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    Cross-Sectional Modification During Deployment of an Elongate Lung Volume Reduction Device
    25.
    发明申请
    Cross-Sectional Modification During Deployment of an Elongate Lung Volume Reduction Device 有权
    在延长肺容积减少装置的部署过程中的横断面修改

    公开(公告)号：US20150073563A1

    公开(公告)日：2015-03-12

    申请号：US14225892

    申请日：2014-03-26

    Applicant: PNEUMRX, INC.

    Inventor： Mark L. Mathis ,  Patrick Wu ,  David Lehrberg ,  Jaime Vasquez ,  Erin McGurk ,  Ronald Dieck ,  Andrew Stein

    IPC: A61B17/12 ,  A61F2/04

    CPC classification number: A61B17/12104 ,  A61B1/2676 ,  A61B17/10 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/1219 ,  A61B2017/00867 ,  A61B2017/1205 ,  A61F2/04 ,  A61F2002/043

    Abstract: Elongate implant structures can be introduced into an airway system to a target airway axial region, often to apply lateral bending and/or compression forces against the lung tissue from within the airways for an extended period of time. Structures or features of the implants may inhibit tissue reactions that might otherwise allow portions of the device to eventually traverse through the wall of the airway. The devices may enhance the area bearing laterally on the tissue of a surrounding airway lumen wall. Embodiments may have features which increase the device friction with the airway to allow the device to grip the surrounding airway as the device is deployed. An appropriate adhesive may be introduced around the device in the lung. Hydrophilic material may inhibit biofilm formation, or features which induce some tissue ingrowth (stimulation of tissue growth) may enhance implanted device supported.

    Abstract translation: 细长的植入物结构可被引入到目标气道轴向区域的气道系统中，经常在气道内长时间施加横向弯曲和/或压缩力对肺组织。 植入物的结构或特征可以抑制组织反应，否则可能会使装置的部分最终穿过气道的壁。 这些装置可以增强在周围气道腔壁的组织上横向承受的面积。 实施例可以具有增加与气道的装置摩擦的特征，以允许装置在装置展开时夹紧周围气道。 可能在肺内的装置周围引入适当的粘合剂。 亲水材料可能抑制生物膜形成，或引起一些组织向内生长（刺激组织生长）的特征可以增强植入装置的支持。

    Lung Volume Reduction Devices, Methods, and Systems
    28.
    发明申请
    Lung Volume Reduction Devices, Methods, and Systems 审中-公开

    公开(公告)号：US20190150936A1

    公开(公告)日：2019-05-23

    申请号：US16256652

    申请日：2019-01-24

    Applicant: PneumRx, Inc.

    Inventor： Mark L. Mathis ,  David Thompson ,  Nathan Aronson ,  Patrick Wu

    IPC: A61B17/12 ,  A61B17/122 ,  A61M16/20 ,  A61M16/04 ,  A61B1/267

    Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.

    Cross-sectional modification during deployment of an elongate lung volume reduction device
    29.
    发明授权
    Cross-sectional modification during deployment of an elongate lung volume reduction device 有权

    公开(公告)号：US10188398B2

    公开(公告)日：2019-01-29

    申请号：US15263195

    申请日：2016-09-12

    Applicant: PneumRx, Inc.

    Inventor： Mark L. Mathis ,  Patrick Wu ,  David Lehrberg ,  Jaime Vasquez ,  Erin McGurk ,  Ronald Dieck ,  Andrew Stein

    IPC: A61B17/12 ,  A61B1/267 ,  A61B17/10 ,  A61F2/04 ,  A61B17/00

    Abstract: Elongate implant structures can be introduced into an airway system to a target airway axial region, often to apply lateral bending and/or compression forces against the lung tissue from within the airways for an extended period of time. Structures or features of the implants may inhibit tissue reactions that might otherwise allow portions of the device to eventually traverse through the wall of the airway. The devices may enhance the area bearing laterally on the tissue of a surrounding airway lumen wall. Embodiments may have features which increase the device friction with the airway to allow the device to grip the surrounding airway as the device is deployed. An appropriate adhesive may be introduced around the device in the lung. Hydrophilic material may inhibit biofilm formation, or features which induce some tissue ingrowth (stimulation of tissue growth) may enhance implanted device supported.

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