公开(公告)号：US20240399684A1

公开(公告)日：2024-12-05

申请号：US18678833

申请日：2024-05-30

Applicant: Alcon Inc.

Inventor： Newton T. Samuel ,  Ya-Wen Chang ,  Richard Charles Breitkopf ,  Augustine Twum Kumi ,  Steve Yun Zhang ,  David Borja ,  Ethan Leveillee ,  Joseph Michael Lindacher

IPC: B29D11/00 ,  B29C35/08 ,  B29K105/24 ,  B29L11/00 ,  G02B1/04

Abstract: The invention provides a method for producing embedded diffractive contact lenses involving use of a mold set in two-curing steps. The mold set consists of three mold halves, one of which is used twice, the first time for molding a diffractive insert and the second time for an embedded contact lens with the molded diffractive insert embedded therein. The twice-used mold half has been treated with a corona plasma or a vacuum UV in a central circular area having a diameter equal to or smaller than the diameter of the insert to ensure that the molded insert consistently adheres to the twice-used mold half, even though the other mating insert mold half for molding the diffractive insert has a great tendency to bind strongly the molded insert due to the diffractive structure on its molding surface.

公开(公告)号：US12116442B2

公开(公告)日：2024-10-15

申请号：US17313459

申请日：2021-05-06

Applicant: Alcon Inc.

Inventor： Jing Cheng ,  Yang Zheng ,  Steve Yun Zhang ,  Lindsay Olson

IPC: C08F283/12 ,  C08J3/075

CPC classification number: C08F283/12 ,  C08J3/075 ,  C08J2383/10

Abstract: The invention provides a contact lens manufacturing method comprising a process for removing unprocessed molded silicone hydrogel contact lenses from mold halves in a relatively efficient and consistent manner. The method of the invention involves using a silicone fluid (or so-called silicone oil) as non-reactive diluent in SiHy lens formulation for making SiHy contact lenses. Resultant SiHy contact lenses cast-molded from such a SiHy lens formulation can have a significantly reduced adhesion force with the molding surfaces of a lens mold and consequently a higher efficiency and consistency in removing unprocessed molded SiHy contact lenses from mold halves can be achieved. This method of the invention can be easily implemented in a production environment for enhancing the production yield.

公开(公告)号：US12111443B2

公开(公告)日：2024-10-08

申请号：US17688041

申请日：2022-03-07

Applicant: Alcon Inc.

Inventor： Michelle Plavnik ,  Richard Charles Breitkopf ,  Steve Yun Zhang ,  Zahra Bassampour ,  Chandana Kolluru

IPC: G02B1/04 ,  B29D11/00 ,  B29K83/00 ,  B29K105/00 ,  C08G77/20 ,  C08L83/04 ,  G02C7/04 ,  G02C7/10

CPC classification number: G02B1/043 ,  B29D11/00057 ,  B29D11/00067 ,  B29D11/00134 ,  B29D11/00192 ,  C08G77/20 ,  C08L83/04 ,  G02C7/04 ,  G02C7/102 ,  G02C7/108 ,  B29K2083/00 ,  B29K2105/0061 ,  B29K2995/0018 ,  C08L2201/10 ,  C08L2203/02 ,  C08L2312/00 ,  G02B2207/109

Abstract: Described herein is a method for producing a contact lens comprising a central photochromic zone that has a diameter of about 13 mm or less and is concentric with the central axis of the contact lens. The method comprises: applying a first polymerizable fluid composition containing at least one photochromic compound on a central portion of the molding surface of a female mold half to form a circular layer; partially photocuring, in situ, the circular layer in the female mold half by using a visible light; dispensing a second polymerizable fluid composition over the partially-cured circular layer on the molding surface of the female mold half; and a step of thermally curing the second polymerizable fluid composition and the partially-cured circular layer immersed therein in the mold cavity formed between the molding surfaces of the female mold half and a male mold half.

公开(公告)号：US11927512B2

公开(公告)日：2024-03-12

申请号：US17087983

申请日：2020-11-03

Applicant: Alcon Inc.

Inventor： Yuan Chang ,  Ying Zheng ,  Junhao Ge ,  Steve Yun Zhang ,  Karen Belinda Sentell ,  Jinbo Dou

IPC: G01N1/30 ,  G01N1/04 ,  G01N21/77 ,  G02B1/04

CPC classification number: G01N1/30 ,  G01N1/04 ,  G01N21/77 ,  G02B1/043 ,  G01N2001/302 ,  G01N2021/7786

Abstract: The invention provides a method for imaging and thickness determination of coatings on coated contact lenses. The method comprises selectively staining a negatively-charged-groups-containing coating over the lens body of a coated contact lens by immersing the coated contact lens in an aqueous solution comprising a fluorescently-labeled polycationic polymer and having a pH of from about 6.5 to 8.0; orthogonally cutting the selectively-stained coated contact lens; and determining the thickness of the coating on the coated contact lens. In addition, the invention provides a method for selecting a candidate coating material comprising negatively charged groups for applying a coating with a desired thickness onto silicone hydrogel contact lenses and for optimizing a coating process for producing coated silicone hydrogel contact lenses with a desired thickness coating thereon.

公开(公告)号：US11926689B2

公开(公告)日：2024-03-12

申请号：US17870329

申请日：2022-07-21

Applicant: Alcon Inc.

Inventor： Jinyu Huang ,  Frank Chang ,  Steve Yun Zhang ,  Feng Jing

IPC: C08L101/14 ,  C08F290/06 ,  C08G77/16 ,  C08G77/20 ,  C08G77/392 ,  C08L83/04 ,  G02B1/04 ,  C08G77/12

CPC classification number: C08F290/068 ,  C08G77/16 ,  C08G77/20 ,  C08G77/392 ,  G02B1/043 ,  C08G77/12 ,  G02B1/043 ,  C08L83/04 ,  G02B1/043 ,  C08L101/14

Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.

