公开(公告)号：US5984853A

公开(公告)日：1999-11-16

申请号：US805296

申请日：1997-02-25

Applicant: Leif Smith

Inventor： Leif Smith

IPC: A61N5/10 ,  H01J35/32 ,  G21K5/00 ,  A61B6/12

CPC classification number: A61N5/1001 ,  H01J35/32

Abstract: A method and apparatus of creating a miniaturized source of radiation and delivering radiation to a location such as therapy location. The radiation source comprises a member made of a material emitting electrons when energy is supplied to the member. There is an electron retarding member disposed opposite the electron emitting member, and the electron retarding member is made of a material emitting ionizing radiation when electrons are retarded therein. The radiation source is further provided on an elongated member in the distal region thereof, and the elongated member is insertable into the body.

Abstract translation: 一种创建微型辐射源并将辐射传送到诸如治疗位置的位置的方法和装置。 辐射源包括当能量被供应到构件时由发射电子的材料制成的构件。 存在与电子发射部件相对设置的电子延迟部件，并且当电子被延迟时，电子阻挡部件由发射电离辐射的材料制成。 辐射源还设置在其远侧区域中的细长构件上，并且细长构件可插入身体。

公开(公告)号：US09949647B2

公开(公告)日：2018-04-24

申请号：US11628251

申请日：2005-06-01

Applicant: Leif Smith ,  Ola Hammarström ,  Per Egnelöv ,  Dan Åkerfeldt

Inventor： Leif Smith ,  Ola Hammarström ,  Per Egnelöv ,  Dan Åkerfeldt

IPC: A61B5/0215 ,  A61B5/00 ,  A61M25/09 ,  A61M25/00

CPC classification number: A61B5/0215 ,  A61B5/6851 ,  A61M25/09 ,  A61M2025/0002 ,  A61M2025/09083 ,  A61M2025/09175

Abstract: The invention relates to a sensor and guide wire assembly (21) for intravascular measurements of physiological variables in a living body, comprising a core wire (22), a first coil (23), a jacket (24), and a second coil (25). The jacket (24) comprises a first end portion (24a), which is crimped onto the core wire (22) and over which a portion of the first coil (23) is threaded, and a second end portion (24b), which is crimped onto the core wire (22) and over which a portion of the second coil (25) is threaded.

公开(公告)号：US08974398B2

公开(公告)日：2015-03-10

申请号：US12742025

申请日：2008-08-22

Applicant: Leif Smith

Inventor： Leif Smith

IPC: A61B5/00 ,  A61B5/02 ,  A61M25/00 ,  A61B5/0215 ,  H01R24/66 ,  H01R24/76 ,  A61M25/09 ,  H01R13/622 ,  H01R13/66 ,  H01R103/00

CPC classification number: A61B5/0215 ,  A61B5/0002 ,  A61B5/6851 ,  A61B2560/0214 ,  A61B2560/0443 ,  A61B2562/225 ,  A61M25/09 ,  H01R13/622 ,  H01R13/6683 ,  H01R13/6691 ,  H01R24/66 ,  H01R24/76 ,  H01R2103/00

Abstract: A transmitter unit with an attachable energy source is provided for a sensor guidewire. The transmitter unit is adapted to be connected to a proximal end of a sensor guidewire provided, at its distal end, with a sensor to measure a physiological parameter inside a patient. In some embodiments, the transmitter unit is adapted to wirelessly communicate by a communication signal with a communication unit, arranged in connection with an external device, in order to transfer measured physiological data to the external device. The attachable energy source can be a battery pack or battery holder provided with connecting electrical connecting surfaces. Preferably, the connection is protected from penetrating fluids by a protective seal.

Abstract translation: 为传感器导丝提供具有可附接能量的发射器单元。 发射器单元适于连接到传感器导丝的近端，传感器导丝在其远端处设置有用于测量患者体内生理参数的传感器。 在一些实施例中，发射机单元适于通过通信信号与通信单元进行无线通信，该通信单元与外部设备结合地布置，以将测量的生理数据传送到外部设备。 可附接能源可以是具有连接电连接表面的电池组或电池座。 优选地，通过保护性密封来保护连接不渗透流体。

公开(公告)号：US08579832B2

公开(公告)日：2013-11-12

申请号：US12739326

申请日：2008-10-24

Applicant: Pär Von Malmborg ,  Leif Smith

Inventor： Pär Von Malmborg ,  Leif Smith

IPC: A61B5/00 ,  A61B6/00 ,  A61M25/00

CPC classification number: A61B5/0215 ,  A61M25/09 ,  A61M2025/09108 ,  A61M2025/09133

