Closed loop cardiac resynchronization therapy using cardiac activation sequence information
    31.
    发明申请
    Closed loop cardiac resynchronization therapy using cardiac activation sequence information 有权
    闭环心脏再同步治疗使用心脏激活序列信息

    公开(公告)号:US20060253162A1

    公开(公告)日:2006-11-09

    申请号:US11125068

    申请日:2005-05-09

    CPC classification number: A61N1/3712 A61N1/3627 A61N1/365 G06F19/00

    Abstract: Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend closed-loop cardiac resynchronization therapy using cardiac activation sequence information. Devices and methods involve sensing a plurality of composite cardiac signals using a plurality of electrodes, the electrodes configured for implantation in a patient. A source separation is performed using the sensed plurality of composite cardiac signals, producing one or more cardiac signal vectors associated with all or a portion of one or more cardiac activation sequences. A cardiac resynchronization therapy is adjusted using one or both of the one or more cardiac signal vectors and the signals associated with the one or more cardiac signal vectors. In further embodiments, the cardiac resynchronization therapy may be initiated, terminated, or one or more parameters of the resynchronization therapy may be altered.

    Abstract translation: 提供一种或多种监测,诊断,除颤和起搏的心脏监测和/或刺激方法和系统。 心脏信号分离用于使用心脏激活序列信息来检测,监测,跟踪和/或趋势闭环心脏再同步治疗。 设备和方法包括使用多个电极感测多个复合心脏信号,所述电极被配置用于植入患者体内。 使用所感测的多个复合心脏信号进行源分离,产生与一个或多个心脏激活序列的全部或一部分相关联的一个或多个心脏信号载体。 使用一个或多个心脏信号向量和与一个或多个心脏信号载体相关联的信号中的一个或两个来调整心脏再同步治疗。 在另外的实施方案中,心脏再同步治疗可以被启动,终止,或者可以改变再同步治疗的一个或多个参数。

    Method and apparatus for adjustable AVD programming using a table
    35.
    发明申请
    Method and apparatus for adjustable AVD programming using a table 有权
    使用表格调整AVD编程的方法和装置

    公开(公告)号:US20050131480A1

    公开(公告)日:2005-06-16

    申请号:US10735267

    申请日:2003-12-12

    CPC classification number: A61N1/3627 A61N1/365 A61N1/3682

    Abstract: A pacing system provides for optimal hemodynamic cardiac function for parameters such as ventricular synchrony or contractility (peak left ventricle pressure change during systole or LV+dp/dt), or stroke volume (aortic pulse pressure) using system for calculating atrio-ventricular delays for optimal timing of a ventricular pacing pulse. The system deriving the proper timing using electrical or mechanical events having a predictable relationship with an optimal ventricular pacing timing signal. A look-up table relating the timing of such electrical or mechanical events to atrioventricular delay time intervals is provided for programming the pacing system.

    Abstract translation: 起搏系统提供用于参数的最佳血液动力学心脏功能,例如心室同步或收缩性(收缩期左心室压力峰值或LV + dp / dt)或行程体积(主动脉脉压),用于计算房室延迟的系统 心室起搏脉冲的最佳时机。 该系统使用与最佳心室起搏定时信号具有可预测关系的电或机械事件导出适当的定时。 提供了将这种电气或机械事件的时间与房室延迟时间间隔相关联的查找表用于对起搏系统进行编程。

    Apparatus and method for ventricular pacing triggered by detection of early ventricular excitation
    37.
    发明授权
    Apparatus and method for ventricular pacing triggered by detection of early ventricular excitation 有权
    通过检测早期心室激发触发心室起搏的装置和方法

    公开(公告)号:US06768923B2

    公开(公告)日:2004-07-27

    申请号:US10004695

    申请日:2001-12-05

    CPC classification number: A61N1/365

    Abstract: A pacing apparatus and method for providing optimum timing for ventricular pacing without referencing atrial activities. The pacing apparatus includes a processor, at least one sensor and a pulse generator. The pacing method includes the sensing of ventricular depolarization and the identification of an early electrical event, such as a depolarization of the HIS bundle or an onset of a ventricular depolarization (Q*). The system derives the proper timing using this early electrical event which provides a predictable relationship with an optimal ventricular pacing signal.

    Abstract translation: 一种用于在不参考心房活动的情况下为心室起搏提供最佳时机的起搏装置和方法。 起搏装置包括处理器,至少一个传感器和脉冲发生器。 起搏方法包括感测心室去极化和识别早期电气事件,例如HIS束的去极化或心室去极化(Q *)的发作。 该系统使用这种早期电气事件导出适当的时间,其提供与最佳心室起搏信号的可预测关系。

    Ventricular conduction delay trending system and method
    38.
    发明授权
    Ventricular conduction delay trending system and method 有权
    心室传导延迟趋势系统及方法

    公开(公告)号:US06763267B2

    公开(公告)日:2004-07-13

    申请号:US10054427

    申请日:2002-01-22

    Applicant: Jiang Ding

    Inventor: Jiang Ding

    CPC classification number: A61N1/3702 A61N1/3627 A61N1/365

    Abstract: A method and system for ascertaining the condition of the heart's conduction system in a patient treated for congestive heart failure with pacing therapy. In accordance with the invention, changes in ventricular activation patterns are monitored over time in order to detect changes in the heart's conduction system that may occur due to physiological regeneration of conduction pathways. The activation patterns are reflected by electrogram signals detected from different ventricular locations. By measuring the difference in conduction times of an excitation impulse traveling from the AV node to the different ventricular locations, a parameter representative of the heart's conduction system is obtained that may be used to adjust the pacing therapy in accordance therewith.

    Abstract translation: 一种确定心脏传导系统状态的方法和系统,用于采用起搏治疗充血性心力衰竭治疗的患者。 根据本发明,随着时间的推移监测心室激活模式的变化,以便检测由于传导途径的生理再生而可能发生的心脏传导系统的变化。 激活模式由从不同心室位置检测到的电描记图信号反映。 通过测量从AV节点行进到不同心室位置的激励脉冲的传导时间的差异,可以获得代表心脏传导系统的参数,其可用于根据其调节起搏疗法。

    Method and apparatus for determining the coronary sinus vein branch accessed by a coronary sinus lead
    39.
    发明授权
    Method and apparatus for determining the coronary sinus vein branch accessed by a coronary sinus lead 有权
    用于确定冠状静脉窦导管接近的冠状静脉窦静脉分支的方法和装置

    公开(公告)号:US06705999B2

    公开(公告)日:2004-03-16

    申请号:US09822638

    申请日:2001-03-30

    Abstract: Systems and methods for determining the coronary sinus vein branch location of a left ventricle electrode are disclosed. The systems and methods involve detecting the occurrence of electrical events within the patient's heart including sensing one or more of the electrical events with the electrode and then analyzing the electrical events to determine the electrode's position. The determination of electrode position may be used to automatically adjust operating parameters of a VRT device. Furthermore, the determination of electrode position may be made in real-time during installation of the electrode and a visual indication of the electrode position may be provided on a display screen.

    Abstract translation: 公开了用于确定左心室电极的冠状静脉窦静脉分支位置的系统和方法。 系统和方法涉及检测患者心脏内的电事件的发生,包括用电极感测一个或多个电事件,然后分析电气事件以确定电极的位置。 电极位置的确定可用于自动调整VRT器件的工作参数。 此外,可以在电极的安装期间实时地确定电极位置,并且可以在显示屏上提供电极位置的视觉指示。

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