公开(公告)号：US20240018309A1

公开(公告)日：2024-01-18

申请号：US18465610

申请日：2023-09-12

Applicant: Alcon Inc.

Inventor： Steve Yun Zhang ,  Daqing Wu ,  Junhao Ge ,  Richard Charles Breitkopf ,  Xinming Qian ,  Zach Munoz ,  Matthew D. Nelson ,  Augustine Twum Kumi ,  Weihong Lang ,  Ying Zheng ,  Feng Jing ,  Frank Chang

IPC: C08G77/442 ,  C08G77/20 ,  C08G77/388 ,  C08G77/392 ,  C08G77/14 ,  C08L83/10 ,  G02B1/04 ,  C08G77/12 ,  B29D11/00 ,  G02C7/04

CPC classification number: C08G77/442 ,  C08G77/20 ,  C08G77/388 ,  C08G77/392 ,  C08G77/14 ,  C08L83/10 ,  C08L2201/10 ,  C08G77/12 ,  B29D11/00134 ,  G02C7/04 ,  G02B2207/109 ,  C08G2210/00 ,  G02B1/043

Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.

公开(公告)号：US20230350100A1

公开(公告)日：2023-11-02

申请号：US18308189

申请日：2023-04-27

Applicant: Alcon Inc.

Inventor： Lisa Nicole Hutfluss ,  Jing Cheng ,  Feng Jing ,  Steve Yun Zhang ,  Michelle Plavnik

IPC: G02B1/04 ,  B29D11/00

CPC classification number: G02B1/043 ,  B29D11/00134 ,  B29D11/00192 ,  B29K2083/00

Abstract: The invention provides a method for making silicone hydrogel contact lenses in a relatively efficient and consistent manner from a lens formulation (i.e., a polymerizable composition) including a thermal initiator having a 10-hour half-life temperature (T10hλ) under a controlled thermal curing scheme. A method of the invention comprises a step of curing the lens formulation in an oven according to a thermal curing profile that comprises or consists essentially of increasing the oven's temperature from room temperature or a temperature that is at least about 5° C. lower than T10hλ to a temperature that is at least 30° C. higher than T10hλ at a selected rate (e.g., from about 1° C./minute to about 10° C./minute). Under such a controlled thermal curing scheme, the lens diameter of the fully-hydrated silicone hydrogel contact lenses obtained according to a method of the invention does not vary significantly with the positions of the molds in the oven.

公开(公告)号：US20230166467A1

公开(公告)日：2023-06-01

申请号：US18070189

申请日：2022-11-28

Applicant: Alcon Inc.

Inventor： Yang Zheng ,  Cornelius Daniel Niculas ,  Yuan Chang ,  Junhao Ge ,  Steve Yun Zhang ,  Justin Joel Aguayo ,  David Andrew Icenogle ,  Muhammad Waqas Asif ,  Daryl Reece

IPC: B29D11/00 ,  G02C7/04 ,  G02B1/04

CPC classification number: B29D11/00519 ,  B29D11/00038 ,  G02B1/043 ,  G02C7/04 ,  B29K2083/00

Abstract: Systems, devices, and methods are disclosed for fabricating a hybrid contact lens product having a lens insert embedded at a precisely controlled location within a lens body. A mold engagement and support base engages and retains a lens forming mold in a substantially fixed position. An insert placement and positioning device includes an insert pickup head with a contact face configured for releasable engagement of the lens insert and at least one suction opening in the contact face for applying suction to engage the insert on the contact face. A positioning housing interacts with the mold and/or the support base to provide precise locational positioning of the lens insert within the mold. A lens body forming material is delivered to the mold to encapsulate the lens insert.

公开(公告)号：US20230117502A1

公开(公告)日：2023-04-20

申请号：US18047312

申请日：2022-10-18

Applicant: Alcon Inc.

Inventor： Michelle Plavnik ,  Junhao Ge ,  Steve Yun Zhang ,  Ethan Leveillee ,  Yang Zheng ,  Yuan Chang

IPC: B29D11/00

Abstract: A dosing system and method for delivery of contact lens formulation(s) to a contact lens forming mold. The system includes a carrier portion configured for holding a contact lens mold, and an alignment mandrel configured for retaining a lens formulation delivery device. The lens formulation delivery device is retained in a specified position relative to the contact lens mold for precise location of delivery of the lens formulation within the contact lens mold. A first lens formulation can be dosed to a center location in the mold, and a different second lens formulation can be dosed to a ring-shaped pattern around the center location, to form a contact lens having different center and edge characteristics.

公开(公告)号：US11629255B2

公开(公告)日：2023-04-18

申请号：US17205212

申请日：2021-03-18

Applicant: Alcon Inc.

Inventor： Zahra Bassampour ,  Jing Cheng ,  Steve Yun Zhang

IPC: C08L83/06 ,  C08F220/12 ,  C08G77/442 ,  G02B1/04

Abstract: The invention is generally related to an embedded silicone hydrogel contact lens comprising a silicone hydrogel material and a hydrophobic insert. The silicone hydrogel material comprises repeating units of at least one first polysiloxane vinylic crosslinker comprising hydrophilized siloxane units each having one methyl substituent and one organic radical including at least one H-bond donor (e.g., hydroxyl groups), wherein the content of said at least one H-bond donor is at least 0.8 meq/g relative to the molecular weight of said at least one first polysiloxane vinylic crosslinker. The hydrophobic insert is composed of a crosslinked polymeric material comprising at least 40% by mole of acrylic repeating units and at least 6% by mole of repeating units of at least one vinylic crosslinking agent. The embedded silicone hydrogel is not susceptible to delamination.