公开(公告)号：US11732289B2

公开(公告)日：2023-08-22

申请号：US17878580

申请日：2022-08-01

Applicant: Gen-Probe Incorporated

Inventor： David A. Buse ,  Norbert D. Hagen ,  David Opalsky

IPC: B01L3/00 ,  B01L7/00 ,  G01N35/04 ,  C12Q1/6806 ,  C12Q1/686

CPC classification number: C12Q1/6806 ,  B01L3/50825 ,  B01L3/565 ,  B01L7/5255 ,  C12Q1/686 ,  G01N35/04 ,  B01L3/527 ,  B01L2200/026 ,  B01L2200/0689 ,  B01L2300/046 ,  G01N2035/0418 ,  G01N2035/0436

Abstract: A receptacle distribution system includes a rotary distributor and a receptacle handoff device. The rotary distributor includes a motorized turntable with an upright wall, a distributor head for holding a receptacle, a hook configured to engage a receptacle for moving the receptacle into or out of the distributor head, and an a system for powered elevation of the distributor head. The receptacle handoff device is configured to transfer a receptacle from a first receptacle distributor to the rotary distributor and includes a receptacle yoke configured to hold a receptacle placed in the receptacle yoke with the first receptacle distributor, the receptacle yoke being rotatable between a first position to receive the receptacle and a second position to present the receptacle to the rotary distributor to enable the hook of the rotary distributor to pull the receptacle from the receptacle yoke and into the distributor head.

公开(公告)号：US11732288B2

公开(公告)日：2023-08-22

申请号：US17877832

申请日：2022-07-29

Applicant: Gen-Probe Incorporated

Inventor： David A. Buse ,  Norbert D. Hagen ,  David Opalsky

IPC: B01L3/00 ,  B01L7/00 ,  G01N35/04 ,  C12Q1/6806 ,  C12Q1/686

CPC classification number: C12Q1/6806 ,  B01L3/50825 ,  B01L3/565 ,  B01L7/5255 ,  C12Q1/686 ,  G01N35/04 ,  B01L3/527 ,  B01L2200/026 ,  B01L2200/0689 ,  B01L2300/046 ,  G01N2035/0418 ,  G01N2035/0436

Abstract: An assembly includes a bracket, a magnetic elution slot, and a reagent pack loading station. The elution slot receives a multiple receptacle device having multiple receptacles interconnected by a connecting rib defining shoulders along either side of the receptacle device. The elution slot includes opposed walls attached to the bracket below a top surface of the bracket with the opposed walls disposed on either side of a slot formed in the bracket. The downwardly facing shoulders of the receptacle device are supported on the top surface of the bracket on opposed sides of the slot, and one or more magnets are attached to or embedded in one or both walls. The reagent pack loading station holds a multi-well reagent pack such that the wells of the reagent pack are accessible by a pipettor, and the reagent pack holding station includes spaced apart hold down features extending above the top surface of the bracket.

公开(公告)号：USD982177S1

公开(公告)日：2023-03-28

申请号：US29751801

申请日：2020-09-23

Applicant: GEN-PROBE INCORPORATED

Designer： Byron J. Knight ,  David A. Buse ,  David Opalsky ,  Norbert D. Hagen ,  Tyler Moore ,  Anita Prasad ,  Bruce Richardson

公开(公告)号：US11285486B2

公开(公告)日：2022-03-29

申请号：US15934758

申请日：2018-03-23

Applicant: Gen-Probe Incorporated

Inventor： David A. Buse

IPC: B01L3/00 ,  C12Q1/6806 ,  B01L9/06 ,  C12Q1/686 ,  B01L3/02 ,  C12Q1/68 ,  B01L9/00

Abstract: A cover assembly may include a tray assembly frame, a first cover supported by the tray assembly frame, the first cover extending in a first plane and defining one or more first openings; a second cover supported by the tray assembly frame, the second cover extending in a second plane and defining one or more second openings, wherein the first and second planes are different planes, and wherein the second cover is disposed above the first cover. The cover assembly may include one or more tray holders, each tray holder being configured to hold at least one tray in an upright orientation, wherein each tray holder is moveable between an open position and a closed position, the tray holders being accessible for loading or removing the trays in the open position, and the tray holders being positioned beneath the first and second covers in the closed position.

