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    Device and method for pathogen inactivation of therapeutic fluids with sterilizing radiation
    22.
    发明授权
    Device and method for pathogen inactivation of therapeutic fluids with sterilizing radiation 有权
    用灭菌辐射使病原体灭活治疗液的装置和方法

    公开(公告)号：US06596230B1

    公开(公告)日：2003-07-22

    申请号：US09494338

    申请日：2000-01-28

    Applicant: Lecon Woo ,  Daniel R. Boggs ,  Shmuel Sternberg ,  Craig Sandford ,  Atul Khare ,  Julian Breillatt

    Inventor： Lecon Woo ,  Daniel R. Boggs ,  Shmuel Sternberg ,  Craig Sandford ,  Atul Khare ,  Julian Breillatt

    IPC: A61L208

    CPC classification number: A61M1/3681 ,  A61L2/0011 ,  A61L2/10 ,  A61M1/0281 ,  A61M2202/0415 ,  A61M2205/053

    Abstract: A device and method for inactivating pathogens in therapeutic fluids with sterilizing radiation in a continuous thin fluid flow arrangement that exhibits radiation dose uniformity for fluids having high optical densities. Radiation dose uniformity is achieved in part through a “carrying” mechanism that moves or carries the fluid, thereby eliminating a channel flow velocity profile where flow volumes near the channel walls run the risk of overexposure to the radiation due to very large residence times within the channel. The device comprises a relatively flat belt chamber (22) connected to a fluid flow through an inlet (24) and an outlet (26) on the belt chamber (22). The belt chamber (22) has a top surface (28) and a bottom surface (30). A radiation permeable plate (32) is disposed adjacent the top surface (28) of the belt chamber (22) and is in contact with the belt chamber (22). A radiation source (42) is provided adjacent to the plate (32) adjacent to a side opposite the belt chamber (22). A belt (34) having a plurality of flexible vanes (36) is disposed adjacent the bottom surface (30) of the belt chamber (22) such that the vanes (36) make contact with the belt chamber (22). The belt is driven by a roller mechanism (38) in the direction of the fluid flow. As the fluid flows through the belt chamber (22), the flexible vanes (36) provide a squeegee-like mechanism to move the fluid through the belt chamber (22) in discrete packets (40) defined by a pair of vanes (36). As the packets of fluid move through the belt chamber, they are exposed to sterilizing radiation passing through the plate (32).

    Abstract translation: 一种在具有对具有高光密度的流体显示辐射剂量均匀性的连续薄流体流动布置中灭菌治疗性流体中的灭菌辐射的装置和方法。 辐射剂量均匀性部分地通过移动或携带流体的“携带”机构实现，从而消除了通道流速分布，其中通道壁附近的流量具有过度暴露于辐射的风险，这是由于内部的非常大的停留时间 渠道。 该装置包括连接到通过入口（24）的流体流和带室（22）上的出口（26）的相对平坦的带室（22）。 带室（22）具有顶表面（28）和底表面（30）。 辐射透射板（32）邻近带室（22）的顶表面（28）设置并与带室（22）接触。 辐射源（42）邻近于与带室（22）相对的一侧邻近板（32）设置。 具有多个柔性叶片（36）的带（34）邻近带室（22）的底表面（30）设置，使得叶片（36）与带室（22）接触。 皮带由辊机构（38）沿着流体流动的方向驱动。 当流体流过皮带室（22）时，柔性叶片（36）提供刮板状机构，以使流体通过一对叶片（36）限定的离散的分组（40）移动通过皮带室（22） 。 当流体包装移动通过皮带室时，它们暴露于穿过板（32）的灭菌辐射。

    Blend of ethylene and &agr;-olefin copolymers obtained using a metallocene catalyst for fabricating medical films and tubings
    24.
    发明授权
    Blend of ethylene and &agr;-olefin copolymers obtained using a metallocene catalyst for fabricating medical films and tubings 失效
    使用金属茂催化剂获得的乙烯和α-烯烃共聚物的共混物用于制造医疗膜和管

    公开(公告)号：US06372848B1

    公开(公告)日：2002-04-16

    申请号：US09685651

    申请日：2000-10-10

    Applicant: Tahua Yang ,  Sherwin Shang ,  Joel Warren ,  Samuel Ding ,  Michael T. K. Ling ,  Lecon Woo

    Inventor： Tahua Yang ,  Sherwin Shang ,  Joel Warren ,  Samuel Ding ,  Michael T. K. Ling ,  Lecon Woo

