公开(公告)号：US07630755B2

公开(公告)日：2009-12-08

申请号：US11121450

申请日：2005-05-04

Applicant: Jeffrey E. Stahmann ,  John D. Hatlestad ,  Jesse W. Hartley ,  Avram Scheiner

Inventor： Jeffrey E. Stahmann ,  John D. Hatlestad ,  Jesse W. Hartley ,  Avram Scheiner

IPC: A61B5/04 ,  A61B5/02

CPC classification number: A61B5/02028 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/0215 ,  A61B5/02405 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/11 ,  A61B5/1116 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/14546 ,  A61N1/362 ,  A61N1/37247 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3481 ,  G16H40/63

Abstract: Method and systems are directed to acquiring and organizing information associated with at least one syncope event. A syncope event may be a suspected syncope event, a verified syncope event or a syncope event that is suspected and verified. Automated processes are used to collect information associated with at least one syncope event and organize the information as a syncope log entry. At least one of acquiring the information and organizing the information is performed at least in part implantably.

Abstract translation: 方法和系统旨在获取和组织与至少一个晕厥事件相关联的信息。 晕厥事件可能是疑似晕厥事件，经过验证的晕厥事件或怀疑和验证的晕厥事件。 自动进程用于收集与至少一个晕厥事件相关的信息，并将该信息组织为晕厥日志条目。 至少部分地可植入地执行获取信息和组织信息中的至少一个。

公开(公告)号：US20090198139A1

公开(公告)日：2009-08-06

申请号：US12384271

申请日：2009-04-02

Applicant: Aaron Lewicke ,  Yi Zhang ,  John D. Hatlestad

Inventor： Aaron Lewicke ,  Yi Zhang ,  John D. Hatlestad

IPC: A61B5/0205

CPC classification number: A61B5/0816 ,  A61B5/0205 ,  A61B5/1116 ,  A61B5/7264 ,  G06F19/00

Abstract: A device and method can monitor or trend a patient's respiration rate measurements according to the time of day. The device, which may be implantable or external, collects and classifies respiration rate measurements over time. The trended information about particular classes of respiration rate measurements is then communicated to a remote external device, which in turn provides an indication of heart failure decompensation. Examples of classes of respiration rate measurements include a daily maximum respiration rate value, a daily minimum respiration rate value, a daily maximum respiration rate variability value, a daily minimum respiration rate variability value, and a daily central respiration rate value. These respiration rate measurements can be further classified into daytime or nighttime respiration rate measurements.

公开(公告)号：US20090177702A1

公开(公告)日：2009-07-09

申请号：US12403880

申请日：2009-03-13

Applicant: Jeffrey E. Stahmann ,  John D. Hatlestad ,  Jesse W. Hartley ,  Quan Ni ,  Kent Lee

Inventor： Jeffrey E. Stahmann ,  John D. Hatlestad ,  Jesse W. Hartley ,  Quan Ni ,  Kent Lee

IPC: G06F17/30 ,  G06F3/048

CPC classification number: A61B5/0803 ,  A61B5/02405 ,  A61N1/3601

Abstract: An event-based approach to collecting and organizing information associated with events affecting respiration is presented. The detection or prediction of an event affecting the respiration of a patient initiates acquisition of information associated with the event. The respiratory logbook system acquires information associated with the event during the event and during intervals proximate in time to the event. The information is organized as a respiratory log entry. The user can access the information by operating a user interface. The information may be presented in textual or graphical form.

