公开(公告)号：US10509092B2

公开(公告)日：2019-12-17

申请号：US15068943

申请日：2016-03-14

Applicant: ADA Foundation

Inventor： Laurence C. Chow ,  Shozo Takagi ,  Marc Frederic Desrosiers

IPC: G01N27/00 ,  G01R33/60 ,  G01N24/10 ,  A61B6/10 ,  G01T1/04

Abstract: A dosimeter for EPR dosimetry systems includes a carbonated hydroxyapatite cement formed by mixing a cement powder and a cement liquid in a ratio of a range of about 0.5 to 5.0 powder-to-liquid ratio. The cement powder includes one or more calcium phosphate compounds and one or more carbonate compounds. The cement liquid includes a sodium phosphate solution. The cement, when irradiated by a radiation source, is capable of producing a measurable signal as a spectrally clean EPR spectrum. Furthermore, the measurable signal is proportional to the received radiation dose.

公开(公告)号：US10246540B2

公开(公告)日：2019-04-02

申请号：US15276821

申请日：2016-09-27

Applicant: ADA Foundation

Inventor： Jirun Sun

IPC: C08F220/68 ,  A61K6/00 ,  C09D11/107 ,  B33Y70/00 ,  A61K6/083 ,  C08F216/12 ,  C08K3/36 ,  C09D129/10 ,  C09D133/14 ,  C09J129/10 ,  C09J133/14 ,  C08F222/10 ,  C09D11/101

Abstract: A composition of matter includes a mixture of styrene derivative monomers and methacrylate/acrylate derivative monomers, which have one or more urethane, carbamate, amide, and/or amine functional groups, and initiators, and the compositions are used to achieve composition control of the forming polymer, with the mole fraction of acrylate/methacrylate and styrene moieties in the forming polymer determined preferably by the chemistry and composition of the feeding monomers rather than the viscosity of the monomers.

公开(公告)号：US09883923B2

公开(公告)日：2018-02-06

申请号：US15613298

申请日：2017-06-05

Applicant: ADA Foundation

Inventor： Laurence C Chow ,  Shozo Takagi

IPC: A61K6/08 ,  A61F2/00 ,  A61C5/50 ,  A61K6/00

CPC classification number: A61C5/50 ,  A61K6/0038 ,  A61K6/0067 ,  A61K6/0606 ,  A61K6/0612 ,  A61K6/0625 ,  A61K6/0643 ,  A61K6/097 ,  C08L31/04 ,  C08L1/284 ,  C08L5/04 ,  C08L29/04 ,  C08L33/08 ,  C08L5/08 ,  C08L5/06

Abstract: Disclosed are endodontic filling materials and methods. A method for filling a dental root canal may include providing a hydrosetting filling material and inserting the hydrosetting filling material into the dental root canal, the material setting in the root canal to form a biocompatible filling. The hydrosetting filling material comprises a hydrogel former and a filler. The hydrogel former is at least one of a reactive organic hydrogel formers, an inorganic hydrogel formers, and a non-reactive organic hydrogel formers, and the filler is at least one of a self-hardening and a non-hardening filler. Plural filling material precursor compositions that collectively contain hydrogel formers and fillers may be provided.

公开(公告)号：US20150209249A1

公开(公告)日：2015-07-30

申请号：US14678458

申请日：2015-04-03

Applicant: ADA FOUNDATION

Inventor： Gerald L. VOGEL ,  Laurence C. CHOW ,  Shozo TAKAGI

IPC: A61K8/19 ,  A61K8/21 ,  A61Q11/00

CPC classification number: A61K8/19 ,  A61K8/21 ,  A61K8/30 ,  A61K2800/5922 ,  A61Q11/00

Abstract: Mouth rinses, dentifrices, lozenges, confections, chewing gums, and similar delivery vehicles containing non-toxic soluble calcium are used prior to administration of a fluoride-containing composition to increase the effectiveness of the fluoride therapy. An effective amount of calcium is released into the oral cavity and allowed to penetrate into the oral tissue. Calcium-bound fluoride deposits form in the oral tissue upon subsequent administration of the fluoride-containing composition to provide increased salivary, plaque and oral tissue fluoride concentrations.

Abstract translation: 在给予含氟化合物组合物以提高氟化物治疗的有效性之前，使用口腔清洗剂，洁牙剂，锭剂，糖果，口香糖和含有无毒可溶性钙的类似递送载体。 将有效量的钙释放到口腔中并允许渗入口腔组织。 随后施用含氟化物的组合物，在口腔组织中形成钙结合的氟化物沉积物，以提供增加的唾液，斑块和口服组织氟化物浓度。