公开(公告)号：US20140017189A1

公开(公告)日：2014-01-16

申请号：US14030492

申请日：2013-09-18

Applicant: Colgate-Palmolive Company

Inventor： Long Pan

IPC: A61K8/26 ,  A61Q15/00

CPC classification number: A61K8/26 ,  A61K8/19 ,  A61K8/28 ,  A61Q15/00 ,  C01F7/56 ,  C01G25/00 ,  C01P2002/87

Abstract: An aluminum salt composition comprising an aluminum chlorohydrate having an aluminum to chloride molar ratio of about 0.3:1 to about 3:1, exhibiting a SEC chronatogram having a SEC Peak 4 to Peak 3 intensity ratio of at least 7, a SEC Peak 3 area of less than 5% of a total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram, and a Peak 4 intensity greater than a Peak 5 intensity in aqueous solution.

Abstract translation: 一种铝盐组合物，其包含铝与氯化物摩尔比为约0.3:1至约3:1的氯化铝水合铝，其表现出SEC峰4至峰3强度比至少为7的SEC秒表，SEC峰3区 小于SEC色谱图中峰1，2，3，4，5和6的总面积的5％，以及大于水溶液中5峰强度的峰4强度。

公开(公告)号：US12161743B2

公开(公告)日：2024-12-10

申请号：US17695100

申请日：2022-03-15

Applicant: Colgate-Palmolive Company

Inventor： Zhigang Hao ,  Chi-Yuan Cheng ,  Long Pan ,  Ravi Subramanyam

IPC: A61Q11/00 ,  A61K8/02 ,  A61K8/43 ,  A61K8/46

Abstract: The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C22H32Cl2N10][C6H12NO3S]2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.

公开(公告)号：US20240325440A1

公开(公告)日：2024-10-03

申请号：US18738288

申请日：2024-06-10

Applicant: Colgate-Palmolive Company

Inventor： Baohua Qiao ,  Long Pan ,  Gregory Szewczyk ,  Ravi Subramanyam

IPC: A61K33/42 ,  A61K6/20 ,  A61K6/74 ,  A61K8/24 ,  A61K8/27 ,  A61K9/00 ,  A61K33/30 ,  A61Q11/00 ,  A61Q15/00 ,  C01B25/37

CPC classification number: A61K33/42 ,  A61K6/20 ,  A61K6/74 ,  A61K8/24 ,  A61K8/27 ,  A61K9/0063 ,  A61K33/30 ,  A61Q11/00 ,  A61Q15/00 ,  C01B25/37 ,  A61K2800/262 ,  A61K2800/58

Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an inorganic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of making this soluble zinc polyphosphate.

公开(公告)号：US20240199295A1

公开(公告)日：2024-06-20

申请号：US18066509

申请日：2022-12-15

Applicant: Colgate-Palmolive Company

Inventor： Zhigang HAO ,  Long Pan ,  Shiyou Xu

IPC: B65D65/42 ,  B65D35/14 ,  C09D5/00 ,  C09D7/45 ,  C09D7/48 ,  C09D7/63 ,  C09D191/00

CPC classification number: B65D65/42 ,  B65D35/14 ,  C09D5/00 ,  C09D7/45 ,  C09D7/48 ,  C09D7/63 ,  C09D191/00 ,  C08K5/20

Abstract: A coated packaging article may include a packaging article and a coating. The packaging article may include a body having an interior surface, and the coating may be disposed over at least one portion of the interior surface of the body. The coating may include an edible oil and a surfactant. The coating may be in a liquid state on the interior surface inside the packaging article. The coating may be in direct contact with the at least one portion of the interior surface of the body.

