Abstract:
A method of imaging a site of interest in a body using an ultrasound probe comprising a plurality of ultrasound transducer elements comprises obtaining an ultrasound image of a pass zone between the ultrasound probe and the site of interest. The image includes the site of interest and a plurality of tissue regions in a pass zone between the site of interest and the ultrasound probe. Boundaries of a selected tissue region in the pass zone are determined from the image. Focusing delay times are then computed for each ultrasound transducer element based in part on the speed of sound in the selected tissue region other than an average speed of sound in body tissue, and the boundaries of the selected tissue region. Preferably, a speed about the speed of sound in the selected tissue region is used and more preferably the speed of sound in the selected tissue region is used. Refraction may be considered, as well. Ultrasound imaging of the site of interest is then conducted employing the computed delay times. Fat and bone tissue regions are typically selected if present. Other tissue regions may be selected, as well. The boundaries of the tissue region or regions may be determined by segmentation. Tissue inhomogeneity is thereby compensated for, improving image contrast resolution. Ultrasound imaging systems and software are also disclosed. A new ultrasound probe comprising high and low frequency transducer elements is also disclosed.
Abstract:
Various approaches to generating and maintaining an ultrasound focus at a target region include configuring a controller to cause transmission of treatment ultrasound pulses from a transducer having multiple transducer elements; cause the transducer to transmit focusing ultrasound pulses to the target region and generate an acoustic reflector therein; measure reflections of the focusing ultrasound pulses from the acoustic reflector; based at least in part on the measured reflections, adjust a parameter value associated with one or more transducer elements so as to maintain and/or improve the ultrasound focus at the target region.
Abstract:
Skull inhomogeneity may be quantified in accordance with the skull density measured in skull images acquired using a conventional imager; the quantified inhomogeneity may then be used to determine whether the patient is suitable for ultrasound treatment and/or determine parameters associated with the ultrasound transducer for optimizing transskull ultrasound treatment.
Abstract:
Disclosed are thermal treatment methods that involve monitoring and/or actively adjusting the temperature of targeted and/or non-targeted tissues.
Abstract:
Disclosed are systems and methods for focusing ultrasound transducers that include multiple separate, independently movable transducer segments.
Abstract:
Skull inhomogeneity may be quantified in accordance with the skull density measured in skull images acquired using a conventional imager; the quantified inhomogeneity may then be used to determine whether the patient is suitable for ultrasound treatment and/or determine parameters associated with the ultrasound transducer for optimizing transskull ultrasound treatment.
Abstract:
A focused ultrasound system includes an ultrasound transducer device forming an opening, and having a plurality of transducer elements positioned at least partially around the opening. A focused ultrasound system includes a structure having a first end for allowing an object to be inserted and a second end for allowing the object to exit, and a plurality of transducer elements coupled to the structure, the transducer elements located relative to each other in a formation that at least partially define an opening, wherein the transducer elements are configured to emit acoustic energy that converges at a focal zone.
Abstract:
A thermal treatment system including a heat applying element for generating thermal doses for ablating a target mass in a patient, a controller for controlling thermal dose properties of the heat applying element, an imager for providing preliminary images of the target mass and thermal images during the treatment, and a planner for automatically constructing a treatment plan, comprising a series of treatment sites that are each represented by a set of thermal dose properties. The planner automatically constructs the treatment plan based on input information including one or more of a volume of the target mass, a distance from a skin surface of the patient to the target mass, a set of default thermal dose prediction properties, a set of user specified thermal dose prediction properties, physical properties of the heat applying elements, and images provided by the imager. The default thermal dose prediction properties are preferably based on a type of clinical application and include at least one of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site, cooling time between thermal doses, and electrical properties for the heat applying element. The user specified thermal dose prediction properties preferably include at least one or more of overrides for any default thermal dose prediction properties, treatment site grid density; and thermal dose prediction properties not specified as default thermal dose prediction properties from the group comprised of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site cooling time between thermal doses, and electrical properties for the heat applying element.
Abstract:
Systems and methods for heating a surface substantially uniformly are provided. In various embodiments, the uniform heating is achieved by moving an ultrasound beam across the surface and/or by sequentially irradiating individual meshes of a mesh grid defined over the surface.
Abstract:
Disclosed are thermal treatment methods that involve monitoring and/or actively adjusting the temperature of targeted and/or non-targeted tissues.