公开(公告)号：US20070185176A1

公开(公告)日：2007-08-09

申请号：US10588554

申请日：2005-02-06

Applicant: Joel Van Gelder ,  Yochai Basel ,  Boris Kraiz ,  Orly Mouallem ,  Daphna Miron ,  Nina Gur-Arie ,  Joseph Klein

Inventor： Joel Van Gelder ,  Yochai Basel ,  Boris Kraiz ,  Orly Mouallem ,  Daphna Miron ,  Nina Gur-Arie ,  Joseph Klein

IPC: A61K31/425

CPC classification number: A61K31/415 ,  A61K31/136 ,  A61K31/16 ,  A61K31/185 ,  A61K31/21

Abstract: The invention provides heparanase inhibitors suitable for treatment of diseases and disorders caused by or associated with heparanase catalytic activity such as cancer, inflammatory disorders and autoimmune diseases.

Abstract translation: 本发明提供了适用于治疗由肝素酶催化活性引起的或与肝素酶催化活性相关的疾病和病症的肝素酶抑制剂，例如癌症，炎症性疾病和自身免疫性疾病。