公开(公告)号：US09693713B2

公开(公告)日：2017-07-04

申请号：US15193499

申请日：2016-06-27

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Louis Pace ,  Peter G. Robinson ,  Udo Hoss ,  Samuel Mason Curry ,  Phillip William Carter ,  Vincent Michael DiPalma ,  Amit Mhatre ,  Jennifer Olson ,  Manuel Luis Miguel Donnay ,  Marc Barry Taub

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/15 ,  A61B5/151 ,  A61B5/157 ,  A61B50/30

CPC classification number: A61B5/14503 ,  A61B5/0004 ,  A61B5/1411 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150305 ,  A61B5/150335 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150748 ,  A61B5/15087 ,  A61B5/150877 ,  A61B5/15105 ,  A61B5/15144 ,  A61B5/157 ,  A61B5/6849 ,  A61B50/3001 ,  A61B2560/0443 ,  A61B2560/063 ,  A61B2562/242

Abstract: Devices associated with on-body analyte sensor units are disclosed. These devices include any of packaging and/or loading systems, applicators and elements of the on-body sensor units themselves. Also, various approaches to connecting electrochemical analyte sensors to and/or within associated on-body analyte sensor units are disclosed. The connector approaches variously involve the use of unique sensor and ancillary element arrangements to facilitate assembly of separate electronics assemblies and sensor elements that are kept apart until the end user brings them together.

公开(公告)号：US20170071513A1

公开(公告)日：2017-03-16

申请号：US15310691

申请日：2015-05-14

Applicant: Abbott Diabetes Care Inc.

Inventor： Udo Hoss ,  Erwin S. Budiman

IPC: A61B5/1495 ,  A61B5/1473 ,  A61B5/145

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B2560/0223

Abstract: Methods, computers, and systems used to improve accuracy of analyte level measurement of an in vivo positioned analyte sensor are disclosed herein. The methods, computers, and systems disclosed herein may be used to provide a calibrated analyte level. Specific embodiments relate to methods, computers, and systems for improving accuracy of glucose measurement of an in vivo positioned glucose sensor.

Abstract translation: 本文公开了用于提高体内定位的分析物传感器的分析物水平测量的准确度的方法，计算机和系统。 本文公开的方法，计算机和系统可用于提供校准的分析物水平。 具体实施方案涉及用于提高体内定位的葡萄糖传感器的葡萄糖测量精度的方法，计算机和系统。

公开(公告)号：US20150005601A1

公开(公告)日：2015-01-01

申请号：US14490519

申请日：2014-09-18

Applicant: Abbott Diabetes Care Inc.

Inventor： Udo Hoss ,  Christopher Allen Thomas ,  Geoffrey V. McGarraugh ,  Gary Alan Hayter

IPC: A61B5/1495 ,  A61B5/145 ,  A61B5/1473

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2560/0223 ,  A61B2562/125 ,  G01N27/3272 ,  G01N27/3274

Abstract: Methods and systems for providing continuous analyte monitoring including in vivo sensors that do not require any user calibration during in vivo use are provided. Also provided are methods and devices including continuous analyte monitoring systems that include in vivo sensors which do not require any system executed calibration or which do not require any factory based calibration, and which exhibit stable sensor sensitivity characteristics. Methods of manufacturing the no calibration sensors and post manufacturing packaging and storage techniques are also provided.

Abstract translation: 提供了用于提供连续分析物监测的方法和系统，包括在体内使用期间不需要任何用户校准的体内传感器。 还提供了包括连续分析物监测系统的方法和装置，其包括不需要任何系统执行的校准或不需要任何基于工厂的校准并且具有稳定的传感器灵敏度特性的体内传感器。 还提供了制造无校准传感器和后制造包装和存储技术的方法。

公开(公告)号：US20130345534A1

公开(公告)日：2013-12-26

申请号：US13705973

申请日：2012-12-05

Applicant: Abbott Diabetes Care Inc.

Inventor： Udo Hoss ,  Adam Heller

IPC: A61B5/1468

CPC classification number: A61B5/1468 ,  A61B5/14532 ,  G01N27/3272

Abstract: The disclosure provides method and materials for preparing biosensors (e.g., in vitro test strips and in vivo sensors) with improved mechanical properties. In some aspects, for example, the electrochemical sensors have improved durability and are better able to withstand mechanical and electrochemical stresses such as those encountered during manufacturing, transportation, storage, and use (e.g., in vivo positioning, in vivo operation, or in vitro operation). Also for example, in some aspects the electrochemical sensors are less susceptible to pinholes and other manufacturing defects that degrade performance in traditional sensors.

