公开(公告)号：US20100002837A1

公开(公告)日：2010-01-07

申请号：US12497437

申请日：2009-07-02

Applicant: Michael GERTNER ,  Steven D. Hansen

Inventor： Michael GERTNER ,  Steven D. Hansen

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61B6/506 ,  A61B6/508 ,  A61N5/10 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1019 ,  A61N2005/1022 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1091 ,  A61N2005/1097

Abstract: A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

Abstract translation: 描述了放射外科系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施方案中，身体的其它病症或组织用辐射剂量治疗。 在一些实施例中，目标组织基于眼睛成像被放置在全局坐标系中。 在一些实施例中，全局坐标系统内的目标组织导致基于坐标系统内的目标组织定向的自动定位系统的方向。 在一些实施例中，使用治疗计划，其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。 在一些实施方案中，使用基准标记来鉴定靶组织的位置。 在一些实施例中，描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其它治疗之前，之前或之后进行递送。

公开(公告)号：US20090161827A1

公开(公告)日：2009-06-25

申请号：US12338634

申请日：2008-12-18

Applicant: Michael Gertner ,  Mark Arnoldussen ,  Erik Chell ,  Steven D. Hansen ,  Matt Herron ,  Igor Koruga ,  Junzhong Liang

Inventor： Michael Gertner ,  Mark Arnoldussen ,  Erik Chell ,  Steven D. Hansen ,  Matt Herron ,  Igor Koruga ,  Junzhong Liang

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61F9/008 ,  A61F2009/00844 ,  A61F2009/00863 ,  A61N5/1017 ,  A61N5/1049 ,  A61N2005/1059 ,  A61N2005/1072 ,  A61N2005/1091

Abstract: Embodiments provide method and systems for determining alignment of a patient's body part, such as an eye, in an external coordinate system of a treatment or diagnostic device, such as a radiotherapy device, so as to define a reference axis for guiding device operation. Additional embodiments provide image-based methods and systems for aligning, tracking and monitoring motion of a body part and a treatment target in relation to a radiation beam axis. Particular ophthalmic embodiments provide method and systems including an eye-contact guide device and imaging system for aligning and tracking motion of an eye and ocular treatment target in relation to an orthovoltage X-ray beam axis, so as to monitor application of radiation to a lesion, such as a macular lesion of the retina. Particular methods for controlling radiation in response to motion of the target during treatment are described, such as algorithms for gating or interrupting radiation emission, both to ensure treatment goals and to avoid exposure to sensitive structures.

Abstract translation: 实施例提供了用于确定诸如眼睛的患者身体部位（例如眼睛）在诸如放射治疗装置的治疗或诊断装置的外部坐标系中的对准的方法和系统，以便限定用于引导装置操作的参考轴。 另外的实施例提供基于图像的方法和系统，用于相对于辐射束轴线对准，跟踪和监测身体部位和治疗目标的运动。 特别的眼科实施例提供了包括眼睛接触引导装置和成像系统的方法和系统，用于对准和跟踪眼睛和眼部治疗目标相对于正电压X射线束轴线的运动，以便监测辐射对病变的应用 ，如视网膜的黄斑病变。 描述了在处理期间响应于靶的运动来控制辐射的特定方法，例如用于门控或中断辐射发射的算法，以确保治疗目标并避免暴露于敏感结构。

公开(公告)号：US07496174B2

公开(公告)日：2009-02-24

申请号：US11879901

申请日：2007-07-18

Applicant: Michael Gertner ,  Steven D. Hansen ,  Erik Chell

Inventor： Michael Gertner ,  Steven D. Hansen ,  Erik Chell

IPC: A61N5/10

CPC classification number: A61N5/1049 ,  A61B6/506 ,  A61B2017/306 ,  A61F9/009 ,  A61N5/1017 ,  A61N5/103 ,  A61N2005/105 ,  A61N2005/1056 ,  A61N2005/1091

Abstract: A portable orthovoltage radiotherapy system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system.

Abstract translation: 描述了便携式正电压放射治疗系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施例中，将眼部结构置于基于眼睛成像的全局坐标系中。 在一些实施例中，全局坐标系内的目镜结构导致基于坐标系内的眼睛结构而被引导的自动定位系统的方向。

公开(公告)号：US20080212738A1

公开(公告)日：2008-09-04

申请号：US11956295

申请日：2007-12-13

Applicant: Michael GERTNER ,  Steven D. Hansen

Inventor： Michael GERTNER ,  Steven D. Hansen

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61B6/506 ,  A61B6/508 ,  A61N5/10 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1019 ,  A61N2005/1022 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1091 ,  A61N2005/1097

