公开(公告)号：US20190337690A1

公开(公告)日：2019-11-07

申请号：US16510664

申请日：2019-07-12

Applicant: ILLUMINA, INC.

Inventor： Paul Crivelli ,  Gary Watts

IPC: B65D51/00 ,  B01L3/00 ,  B05C5/02

Abstract: A method is provided comprising loading shells into shell retention chambers of a shell management module, the shells including corresponding reservoirs configured to hold individual quantities of liquid, the shell retention chambers arranged in a predetermined pattern on a platform of the shell management module. The method further comprises orienting discharge ends of the shells along an actuation direction within the shell retention chambers, and covering the discharge ends with closure lids to seal bottoms of the corresponding reservoirs.

公开(公告)号：US10377538B2

公开(公告)日：2019-08-13

申请号：US15364462

申请日：2016-11-30

Applicant: Illumina, Inc.

Inventor： Paul Crivelli ,  Gary Watts

IPC: B65D51/00 ,  B05C5/02 ,  B01L3/00

Abstract: A liquid storage and delivery mechanism and method of use are provided. The mechanism comprises shells that include corresponding reservoirs to hold individual quantities of liquid. The shells include filling ends and discharge ends. The filling ends include fill ports that open to the reservoirs in order to receive the corresponding quantity of liquid. The discharge ends are covered with closure lids to seal bottoms of the corresponding reservoirs. A shell management module is provided comprising a cover and a platform. The platform includes shell retention chambers to receive corresponding shells. The shell retention chambers are arranged in a predetermined pattern on the platform. The shell retention chambers are to orient shells with the fill ports exposed from the platform. The cover is mounted onto the platform to close the fill ports. The shells are to move individually, along the shell retention chambers, between non-actuated and actuated positions.

公开(公告)号：US20190240660A1

公开(公告)日：2019-08-08

申请号：US16264146

申请日：2019-01-31

Applicant: Illumina, Inc.

Inventor： Darren Segale ,  Hai Tran ,  Paul Crivelli

IPC: B01L3/00

Abstract: A circuit with electrical interconnect for external electronic connection and sensor(s) on a die are combined with a laminated manifold to deliver a liquid reagent over an active surface of the sensor(s). The laminated manifold includes fluidic channel(s), an interface between the die and the fluidic channel(s) being sealed. Also disclosed is a method, the method including assembling a laminated manifold including fluidic channel(s), attaching sensor(s) on a die to a circuit, the circuit including an electrical interconnect, and attaching a planarization layer to the circuit, the planarization layer including a cut out for the die. The method further includes placing sealing adhesive at sides of the die, attaching the laminated manifold to the circuit, and sealing an interface between the die and fluidic channel(s).

公开(公告)号：US20170152081A1

公开(公告)日：2017-06-01

申请号：US15364462

申请日：2016-11-30

Applicant: Illumina, Inc.

Inventor： Paul Crivelli ,  Gary Watts

IPC: B65D47/18 ,  B05C11/10 ,  B65D51/00 ,  B05C5/02

CPC classification number: B65D51/002 ,  B01L3/5025 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/502792 ,  B01L3/527 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/0668 ,  B01L2200/0684 ,  B01L2200/142 ,  B01L2300/023 ,  B01L2300/043 ,  B01L2300/044 ,  B01L2300/045 ,  B01L2300/0672 ,  B01L2300/0809 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/161 ,  B01L2300/18 ,  B01L2400/0478 ,  B01L2400/0655 ,  B05C5/02

Abstract: A liquid storage and delivery mechanism and method of use are provided. The mechanism comprises shells that include corresponding reservoirs to hold individual quantities of liquid. The shells include filling ends and discharge ends. The filling ends include fill ports that open to the reservoirs in order to receive the corresponding quantity of liquid. The discharge ends are covered with closure lids to seal bottoms of the corresponding reservoirs. A shell management module is provided comprising a cover and a platform. The platform includes shell retention chambers to receive corresponding shells. The shell retention chambers are arranged in a predetermined pattern on the platform. The shell retention chambers are to orient shells with the fill ports exposed from the platform. The cover is mounted onto the platform to close the fill ports. The shells are to move individually, along the shell retention chambers, between non-actuated and actuated positions.