Deep rolling roller head of a deep rolling tool
    31.
    发明授权
    Deep rolling roller head of a deep rolling tool 失效
    深辊滚动工具的深轧辊头

    公开(公告)号:US07168278B2

    公开(公告)日:2007-01-30

    申请号:US10526204

    申请日:2003-02-15

    CPC classification number: B21H7/185 B24B5/42 B24B39/04 B24B39/045 Y10T29/17

    Abstract: The invention relates to a deep rolling roller head (1) of a deep rolling tool for deep rolling radii or recesses (22) on the main and lifting bearing journals of crankshafts (21). Said deep rolling roller head is equipped with a housing (2) inside of which one or two laterally interspaced deep rolling rollers (4) are rotationally guided in a loose manner and with little play in two roller cages (5, 6). The roller cages (5, 6) are fastened to supports (15) on the face (3) of the housing (2) oriented toward the crankshaft (21). Said supports support the roller cages (5, 6) on their faces (10) oriented away from the deep rolling rollers (4) while laterally guiding them at the same time. The face (3) of the housing (2) oriented toward the crankshaft (21) is provided, on both ends thereof, with a projection (11, 12) for supporting each of the roller cages (5, 6). A fastening and guiding element (15) is provided for each roller cage (5, 6), engages inside the roller cage (5, 6), and can be fastened to one of the projections (11, 12) of the housing (2) at the same time.

    Abstract translation: 本发明涉及一种用于在曲轴(21)的主提升轴承轴颈上的深度滚动半径或凹槽(22)的深滚动工具的深辊滚动头(1)。 所述深滚动辊头配有壳体(2),其中一个或两个横向间隔深的滚动辊(4)以松散的方式被旋转地引导并且在两个滚筒保持架(5,6)中几乎不起作用。 辊笼(5,6)被紧固到朝向曲轴(21)定向的壳体(2)的面(3)上的支撑件(15)上。 所述支撑件支撑位于其远离深轧辊(4)的表面(10)上的辊笼(5,6),同时横向地引导它们。 在壳体(2)的朝向曲轴(21)的面(3)的两端设置有用于支撑各个滚笼(5,6)的突起(11,12)。 为每个滚子保持架(5,6)提供一个紧固和引导元件(15),它们接合在滚子保持器(5,6)内部,并且可以紧固到壳体(2)的一个突起(11,12) ) 与此同时。

    Deep-rolling roller head
    32.
    发明授权
    Deep-rolling roller head 失效
    深辊辊头

    公开(公告)号:US07100413B2

    公开(公告)日:2006-09-05

    申请号:US10505184

    申请日:2003-05-02

    CPC classification number: B24B5/42 B24B39/045 Y10T29/17

    Abstract: The invention relates to a deep-rolling roller head (1) of a deep rolling tool with deep-rolling rollers (2) that are rotatably mounted in roller cages (3) and are at a distance (4) from the center (5) of the underside (6) of the housing (7) of the deep-rolling roller head (1) and are supported on the front (8) at the end of the long leg (9) of two L-shaped holding devices (11) that can be adjusted and fixed in the direction of the center (5). A first screw (13) enters an oblong hole (12) in each long leg (9) to hold the L-shaped holding device (11) on the underside of the housing (7) while a second screw (14) passes through a bore (15) in each short leg (10 and enters a bore (26) in the adjoining front (21) of the housing (7), being provided in order to adjust the precise position of the roller cage (3) relative to the center (5). With the L-shaped holding device (11) shown on the left half of the drawing the front (25) adjoining the underside (6) is at a predetermined first distance (18) from the center (5) over a segment (17) of its length. The appertaining short leg (10) is supported over a segment of its inside on the segment (17) of the housing (7). The front (8) of the appertaining long leg (9) is at a predetermined distance (17) from the segment (17).

