公开(公告)号：US11485964B2

公开(公告)日：2022-11-01

申请号：US16931967

申请日：2020-07-17

Applicant: Worcester Polytechnic Institute

Inventor： Amy Peterson ,  Marsha Rolle ,  Ivan Ding

IPC: C12N13/00 ,  C12M3/00 ,  C12M1/00 ,  C12M1/12 ,  C12N5/00

Abstract: Device, and methods of using or making the device, for engineering cells in vitro are disclosed. In some aspects, a cell culture device comprises at least one glass or polymer surface configured for incubating cells in a culture medium; a charged molecule electrostatically bound to the surface; and a polyelectrolyte multilayer (PEM) electrostatically bound to the charged molecule, the PEM comprising one or more bi-layers of oppositely charged polyelectrolytes, and the PEM having a sufficient thickness to permit release of the charged molecule into the culture medium in a controlled released manner.

公开(公告)号：US11436714B2

公开(公告)日：2022-09-06

申请号：US16999560

申请日：2020-08-21

Applicant: WORCESTER POLYTECHNIC INSTITUTE ,  UNIVERSITY OF VIRGINIA PATENT FOUNDATION

Inventor： Jacob Whitehill ,  Anand Ramakrishnan ,  Erin Ottmar ,  Jennifer LoCasale-Crouch

IPC: G06K9/62 ,  G06T7/00 ,  G10L25/63 ,  G10L25/30 ,  G10L25/57 ,  G06N3/08 ,  G06N3/04 ,  G09B19/00 ,  G06V20/40 ,  G06V40/16

Abstract: Embodiments of the innovation relate to an emotional quality estimation device comprising a controller having a memory and a processor, the controller configured to execute a training engine with labelled training data to train a neural network and generate a classroom analysis machine, the labelled training data including historical video data and an associated classroom quality score table; receive a classroom observation video from a classroom environment; execute the classroom analysis machine relative to the classroom observation video from the classroom environment to generate an emotional quality score relating to the emotional quality of the classroom environment; and output the emotional quality score for the classroom environment.

公开(公告)号：US20220236484A1

公开(公告)日：2022-07-28

申请号：US17584745

申请日：2022-01-26

Applicant: Worcester Polytechnic Institute

Inventor： Yuxiang Liu ,  Pratap Rao ,  Yundong Ren ,  Mucheng Li

IPC: G02B6/12 ,  G02B6/35 ,  G02B6/42 ,  G02B6/02

Abstract: A fiber optic sensing device includes an optical fiber having a polished end defining a flat sensory portion coated with a lossy-mode-resonance (LMR) coating. A reflective coating on an end face of the optical fiber facilitates propagation of a return signal. An optic circuit for identifies a wavelength attenuated by the LMR coating from the return signal reflected by the reflective coating based on a moisture presence at the sensory portion. Various gaseous parameters may be detected based on the coating on the sensory portion. An LMR coating of tin oxide (SnO2) is employed for moisture sensing.

公开(公告)号：US20220185688A1

公开(公告)日：2022-06-16

申请号：US17547557

申请日：2021-12-10

Applicant: Worcester Polytechnic Institute

Inventor： Himanshu Tanvar ,  Brajendra Mishra

IPC: C01F7/0653 ,  C01F7/066

Abstract: Bauxite residue recovery includes mixing a solution of hydrochloric acid (HCL) according to a predetermined concentration, and adding the HCL solution to a quantity of raw red mud recovered from industrial operations as waste material. The highly alkaline property of the bauxite residue, commonly known as red mud is at least partially neutralized from the HCL, and makes the resulting washed red mud more amenable to subsequent uses in various applications in fields such as construction, wastewater treatment, and metal recovery processes. The process recovers washed red mud from the red mud and HCL solution by filtering the raw red mud and HCL solution for generating a stream of leach liquor from the filtrate and the recovered washed red mud from the residue.

公开(公告)号：US20220115574A1

公开(公告)日：2022-04-14

申请号：US17500881

申请日：2021-10-13

Applicant: Worcester Polytechnic Institute

Inventor： Sathwik Bharadwaj Daralagodu Dattatreya Jois ,  Ashwin Ramasubramaniam ,  Lakshminarayanapuram Ramdas Ram-Mohan

IPC: H01L35/04 ,  H01L35/34

Abstract: A method of fabricating a two dimensional thermoelectric device includes forming dissimilar atomic layers having quantum electron transport properties, and forming a well-defined interface between the dissimilar atomic layers for effecting a thermoelectric transport by exploiting a gradient in the material parameters between the layers. The resulting device defines an inclusion matrix of the dissimilar atomic layers such that the inclusion layer is confined within a matrix formed by the other atomic layer.