Abstract translation: 本公开提供了用于制备具有改进的机械性能的生物传感器（例如，体外测试条和体内传感器）的方法和材料。 在一些方面，例如，电化学传感器具有改善的耐久性，并且能够更好地承受诸如在制造，运输，储存和使用期间遇到的机械和电化学应力（例如，体内定位，体内操作或体外 操作）。 同样例如，在一些方面，电化学传感器较不易受针孔和其它制造缺陷的影响，这些缺陷降低了传统传感器的性能。

公开(公告)号：US12285251B2

公开(公告)日：2025-04-29

申请号：US17543633

申请日：2021-12-06

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Steven Scott ,  Christopher J. Bennell ,  Claire Bhogal ,  Katie A. Cranfield ,  Marc B. Taub ,  Bree M. Winter ,  Owen D. Reynolds ,  Jean-Pierre Babka ,  Dharmendra S. Patel ,  Christopher A. Thomas ,  Udo Hoss ,  Mark S. Yahnke ,  Tahir S. Khan

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/145 ,  A61M1/16

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

公开(公告)号：US20250006363A1

公开(公告)日：2025-01-02

申请号：US18886614

申请日：2024-09-16

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Daniel Milfred Bernstein ,  MIchael Love ,  Lei He ,  Christopher Allen Thomas ,  Udo Hoss ,  Benjamin Jay Feldman ,  Phillip Yee ,  Namvar Kiaie ,  Jean-Pierre Cole ,  Louis George Pace ,  Jeffery Mario Sicurello

IPC: G16H40/67 ,  A61B5/00 ,  A61B5/01 ,  A61B5/145 ,  A61B5/1486 ,  G01N33/487 ,  G16H40/63

Abstract: Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user. The in vivo analyte sensor is coupled to an electronics unit holding a memory with instruction to cause processing circuitry to initiate a predetermined time period that is longer than a predetermined life of the sensor, during the predetermined time period, convert signals from the sensor related to glucose to respective corresponding glucose levels, without relying on any post-manufacture independent analyte measurements from a reference device, and at the expiration of the predetermined time period, disable, deactivate, or cease use of one or more feature.

公开(公告)号：US12042275B2

公开(公告)日：2024-07-23

申请号：US17230149

申请日：2021-04-14

Applicant: Abbott Diabetes Care Inc.

Inventor： Udo Hoss ,  Phu Le ,  Yi Wang ,  Frank David Fujimoto ,  Suyue Qian ,  Lam Tran

IPC: A61B5/145 ,  A61B5/1473 ,  C12Q1/00

CPC classification number: A61B5/14532 ,  A61B5/1473 ,  C12Q1/001 ,  C12Q1/006

Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes an array two or more discontiguous sensing elements deposited on a substrate surface, where the sensing elements comprise one or more droplets of a sensing element formulation.

公开(公告)号：US11571147B2

公开(公告)日：2023-02-07

申请号：US16525915

申请日：2019-07-30

Applicant: Abbott Diabetes Care Inc.

Inventor： Gary A. Hayter ,  Daniel M. Bernstein ,  Martin J. Fennell ,  Michael R. Love ,  Kenneth J. Doniger ,  Songbiao Zhang ,  Mark K. Sloan ,  Hyun Cho ,  Theodore J. Kunich ,  Jean-Pierre Cole ,  Christopher A. Thomas ,  Erwin S. Budiman ,  David L. Li ,  Royce Cheng ,  Udo Hoss

IPC: A61B5/145 ,  A61B5/01 ,  A61B5/00 ,  A61B5/1473

Abstract: Methods of compensating for ambient temperature using temperature sensors, the method comprising: sampling at a first sampling rate, with a processor, first temperature measurements from a first temperature sensor on an on-body sensor. Then determining, with a processor, first ambient-compensated temperatures from the first temperature measurements; and determining, with a processor, final ambient-compensated temperatures by applying a correction gain or factor to the first ambient-compensated temperatures. Wherein the correction gain or factor changes value at a slower rate than the sampling rate.

公开(公告)号：US20230000400A1

公开(公告)日：2023-01-05

申请号：US17942684

申请日：2022-09-12

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Mohammad E. Moein ,  Louis G. Pace ,  Udo Hoss ,  Phu X. Le ,  Samuel Mason Curry

IPC: A61B5/1486 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/1473 ,  H05K3/32

Abstract: Glucose monitoring devices and related systems and methods, the glucose monitoring devices including a sensor electronics unit having a housing and a printed circuit board disposed within the housing, a transcutaneous glucose sensor assembly, and a conductive sensor connector. The printed circuit board includes a first electrical contact, the transcutaneous glucose sensor assembly includes a distal portion having a working electrode and proximal portion having a working-electrode contact in electrical communication with the working electrode, and the conductive sensor connector electrically connects the working-electrode contact with the first electrical contact. Further, the conductive sensor connector extends through a hole in the proximal portion of the transcutaneous glucose sensor assembly and through a hole in the printed circuit board.

公开(公告)号：US20220202322A1

公开(公告)日：2022-06-30

申请号：US17567866

申请日：2022-01-03

Applicant: ABBOTT DIABETES CARE INC.

Inventor： JACOB CLARY ,  John V. LaTour ,  Udo Hoss ,  Junli Ou ,  Nolan R. Cannady

IPC: A61B5/145 ,  A61K47/58 ,  A61B17/34 ,  A61K31/573 ,  A61B5/1486 ,  A61M5/32

Abstract: The present disclosure provides therapeutic compositions and methods for delivering a therapeutic agent in close proximity to an analyte sensor. In certain embodiments, the present disclosure provides analyte sensors including one or more therapeutic agents, e.g., covalently-bound therapeutic agents. In certain embodiments, the present disclosure further provides therapeutic releasing compositions and methods of delivering such therapeutic releasing compositions.