Abstract: A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

Abstract translation: 描述了放射外科系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施方案中，身体的其它病症或组织用辐射剂量治疗。 在一些实施例中，目标组织基于眼睛成像被放置在全局坐标系中。 在一些实施例中，全局坐标系统内的目标组织导致基于坐标系统内的目标组织定向的自动定位系统的方向。 在一些实施例中，使用治疗计划，其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。 在一些实施方案中，使用基准标记来鉴定靶组织的位置。 在一些实施例中，描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其它治疗之前，之前或之后进行递送。

公开(公告)号：US6118203A

公开(公告)日：2000-09-12

申请号：US325211

申请日：1999-06-03

Applicant: Steven D. Hansen

Inventor： Steven D. Hansen

IPC: H01J35/10 ,  H02K1/14 ,  H02K5/128 ,  H02K17/12 ,  H02K11/00 ,  H02K1/00 ,  H02K1/12 ,  H02K3/00 ,  H02K3/04

CPC classification number: H02K1/146 ,  H01J35/101 ,  H02K5/128 ,  H01J2235/1026 ,  H02K17/12

Abstract: An x-ray generating device having an improved high efficiency motor is disclosed. The x-ray generating device comprises a cathode assembly and an anode assembly arranged opposite each other in a vacuum vessel. According to the invention, the anode assembly is coupled and rotated by the rotor of a high efficiency motor which has near traditional gaps by positioning the motor stator assembly in close proximity to the rotor of the motor and applying a same potential to both the stator core and the rotor. The stator assembly further includes poly-phase stator winding coils arranged on the stator core. The coils are electrically insulated from the stator core, and they are supplied with poly-phase AC signals from a motor controller to induce magnetic interactions and rotate the rotor and the anode assembly. Thus, the present invention provides for electrical isolation between the x-ray operating potential and the reference potential of the motor controller without the need for a separate isolation transformer which negatively impacts cost, efficiency and reliability.

Abstract translation: 公开了一种具有改进的高效率电动机的X射线产生装置。 x射线产生装置包括在真空容器中彼此相对布置的阴极组件和阳极组件。 根据本发明，阳极组件通过将电动机定子组件定位在电动机的转子附近并将相同的电位施加到定子铁芯上的高效率电动机的转子上而联接并旋转，所述转子具有接近传统的间隙 和转子。 定子组件还包括布置在定子芯上的多相定子绕组线圈。 线圈与定子铁芯电绝缘，并且从电机控制器提供多相AC信号以引起磁性相互作用并使转子和阳极组件旋转。 因此，本发明提供了在x射线工作电位和电动机控制器的参考电位之间的电隔离，而不需要单独的隔离变压器，其负面地影响成本，效率和可靠性。

公开(公告)号：US5008912A

公开(公告)日：1991-04-16

申请号：US417353

申请日：1989-10-05

Applicant: George A. Farrall ,  Steven D. Hansen

Inventor： George A. Farrall ,  Steven D. Hansen

IPC: H05G1/08 ,  H05G1/54 ,  H05K9/00

CPC classification number: H05K9/0064 ,  H05G1/08 ,  H05G1/54

Abstract: An X-ray imaging system includes an X-ray tube, which is biased by a high voltage power supply connected to the tube by one or two shielded cables which have a characteristic impedance. The cables are coupled to the X-ray tube by a resistance which is substantially equal to the characteristic impedance when a single cable is used or to twice the characteristic impedance when two cables are used. During a breakdown of the X-ray tube, the resistance depresses electrical current flow between the anode and the cathode of the tube. This current is in part due to the energy stored in the cable, which is not depressed by conventional current limiting circuits in the high voltage power supply.

公开(公告)号：US08837675B2

公开(公告)日：2014-09-16

申请号：US13311372

申请日：2011-12-05

Applicant: Michael Gertner ,  Erik Chell ,  Steven D. Hansen ,  Mark Arnoldussen ,  Matt Herron ,  Kuang-Hung Pan

Inventor： Michael Gertner ,  Erik Chell ,  Steven D. Hansen ,  Mark Arnoldussen ,  Matt Herron ,  Kuang-Hung Pan

IPC: A61N5/10

CPC classification number: A61N5/1049 ,  A61B6/506 ,  A61B2017/306 ,  A61F9/009 ,  A61N5/1017 ,  A61N5/103 ,  A61N2005/105 ,  A61N2005/1056 ,  A61N2005/1091

Abstract: A radiosurgery system is described that delivers a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, ocular structures are placed in a global coordinate system, based on ocular imaging, which leads to direction of an automated positioning system. In some embodiments, the position of an ocular structure is tracked and related to a radiosurgery system. In some embodiments, a treatment plan is utilized for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial aids in positioning the system. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

