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公开(公告)号：US20150352264A1
公开(公告)日：2015-12-10
申请号：US14298144
申请日：2014-06-06
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Julia C. Fox , Joel Harrington , Stephen Pacetti
CPC classification number: A61L31/14 , A61L31/06 , A61L31/10 , A61L31/148 , A61L31/16 , A61L31/18 , C08L53/02
Abstract: This invention is directed to vascular stents that can be visualized in vivo through the use of fluorescent imaging.
Abstract translation: 本发明涉及通过使用荧光成像在体内可视化的血管支架。
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公开(公告)号：US20150290002A1
公开(公告)日：2015-10-15
申请号：US14250023
申请日：2014-04-10
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Mary Beth Kossuth , Richard J. Rapoza , Joel Harrington
CPC classification number: A61B5/4851 , A61B5/0066 , A61B5/0084 , A61B5/6852 , A61F2/91 , A61L29/146 , A61L29/18 , A61L31/146 , A61L31/18 , G01B9/02091 , H01L21/0337 , H01L21/31144
Abstract: An endoprosthesis, a method for imaging an endoprosthesis, a method of making an endoprosthesis involve a polymeric substrate that has been modified to have voids embedded within the substrate. The voids are sized to scatter optical radiation from within the substrate so that an optical coherence tomography (OCT) image can be obtained in which an interior region of the substrate can be easily differentiated from empty space and other structures that surround the endoprosthesis. The voids allow for OCT visualization of the polymeric substrate which may be difficult to visualize by other methods such as fluoroscopy.
Abstract translation: 内置假体，用于成像内假体的方法，制造内假体的方法涉及已经被修改为具有嵌入衬底内的空隙的聚合物基底。 空隙的大小适于散射来自衬底内的光辐射，使得可以获得光学相干断层摄影（OCT）图像，其中衬底的内部区域可以容易地与空间和围绕内置假体的其他结构区分开。 空隙允许聚合物基底的OCT可视化，其可能难以通过诸如荧光透视的其它方法可视化。
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23.发明申请LASER SYSTEM AND PROCESSING CONDITIONS FOR MANUFACTURING BIOABSORBABLE STENTS 审中-公开激光系统和加工条件制造生物可溶性STENTS公开(公告)号：US20140155985A1
公开(公告)日：2014-06-05
申请号：US14171686
申请日：2014-02-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Joel Harrington , Ryan Vaughan , Kevin Jow , William Pippey , Yung-Ming Chen
IPC: A61F2/90
CPC classification number: B23K26/402 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2240/001 , B23K26/0624 , B23K2103/42 , B23K2103/50
Abstract: The present invention involves laser machining polymer substrates to form a stent with laser parameters that minimize damage to the substrate in a surface region adjacent to the machined edge surface. The wavelength and pulse width are selected for this unique application and they can be controlled to minimize the surface modifications (such as voids, cracks which are induced by the laser-material interaction) which contribute to the variation in mechanical properties with distance from the edge surface, bulk mechanical properties, or a combination thereof.
Abstract translation: 本发明涉及激光加工聚合物基底以形成具有最小化与邻近加工边缘表面的表面区域中的基底的损伤的激光参数的支架。 选择波长和脉冲宽度用于这种独特的应用，并且它们可以被控制以最小化表面修饰（例如空隙，由激光 - 材料相互作用引起的裂纹），这有助于机械性能随距离边缘的距离的变化 表面，体积机械性能或其组合。
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公开(公告)号：US10525552B2
公开(公告)日：2020-01-07
申请号：US15643221
申请日：2017-07-06
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Joel Harrington , Ryan Vaughan , Kevin Jow , William Pippey , Yung-Ming Chen
IPC: A61F2/91 , B23K26/402 , B23K26/0622 , A61F2/90 , A61F2/915 , B23K103/00
Abstract: The present invention involves laser machining polymer substrates to form a stent with laser parameters that minimize damage to the substrate in a surface region adjacent to the machined edge surface. The wavelength and pulse width are selected for this unique application and they can be controlled to minimize the surface modifications (such as voids, cracks which are induced by the laser-material interaction) which contribute to the variation in mechanical properties with distance from the edge surface, bulk mechanical properties, or a combination thereof.
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公开(公告)号：US20180325707A1
公开(公告)日：2018-11-15
申请号：US15590817
申请日：2017-05-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Jana Buccola , Joel Harrington , Syed Hossainy , Mary Beth Kossuth , Annie Liu , James Oberhauser , Fuh-Wei Tang
Abstract: A method of accelerated aging of bioresorbable polymer scaffolds including exposing the scaffold to water is disclosed. The scaffold is exposed to water at a controlled temperature for a selected aging time. The functional outputs, such as radial strength, expandability, and % recoil obtained from aged scaffolds predict those of real-time aging of the scaffold. The accelerated aging factor, which is the required shelf life divided by the aging time, is significantly higher for poly(L-lactide) scaffolds tested than thermal aging.