公开(公告)号：USD940305S1

公开(公告)日：2022-01-04

申请号：US29678153

申请日：2019-01-25

Applicant: GEN-PROBE INCORPORATED

Designer： David A. Buse ,  Byron J. Knight

公开(公告)号：USD908240S1

公开(公告)日：2021-01-19

申请号：US29735363

申请日：2020-05-20

Applicant: GEN-PROBE INCORPORATED

Designer： David A. Buse

公开(公告)号：US10711297B2

公开(公告)日：2020-07-14

申请号：US15675206

申请日：2017-08-11

Applicant: GEN-PROBE INCORPORATED

Inventor： David A. Buse ,  David Opalsky ,  Jason F. Rhubottom ,  Norbert D. Hagen ,  Jennifer L. Tidd

IPC: C12Q1/68 ,  B01L3/00 ,  B01L7/00 ,  G01N35/04 ,  C12Q1/6806 ,  C12Q1/686

Abstract: An automated method for analyzing a plurality of samples within a housing of a self-contained system. The system is loaded with a plurality of samples, after which a first assay is performed on a first sample subset and a second assay performed on a second sample subset. The two assays include exposing the samples to a target capture reagent having a solid support for directly or indirectly immobilizing a target nucleic acid that may be present in one or more of the samples. The two assays may be performed with the same or different target capture reagents and target nucleic acids, but the receptacles for performing the exposing step have substantially identical geometries. Following the exposing step, an amplification reaction for amplifying a region of the target nucleic acid is performed with each sample. The amplification reactions of the two assays are performed in receptacles having different geometries.

公开(公告)号：US12006930B2

公开(公告)日：2024-06-11

申请号：US17608456

申请日：2020-04-22

Applicant: GEN-PROBE INCORPORATED

Inventor： David H. Combs ,  Ayra A. Baker ,  Norbert D. Hagen ,  David A. Buse

IPC: F04B49/025 ,  F04B37/14 ,  F04B45/02 ,  F04B49/03 ,  F04B53/20

CPC classification number: F04B49/025 ,  F04B37/14 ,  F04B45/02 ,  F04B49/03 ,  F04B53/20

Abstract: A system for managing liquid waste includes a first liquid container that receives waste liquid, a liquid transfer pump fluidly connected to the first liquid container; and a second liquid container fluidly connectable to the liquid transfer pump. The liquid transfer pump is can be selectively activated to transfer liquid waste from the first liquid container to the second liquid container when the second liquid container is fluidly connected to the liquid transfer pump. A method for managing liquid waste includes the steps of receiving waste liquid into a first liquid container, monitoring the amount of liquid in the first container, connecting a second liquid container to a liquid transfer pump that is connected to the first liquid container, after the amount of liquid received into the first liquid container reaches a predefined level, transferring liquid from the first liquid container into the second liquid container with the liquid transfer pump, and removing liquid transferred to the second liquid container.

公开(公告)号：US11840722B2

公开(公告)日：2023-12-12

申请号：US17146110

申请日：2021-01-11

Applicant: Gen-Probe Incorporated

Inventor： David A. Buse ,  David Opalsky ,  Jason F. Rhubottom ,  Norbert D. Hagen ,  Jennifer L. Tidd

IPC: C12Q1/6806 ,  G01N35/04 ,  B01L3/00 ,  B01L7/00 ,  C12Q1/686

CPC classification number: C12Q1/6806 ,  B01L3/50825 ,  B01L3/565 ,  B01L7/5255 ,  C12Q1/686 ,  G01N35/04 ,  B01L3/527 ,  B01L2200/026 ,  B01L2200/0689 ,  B01L2300/046 ,  G01N2035/0418 ,  G01N2035/0436

Abstract: A diagnostic system is configured to perform first and second, different nucleic acid amplification reactions. The system includes a bulk reagent container compartment configured to store first bulk reagent container containing a first bulk reagent for performing sample preparation processes with a first subset and a second subset of a plurality of samples and a second bulk reagent container containing a second bulk reagent for performing the first nucleic acid amplification reaction. The system includes a unit-dose reagent compartment storing a unit-dose reagent pack including unit-dose reagents for performing the second nucleic acid amplification reaction. The system is configured to perform the sample preparation process using the first bulk reagent on the first and second subsets of the samples, perform the first nucleic acid amplification reaction using the second bulk reagent on the first subset of the samples, and perform the second nucleic acid amplification reaction using the unit-dose reagents on the second subset of the samples.

公开(公告)号：US11834701B2

公开(公告)日：2023-12-05

申请号：US17878491

申请日：2022-08-01

Applicant: Gen-Probe Incorporated

Inventor： David A. Buse ,  Norbert D. Hagen ,  David Opalsky

IPC: B01L3/00 ,  B01L7/00 ,  G01N35/04 ,  C12Q1/6806 ,  C12Q1/686

CPC classification number: C12Q1/6806 ,  B01L3/50825 ,  B01L3/565 ,  B01L7/5255 ,  C12Q1/686 ,  G01N35/04 ,  B01L3/527 ,  B01L2200/026 ,  B01L2200/0689 ,  B01L2300/046 ,  G01N2035/0418 ,  G01N2035/0436

Abstract: A reagent pack changer includes a reagent pack input device, a reagent pack storage compartment, a reagent pack storage carousel disposed within the storage compartment, and a rotary distributor. The input device includes a reagent pack input carousel rotatable about an axis of rotation, with reagent pack stations for holding reagent packs disposed around the axis of rotation of the carousel. The reagent pack storage carousel is rotatable about an axis of rotation with reagent pack stations for holding reagent packs disposed around the axis of rotation. The rotary distributor is configured to move a reagent pack between the reagent pack input carousel and the reagent pack storage carousel.