    Abstract translation: 本发明涉及一种具有可旋转地安装在辊笼(3)中并与中心(5)相距一定距离(4)的深辊轧机(2)的深轧机的深辊辊头(1) (1)的壳体(7)的下侧(6)的两个L形保持装置(11)的长腿(9)的端部被支撑在前部(8)上 )可以在中心(5)的方向上调节和固定。 第一螺钉(13)进入每个长腿(9)中的长孔(12),以将L形保持装置(11)保持在壳体(7)的下侧,同时第二螺钉(14)穿过 每个短腿(10)中的孔(15)在壳体(7)的相邻前部(21)中进入孔(26),以便相对于所述壳体(7)调整所述滚子保持架(3)的精确位置 在左图所示的L形保持装置(11)中,与下侧(6)相邻的前(25)与中心(5)相距预定的第一距离(18)处于中心(5) 其长度的段(17),所述短脚(10)的支撑在所述壳体(7)的所述段(17)上的内部的一段上,所述长腿(9)的前部(8) 与所述段(17)处于预定距离(17)。

    Hard-rolling roller head pertaining to a hard-rolling tool
    33.
    发明授权
    Hard-rolling roller head pertaining to a hard-rolling tool 失效
    硬质轧辊头硬质轧制工具

    公开(公告)号:US07100412B2

    公开(公告)日:2006-09-05

    申请号:US10504107

    申请日:2003-04-25

    CPC classification number: B21H7/185 B24B5/42 B24B39/04 B24B39/045 Y10T29/17

    Abstract: The invention relates to a deep-rolling roller head (1) of a deep-rolling tool for the deep rolling of radii or undercuts (22) on the main and stroke journals of crankshafts (21), with a housing (2) in which one or two deep-rolling rollers are tracked with little clearance and are loosely rotatable in a roller cage (5) at a lateral distance from each other. The roller cage (5) is attached to underside (3) of the housing (2) towards the crankshaft (21) by means of pins (15) which support the roller cage (5) on its face (10) away from the deep-rolling rollers (4) and at the same time track them laterally. The housing (2) is provided with a projection (11, 12) for the support of the roller cage (5) on either end of its underside (3) towards the crankshaft (21). Pins (15) serving as fastening and tracking elements of the roller cage (5) are provided and engage the roller cage (5).

    Abstract translation: 本发明涉及一种用于在曲轴(21)的主行程和行程轴颈上深度滚动半径或底切(22)的深轧辊头(1),其中壳体(2) 一个或两个深辊滚子以很小的间隙被跟踪,并且在滚子保持器(5)中以彼此横向的距离松动地旋转。 滚轮保持架(5)通过在其表面(10)上远离深度支撑滚子保持架(5)的销(15)而附接到壳体(2)的下侧(3) 滚筒(4),同时跟踪它们。 壳体(2)设置有用于在其下侧(3)的任一端向着曲轴(21)支撑滚子保持架(5)的突起(11,12)。 提供用作滚子保持架(5)的紧固和跟踪元件的引脚(15)并与滚子保持器(5)接合。

    1-phenyl-2-aminocarbonylindole compounds, preparation thereof and
pharmaceutical compositions containing them
    34.
    发明授权
    1-phenyl-2-aminocarbonylindole compounds, preparation thereof and pharmaceutical compositions containing them 失效
    1-苯基-2-氨基羰基吲哚化合物,其制备方法和含有它们的药物组合物

    公开(公告)号:US4814345A

    公开(公告)日:1989-03-21

    申请号:US123201

    申请日:1987-11-20

    CPC classification number: C07D209/42

    Abstract: Novel 1-phenyl-2-aminocarbonylindole compounds are disclosed having the general formula I ##STR1## wherein R.sub.1 is an aliphatic or aromatic acyl group or an optionally substituted benzyl group; R.sub.2 is hydrogen or a lower alkyl radical; R.sub.3 is a hydrogen, a halogen, a lower alkyl radical, or a lower alkoxy radical; R.sub.4 is hydrogen, a halogen, a lower alkyl radical, or a lower alkoxy radical; R.sub.5 has the significance given R.sub.3 ; R.sub.6 has the significance given for R.sub.4, or R.sub.6 is nitro or trifluoromethyl; R.sub.7 and R.sub.8 each represent hydrogen or a lower alkyl radical, or together with a nitrogen atom form a heterocyclic group; and Z signifies an alkylene chain optionally substituted by hydroxy or acyloxy. The compounds have pharmacological, in particular antiarrhythmic, properties.