公开(公告)号：US11266373B2

公开(公告)日：2022-03-08

申请号：US15488364

申请日：2017-04-14

Applicant: Worcester Polytechnic Institute ,  University of Massachusetts

Inventor： Dennis Giaya ,  Rebecca Stolarczyk ,  Yitzhak Mendelson ,  Arriyan Samandar Dowlatshahi ,  Raymond Dunn

IPC: A61B8/06 ,  A61B8/00 ,  A61B5/026 ,  G01S15/89 ,  A61B5/055 ,  G01S7/52 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/00 ,  A61B8/08 ,  A61B8/12 ,  A61B5/02 ,  G16H40/67 ,  G16Z99/00 ,  A61B5/024 ,  A61B5/022

Abstract: The present invention relates to devices and methods for measuring vascular deficiency using Doppler ultrasound detection. Embodiments can be used to monitor the condition of surgical tissue flaps or other conditions in which obstruction in the vascular system can impact patient health. The systems can include a Doppler ultrasound probe, a color probe, a temperature probe, and/or other suitable probes to measure blood volume and perfusion status of a tissue region. The systems and methods can be used to monitor flaps after flap transplant surgeries. The systems and methods can automatedly assess tissue condition and alert the patient or medical staff if the condition has fallen below a threshold indicating occlusion of a blood vessel. One or more additional sensors can be integrated into a probe to measure vascular conditions and a metric can be computed based on sensed data.

公开(公告)号：US20220023743A1

公开(公告)日：2022-01-27

申请号：US17499052

申请日：2021-10-12

Applicant: Worcester Polytechnic Institute

Inventor： Christopher A. Brown ,  Madison M. Healey ,  Matthew Newell ,  Kendra S. O'Malley ,  Connor H. O'Neill

IPC: A63C9/00

Abstract: An impact absorbing ski binding interface device includes an elongated top plate having a toe end and a heel end adapted to engage a boot toe and a boot heel, respectively, and a bottom plate adapted to engage a ski, thereby securing the device between the boot and ski. A plurality of constant force spring linkages between the top plate and the bottom plate include a constant force spring linkage between the toe end and the bottom plate, and a constant force spring linkage between the heel end and the bottom plate, such that each of the constant force spring linkages have an opposed pair of deformable members for exerting a counterforce to vertical displacement forces between the top plate and the bottom plate for load mitigation.

公开(公告)号：US20210255186A1

公开(公告)日：2021-08-19

申请号：US17231533

申请日：2021-04-15

Applicant: Worcester Polytechnic Institute ,  University of Louisville Research Foundation, Inc.

Inventor： Balaji Panchapakesan ,  Farhad Khosravi ,  Shesh N. Rai

IPC: G01N33/574 ,  G01N15/10 ,  G01N27/12

Abstract: The present disclosure provides micro-array devices for capturing cells in blood and methods of their use. In some aspects, a method for counting cells in a blood sample is provided, the method comprising applying a blood sample onto a CNT device; allowing cells in the blood sample to differentially settle on the CNT device, and identifying and counting cells of preselected type in the blood sample.

公开(公告)号：US11002737B2

公开(公告)日：2021-05-11

申请号：US15718692

申请日：2017-09-28

Applicant: Worcester Polytechnic Institute ,  University of Louisville Research Foundation, Inc.

Inventor： Balaji Panchapakesan ,  Farhad Khosravi ,  Shesh N. Rai

IPC: G01N33/574 ,  G01N15/10 ,  G01N27/12 ,  G01N15/00

Abstract: The present disclosure provides micro-array devices for capturing cells in blood and methods of their use. In some aspects, a method for counting cells in a blood sample is provided, the method comprising applying a blood sample onto a CNT device; allowing cells in the blood sample to differentially settle on the CNT device, and identifying and counting cells of preselected type in the blood sample.

公开(公告)号：US20210128103A1

公开(公告)日：2021-05-06

申请号：US17083776

申请日：2020-10-29

Applicant: Worcester Polytechnic Institute

Inventor： Haichong Zhang ,  Ryosuke Tsumura ,  Yichuan Tang

IPC: A61B8/08 ,  A61B8/12 ,  A61B8/00

Abstract: A Ring-Arrayed Forward-viewing (RAF) ultrasound imaging and administration device combines an ultrasonic (US) US imager including a plurality of single element transducers arranged in a circular frame to define a ring array, and an instrument posture tracking circuit coupled to the ring array for performing RF (radio frequency) data acquisition with the plurality of ring-arrayed transducers. A needle holster is concentrically disposed in the ring array and is adapted to receive and direct an insertion instrument such as a needle, probe or extraction tool along an axis defined by a center of the ring array directed by the concentric needle holster. The tracking circuit includes a processor having instructions for instrument posture tracking and US imaging.