    IPC: C08L2300

    CPC classification number: A61L29/049 ,  C08L23/0815 ,  C08L2205/02 ,  C08L2314/06 ,  C08L23/04 ,  C08L2666/04

    Abstract: The present invention provides a polymer blend for fabricating medical products. The blend has a first ethylene and &agr;-olefin copolymer obtained using a single-site catalyst present in an amount by weight of from about 0% to about 99% by weight of the blend and having a melt flow index from about 0.1 g/10 min to about 5 g/10 min, a second ethylene and &agr;-olefin copolymer obtained using a single-site catalyst and being present in an amount by weight of the blend from about 0% to about 99% and having a melt flow index from higher than about 5 g/10 min to about 20 g/10 min; and a third ethylene and &agr;-olefin copolymer obtained using a single-site catalyst and being present in an amount by weight of the blend from about 0% to about 99% and having a melt flow index greater than about 20 g/10 min.

    Abstract translation: 本发明提供了用于制造医疗产品的聚合物共混物。 该共混物具有第一种乙烯和α-烯烃共聚物，其使用单组分催化剂获得，该单位催化剂的存在量为共混物重量的约0％至约99％，熔体流动指数为约0.1g / 10 min至约5g / 10min，使用单中心催化剂获得的第二乙烯和α-烯烃共聚物，以共混物的重量计约0％至约99％存在，其熔体流动指数为 高于约5g / 10min至约20g / 10min; 和使用单中心催化剂获得的第三种乙烯和α-烯烃共聚物，其以共混物重量计约0％至约99％存在并且具有大于约20g / 10min的熔体流动指数。

    Differential thermal analysis cell
    29.
    发明授权
    Differential thermal analysis cell 失效
    差热分析电池

    公开(公告)号：US4095453A

    公开(公告)日：1978-06-20

    申请号：US772134

    申请日：1977-02-25

    Applicant: Lecon Woo

    Inventor： Lecon Woo

    IPC: G01K7/02 ,  G01K17/00 ,  G01N25/48

    CPC classification number: G01N25/4866 ,  G01K17/00 ,  G01K7/02 ,  G01N25/482

    Abstract: A heat flow type differential calorimeter uses a planar thermoelectric disc as its major heat flow path for transferring heat to the sample and reference capsules. To improve the reproducibility of the calorimeter, two small discs of a thermoelectric material capable of forming a thermocouple with the thermoelectric disc are attached thereto in face-to-face relationship. Next a thermocouple pair made of the same material as the small disc and a third material, capable of forming a thermocouple with the disc, is attached to the center of each of the small discs. This converts the usual point contact temperature sensor to a large surface area temperature sensor and hence improves the reproducibility of the thermal analyzer.

    Abstract translation: 热流型差示热量计使用平面热电盘作为将热量传递给样品和参考胶囊的主要热流路径。 为了提高量热计的再现性，能够以热电盘形成热电偶的热电材料的两个小盘以面对面的关系附接到其上。 接下来，由与小盘相同材料制成的热电偶对和能够与盘形成热电偶的第三材料附接到每个小盘的中心。 这将通常的点接触温度传感器转换成大表面温度传感器，从而提高热分析仪的再现性。

    Thermomechanical analyzer
    30.
    发明授权
    Thermomechanical analyzer 失效
    热机械分析仪

    公开(公告)号：US4019365A

    公开(公告)日：1977-04-26

    申请号：US553453

    申请日：1975-03-04

    Applicant: Lecon Woo

    Inventor： Lecon Woo

    IPC: G01N3/18 ,  G01N25/04 ,  G01N25/16

    CPC classification number: G01N3/18

    Abstract: A thermomechanical analyzer is adapted to measure stress or strain in a sample material by the use of a flat, passive spring, having a known modulus of elasticity, in conjunction with an axially displaceable shaft which mechanically links the spring and the sample together. The linkage is such that the sample under test and the spring are mechanically connected in parallel, i.e., each undergo equal displacement. A transducer senses axial displacement of the shaft such that the magnitude of the shaft displacement is related to the stress in the sample. The sample may be subjected to temperature variations during the test cycle.

    Abstract translation: 热机械分析仪适于通过使用具有已知弹性模量的扁平被动弹簧与可弹性地将弹簧和样品机械连接在一起的可轴向移动的轴来测量样品材料中的应力或应变。 该连接使得被测试样品和弹簧机械地并联连接，即每个都经历相等的位移。 传感器感测轴的轴向位移，使得轴位移的大小与样品中的应力相关。 样品在测试周期内可能受到温度变化的影响。

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