公开(公告)号：US11510987B2

公开(公告)日：2022-11-29

申请号：US16426184

申请日：2019-08-07

Applicant: Saitama University ,  QUARRYMEN & Co. Inc.

Inventor： Miho Suzuki ,  Ken Hatano ,  Shojiro Yoshida ,  Yasuhiro Yamashita

IPC: A61K47/42 ,  A61K9/107 ,  A61K38/17 ,  A61K38/22 ,  A61K39/395 ,  A61K47/24

Abstract: The present invention addresses the problem of providing an endocytosis enhancer comprising associates formed from a fluorescent protein. The fluorescent protein is preferably any one selected from the group consisting of a white fluorescent protein, a red fluorescent protein, a yellow fluorescent protein, a blue fluorescent protein and a green fluorescent protein. The endocytosis enhancer according to the present invention can enhance the cellular uptake of a drug, which is encapsulated in micelles each formed from a fluorescent-protein-supported carbosilane dendrimer, through endocytosis.

公开(公告)号：US20220271433A1

公开(公告)日：2022-08-25

申请号：US17741447

申请日：2022-05-11

Applicant: National University Corporation Saitama University ,  Murata Manufacturing Co., Ltd.

Inventor： Masataka OHIRA ,  Kaoru SUDO ,  Yoshinori TAGUCHI

IPC: H01Q9/04 ,  H01Q15/24 ,  H01Q1/22 ,  H01Q19/13

Abstract: An antenna module includes: a radiating element and a filter device including a plurality of resonators. The plurality of resonators include a first resonator and a second resonator, the second resonator being disposed at a final stage. The first resonator and the second resonator are each electrically coupled to the radiating element. A degree of a coupling of the resonator and the radiating element is weaker than a degree of a coupling of the resonator and the radiating element.

公开(公告)号：US10923354B2

公开(公告)日：2021-02-16

申请号：US16485937

申请日：2017-10-26

Applicant: Shin-Etsu Polymer Co., Ltd. ,  National University Corporation Saitama University

Inventor： Junichi Ikeno ,  Yohei Yamada ,  Hideki Suzuki

IPC: H01L21/04 ,  H01L21/02 ,  H01L21/302 ,  H01L21/67

Abstract: An etching method in which: molten sodium hydroxide in a prescribed temperature range is used as a molten alkali, whereby an Si surface of an etching surface of an SiC substrate, in which the substrate surface is configured from the Si surface and a C surface, is removed at a higher speed than is the C surface while an oxide film is formed on the etching surface in a high-temperature environment containing oxygen.

公开(公告)号：US20200243343A1

公开(公告)日：2020-07-30

申请号：US16486272

申请日：2017-10-26

Applicant: Shin-Etsu Polymer Co., Ltd. ,  National University Corporation Saitama University

Inventor： Junichi IKENO ,  Yohei YAMADA ,  Hideki SUZUKI

IPC: H01L21/306 ,  H01L21/02 ,  H01L21/311

Abstract: An etching method for etching a substrate using a molten alkali, wherein, while an oxide coating is formed on the surface of the substrate PL to be etched in a high-temperature oxygen-containing environment, the surface to be etched is isotropically etched to remove the oxide coating using a molten alkali AL brought into a prescribed high-temperature range.

公开(公告)号：US20190276735A1

公开(公告)日：2019-09-12

申请号：US16335344

申请日：2017-09-26

Applicant: National University Corporation SAITAMA UNIVERSITY

Inventor： Ken Hatano ,  Takahiko Matsushita ,  Daisuke Fujikawa ,  Koji Matsuoka

IPC: C09K11/06 ,  C08F2/44 ,  C08F230/08 ,  C08F212/36 ,  C08K5/14 ,  C08F212/08

Abstract: It is an object of the present invention to provide a fine fluorescent particle, which does not cause concentration quenching and has low ecotoxicity. Specifically, the present invention relates to a fine fluorescent particle containing an AIE-active compound, the particle consisting of a network polymer, wherein the fine fluorescent particle is characterized in that the AIE-active compound is, for example, a compound represented by the following formula (1): wherein E represents silicon or germanium; R1 and R2, which are the same or different, each represent a hydrocarbon group containing 1 to 6 carbon atoms, or a substituted or unsubstituted phenyl group; and R3, R4, R5 and R6, which are the same or different, each represent a substituted or unsubstituted phenyl group.

公开(公告)号：US09682126B2

公开(公告)日：2017-06-20

申请号：US14779730

申请日：2014-02-10

Applicant: ZERIA PHARMACEUTICAL CO., LTD. ,  SAITAMA UNIVERSITY

Inventor： Takafumi Sakai ,  Ichiro Sakata ,  Kayuri Kuroda ,  Makoto Yoshimura

IPC: A61K38/22 ,  A61K38/25 ,  A61K45/00 ,  A61K45/06

CPC classification number: A61K38/2214 ,  A61K9/0019 ,  A61K9/0053 ,  A61K38/22 ,  A61K38/25 ,  A61K45/06 ,  A61K2300/00

Abstract: To provide a therapeutic agent for gastrointestinal disorder such as diabetic gastroparesis. A postprandial gastrokinetic agent containing (A) ghrelin or a ghrelin agonist and (B) motilin or a motilin agonist as active ingredients, in which both the ingredients (A) and (B) are administered so as to act on the stomach after food intake.

