公开(公告)号：US4871484A

公开(公告)日：1989-10-03

申请号：US50993

申请日：1987-05-15

Applicant: Helmut Fiege ,  Manfred Jautelat ,  Dieter Arlt

Inventor： Helmut Fiege ,  Manfred Jautelat ,  Dieter Arlt

IPC: C07C53/50 ,  C07C51/00 ,  C07C51/58 ,  C07C51/60 ,  C07C51/62 ,  C07C67/00

CPC classification number: C07C51/58

Abstract: A process for the preparation of a 2,2-bis-chloro-methyl-alkanecarboxylic acid of the formula ##STR1## in which R is hydrogen, alkyl, cycloalkyl or optionally substituted phenyl,which comprises reacting an oxetane-3-carboxylic acid of the formula ##STR2## or a salt thereof, with an inorganic acid chloride at a temperature between 20.degree. C. and the boiling point of the reaction mixture. The products are known intermediates for fungicides and herbicides.

Abstract translation: 一种制备式“IMAGE”的2,2-双氯 - 甲基 - 链烷羧酸的方法，其中R是氢，烷基，环烷基或任选取代的苯基，其中包括使氧杂环丁烷-3-羧酸 式中的“IMAGE”或其盐与无机酰氯在20℃和反应混合物的沸点之间。 该产品是用于杀真菌剂和除草剂的已知中间体。

公开(公告)号：US4824975A

公开(公告)日：1989-04-25

申请号：US49749

申请日：1987-05-13

Applicant: Helmut Fiege ,  Manfred Jautelat ,  Dieter Arlt

Inventor： Helmut Fiege ,  Manfred Jautelat ,  Dieter Arlt

IPC: C07B61/00 ,  B01J23/00 ,  B01J23/42 ,  B01J23/44 ,  C07C53/50 ,  C07D305/08

CPC classification number: C07C53/50 ,  C07D305/08

Abstract: A process for the preparation of an oxetane-3-carboxylic acid of the formula ##STR1## in which R represents hydrogen, alkyl, cycloalkyl or optionally substitute phenyl, comprising reacting a 3-hydroxymethyl-oxetane of the formula ##STR2## with oxygen in an aqueous alkaline medium at a temperature between about 0.degree. C. and the boiling point of the reaction mixture on a palladium and/or platinum catalyst. The product is an intermediate for known fungicides and herbicides.

Abstract translation: 制备式“IMAGE”的氧杂环丁烷-3-羧酸的方法，其中R表示氢，烷基，环烷基或任选取代的苯基，包括使式“IMAGE”的3-羟甲基 - 氧杂环丁烷与氧反应 在约0℃的温度和钯和/或铂催化剂上的反应混合物的沸点之间的碱性水溶液。 该产品是已知杀真菌剂和除草剂的中间体。

公开(公告)号：US4366325A

公开(公告)日：1982-12-28

申请号：US195157

申请日：1980-10-08

Applicant: Karlfried Wedemeyer ,  Helmut Fiege

Inventor： Karlfried Wedemeyer ,  Helmut Fiege

IPC: B01J23/00 ,  B01J23/62 ,  B01J23/644 ,  B01J27/057 ,  C07B61/00 ,  C07C45/00 ,  C07C45/38 ,  C07C47/575 ,  C07C51/235 ,  C07C67/00

CPC classification number: C07C45/38 ,  B01J23/628 ,  B01J23/6447 ,  B01J27/0576 ,  C07C47/575 ,  C07C51/235

Abstract: In a process for the preparation of 3-phenoxy-benzaldehyde by oxidation of 3-phenoxy-benzyl alcohol of the formula ##STR1## in which m represents a number from 1 to 4,n represents a number from 1 to 5 andR.sup.1 and R.sup.2 are identical or different and denote hydrogen, halogen, alkyl, cycloalkyl, aralkyl, alkoxy, cycloalkoxy, aryloxy or perfluoroalkyl,with an oxygen containing gas in aqueous alkali at a temperature from the solidification point to the boiling point of the reaction mixture in the presence of a platinum metal catalyst and in the presence of lead and/or bismuth and/or tellurium and/or a compound of said lead, bismuth or tellurium.

