classification number: F24S50/20 ,  G06T7/60 ,  G06T7/73 ,  G06T7/13 ,  G06T2207/10024 ,  G06T2207/10032 ,  F24S2050/25 ,  F24S23/77

Abstract: Systems and methods for calibrating a heliostat (104) are disclosed. An imaging device (100) is positioned and oriented so that a calibration target (130) reflected by the heliostat (103) is visible at the imaging device and an image taken. Multiple features of the reflected calibration target in the image are identified and used to determine a centroid of reflection within the image which is then mapped to a corresponding centroid position on the calibration target. A vector t that extends between the centroid position on the calibration target and a known position of the heliostat, as well as a vectors that extends between the known positions of the imaging device and of the heliostat, are determined. A normal vector nof the heliostat is determined as the vector that bisects s and t and is used to calibrate the heliostat by updating parameters of a heliostat tracking model.

公开(公告)号：US20230293260A1

公开(公告)日：2023-09-21

申请号：US18008121

申请日：2021-06-01

Applicant: STELLENBOSCH UNIVERSITY

Inventor： Edward Joseph FUZY

IPC: A61B90/40 ,  A61G10/00

CPC classification number: A61B90/40 ,  A61G10/005 ,  A61B2090/401

Abstract: A containment device includes a substantially transparent structure having a top, an open bottom with bottom edges aligned in a plane to form a planar base, and a plurality of sidewalls extending from the bottom to the top that define an interior for a patient’s head. A first sidewall has a pair of access openings for an operator’s hands, and an open end opposite the first sidewall is sized to accommodate at least a portion of the patient’s upper body when in use. The top includes a fist transparent panel extending from the first sidewall towards the open end at an upward incline relative to the plane (AA) of the base, the first transparent panel providing the operator with an undistorted and unobstructed view of the patient’s head.

公开(公告)号：US20220227694A1

公开(公告)日：2022-07-21

申请号：US17605769

申请日：2020-04-23

Applicant: Stellenbosch University

Inventor： Ndumiso SIBANDA ,  Harold PASCH ,  Helen PFUKWA

IPC: C07C45/67

Abstract: The invention provides a method for depolymerising a phenolic polymer, the method comprising reacting the phenolic polymer with dimethylsulphoxide (DMSO) and a hydrogen halide. The phenolic polymer may be selected from the group consisting of lignin and derivatives thereof. The hydrogen halide may be HBr. The quantity of hydrogen halide per gram of phenolic polymer may be from 30 mmoles to 70 mmoles. The quantity of DMSO per gram of phenolic polymer may be from 0.1 mole to 1 mole. The reaction may be performed at a temperature of from 100 to 120° C. The reaction may be carried out for between 10 h and 14 h. The product of the reaction may comprise vanillin.

公开(公告)号：US20220183508A1

公开(公告)日：2022-06-16

申请号：US17549304

申请日：2021-12-13

Applicant: STELLENBOSCH UNIVERSITY

Inventor： Kimberly Ann Kasper

IPC: A47J47/01 ,  B65D83/06

Abstract: A dispenser, a dispensing system and a dispensing method are disclosed. A plurality of dispensers may be implemented. The dispenser includes a flexible container having a top and a bottom and capable of holding a product therein, the flexible container including top and bottom openings. A rigid support structure that supports the flexible container is provided. A moveable dispensing arm that operatively facilitates product dispensing is also provided. The moveable dispensing arm is operable between a dispensing condition and a retaining condition, and it includes a pinching edge which is configured to pinch the flexible container shut in either the dispensing condition or the retaining condition of the dispensing arm.

公开(公告)号：US20210199668A1

公开(公告)日：2021-07-01

申请号：US17057628

申请日：2019-05-23

Applicant: STELLENBOSCH UNIVERSITY

Inventor： Novel Njweipi Chegou ,  Regan Shane Solomons ,  Gerhard Walzl ,  Masilo Charles Manyelo

IPC: G01N33/68

Abstract: Methods, devices, kits and computer-implemented methods for diagnosing (and optionally treating) tuberculous meningitis (TBM) are provided. In one embodiment, the method comprises testing a cerebrospinal fluid (CSF) sample from a subject suspected of having TBM for the presence of MPO and at least two other biomarkers, at least one of the other biomarkers being selected from the group consisting of IFN-γ, sICAM-1, VEGF-A and CXCL8. For example, the method can comprise testing the sample for MPO, IFN-γ and VEGF-A or for MPO, IFN-γ, sICAM-1 and CXCL8. In another embodiment, the method comprises testing a blood sample from a subject suspected of having TBM for the presence of at least one biomarker selected from the group consisting of adipsin (complement factor D), Ab42 and IL-10, and at least two other biomarkers. In one example, the method comprises testing the sample for the presence of adipsin (complement factor D), Ab42 and EL-10.

公开(公告)号：US20210187068A1

公开(公告)日：2021-06-24

申请号：US16640039

申请日：2017-10-04

Applicant: Stellenbosch University ,  The University of Manchester

Inventor： Etheresia Pretorius ,  Douglas Bruce Kell

IPC: A61K38/17 ,  A61P25/28

Abstract: A method for treating a subject suffering from Alzheimer's disease is provided. The method includes administering to the subject a therapeutically effective amount of lipopolysaccharide-binding protein (LBP). A composition including a therapeutically effective amount of LBP is also provided.