Abstract translation: 提出了一种基于事件的方法来收集和组织与影响呼吸的事件相关的信息。 影响患者呼吸的事件的检测或预测启动与事件相关联的信息的获取。 呼吸记录系统在事件期间以及在时间上接近事件的间隔期间获取与事件相关联的信息。 信息被组织为呼吸日志条目。 用户可以通过操作用户界面访问信息。 信息可以以文本或图形形式呈现。

公开(公告)号：US07510531B2

公开(公告)日：2009-03-31

申请号：US10824776

申请日：2004-04-15

Applicant: Kent Lee ,  John D. Hatlestad ,  Qingsheng Zhu ,  Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Quan Ni

Inventor： Kent Lee ,  John D. Hatlestad ,  Qingsheng Zhu ,  Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Quan Ni

IPC: A61B5/08

CPC classification number: A61B5/7264 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/08 ,  A61B5/0809 ,  A61B5/11 ,  A61B5/113 ,  A61B5/1135 ,  A61B5/4818

Abstract: Disordered breathing events may be classified as central, obstructive or a combination of central an obstructive in origin based on patient motion associated with respiratory effort. Central disordered breathing is associated with disrupted respiration with reduced respiratory effort. Obstructive disordered breathing is associated with disrupted respiration accompanied by respiratory effort. A disordered breathing classification system includes a disordered breathing detector and a respiratory effort motion sensor. Components of the disordered breathing classification system may be fully or partially implantable.

Abstract translation: 基于与呼吸努力相关的患者运动，无序呼吸事件可被分类为中枢性，阻塞性或中枢性阻塞性组合。 呼吸中枢紊乱与呼吸力下降相关联。 阻塞性无序呼吸与伴随呼吸功能的呼吸中断有关。 无序呼吸分类系统包括无序呼吸检测器和呼吸力运动传感器。 无序呼吸分类系统的组成部分可以完全或部分植入。

公开(公告)号：US20080114219A1

公开(公告)日：2008-05-15

申请号：US11554986

申请日：2006-10-31

Applicant: Yi Zhang ,  John D. Hatlestad ,  Gerrard M. Carlson ,  Yousufali Dalal ,  Marina V. Brockway ,  Kent Lee ,  Richard O. Kuenzler ,  Carlos Haro ,  Krzysztof Z. Siejko ,  Abhilash Patangay

Inventor： Yi Zhang ,  John D. Hatlestad ,  Gerrard M. Carlson ,  Yousufali Dalal ,  Marina V. Brockway ,  Kent Lee ,  Richard O. Kuenzler ,  Carlos Haro ,  Krzysztof Z. Siejko ,  Abhilash Patangay

IPC: A61B5/00

CPC classification number: A61M5/1723 ,  A61B5/02055 ,  A61B5/0215 ,  A61B5/024 ,  A61B5/02405 ,  A61B5/053 ,  A61B5/0816 ,  A61B5/1116 ,  A61B5/686 ,  A61B5/7275 ,  A61N1/36114 ,  A61N1/36135 ,  A61N1/3621 ,  A61N1/365 ,  A61N1/36585 ,  G06F19/00

Abstract: The health state of a subject is automatically evaluated or predicted using at least one implantable device. In varying examples, the health state is determined by sensing or receiving information about at least one physiological process having a circadian rhythm whose presence, absence, or baseline change is associated with impending disease, and comparing such rhythm to baseline circadian rhythm prediction criteria. Other chronobiological rhythms beside circadian may also be used. The baseline prediction criteria may be derived using one or more past physiological process observation of the subject or population of subjects in a non-disease health state. The prediction processing may be performed by the at least one implantable device or by an external device in communication with the implantable device. Systems and methods for invoking a therapy in response to the health state, such as to prevent or minimize the consequences of predicted impending heart failure, are also discussed.

Abstract translation: 使用至少一个可植入装置自动评价或预测受试者的健康状况。 在不同的实施例中，通过感测或接收关于至少一个具有昼夜节律的生理过程的信息来确定健康状况，所述生理过程的存在，不存在或基线变化与即将发生的疾病相关联，并将该节律与基线昼夜节律预测标准进行比较。 也可以使用昼夜节律以外的其他时间生理节律。 可以使用在非疾病健康状态下的受试者或受试者群体的一个或多个过去的生理过程观察来导出基线预测标准。 预测处理可以由至少一个可植入装置或与可植入装置通信的外部装置执行。 还讨论了响应于健康状态调用疗法的系统和方法，例如预防或最小化预期的即将到来的心力衰竭的后果。

