公开(公告)号：US20160279282A1

公开(公告)日：2016-09-29

申请号：US15081648

申请日：2016-03-25

Applicant: MicroVention, Inc.

Inventor： Gregory M. Cruise ,  Steve Plotkin ,  Xinping Wu

IPC: A61L24/06 ,  A61L24/00 ,  C08F222/38

CPC classification number: A61L24/06 ,  A61L24/001 ,  A61L2430/36 ,  C08F222/385 ,  C08L33/08 ,  C08L33/10 ,  C08L33/26

Abstract: Embolic particles are described comprising a treated polymer particle. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer. The treated polymer particles can have a first diameter that is smaller than a second diameter, wherein the second diameter is achieved when the treated polymer particle is subjected to a physiological condition. Methods of making and using these polymer particles are also described.

Abstract translation: 描述包含经处理的聚合物颗粒的栓塞颗粒。 颗粒是包含至少一种聚醚大分子单体和合适单体的预聚物溶液的反应产物。 经处理的聚合物颗粒可以具有小于第二直径的第一直径，其中当经处理的聚合物颗粒经受生理条件时，实现第二直径。 还描述了制备和使用这些聚合物颗粒的方法。