公开(公告)号：US20240204412A1

公开(公告)日：2024-06-20

申请号：US18591003

申请日：2024-02-29

Applicant: National University Corporation Saitama University ,  Murata Manufacturing Co., Ltd.

Inventor： Masataka OHIRA ,  Kaoru SUDO ,  Yoshinori TAGUCHI

IPC: H01Q9/04 ,  H01P1/20 ,  H01Q1/24 ,  H01Q23/00

CPC classification number: H01Q9/0442 ,  H01Q1/243 ,  H01Q23/00 ,  H01P1/20

Abstract: An antenna module includes a dielectric substrate, a radiating element that is arranged in the dielectric substrate, ground electrodes that are arranged to be opposed to the radiating element, and a resonance circuit. The resonance circuit is arranged between the radiating element and the ground electrode and includes resonators. The radiating element and the resonance circuit constitute a filter device. The resonance circuit includes an input line that receives a radio frequency signal from an RFIC, a resonance portion that is coupled with the input line, and a resonance portion that is coupled with the input line and the radiating element. The ground electrode is arranged between the radiating element and the input line. The resonance portion functions as an extracted pole unit. The input line is arranged between the resonance portion and the resonance portion.

公开(公告)号：US20240200575A1

公开(公告)日：2024-06-20

申请号：US18590487

申请日：2024-02-28

Applicant: National University Corporation Saitama University

Inventor： Masaya TAKASAKI ,  Yuki NAKASUJI ,  Hayato SHIBATA ,  Takehiro ISHIDA

IPC: F04D29/66 ,  F04D29/38 ,  H02N2/10

CPC classification number: F04D29/661 ,  F04D29/384 ,  H02N2/103

Abstract: Provided is a novel technique that utilizes a vibrator and is applicable to various uses. This rotating apparatus comprises a vibrator having a vibrating surface that is perpendicular to a direction of vibration, and an opposing element that has an opposing surface facing the vibrating surface and rotates about the vibration direction of the vibrator. The vibrating surface and the opposing surface have parallel regions that face each other in parallel, and an impeller region formed in a three-dimensional manner on at least one of the surfaces.

公开(公告)号：US20230279371A1

公开(公告)日：2023-09-07

申请号：US18165191

申请日：2023-02-06

Applicant: SUMITOMO RUBBER INDUSTRIES, LTD. ,  TOHOKU UNIVERSITY ,  KANAZAWA UNIVERSITY ,  NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY

Inventor： Haruhiko YAMAGUCHI ,  Yukino INOUE ,  Seiji TAKAHASHI ,  Toru NAKAYAMA ,  Satoshi YAMASHITA ,  Yuzuru TOZAWA

IPC: C12N9/10 ,  C12P5/00 ,  C12N15/82 ,  B60C1/00

CPC classification number: C12N9/1085 ,  C12Y205/0102 ,  C12P5/007 ,  C12N15/8257 ,  B60C1/0041

Abstract: Provided are a mutant cis-prenyltransferase (CPT) family protein and a method for producing a polyisoprenoid, which enable the production of a high molecular weight polyisoprenoid. Included is a mutant cis-prenyltransferase (CPT) family protein obtained by mutating the amino acid sequence of a C-terminal region of a cis-prenyltransferase (CPT) family protein not found on rubber particles to be identical or similar to the amino acid sequence of a C-terminal region of a cis-prenyltransferase (CPT) family protein found on rubber particles.

公开(公告)号：US20230002933A1

公开(公告)日：2023-01-05

申请号：US17856207

申请日：2022-07-01

Applicant: Shin-Etsu Polymer Co., Ltd. ,  Shin-Etsu Chemical Co., Ltd. ,  National University Corporation Saitama University

Inventor： Junichi IKENO ,  Yohei YAMADA ,  Hideki SUZUKI ,  Rika MATSUO ,  Hitoshi NOGUCHI

IPC: C30B33/04 ,  B23K26/40 ,  C30B29/04 ,  C30B33/08 ,  C04B41/00 ,  C04B41/91

Abstract: A method of manufacturing a diamond substrate includes: a step of placing a laser condensing unit 190 configured to condense laser light B so as to face an upper surface 10a of a block 10 of single crystal diamond, a step of forming a modified layer 20, which includes a processing mark 21 of graphite and a crack 22b extending along a surface (111) around the processing mark 21, in a partial region of the upper surface 10a of the block 10 along the surface (111) of the single crystal diamond, along the surface (111) of the single crystal diamond at a predetermined depth from the upper surface 10a of the block 10 by radiating the laser light B on the upper surface 10a of the block 10 from the laser condensing unit 190 under predetermined conditions and condensing the laser light B inside the block 10, and moving the laser condensing unit 190 and the block 10 in a relative manner two-dimensionally, and a step of forming a cleavage plane 25 at the predetermined depth of the remaining region of the upper surface 10a of the block 10 by spontaneously propagating cleavage from the modified layer 20.