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Patent Agency Ranking
公开(公告)号：US10004834B2
公开(公告)日：2018-06-26
申请号：US14484943
申请日：2014-09-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Faiyaz Ahmed Hossainy , John E. Papp , Joel Harrington
CPC classification number: A61L31/148 , A61F2/88 , A61F2/90 , A61F2/966 , A61F2002/826 , A61F2002/9517 , A61F2250/0018 , A61F2250/0031 , A61F2250/0039 , A61F2250/0067 , A61L31/128 , C08L67/04
Abstract: A braided polymeric scaffold, made at least in part from a bioresorbable material is deployed on a catheter that uses a push-pull mechanism to deploy the scaffold. A drug coating is disposed on the scaffold. A plurality of scaffold segments on a catheter is also disclosed.
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27.发明申请公开(公告)号：US20170112645A1
公开(公告)日：2017-04-27
申请号：US15398425
申请日：2017-01-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , Joel Harrington
IPC: A61F2/915 , B29C35/08 , B23K26/402
CPC classification number: A61F2/915 , A61F2/91 , A61F2002/91558 , A61F2002/91583 , A61F2240/001 , B23K26/38 , B23K26/402 , B23K2103/42 , B23K2103/50 , B29C35/0805 , B29C2035/0838 , B29K2067/00 , B29K2105/005 , B29K2105/258 , B29K2995/006 , B29L2031/7532
Abstract: A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength.
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公开(公告)号：US09548215B2
公开(公告)日：2017-01-17
申请号：US14250023
申请日：2014-04-10
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Mary Beth Kossuth , Richard J. Rapoza , Joel Harrington
IPC: A61F2/89 , B23K26/00 , A61F2/95 , B23K26/40 , A61B19/00 , A61B5/00 , H01L21/311 , H01L21/033 , A61L31/14 , A61L31/18 , A61F2/91 , G01B9/02
CPC classification number: A61B5/4851 , A61B5/0066 , A61B5/0084 , A61B5/6852 , A61F2/91 , A61L29/146 , A61L29/18 , A61L31/146 , A61L31/18 , G01B9/02091 , H01L21/0337 , H01L21/31144
Abstract: An endoprosthesis, a method for imaging an endoprosthesis, a method of making an endoprosthesis involve a polymeric substrate that has been modified to have voids embedded within the substrate. The voids are sized to scatter optical radiation from within the substrate so that an optical coherence tomography (OCT) image can be obtained in which an interior region of the substrate can be easily differentiated from empty space and other structures that surround the endoprosthesis. The voids allow for OCT visualization of the polymeric substrate which may be difficult to visualize by other methods such as fluoroscopy.
Abstract translation: 内置假体，用于成像内假体的方法，制造内假体的方法涉及已经被修改为具有嵌入衬底内的空隙的聚合物基底。 空隙的大小适于散射来自衬底内的光辐射，使得可以获得光学相干断层摄影（OCT）图像，其中衬底的内部区域可以容易地与空间和围绕内置假体的其他结构区分开。 空隙允许聚合物基底的OCT可视化，其可能难以通过诸如荧光透视的其它方法可视化。
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公开(公告)号：US20160081824A1
公开(公告)日：2016-03-24
申请号：US14857635
申请日：2015-09-17
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Joel Harrington , Jill McCoy
CPC classification number: B29C65/56 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2/962 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2240/001 , B23K26/0093 , B23K26/38 , B23P11/025 , B29C71/0009 , Y10T29/49865 , Y10T29/49913 , Y10T29/49929
Abstract: A polymer scaffold is crimped to a balloon while the polymer material is in a thermodynamically unstable state, or a transient state including crimping shortly after a tube or scaffold processing step that imparts memory to the material, or shortly after rejuvenation of the scaffold.
Abstract translation: 聚合物支架卷曲到气囊，而聚合物材料处于热力学不稳定状态，或包括在管或支架加工步骤之后不久卷曲的瞬时状态，其对材料赋予记忆力，或在支架复原后不久。
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30.发明申请SHORT PULSE LASER MACHINING OF POLYMERS ENHANCED WITH LIGHT ABSORBERS FOR FABRICATING MEDICAL DEVICES 有权用于制造医疗器械的轻型吸收器的聚合物的短脉冲激光加工公开(公告)号：US20140263217A1
公开(公告)日：2014-09-18
申请号：US13802189
申请日：2013-03-13
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Stephen D. Pacetti , Joel Harrington
IPC: B23K26/38
CPC classification number: A61F2/915 , A61F2/91 , A61F2002/91558 , A61F2002/91583 , A61F2240/001 , B23K26/38 , B23K26/402 , B23K2103/42 , B23K2103/50 , B29C35/0805 , B29C2035/0838 , B29K2067/00 , B29K2105/005 , B29K2105/258 , B29K2995/006 , B29L2031/7532
Abstract: A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength.
Abstract translation: 激光加工聚合物构造物以形成支架的方法，所述支架包括生物可再吸收聚合物和在激光加工期间增加激光能量吸收的吸收体。 激光至少部分地通过多光子吸收机构切割管道，并且聚合物和吸收体具有非常低的吸光度或对于激光波长的光是透明的。
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