Abstract translation: 在通过氧化式“IMAGE”的3-苯氧基 - 苄醇制备3-苯氧基 - 苯甲醛的方法中，其中m表示1至4的数，n表示1至5的数，R1和R2 在相对于反应混合物的固化点至沸点的温度下，在碱存在下，与含氧气体一起表示氢，卤素，烷基，环烷基，芳烷基，烷氧基，环烷氧基，芳氧基或全氟烷基 的铂金属催化剂，并且在铅和/或铋和/或碲和/或所述铅，铋或碲的化合物存在下进行。

公开(公告)号：US4358616A

公开(公告)日：1982-11-09

申请号：US211987

申请日：1980-12-01

Applicant: Karlfried Wedemeyer ,  Helmut Fiege

Inventor： Karlfried Wedemeyer ,  Helmut Fiege

IPC: C07C323/16 ,  C07C20060101 ,  C07C67/00 ,  C07C313/00 ,  C07C148/00

CPC classification number: C07C323/00

Abstract: The present invention provides a process for the preparation of an alkylthiomethylphenol or arylthiomethylphenol of the general formula ##STR1## in which m, n, R and R.sup.1 have the meaning mentioned in the specification, in which a hydroxymethylphenol of the general formula ##STR2## is reacted with a mercaptan or thiophenol at a temperature of from 20.degree. to 200.degree. C., if appropriate in the presence of a diluent.

Abstract translation: 本发明提供了制备通式为“IMAGE”的烷基硫代甲基苯酚或芳基硫代甲基苯酚的方法，其中m，n，R和R 1具有说明书中提及的含义，其中通式“IMAGE”的羟甲基苯酚是 如果合适，在稀释剂存在下，在20℃至200℃的温度下与硫醇或苯硫酚反应。

公开(公告)号：US4245126A

公开(公告)日：1981-01-13

申请号：US71427

申请日：1979-08-30

Applicant: Helmut Fiege ,  Karlfried Wedemeyer ,  Kurt Bauer ,  Reiner Molleken

Inventor： Helmut Fiege ,  Karlfried Wedemeyer ,  Kurt Bauer ,  Reiner Molleken

IPC: B01J31/00 ,  B01J31/02 ,  C07B61/00 ,  C07C27/00 ,  C07C37/11 ,  C07C37/20 ,  C07C39/11 ,  C07C67/00

CPC classification number: C07C37/115 ,  Y02P20/52

Abstract: Mixtures of 2- and 4-hydroxybenzyl alcohol with high contents of 4-hydroxybenzyl alcohol are obtained by a process comprising reacting phenol with paraformaldehyde in the presence of a compound which exhibits two or more tertiary nitrogen atoms per molecule and a pK.sub.a value of .gtoreq.6.5 (measured at 20.degree. C. in water).

Abstract translation: 通过包括在每分子表现出两个或更多个叔氮原子的化合物和pKa值>的化合物的存在下使苯酚与多聚甲醛反应的方法获得具有高含量的4-羟基苄醇的2-和4-羟基苄醇的混合物， = 6.5（在20℃下在水中测量）。

公开(公告)号：US4150243A

公开(公告)日：1979-04-17

申请号：US744211

申请日：1976-11-22

Applicant: Dieter W. Bruck ,  Helmut Fiege ,  Johann Renner ,  Feliks Bitners ,  Josef Haydn ,  Karlfried Wedemeyer

Inventor： Dieter W. Bruck ,  Helmut Fiege ,  Johann Renner ,  Feliks Bitners ,  Josef Haydn ,  Karlfried Wedemeyer

IPC: C07C27/00 ,  C07C37/50 ,  C07C39/07 ,  C07C67/00 ,  C07C39/04

CPC classification number: C07C37/50

Abstract: A process for the tertiary dealkylation of a tertiary alkyl containing m- and/or p-cresol wherein a tertiary alkyl containing m- and/or p-cresol is continously introduced into a reaction vessel with a small amount of sulfuric acid or an quivalent amount of a sulfonic acid and the reaction vessel contains a high concentration of m- and/or p-cresol or a high boiling phenol which under the prevailing reaction conditions is not substantially vaporized from the reaction mixture. The reaction mixture is maintained at a temperature of no greater than 230.degree. C. The reaction products are withdrawn continuously from the reactor (and separated into its components) and at the same time a small amount of the reaction mixture being withdrawn intermittently or continously from the reactor.

Abstract translation: 含有m-和/或对甲酚的叔烷基叔烷基化的方法，其中将含有间 - 和/或对 - 甲酚的叔烷基连续地引入具有少量硫酸或一定量的硫酸的反应容器中 的磺酸，并且反应容器含有高浓度的m-和/或对甲酚或高沸点苯酚，其在主要反应条件下基本上不从反应混合物中汽化。 将反应混合物保持在不高于230℃的温度。将反应产物从反应器中连续取出（并分离成其组分），同时将少量的反应混合物间歇地或连续地从 反应堆。