公开(公告)号：US12005076B2

公开(公告)日：2024-06-11

申请号：US15538330

申请日：2014-12-26

Applicant: Colgate-Palmolive Company

Inventor： Baohua Qiao ,  Long Pan ,  Gregory Szewczyk ,  Ravi Subramanyam

IPC: A61K33/42 ,  A61K6/20 ,  A61K6/74 ,  A61K8/24 ,  A61K8/27 ,  A61K9/00 ,  A61K33/30 ,  A61Q11/00 ,  A61Q15/00 ,  C01B25/37

CPC classification number: A61K33/42 ,  A61K6/20 ,  A61K6/74 ,  A61K8/24 ,  A61K8/27 ,  A61K9/0063 ,  A61K33/30 ,  A61Q11/00 ,  A61Q15/00 ,  C01B25/37 ,  A61K2800/262 ,  A61K2800/58 ,  A61K33/42 ,  A61K2300/00 ,  A61K33/30 ,  A61K2300/00

Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an inorganic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of making this soluble zinc polyphosphate.

公开(公告)号：US11892435B2

公开(公告)日：2024-02-06

申请号：US16703985

申请日：2019-12-05

Applicant: Colgate-Palmolive Company

Inventor： Chi-Yuan Cheng ,  Zhigang Hao ,  Long Pan ,  Zolijargal Balsandorj

IPC: G01N33/15 ,  G01N24/08 ,  G01N31/22 ,  G01R33/465

CPC classification number: G01N31/221 ,  G01N24/08 ,  G01R33/465

Abstract: Methods for measuring pH of gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, are provided. The method may include preparing a calibration curve of a chemical species including or having an acid dissociation constant. Preparing the calibration curve may include plotting a chemical shift of the chemical species relative to pH. The method may also include determining a chemical shift of a gel, paste, and colloid, aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, including the chemical species. The method may further include determining the pH of the gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, with the chemical shift of the product and the calibration curve.

公开(公告)号：US11344486B2

公开(公告)日：2022-05-31

申请号：US16425122

申请日：2019-05-29

Applicant: Colgate-Palmolive Company

Inventor： Baohua Qiao ,  Long Pan ,  Gregory Szewczyk ,  Ravi Subramanyam ,  Shiri Nawrocki ,  Viktor Dubovoy

IPC: A61K8/27 ,  A61K8/24 ,  A61Q15/00 ,  A61Q11/00 ,  A61K33/30 ,  A61K33/42

Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an organic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the organic zinc salt and long chain polyphosphates being mixed in amounts that provide a phosphorus to zinc mole ratio of 15:1 to about 55:1. Further provided is a method of making this soluble zinc polyphosphate.

公开(公告)号：US11065186B2

公开(公告)日：2021-07-20

申请号：US16267424

申请日：2019-02-05

Applicant: Colgate-Palmolive Company

Inventor： Shiri Nawrocki ,  Viktor Dubovoy ,  Long Pan ,  Zhigang Hao ,  Nihal Dogu

IPC: A61K8/24 ,  A61K8/19 ,  A61Q11/00

Abstract: Provided are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na5P3O10), and oral care compositions comprising the complex and uses thereof.

公开(公告)号：US10532016B2

公开(公告)日：2020-01-14

申请号：US16213871

申请日：2018-12-07

Applicant: Colgate-Palmolive Company

Inventor： Zhigang Hao ,  Dennis Zhang ,  Donghui Wu ,  Ravi Subramanyam ,  Chi-Yuan Cheng ,  Long Pan ,  Stanislav Jaracz

IPC: A61K8/58 ,  A61Q11/00 ,  A61Q17/00 ,  A61Q15/00

Abstract: Disclosed herein are zinc-amino acid-tripolyphosphate complexes, oral care and personal care compositions comprising zinc-amino acid-tripolyphosphate complexes, and methods of making and using the same.

公开(公告)号：US10524995B2

公开(公告)日：2020-01-07

申请号：US15964193

申请日：2018-04-27

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Shaotang Yuan ,  Shira Pilch ,  James Masters ,  Zhiqiang Liu

IPC: A61K8/44 ,  A61K8/21 ,  A61K8/27 ,  A61Q11/00

Abstract: Disclosed herein are mouthwashes comprising a complex of a zinc ion source and an amino acid. Methods of making and using the compositions are also provided.