公开(公告)号：US20080082001A1

公开(公告)日：2008-04-03

申请号：US11466925

申请日：2006-08-24

Applicant: John D. Hatlestad ,  Imad Libbus ,  Aaron Lewicke

Inventor： John D. Hatlestad ,  Imad Libbus ,  Aaron Lewicke

IPC: A61B5/02

CPC classification number: A61B5/1116 ,  A61B5/0031 ,  A61B5/021 ,  A61B5/02405 ,  A61B5/076 ,  A61B5/686 ,  A61B2562/0219 ,  A61N1/05

Abstract: In an embodiment, an implantable medical device includes a controller circuit, a posture sensing circuit, and a physiological sensing circuit. The controller circuit senses a change in a physiological signal as a result of a change in posture, and generates a response as a function of that change. In another embodiment, the controller circuit identifies a heart failure condition as a function of the change in the physiological signal.

Abstract translation: 在一个实施例中，可植入医疗装置包括控制器电路，姿势感测电路和生理感测电路。 控制器电路作为姿势变化的结果感测生理信号的变化，并产生作为该变化的函数的响应。 在另一个实施例中，控制器电路根据生理信号的变化来识别心力衰竭状况。

公开(公告)号：US5555464A

公开(公告)日：1996-09-10

申请号：US506987

申请日：1995-07-28

Applicant: John D. Hatlestad

Inventor： John D. Hatlestad

IPC: A01M7/00 ,  H04N5/33 ,  H04N9/097 ,  H04N9/07

CPC classification number: H04N5/332 ,  A01M7/0089 ,  H04N5/33 ,  H04N9/097

Abstract: A CCD camera is adapted for detecting red and near-infrared wavelengths by employing filters that are constructed to allow for the passage of only red light in certain areas and near-infrared light in other areas of the filter. The areas are designed to match the pixel geometry of the lens of a primary color CCD camera that has a predefined pattern of red, blue and green pixels. The match is such that the red bandpass filter areas overlay the red pixels, and the near-infrared bandpass filter areas match the blue and green pixel areas. The red, green and blue output lines of the CCD camera are supplied to a signal processor which uses the signals on these lines to provide combinations of red and near-infrared magnitude that are capable of detecting vegetation from a background. The camera is suitable for full color use again merely by removing the filter that provides R and NIR sensing without otherwise disabling or modifying the camera.

Abstract translation: CCD摄像机适用于通过使用滤波器来检测红色和近红外波长，滤光片被构造成允许仅在过滤器的其它区域中的特定区域中的红光和近红外光通过。 这些区域被设计成匹配具有预定义的红色，蓝色和绿色像素图案的原色CCD相机的透镜的像素几何形状。 该匹配使得红色带通滤波器区域覆盖红色像素，并且近红外带通滤波器区域与蓝色和绿色像素区域匹配。 CCD相机的红色，绿色和蓝色输出线被提供给使用这些线上的信号的信号处理器来提供能够从背景检测植被的红色和近红外幅度的组合。 相机仅适用于全彩色使用，只需通过移除提供R和NIR传感器的滤镜，无需其他方式禁用或修改相机。

公开(公告)号：US09393415B2

公开(公告)日：2016-07-19

申请号：US13309320

申请日：2011-12-01

Applicant: Shantha Arcot-Krishnamurthy ,  Yi Zhang ,  John D. Hatlestad

Inventor： Shantha Arcot-Krishnamurthy ,  Yi Zhang ,  John D. Hatlestad

IPC: A61B5/02 ,  A61N1/36 ,  A61B5/053 ,  A61N1/365

CPC classification number: A61N1/36053 ,  A61B5/0538 ,  A61N1/36117 ,  A61N1/36135 ,  A61N1/36521

Abstract: A device embodiment is configured to deliver vagal stimulation therapy (VST) to a vagus nerve of a patient. The device embodiment includes a neural stimulator, an implantable impedance sensor and an impedance analyzer. The neural stimulator is configured to deliver the VST to the vagus nerve in a cervical region of the patient. The implantable impedance sensor is configured to detect impedance changes in a cervical region of the patient caused by laryngeal vibrations. The impedance sensor is configured to generate sensed impedance values. The impedance analyzer is configured to analyze the sensed impedance values generated by the sensor. The analyzer is configured to detect laryngeal vibrations or cough from the sensed impedance values.