Abstract: There is a sensor guide wire (1) for intravascular measurements of physiological variables in a living body. The sensor guide wire (1) comprises at least two elongate sections, a first tubular elongate section (2) being tubular in the longitudinal direction of the sensor guide wire (1), and a second elongate section (3) that is adapted to be inserted a predetermined distance (5) into said first tubular section (2), a sensor element (10) provided in the distal part of said sensor guide wire (1), for measuring the physiological variable and to generate a sensor signal in response to said variable, at least one signal transmitting cable connected to the sensor element (10) to transmit sensor signals to a male connector provided in the proximal part of said sensor guide wire (1). The tubular section (2) is provided with at least one through-going opening (4) in a direction perpendicular to the longitudinal direction of the guide wire (1) and positioned a second predetermined distance (6) from one end of the tubular section (2), wherein the guide wire (1) comprises a locking member (7) to be fitted into the opening (4) in order to join the sections (2, 3) together when the second elongate section (3) is inserted into the tubular section (2).

Abstract translation: 传感器导丝（1）用于生物体内生理变量的血管内测量。 传感器导丝（1）包括至少两个细长部分，沿着传感器导丝（1）的纵向方向管状的第一管状细长部分（2）和适于成为 将预定距离（5）插入所述第一管状部分（2）中，设置在所述传感器导丝（1）的远端部分中的传感器元件（10），用于测量生理变量并响应于 所述变量，连接到所述传感器元件（10）的至少一个信号传输电缆将传感器信号发送到设置在所述传感器导丝（1）的近端部分中的公连接器。 管状部分（2）在垂直于导丝（1）的纵向方向的方向上设置有至少一个贯穿开口（4），并且从管状部分的一端定位第二预定距离（6） （2），其中所述导丝（1）包括锁定构件（7），以在所述第二细长部分（3）插入时将所述锁定构件（7）装配到所述开口（4）中，以便将所述部分（2,3） 管状部分（2）。

公开(公告)号：US20120172731A1

公开(公告)日：2012-07-05

申请号：US13395769

申请日：2010-09-14

Applicant: Leif Smith

Inventor： Leif Smith

IPC: A61B5/0215 ,  A61B5/01 ,  A61M25/09

CPC classification number: A61B5/0215 ,  A61B5/02158 ,  A61B5/6852 ,  A61M2025/0002 ,  A61M2025/0183

Abstract: Rapid exchange guide unit comprising an elongated support member 3, and a guide wire member (11) provided with a guide wire lumen (13) having a distal guide wire opening (15) and a proximal guide wire opening (17), the guide wire lumen is arranged close to the distal end of said elongated support member, and is adapted to receive a guide wire. The rapid exchange guide unit further comprises at least one sensor (19) arranged close to the distal end of the elongated support member, and being adapted to measure a parameter in a living body, and to generate a sensor signal in dependence of the measured parameter. The sensor signal is applied to a signal processing unit adapted to process the sensor signal and to generate a processed sensor signal.

Abstract translation: 包括细长支撑构件3的快速交换引导单元和设置有具有远侧导丝开口（15）和近端导丝开口（17）的导丝管腔（13）的导丝构件（11），该导丝 管腔布置成靠近所述细长支撑构件的远端，并且适于接收导丝。 快速交换引导单元还包括至少一个布置在细长支撑构件的远端附近的传感器（19），并且适于测量活体中的参数，并且根据所测量的参数产生传感器信号 。 传感器信号被施加到适于处理传感器信号并产生经处理的传感器信号的信号处理单元。

公开(公告)号：US07967761B2

公开(公告)日：2011-06-28

申请号：US11607120

申请日：2006-12-01

Applicant: Leif Smith

Inventor： Leif Smith

IPC: A61B5/00

CPC classification number: A61B5/036 ,  A61B5/6851 ,  A61M25/09033 ,  A61M2025/0002

Abstract: A sensor and guide wire assembly (21; 41; 61; 81) for intravascular measurements of a physiological variable in a living body includes a sensor element (22; 42; 62; 82) mounted at a distal sensor portion (23; 43; 63; 83) of a guide wire (24; 44; 64; 84), wherein the sensor portion exhibits a maximal cross-sectional dimension which is larger than a maximal cross-sectional dimension of guide wire portions (28, 30; 48, 50; 68, 70) located proximally of the sensor portion.