    Abstract translation: 公开了具有通式I的新型1-苯基-2-氨基羰基吲哚化合物,其中R 1是脂族或芳族酰基或任选取代的苄基; R2是氢或低级烷基; R3是氢,卤素,低级烷基或低级烷氧基; R4是氢,卤素,低级烷基或低级烷氧基; R5具有给定R3的意义; R6对R4具有重要意义,或R6是硝基或三氟甲基; R7和R8各自表示氢或低级烷基,或与氮原子一起形成杂环基; Z表示任选被羟基或酰氧基取代的亚烷基链。 这些化合物具有药理学,特别是抗心律不齐的特性。

    1-Phenyl-2-aminocarbonylindole compounds, preparation thereof and
pharmaceutical compositions containing them
    35.
    发明授权
    1-Phenyl-2-aminocarbonylindole compounds, preparation thereof and pharmaceutical compositions containing them 失效
    1-苯基-2-氨基羰基吲哚化合物,其制备方法和含有它们的药物组合物

    公开(公告)号:US4803198A

    公开(公告)日:1989-02-07

    申请号:US885684

    申请日:1986-07-15

    CPC classification number: C07D209/42

    Abstract: New 1-phenyl-2-aminocarbonylindole compounds are described which have the general formula I ##STR1## where R.sub.1 is a hydrogen atom, or a lower alkyl, alkenyl, cycloalkylalkyl radical, R.sub.2 is a hydrogen atom or a lower alkyl radical, R.sub.3 is a hydrogen or halogen atom, or a lower alkyl, hydroxyl or lower alkoxy radical, R.sub.4 is a hydrogen or halogen atom, or a lower alkyl, hydroxyl or lower alkoxy radical, or, if R.sub.3 is a hydrogen atom, R.sub.4 may be a nitro or trifluoromethyl radical, or R.sub.3 and R.sub.4 together denote a methylenedioxy or ethylenedioxy radical, R.sub.5 has the meanings given for R.sub.3, R.sub.6 has the meanings given for R.sub.4, R.sub.7 is a hydrogen atom or, if R.sub.5 and R.sub.6 are lower alkoxy radicals, R.sub.7 may also be a lower alkoxy radical, R.sub.8 and R.sub.9 are each a hydrogen atom or a lower alkyl radical or, together with the nitrogen atom, form a heterocyclic group, and Z is an alkylene chain which is optionally substituted by hydroxyl. The compounds have pharmaceutical properties, in particular antiarrhythmic properties. The compounds may be in the form of the free bases or acid addition salts. Pharmaceutical compositions containing these compounds are described as is a method of preparing them.Valuable intermediates for the production of these compounds and methods of preparing the intermediates are also described.

    Abstract translation: 描述了具有通式Ⅰ的新的1-苯基-2-氨基羰基吲哚化合物,其中R 1是氢原子,或低级烷基,烯基,环烷基烷基,R 2是氢原子或低级烷基,R 3 是氢或卤素原子,或低级烷基,羟基或低级烷氧基,R4是氢或卤素原子,或低级烷基,羟基或低级烷氧基,或者如果R3是氢原子,R4可以是 硝基或三氟甲基,或R 3和R 4一起表示亚甲二氧基或亚乙二氧基,R 5具有R 3的含义,R 6具有对R 4的定义,R 7是氢原子,或者如果R 5和R 6是低级烷氧基,则R 7 也可以是低级烷氧基,R 8和R 9各自为氢原子或低级烷基,或者与氮原子一起形成杂环基,Z为任选被羟基取代的亚烷基链。 这些化合物具有药物性质,特别是抗心律失常性质。 化合物可以是游离碱或酸加成盐的形式。 含有这些化合物的药物组合物被描述为制备它们的方法。 还描述了制备这些化合物的有价值的中间体和制备中间体的方法。