Abstract translation: 设备实施例被配置为将迷走神经刺激治疗（VST）递送到患者的迷走神经。 装置实施例包括神经刺激器，可植入阻抗传感器和阻抗分析器。 神经刺激器被配置成将VST输送到患者的颈部区域中的迷走神经。 可植入阻抗传感器被配置为检测由喉部振动引起的患者的颈部区域中的阻抗变化。 阻抗传感器被配置为产生感测的阻抗值。 阻抗分析器被配置为分析由传感器产生的感测阻抗值。 分析器被配置为检测来自感测的阻抗值的喉部振动或咳嗽。

公开(公告)号：US09066659B2

公开(公告)日：2015-06-30

申请号：US13437318

申请日：2012-04-02

Applicant: Pramodsingh Hirasingh Thakur ,  Abhilash Patangay ,  John D. Hatlestad ,  Kenneth C. Beck

Inventor： Pramodsingh Hirasingh Thakur ,  Abhilash Patangay ,  John D. Hatlestad ,  Kenneth C. Beck

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/11 ,  G06F19/00 ,  A61N1/365

CPC classification number: A61B5/0205 ,  A61B5/0031 ,  A61B5/02405 ,  A61B5/076 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/686 ,  A61B5/7246 ,  A61B5/7275 ,  A61B5/742 ,  A61B2560/0462 ,  A61B2562/0219 ,  A61N1/36535 ,  G06F19/34 ,  G16H20/40

Abstract: Patient posture information can be received, such as to indicate a change in patient posture by at least a threshold amount. A transient response signal indicative of a change in a physiological parameter can be received at multiple instances near a change in patient posture. Waveform morphology features can be extracted from a transient response signal and used to provide an indication of a cardiac status, such as a heart failure status.

Abstract translation: 可以接收患者姿势信息，例如指示患者姿势的变化至少阈值量。 可以在患者姿势变化附近的多个实例处接收表示生理参数变化的瞬时响应信号。 可以从瞬态响应信号中提取波形形态特征，并用于提供心脏状态的指示，例如心力衰竭状态。

公开(公告)号：US08905938B2

公开(公告)日：2014-12-09

申请号：US13479967

申请日：2012-05-24

Applicant: John D. Hatlestad ,  Marina Brockway ,  Yousufali Husaini Dalal ,  Loell Boyce Moon

Inventor： John D. Hatlestad ,  Marina Brockway ,  Yousufali Husaini Dalal ,  Loell Boyce Moon

IPC: A61B5/08 ,  A61N1/365 ,  A61B5/00 ,  A61B5/053 ,  A61N1/39 ,  A61N1/368

CPC classification number: A61B5/0535 ,  A61B5/0809 ,  A61B5/7207 ,  A61N1/36521 ,  A61N1/3684 ,  A61N1/3962

Abstract: Implantable medical devices and techniques are implemented that use bio-impedance to measure aspects of patient physiology. A signal separation method is performed at least in part in an implantable device. The method involves detecting a plurality of impedance signals using a plurality of implantable electrodes coupled to the implantable device. The method further involves separating one or more signals from the plurality of impedance signals using a signal separation technique, such as an algorithm-based separation technique.

Abstract translation: 实施了可植入的医疗设备和技术，其使用生物阻抗来测量患者生理学的方面。 信号分离方法至少部分地在可植入装置中进行。 该方法包括使用耦合到可植入装置的多个可植入电极来检测多个阻抗信号。 该方法还包括使用诸如基于算法的分离技术之类的信号分离技术来分离来自多个阻抗信号的一个或多个信号。