公开(公告)号：US20220347094A1

公开(公告)日：2022-11-03

申请号：US17744189

申请日：2022-05-13

Applicant: Ocular Therapeutix, Inc.

Inventor： Charles D. Blizzard ,  Arthur Driscoll ,  Rami El-Hayek ,  Michael Goldstein ,  Joseph Iacona ,  Peter Jarrett ,  Timothy S. Jarrett ,  Erica Kahn ,  Zachary Lattrell

IPC: A61K9/00 ,  A61K9/06 ,  A61K31/4439 ,  A61K47/34 ,  A61P27/02 ,  A61K31/4427

Abstract: The invention relates to a sustained release biodegradable ocular implant containing a tyrosine kinase inhibitor dispersed in a hydrogel for the treatment of a retinal disease for an extended period of time.

公开(公告)号：US20220218643A1

公开(公告)日：2022-07-14

申请号：US17673265

申请日：2022-02-16

Applicant: OCULAR THERAPEUTIX, INC.

Inventor： Charles D. Blizzard ,  Ankita Desai ,  Arthur Driscoll ,  Michael Goldstein

IPC: A61K31/216 ,  A61P27/06 ,  A61K9/00 ,  A61K47/69 ,  A61K47/10

Abstract: The present invention relates to the treatment of ocular diseases in a human subject In particular, the invention relates to an intracameral administration of a sustained release biodegradable intracameral implant.

公开(公告)号：US20220087932A1

公开(公告)日：2022-03-24

申请号：US17483250

申请日：2021-09-23

Applicant: Ocular Therapeutix, Inc.

Inventor： Charles D. Blizzard ,  Rami El-Hayek ,  Michael Goldstein ,  Peter Jarrett ,  Andrew Vanslette

IPC: A61K9/00 ,  A61K38/13 ,  A61P27/02

Abstract: Provided herein are sustained release biodegradable intracanalicular insert comprising a hydrogel and cyclosporine, methods of treating or preventing an ocular disease in a subject in need thereof by administering such inserts as well as methods of manufacturing such inserts.

公开(公告)号：US20220087931A1

公开(公告)日：2022-03-24

申请号：US17483220

申请日：2021-09-23

Applicant: Ocular Therapeutix, Inc.

Inventor： Charles D. Blizzard ,  Rami El-Hayek ,  Michael Goldstein ,  Peter Jarrett ,  Andrew Vanslette

IPC: A61K9/00 ,  A61K47/10 ,  A61K47/22 ,  A61K38/13

Abstract: Provided herein are sustained release biodegradable intracanalicular insert comprising a hydrogel and cyclosporine, methods of treating or preventing an ocular disease in a subject in need thereof by administering such inserts as well as methods of manufacturing such inserts.

公开(公告)号：US20220079876A1

公开(公告)日：2022-03-17

申请号：US17210719

申请日：2021-03-24

Applicant: Ocular Therapeutix, Inc.

Inventor： Charles D. Blizzard ,  Arthur Driscoll ,  Rami El-Hayek ,  Michael Goldstein ,  Joseph Iacona ,  Peter Jarrett ,  Timothy S. Jarrett ,  Erica Kahn ,  Zachary Lattrell

IPC: A61K9/00 ,  A61K31/4427 ,  A61P27/02

Abstract: The invention relates to a sustained release biodegradable ocular implant containing a tyrosine kinase inhibitor dispersed in a hydrogel for the treatment of a retinal disease for an extended period of time.

公开(公告)号：US20210251893A1

公开(公告)日：2021-08-19

申请号：US17169020

申请日：2021-02-05

Applicant: Ocular Therapeutix, Inc.

Inventor： Charles D. Blizzard ,  Ankita Desai ,  Arthur Driscoll ,  Michael Goldstein

IPC: A61K9/00 ,  A61K31/5575 ,  A61K9/14 ,  C08L67/04

Abstract: The present invention relates to the treatment of ocular diseases in a human subject. In particular, the invention relates to an intracameral administration of a sustained release biodegradable intracameral implant.

公开(公告)号：US20200337989A1

公开(公告)日：2020-10-29

申请号：US16857463

申请日：2020-04-24

Applicant: Ocular Therapeutix, Inc.

Inventor： Peter Jarrett ,  Rami El-Hayek ,  Timothy S. Jarrett ,  Zachary Lattrell ,  Arthur Driscoll ,  Charles D. Blizzard

IPC: A61K9/00 ,  A61K31/4439

Abstract: Provided herein are sustained-release biodegradable ocular hydrogel implants which are useful in the treatment of certain ocular conditions.