    N-Amino alkyl indole compounds compositions containing same, and a
method of using same in therapy of disorders of gastrointestinal
motility
    36.
    发明授权
    N-Amino alkyl indole compounds compositions containing same, and a method of using same in therapy of disorders of gastrointestinal motility 失效
    包含其的N-氨基烷基吲哚化合物组合物及其在胃肠蠕动障碍治疗中的应用方法

    公开(公告)号:US4374846A

    公开(公告)日:1983-02-22

    申请号:US172023

    申请日:1980-07-24

    CPC classification number: C07D209/42

    Abstract: Novel N-amino alkyl indole compounds are disclosed. These compounds correspond to the Formula I ##STR1## In said Formula R.sub.1 indicates the hydrogen atom, an alkyl group with 1 to 4 carbon atoms, which may be substituted by a phenyl group, or the acetyl group;R.sub.2 indicates the hydroxy carbonyl group, an alkoxy carbonyl group with 1 to 4 alkyl carbon atoms, the cyano group, the amino carbonyl group, a mono-alkyl amino carbonyl group with 1 to 4 alkyl carbon atoms, or a di-alkyl amino carbonyl group with 1 to 4 alkyl carbon atoms, with the proviso that, when R.sub.2 is the hydroxy carbonyl group, then R.sub.1 is other than the hydrogen atom;A indicates an alkylene group with 2 to 5 carbon atoms;R.sub.3 and R.sub.4 are the same or different substituents and indicate the hydrogen atom, an alkyl group with 1 to 4 carbon atoms, or R.sub.3 and R.sub.4 are an alkylene group forming, together with the nitrogen atom to which they are attached, a heterocyclic ring with 5 to 7 ring members; andR.sub.5 and R.sub.6 are the same or different substituents and indicate hydrogen and halogen atoms, alkyl groups with 1 to 3 carbon atoms, alkoxy groups with 1 to 3 carbon atoms, or one of said substituents R.sub.5 and R.sub.6 being the nitro group or the trifluoro methyl group while the other one is the hydrogen atom.The acid addition salts of said compounds are also disclosed.The above mentioned novel N-amino alkyl indole compounds have a favorable effect upon the motility of the gastro-intestinal tract.The compounds are obtained, for instance, by reacting the alkali metal salts of a corresponding indole compound which is unsubstituted at its nitrogen atom, with a halogeno alkyl amine.

    Abstract translation: 公开了新的N-氨基烷基吲哚化合物。 这些化合物对应于式I的化合物。式中R1表示氢原子,可被苯基取代的具有1至4个碳原子的烷基或乙酰基; R2表示羟基羰基,具有1-4个烷基碳原子的烷氧基羰基,氰基,氨基羰基,具有1-4个烷基碳原子的单烷基氨基羰基或二烷基氨基羰基 具有1至4个烷基碳原子,条件是当R 2是羟基羰基时,则R 1不是氢原子; A表示碳原子数2〜5的亚烷基, R3和R4是相同或不同的取代基,表示氢原子,具有1至4个碳原子的烷基,或者R3和R4是与它们所连接的氮原子一起形成的亚烷基, 5至7名成员; 并且R 5和R 6是相同或不同的取代基,并且表示氢和卤素原子,具有1至3个碳原子的烷基,具有1至3个碳原子的烷氧基,或所述取代基R 5和R 6中的一个是硝基或三氟 甲基,而另一个是氢原子。 还公开了所述化合物的酸加成盐。 上述新型N-氨基烷基吲哚化合物对胃肠道的运动具有有利的作用。 化合物例如通过使在其氮原子上未取代的相应吲哚化合物的碱金属盐与卤代烷基胺反应而获得。