公开(公告)号：US4113975A

公开(公告)日：1978-09-12

申请号：US757422

申请日：1977-01-06

Applicant: Helmut Fiege ,  Josef Haydn ,  Johann Renner ,  Karlfried Wedemeyer

Inventor： Helmut Fiege ,  Josef Haydn ,  Johann Renner ,  Karlfried Wedemeyer

IPC: C07C37/68 ,  C07C27/00 ,  C07C37/72 ,  C07C37/86 ,  C07C39/06 ,  C07C67/00 ,  C07C37/28

CPC classification number: C07C37/72

Abstract: A process for the removal of acids and potential acid-forming agents from a composition containing such acids and potential acid-forming agents and an alkylphenol which composition is obtained by reacting phenols with alkenes in the presence of sulfuric acid or a sulfonic acid, and for treating the effluent thereby obtained, the process being characterized by the steps of:(a) extracting a major amount of the acid constituents from the alkylphenol mixture by means of water;(b) treating the alkylphenol mixture with a dilute aqueous alkali solution in an amount such that the alkali is insufficient to neutralize all the acid originally present in the alkylphenol mixture,(c) separating the alkylphenol mixture from the aqueous alkali solution;(d) combining the aqueous phases obtained from steps (a) and (b);(e) heating the combined aqueous phases to a temperature of 100.degree. to 200.degree. C,(f) separating off the organic phase obtained in step (e); and(g) discharging the aqueous phase.

公开(公告)号：US06500988B1

公开(公告)日：2002-12-31

申请号：US09529875

申请日：2000-04-19

Applicant: Friedrich-Wilhelm Ullrich ,  Helmut Fiege

Inventor： Friedrich-Wilhelm Ullrich ,  Helmut Fiege

IPC: C07C31906

CPC classification number: C07C319/06 ,  C07C321/26

Abstract: The invention relates to a particularly advantageous method for producing aryl thiols through the catalytic hydrogenation of diaryldisulphides. According to the invention, the hydrogenation is carried out in a basic alcoholic medium.

Abstract translation: 本发明涉及通过二芳基二硫化物的催化氢化生产芳基硫醇的特别有利的方法。 根据本发明，氢化在碱性醇介质中进行。

公开(公告)号：US06271415B1

公开(公告)日：2001-08-07

申请号：US09529917

申请日：2000-04-19

Applicant: Friedrich-Wilhelm Ullrich ,  Helmut Fiege ,  Wolfgang Eymann

Inventor： Friedrich-Wilhelm Ullrich ,  Helmut Fiege ,  Wolfgang Eymann

IPC: C07C38100

CPC classification number: C07C319/06 ,  C07C381/02 ,  C07C321/26

Abstract: The invention relates to novel S-(4-biphenyl)-thiosulfuric acids and their salts, to a method for producing them from S-(4-biphenyl)-thiosulfinic acids and their salts, and to a method for producing 4-mercaptobiphenyls from the S-(4-biphenyl)-thiosulfuric acids and their salts.

Abstract translation: 本发明涉及新型S-（4-联苯基） - 硫代硫酸及其盐，涉及由S-（4-联苯基） - 硫代亚磺酸及其盐制备它们的方法，以及由4- S-（4-联苯基） - 硫代硫酸及其盐。

公开(公告)号：US5847236A

公开(公告)日：1998-12-08

申请号：US710990

申请日：1996-09-25

Applicant: Franz-Josef Mais ,  Helmut Fiege

Inventor： Franz-Josef Mais ,  Helmut Fiege

IPC: B01J31/02 ,  C07C37/62 ,  C07C39/28

CPC classification number: B01J31/0218 ,  B01J31/26 ,  B01J31/30 ,  C07C37/62

Abstract: 2-Chloro-4-methylphenol is prepared by reacting 4-methylphenol with a chlorinating agent in the presence of a catalyst system of one or more Lewis acids in a total amount of 0.1-10% by weight and one or more diaryl sulphides in a total amount of 0.1-10% by weight, all based on the amount of 4-methylphenol. The reaction temperature is 0.degree.-100.degree. C. The chlorinating agent is used in an amount of 0.5-1.5 mol per mole of 4-methylphenol. The reaction can be carried out until virtually complete consumption of the 4-methylphenol, high isomeric selectivity and high stage selectivity being observed.

Abstract translation: 2-氯-4-甲基苯酚是通过使4-甲基苯酚与氯化剂在总量为0.1-10重量％的一种或多种路易斯酸的催化剂体系存在下反应来制备的，一种或多种二芳基硫化物在 总量为0.1-10重量％，均基于4-甲基苯酚的量。 反应温度为0℃-100℃。氯化剂的用量为每摩尔4-甲基苯酚0.5-1.5摩尔。 反应可以进行直到几乎完全消耗4-甲基苯酚，高异构选择性和高阶段选择性被观察到。