Abstract translation: 用于生物体内生理变量的血管内测量的传感器和导丝线组件（21; 41; 61; 81）包括安装在远端传感器部分（23; 43; 43）处的传感器元件（22; 42; 62; 导线（24; 44; 64; 84）的最大横截面尺寸大于导丝部分（28,30; 48; 84）的最大截面尺寸， 50; 68,70）位于传感器部分的近侧。

公开(公告)号：US07343811B2

公开(公告)日：2008-03-18

申请号：US11359761

申请日：2006-02-23

Applicant: Lars Tenerz ,  Leif Smith

Inventor： Lars Tenerz ,  Leif Smith

IPC: A61B5/00 ,  G01L7/00

CPC classification number: A61M25/09 ,  A61B5/0215 ,  A61B5/6851 ,  A61M2025/0166 ,  A61M2025/09083 ,  G01L9/0022 ,  G01L9/06 ,  G01L19/142 ,  G01L19/147 ,  H01L2224/48091 ,  H01L2224/48137 ,  H01L2924/00014

Abstract: The invention relates to a sensor (23) adapted for a sensor and guide wire assembly for intravascular measurements in a living body, wherein the sensor (23) comprises a pressure sensitive part (24) and an electronic part (25), said pressure sensitive part (24) comprising a first chip (26) provided with at least one pressure sensitive device (27) and at least one piezoelectric element (35), and said electronic part (25) comprising a second chip (28) provided with at least one electric circuit, and wherein said pressure sensitive part (24) and electronic part (25) are spatially separated from each other and are electrically connected with at least one electrical lead (29).

Abstract translation: 本发明涉及一种适用于生物体内用于血管内测量的传感器和导丝组件的传感器（23），其中传感器（23）包括压敏部件（24）和电子部件（25），所述压敏 包括设置有至少一个压敏装置（27）和至少一个压电元件（35）的第一芯片（26）的部分（24），并且所述电子部件（25）包括至少设置有第二芯片 一个电路，并且其中所述压敏部件（24）和电子部件（25）在空间上彼此分离并且与至少一个电引线（29）电连接。

公开(公告)号：US20070220986A1

公开(公告)日：2007-09-27

申请号：US11384817

申请日：2006-03-21

Applicant: Leif Smith ,  Sauli Tulkki

Inventor： Leif Smith ,  Sauli Tulkki

IPC: G01L9/06

CPC classification number: G01L9/0025 ,  B60C23/0408 ,  G01L9/008

Abstract: A sensor and insertion assembly 2 is used for intravascular measurement of pressure in a living body. The assembly includes a sensor chip 6 having a substrate body 8 with a recess covered by a pressure sensitive film 10 thereby forming a cavity 12. A piezoelectric element, preferably in the form of a piezoelectric film 14, is arranged in connection with the pressure sensitive film, and energy is applied to the piezoelectric element such that acoustic waves are generated in the element. The piezoelectric element is arranged to generate an output signal, representing the pressure at the film, in dependence on the measured properties of the acoustic waves related to the deflection of the pressure sensitive film.

Abstract translation: 传感器和插入组件2用于血管内测量活体内的压力。 组件包括传感器芯片6，传感器芯片6具有衬底本体8，衬底本体8具有被压敏薄膜10覆盖的凹部，从而形成空腔12.压电元件优选为压电薄膜14，与压力敏感 膜和能量被施加到压电元件，使得在该元件中产生声波。 压电元件被布置成根据与压敏膜的偏转相关的声波的测量特性，产生表示膜上的压力的输出信号。

公开(公告)号：US06623418B2

公开(公告)日：2003-09-23

申请号：US09851430

申请日：2001-05-09

Applicant: Leif Smith

Inventor： Leif Smith

IPC: A61N500

CPC classification number: A61N5/1001 ,  H01J35/32 ,  H01J2235/164

Abstract: A miniaturized radiation device, having a support member in the form of a flexible sheet, and a circuit pattern of electrical contact pads and interconnecting conductor lines or leads provided on said support member. The pads are interconnected via said patterned lines. There is also a plurality of radiation chips electrically connected to selected ones of said pads. Preferably the device is wrapped around a core member, that may be a wire, such that the assembly is suitable for the insertion into a living body for the controlled administration of radiation at a therapy location.

公开(公告)号：US06241651B1

公开(公告)日：2001-06-05

申请号：US09379782

申请日：1999-08-24

Applicant: Leif Smith ,  Carolina Ribbing

Inventor： Leif Smith ,  Carolina Ribbing

IPC: A61N500

CPC classification number: A61N5/1001 ,  H01J35/32

Abstract: A method and apparatus of creating a miniaturized source of radiation and delivering radiation to a location such as a therapy location. The radiation source includes a member made of a material emitting electrons when energy is supplied to the member. There is an electron retarding member disposed opposite the electron emitting member, and the electron retarding member is made of a material emitting ionizing radiation when electrons are retarded therein. The radiation source is further provided on an elongated member in a distal region thereof, and the elongated member is insertable into the body.

Abstract translation: 一种创建微型辐射源并将辐射传送到诸如治疗位置的位置的方法和装置。 辐射源包括当能量被供应到构件时由发射电子的材料制成的构件。 存在与电子发射部件相对设置的电子延迟部件，并且当电子被延迟时，电子阻挡部件由发射电离辐射的材料制成。 辐射源还设置在其远端区域中的细长构件上，并且细长构件可插入体内。