    1-Benzoxepin-5 (2H)-one derivatives and pharmaceutical compositions
    37.
    发明授权
    1-Benzoxepin-5 (2H)-one derivatives and pharmaceutical compositions 失效
    1-苯并恶庚英-5(2H) - 酮衍生物和药物组合物

    公开(公告)号:US4279905A

    公开(公告)日:1981-07-21

    申请号:US173076

    申请日:1980-07-28

    CPC classification number: C07D313/08

    Abstract: Novel, 3-amino-1-benzoxepin-5 (2H)-one derivatives and methods for their production are disclosed. These derivatives correspond to the Formula I: ##STR1## wherein: R.sub.1 and R.sub.2 independently of one another arehydrogen,C.sub.1 -C.sub.5 alkyl,C.sub.1 -C.sub.5 alkyl substituted with a terminal phenyl, or a phenyl containing one or two halogens, methyl or methoxy groups, a 3,4-methylenedioxy or a 3,4-ethylenedioxy group,C.sub.2 -C.sub.5 alkyl substituted with terminal hydroxy or methoxy or,C.sub.3 -C.sub.4 alkenyl; orone of R.sub.1 and R.sub.2 are hydrogen or a C.sub.1 -C.sub.5 alkyl and the other is a C.sub.2 -C.sub.5 alkyl substituted with a terminal NR.sub.5 R.sub.6 ;R.sub.5 and R.sub.6 independently of one another are hydrogen or C.sub.1 -C.sub.5 alkyl; orR.sub.5 and R.sub.6 are together a 5 to 7 member ring, orR.sub.5 and R.sub.6 are together a 5 to 7 member ring having heterogeneous oxygen, sulfur or nitrogen;R.sub.1 and R.sub.2 are together a 5 to 7 member ring, orR.sub.1 and R.sub.2 are together a 5 to 7 member ring having heterogeneous oxygen, sulfur or NR.sub.7 ;R.sub.7 is hydrogen, methyl, benzyl or phenyl;R.sub.3 and R.sub.4 independently of one another are hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkylthio; orone of R.sub.3 and R.sub.4 is trifluoromethyl or nitro and the other is hydrogen;and the acid addition salts thereof. These compounds have a favorable effect on the treatment of spasms of the stomach-intestinal tract and, therefore, constitute the active ingredient of pharmaceutical compositions and methods for the treatment of disorders of the stomach and intestinal tract. Processes for the preparation of the derivatives and their acid addition salts and intermediate products for their preparation are also descrived.

    Abstract translation: 公开了3-氨基-1-苯并氧杂-5(2H) - 酮衍生物及其生产方法。 这些衍生物对应于式I:其中:R 1和R 2彼此独立地是氢,C 1 -C 5烷基,被末端苯基取代的C 1 -C 5烷基或含有一个或两个卤素的苯基,甲基或 甲氧基,3,4-亚甲二氧基或3,4-亚乙二氧基,被末端羟基或甲氧基取代的C 2 -C 5烷基或C 3 -C 4烯基; 或R 1和R 2中的一个为氢或C 1 -C 5烷基,另一个为被末端NR 5 R 6取代的C 2 -C 5烷基; R 5和R 6彼此独立地是氢或C 1 -C 5烷基; 或R 5和R 6一起为5至7元环,或者R 5和R 6一起为具有异质的氧,硫或氮的5至7元环; R 1和R 2一起为5至7元环,或者R 1和R 2一起为具有异质氧,硫或NR 7的5至7元环; R7是氢,甲基,苄基或苯基; R 3和R 4彼此独立地是氢,卤素,C 1 -C 4烷基,C 1 -C 4烷氧基或C 1 -C 4烷硫基; 或者R 3和R 4中的一个是三氟甲基或硝基,另一个是氢; 及其酸加成盐。 这些化合物对胃肠道痉挛的治疗具有有利的作用,因此构成了用于治疗胃肠道疾病的药物组合物和方法的活性成分。 还描述了制备衍生物及其酸加成盐和中间产物用于其制备的方法。

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