Abstract translation: 描述了放射外科系统，其将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施例中，眼睛结构被放置在基于眼睛成像的全局坐标系中，其导致自动定位系统的方向。 在一些实施例中，追踪眼结构的位置并与放射外科系统有关。 在一些实施方案中，治疗计划用于待治疗的特定疾病和/或要避免的结构。 在一些实施例中，基准有助于定位系统。 在一些实施例中，使用眼睛的反射来帮助定位。 在一些实施例中，描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其它治疗之前，之前或之后进行递送。

公开(公告)号：US08503609B2

公开(公告)日：2013-08-06

申请号：US12877032

申请日：2010-09-07

Applicant: Michael Gertner ,  Mark Arnoldussen ,  Erik Chell ,  Steven D. Hansen ,  Matt Herron ,  Igor Koruga ,  Junzhong Liang

Inventor： Michael Gertner ,  Mark Arnoldussen ,  Erik Chell ,  Steven D. Hansen ,  Matt Herron ,  Igor Koruga ,  Junzhong Liang

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61F9/008 ,  A61F2009/00844 ,  A61F2009/00863 ,  A61N5/1017 ,  A61N5/1049 ,  A61N2005/1059 ,  A61N2005/1072 ,  A61N2005/1091

Abstract: Embodiments provide method and systems for determining alignment of a patient's body part, such as an eye, in an external coordinate system of a treatment or diagnostic device, such as a radiotherapy device, so as to define a reference axis for guiding device operation. Additional embodiments provide image-based methods and systems for aligning, tracking and monitoring motion of a body part and a treatment target in relation to a radiation beam axis. Particular ophthalmic embodiments provide method and systems including an eye-contact guide device and imaging system for aligning and tracking motion of an eye and ocular treatment target in relation to an orthovoltage X-ray beam axis, so as to monitor application of radiation to a lesion, such as a macular lesion of the retina. Particular methods for controlling radiation in response to motion of the target during treatment are described, such as algorithms for gating or interrupting radiation emission, both to ensure treatment goals and to avoid exposure to sensitive structures.

Abstract translation: 实施例提供了用于确定诸如眼睛的患者身体部位（例如眼睛）在诸如放射治疗装置的治疗或诊断装置的外部坐标系中的对准的方法和系统，以便限定用于引导装置操作的参考轴。 另外的实施例提供基于图像的方法和系统，用于相对于辐射束轴线对准，跟踪和监测身体部位和治疗目标的运动。 特别的眼科实施例提供了包括眼睛接触引导装置和成像系统的方法和系统，用于对准和跟踪眼睛和眼部治疗目标相对于正电压X射线束轴线的运动，以便监测辐射对病变的应用 ，如视网膜的黄斑病变。 描述了在处理期间响应于靶的运动来控制辐射的特定方法，例如用于门控或中断辐射发射的算法，以确保治疗目标并避免暴露于敏感结构。

公开(公告)号：US08494116B2

公开(公告)日：2013-07-23

申请号：US12887419

申请日：2010-09-21

Applicant: Michael Gertner ,  Mark Arnoldussen ,  Erik Chell ,  Steven D. Hansen ,  Junzhong Liang

Inventor： Michael Gertner ,  Mark Arnoldussen ,  Erik Chell ,  Steven D. Hansen ,  Junzhong Liang

IPC: A61N5/10

CPC classification number: A61N5/1037 ,  A61N5/1017 ,  A61N5/103 ,  A61N5/1064 ,  A61N2005/1091

Abstract: A method, code and system for planning the treatment a lesion on or adjacent to the retina of an eye of a patient are disclosed. There is first established at least two beam paths along which x-radiation is to be directed at the retinal lesion. Based on the known spectral and intensity characteristics of the beam, a total treatment time for irradiation along each beam paths is determined. From the coordinates of the optic nerve in the aligned eye position, there is determined the extent and duration of eye movement away from the aligned patient-eye position in a direction that moves the patient's optic nerve toward the irradiation beam that will be allowed during treatment, while still maintaining the radiation dose at the patient optic nerve below a predetermined dose level.

公开(公告)号：US08306186B2

公开(公告)日：2012-11-06

申请号：US13159313

申请日：2011-06-13

Applicant: Michael Gertner ,  Steven D. Hansen

Inventor： Michael Gertner ,  Steven D. Hansen

IPC: A61N5/10 ,  A61B6/08

CPC classification number: A61N5/1067 ,  A61B6/506 ,  A61B6/508 ,  A61N5/10 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1019 ,  A61N2005/1022 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1091 ,  A61N2005/1097

Abstract: Radiosurgery systems are described that are configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, and in some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, a fiducial marker is used to identify the location of the target tissues.

Abstract translation: 描述了放射外科系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，并且在一些实施方案中，用辐射剂量治疗身体的其它病症或组织。 在一些实施例中，将目标组织放置在基于眼睛成像的全局坐标系中。 在一些实施方案中，使用基准标记来鉴定靶组织的位置。